메뉴 건너뛰기




Volumn 53, Issue 1, 2006, Pages 1-5

The effect of aspartame metabolites on human erythrocyte membrane acetylcholinesterase activity

Author keywords

Acetylcholinesterase; Aspartame; Aspartic acid; Methanol; Phenylalanine

Indexed keywords

ACETYLCHOLINESTERASE; ASPARTAME DERIVATIVE; ASPARTIC ACID; DRUG METABOLITE; MEMBRANE ENZYME; METHANOL; PHENYLALANINE;

EID: 27744457424     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2005.07.006     Document Type: Article
Times cited : (36)

References (36)
  • 1
    • 0006313329 scopus 로고
    • Potential effects of the dipeptide sweetener aspartame on the brain
    • W.M. Pardridge Potential effects of the dipeptide sweetener aspartame on the brain Nutr Brain 7 1986 199 241
    • (1986) Nutr Brain , vol.7 , pp. 199-241
    • Pardridge, W.M.1
  • 2
    • 27744514561 scopus 로고
    • An analysis of EDA passive surveillance reports of seizures associated with consumption of aspartame
    • L. Tollefson, and R.J. Barnard An analysis of EDA passive surveillance reports of seizures associated with consumption of aspartame Am J Clin Nutr 43 1986 464 469
    • (1986) Am J Clin Nutr , vol.43 , pp. 464-469
    • Tollefson, L.1    Barnard, R.J.2
  • 3
    • 0023880261 scopus 로고
    • Repeated ingestion of aspartame - Sweetened beverage effect on plasma amino acid concentrations in normal adults
    • L.D. Stegink, L.J. Filer Jr., and G.L. Baker Repeated ingestion of aspartame - sweetened beverage effect on plasma amino acid concentrations in normal adults Metabolism 37 1988 246 251
    • (1988) Metabolism , vol.37 , pp. 246-251
    • Stegink, L.D.1    Filer Jr., L.J.2    Baker, G.L.3
  • 4
    • 0023375561 scopus 로고
    • The aspartame story: A model for the clinical testing of a food additive
    • L.D. Stegink The aspartame story: a model for the clinical testing of a food additive Am J Clin Nutr 46 1987 204 215
    • (1987) Am J Clin Nutr , vol.46 , pp. 204-215
    • Stegink, L.D.1
  • 5
    • 0025897513 scopus 로고
    • Effect of aspartame and protein administered in phenylalanine equivalent doses, on plasma neutral amino acids, aspartate, insulin and glucose in man
    • S.E. Moller Effect of aspartame and protein administered in phenylalanine equivalent doses, on plasma neutral amino acids, aspartate, insulin and glucose in man Pharmacol Toxicol 68 1991 408 412
    • (1991) Pharmacol Toxicol , vol.68 , pp. 408-412
    • Moller, S.E.1
  • 6
    • 0026725086 scopus 로고
    • Aspartame exacerbates EEG spike-wave discharge in children with generalized absence epilepsy: A double blind controlled study
    • P.R. Camfield, C.S. Camfield, J.M. Dooley, K. Gordon, S. Jollymore, and D.F. Weaver Aspartame exacerbates EEG spike-wave discharge in children with generalized absence epilepsy: a double blind controlled study Neurology 42 1992 1000 1003
    • (1992) Neurology , vol.42 , pp. 1000-1003
    • Camfield, P.R.1    Camfield, C.S.2    Dooley, J.M.3    Gordon, K.4    Jollymore, S.5    Weaver, D.F.6
  • 7
    • 27744585465 scopus 로고
    • The possible role of aspartame in seizure induction
    • R.J. Wurthman E. Ritter-Walker Birkhauser Boston
    • R.G. Walton The possible role of aspartame in seizure induction R.J. Wurthman E. Ritter-Walker Dietary phenylalanine and brain function 1988 Birkhauser Boston 159 162
    • (1988) Dietary Phenylalanine and Brain Function , pp. 159-162
    • Walton, R.G.1
  • 8
    • 0028139388 scopus 로고
    • Aspartame and memory loss
    • R.H. Moser Aspartame and memory loss JAMA 272 1994 1543
    • (1994) JAMA , vol.272 , pp. 1543
    • Moser, R.H.1
  • 11
    • 0017058897 scopus 로고
    • Effects of aspartame to young persons during weight reduction
    • R.H. Knopp, K. Brandt, and R.A. Arky Effects of aspartame to young persons during weight reduction J Toxicol Environ Health 2 1976 417 428
    • (1976) J Toxicol Environ Health , vol.2 , pp. 417-428
    • Knopp, R.H.1    Brandt, K.2    Arky, R.A.3
  • 13
    • 0034604525 scopus 로고    scopus 로고
    • Acute effects of aspartame on aggression and neurochemistry in rats
    • A.L. Goerss, G.C. Wagner, and W.L. Hill Acute effects of aspartame on aggression and neurochemistry in rats Life Sci 67 2000 1325 1329
    • (2000) Life Sci , vol.67 , pp. 1325-1329
    • Goerss, A.L.1    Wagner, G.C.2    Hill, W.L.3
  • 14
    • 0026102093 scopus 로고
    • Amino acids, monoamines and audiogenic seizures in genetically epilepsy-prone rats: Effects of aspartame
    • J.W. Dailey, S.M. Lasley, R.L. Burger, A.F. Bettendorf, P.K. Mishra, and P.C. Jobe Amino acids, monoamines and audiogenic seizures in genetically epilepsy-prone rats: effects of aspartame Epilepsy Res 8 1991 122 133
    • (1991) Epilepsy Res , vol.8 , pp. 122-133
    • Dailey, J.W.1    Lasley, S.M.2    Burger, R.L.3    Bettendorf, A.F.4    Mishra, P.K.5    Jobe, P.C.6
  • 17
    • 0036867140 scopus 로고    scopus 로고
    • Reduced acetylcholinesterase activity in erythrocyte membranes from patients with phenylketonuria
    • S. Tsakiris, K.H. Schulpis, J. Tjamouranis, H. Michelakakis, and G.A. Karikas Reduced acetylcholinesterase activity in erythrocyte membranes from patients with phenylketonuria Clin Biochem 35 2002 615 619
    • (2002) Clin Biochem , vol.35 , pp. 615-619
    • Tsakiris, S.1    Schulpis, K.H.2    Tjamouranis, J.3    Michelakakis, H.4    Karikas, G.A.5
  • 18
    • 0019156271 scopus 로고
    • Changes in some cytoplasmic enzymes from red cells fractionated into age groups by centrifugation in Ficoll/Triosil gradients. Comparison of normal humans and patients with Duchenne muscular dystrophy
    • D.A. Galbraith, and D.C. Watts Changes in some cytoplasmic enzymes from red cells fractionated into age groups by centrifugation in Ficoll/Triosil gradients. Comparison of normal humans and patients with Duchenne muscular dystrophy Biochem J 191 1980 63 70
    • (1980) Biochem J , vol.191 , pp. 63-70
    • Galbraith, D.A.1    Watts, D.C.2
  • 19
    • 48749141299 scopus 로고
    • Modifications in the activities of membrane-bound enzymes during in vivo ageing of human and rabbit erythrocytes
    • K. Kamber, A. Poyiagi, and G. Delikonstantinos Modifications in the activities of membrane-bound enzymes during in vivo ageing of human and rabbit erythrocytes Comp Biochem Physiol B 77B 1984 95 99
    • (1984) Comp Biochem Physiol B , vol.77 , pp. 95-99
    • Kamber, K.1    Poyiagi, A.2    Delikonstantinos, G.3
  • 21
    • 33644811612 scopus 로고
    • A new and rapid colorimetric determination of acetylcholinesterase activity
    • G.L. Ellman, D. Courtney, V. Andres, and R.M. Featherstone A new and rapid colorimetric determination of acetylcholinesterase activity Biochem Pharmacol 7 1961 85 88
    • (1961) Biochem Pharmacol , vol.7 , pp. 85-88
    • Ellman, G.L.1    Courtney, D.2    Andres, V.3    Featherstone, R.M.4
  • 23
    • 0018647092 scopus 로고
    • A review of the metabolism of the aspartyl moiety of aspartame in experimental animals and man
    • R.E. Ranney, and J.A. Oppermann A review of the metabolism of the aspartyl moiety of aspartame in experimental animals and man J Environ Pathol Toxicol 2 1979 979 985
    • (1979) J Environ Pathol Toxicol , vol.2 , pp. 979-985
    • Ranney, R.E.1    Oppermann, J.A.2
  • 24
    • 0033588435 scopus 로고    scopus 로고
    • Comments on the purported generation of formaldehyde and adduct formation from the sweetener
    • T.R. Tephly Comments on the purported generation of formaldehyde and adduct formation from the sweetener Life Sci 65 1999 PL157 PL160
    • (1999) Life Sci , vol.65
    • Tephly, T.R.1
  • 26
    • 0026727310 scopus 로고
    • Methanol poisoning
    • J.A. Kruse Methanol poisoning Intensive Care Med 18 1992 391 397
    • (1992) Intensive Care Med , vol.18 , pp. 391-397
    • Kruse, J.A.1
  • 27
    • 0022649417 scopus 로고
    • Serum formate concentrations in methanol intoxication as a criterion for hemodialysis
    • J.D. Osterloh, S.M. Pond, S. Grady, and C.E. Becker Serum formate concentrations in methanol intoxication as a criterion for hemodialysis Ann Intern Med 1986 2000 2003
    • (1986) Ann Intern Med , pp. 2000-2003
    • Osterloh, J.D.1    Pond, S.M.2    Grady, S.3    Becker, C.E.4
  • 28
    • 0030778547 scopus 로고    scopus 로고
    • Glutathione consumption and inactivation of glutathione-related enzymes in liver, erythrocytes and serum of rats after methanol intoxication
    • E. Skrzydlewska, and R. Farbiszewski Glutathione consumption and inactivation of glutathione-related enzymes in liver, erythrocytes and serum of rats after methanol intoxication Arch Toxicol 71 1997 741 745
    • (1997) Arch Toxicol , vol.71 , pp. 741-745
    • Skrzydlewska, E.1    Farbiszewski, R.2
  • 29
    • 0036203427 scopus 로고    scopus 로고
    • Cytotoxic effects of methanol formaldehyde and formate on dissociated rat thymocytes: A possibility of aspartame toxicity
    • Y. Oyama, H. Sakai, T. Arata, Y. Okano, N. Akaike, and K. Sakai Cytotoxic effects of methanol formaldehyde and formate on dissociated rat thymocytes: A possibility of aspartame toxicity Cell Biol Toxicol 18 2002 43 50
    • (2002) Cell Biol Toxicol , vol.18 , pp. 43-50
    • Oyama, Y.1    Sakai, H.2    Arata, T.3    Okano, Y.4    Akaike, N.5    Sakai, K.6
  • 31
    • 0029940994 scopus 로고    scopus 로고
    • A flow cytometric study of N-methyl-d-aspartate effects on dissociated cerebellar cells
    • F. Sureda, A. Camins, R. Trullas, J. Camarasa, and E. Escubedo A flow cytometric study of N-methyl-d-aspartate effects on dissociated cerebellar cells Brain Res 723 1996 110 114
    • (1996) Brain Res , vol.723 , pp. 110-114
    • Sureda, F.1    Camins, A.2    Trullas, R.3    Camarasa, J.4    Escubedo, E.5
  • 32
    • 0029943110 scopus 로고    scopus 로고
    • Continuing the search for cholinergic factors in cognitive dysfunction
    • R.W. Russell Continuing the search for cholinergic factors in cognitive dysfunction Life Sci 58 1996 1965 1970
    • (1996) Life Sci , vol.58 , pp. 1965-1970
    • Russell, R.W.1
  • 34
    • 0029078203 scopus 로고
    • Nicotinic and muscarinic receptors in the rat prefrontal cortex: Differential roles in working memory, response selection and effortful processing
    • S. Granon, B. Poucet, C. Thinus-Blanc, J.P. Changeux, and C. Vidal Nicotinic and muscarinic receptors in the rat prefrontal cortex: differential roles in working memory, response selection and effortful processing Psychopharmacology (Berl) 119 1995 139 144
    • (1995) Psychopharmacology (Berl) , vol.119 , pp. 139-144
    • Granon, S.1    Poucet, B.2    Thinus-Blanc, C.3    Changeux, J.P.4    Vidal, C.5
  • 35
    • 0033030642 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptors in the hippocampus, neocortex and amygdala: A review of immunocytochemical localization in relation to learning and memory
    • E.A. Van der Zee, and P.G. Luiten Muscarinic acetylcholine receptors in the hippocampus, neocortex and amygdala: a review of immunocytochemical localization in relation to learning and memory Prog Neurobiol 58 1999 409 471
    • (1999) Prog Neurobiol , vol.58 , pp. 409-471
    • Van Der Zee, E.A.1    Luiten, P.G.2
  • 36
    • 0026345148 scopus 로고
    • Effect of tyrosine on the potentiation by aspartame and phenylalanine of metrazol-induced convulsions in rats
    • G. Guiso, L. Diomede, M. Romano, S. Caccia, S. Sarati, and M. Salmona Effect of tyrosine on the potentiation by aspartame and phenylalanine of metrazol-induced convulsions in rats Food Chem Toxicol 29 1991 855 857
    • (1991) Food Chem Toxicol , vol.29 , pp. 855-857
    • Guiso, G.1    Diomede, L.2    Romano, M.3    Caccia, S.4    Sarati, S.5    Salmona, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.