Acute methanol intoxication generates free radicals in rats: An ESR spin trapping investigation

Free Radical Biology and Medicine

Volumn 28, Issue 7, 2000, Pages 1106-1114

  Kadiiska, Maria B ^a   Mason, Ronald P ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Free radicals; Methanol; Rat

Indexed keywords

4 METHYLPYRAZOLE; ALCOHOL DEHYDROGENASE; FREE RADICAL; METHANOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; MALE; METHANOL POISONING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ASPARTATE AMINOTRANSFERASES; BILE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; HYDROXYL RADICAL; INJECTIONS, INTRAPERITONEAL; INTUBATION, GASTROINTESTINAL; L-IDITOL 2-DEHYDROGENASE; LIVER; MALE; METHANOL; NITROGEN OXIDES; RATS; RATS, SPRAGUE-DAWLEY; SPIN LABELS; SPIN TRAPPING;

ANIMALIA;

EID: 0034122809     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(00)00203-3     Document Type: Article

References (56)

1. Fishbein, L., ed. Methanol. Environmental Health Criteria 196. Geneva: World Health Organization; 1997.
2. Schiavone F.M., Cantor F.D., Brogan G.X. Ethylene glycol, methanol, and isopropyl alcohol. Viccellio P. Handbook of Medical Toxicology. 1993;183-197 Little, Brown and Company, Boston/Toronto/London.
3. Litovitz T.L., Schmitz B.F., Bailey K.M. 1989 Annual report of the American Association of Poison Control Centers National Data Collection System. Am. J. Emerg. Med. 8:1990;429-442.
4. Medinsky, M. A.; Dorman, D. C.; Bond, J. A.; Moss, O. R.; Janszen, D. B.; Everitt, J. I. Pharmacokinetics of methanol and formate in female cynomolgus monkeys exposed to methanol vapors. Health Effects Institute Research Report; 1997.No. 77.
5. Jacobsen D., McMartin K.E. Methanol and ethylene glycol poisonings. Mechanism of toxicity, clinical course, diagnosis, and treatment. Med. Toxicol. 1:1986;309-334.
6. Johlin F.C., Swain E., Smith C., Tephly T.R. Studies on the mechanism of methanol poisoning purification and comparison of rat and human liver 10-formlytetrahydrofolate dehydrogenase . Mol. Pharmacol. 35:1989;745-750.
7. Liesivuori J., Savolainen H. Methanol and formic acid toxicity biochemical mechanisms . Pharmacol. Toxicol. 69:1991;157-163.
8. McMartin K.E., Ambre J.J., Tephly T.R. Methanol poisoning in human subjects. Role for formic acid accumulation in the metabolic acidosis. Amer. J. Med. 68:1980;414-418.
9. Anderson T.J., Shuaib A., Becker W.J. Methanol poisoning factors associated with neurologic complications . Can. J. Neurol. Sci. 16:1989;432-435.
10. Eells J.T. Methanol-induced visual toxicity in the rat. J. Pharmacol. Exp. Ther. 257:1991;56-63.
11. Eells J.T., Salzman M.M., Lewandowski M.F., Murray T.G. Formate-induced alterations in retinal function in methanol-intoxicated rats. Toxicol. Appl. Pharmacol. 140:1996;58-69.
12. Gonda A., Gault H., Churchill D., Hollomby D. Hemodialysis for methanol intoxication. Am. J. Med. 64:1978;749-758.
13. Baud F.J., Galliot M., Astier A., Bien D.V., Garnier R., Likforman J., Bismuth C. Treatment of ethylene glycol poisoning with intravenous 4-methylpyrazole. N. Engl. J. Med. 319:1988;97-100.
14. Blomstrand R., Ostling-Wintzell H., Lof A., McMartin K., Tolf B.-R., Hedstrom K.-G. Pyrazoles as inhibitors of alcohol oxidation and as important tools in alcohol research an approach to therapy against methanol poisoning . Proc. Natl. Acad. Sci. USA. 76:1979;3499-3503.
15. Magnusson G., Nyberg J.-A., Bodin N.-O., Hansson E. Toxicity of pyrazole and 4-methylpyrazole in mice and rats. Experientia. 28:1972;1198-1200.
16. Bradford B.U., Forman D.T., Thurman R.G. 4-Methylpyrazole inhibits fatty acyl coenzyme synthetase and diminishes catalase-dependent alcohol metabolism has the contribution of alcohol dehydrogenase to alcohol metabolism been previously overestimated? Mol. Pharmacol. 43:1993;115-119.
17. Tephly T.R., Parks R.E., Mannering G.J. Methanol metabolism in the rat. J. Pharmacol. Exp. Ther. 143:1964;292-300.
18. Eells J.T., Makar A.B., Noker P.E., Tephly T.R. Methanol poisoning and formate oxidation in nitrous oxide-treated rats. J. Pharmacol. Exp. Ther. 217:1981;57-61.
19. Eells J.T., Black K.A., Tedford C.E., Tephly T.R. Methanol toxicity in the monkey effects of nitrous oxide and methionine . J. Pharmacol. Exp. Ther. 227:1983;349-353.
20. Thurman R.G., Ley H.G., Scholz R. Hepatic microsomal ethanol oxidation. Hydrogen peroxide formation and the role of catalase. Eur. J. Biochem. 25:1972;420-430.
21. Albano E., Tomasi A., Goria-Gatti L., Dianzani M.U. Spin trapping of free radical species produced during the microsomal metabolism of ethanol. Chem. Biol. Interact. 65:1988;223-234.
22. Rashba-Step J., Turro N.J., Cederbaum A.I. ESR studies on the production of reactive oxygen intermediates by rat liver microsomes in the presence of NADPH or NADH. Arch. Biochem. Biophys. 300:1993;391-400.
23. Reinke L.A., Moore D.R., Hague C.M., McCay P.B. Metabolism of ethanol to 1-hydroxyethyl radicals in rat liver microsomes comparative studies with three spin trapping agents . Free Radic. Res. 21:1994;213-222.
24. Knecht K.T., Thurman R.G., Mason R.P. Role of superoxide and trace transition metals in the production of α-hydroxyethyl radical from ethanol by microsomes from alcohol dehydrogenase-deficient deer mice. Arch. Biochem. Biophys. 303:1993;339-348.
25. Knecht K.T., Bradford B.U., Mason R.P., Thurman R.G. In vivo formation of a free radical metabolite of ethanol. Mol. Pharmacol. 38:1990;26-30.
26. Moore D.R., Reinke L.A., McCay P.B. Metabolism of ethanol to 1-hydroxyethyl radicals in vivo detection with intravenous administration of α-(4-pyridyl-1-oxide)-N-t-butylnitrone . Mol. Pharmacol. 47:1995;1224-1230.
27. Reinke L.A., Kotake Y., McCay P.B., Janzen E.G. Spin-trapping studies of hepatic free radicals formed following the acute administration of ethanol to rats in vivo detection of 1-hydroxyethyl radicals with PBN . Free Radic. Biol. Med. 11:1991;31-39.
28. Iimuro Y., Bradford B.U., Gao W., Kadiiska M., Mason R.P., Stefanovic B., Brenner D.A., Thurman R.G. Detection of α-hydroxyethyl free radical adducts in the pancreas after chronic exposure to alcohol in the rat. Mol. Pharmacol. 50:1996;656-661.
29. Wacker W.E.C., Ulmer D.D., Vallee B.L. Metalloenzymes and myocardial infarction. II. Malic and lactic dehydrogenase activities and zinc concentrations in serum. N. Eng. J. Med. 255:1956;449-456.
30. Wroblewski F., LaDue J.S. Serum glutamic pyruvic transaminase in cardiac and hepatic disease. Proc. Soc. Exp. Biol. Med. 91:1956;569-571.
31. Asada M., Galambos J.T. Sorbitol dehydrogenase and hepatocellular injury an experimental and clinical study . Gastroenterology. 44:1963;578-587.
32. Mashige F., Tanaka N., Maki A., Kamei S., Yamanaka M. Direct spectrophotometry of total bile acids in serum. Clin. Chem. 27:1981;1352-1356.
33. 4 in the perfused rat liver and in vivo. J. Biol. Chem. 261:1986;4542-4548.
34. Duling D.R. Simulation of multiple isotropic spin-trap ESR spectra. J. Magn. Reson. B. 104:1994;105-110.
35. Kadiiska M.B., Hanna P.M., Hernandez L., Mason R.P. In vivo evidence of hydroxyl radical formation after acute copper and ascorbic acid intake electron spin resonance spin-trapping investigation . Mol. Pharmacol. 42:1992;723-729.
36. Mottley C., Mason R.P. Nitroxide radical adducts in biology chemistry, applications, and pitfalls . Berliner L.J., Reuben J. Biological magnetic resonance. Vol. 8. 1989;489-546 Plenium Publishing Corp, New York.
37. Sridhar R., Beaumont P.C., Powers E.L. Fast kinetics of the reaction of hydroxyl radicals with nitrone spin traps. J. Radioanal. Nucl. Chem. 101:1986;227-237.
38. Carmichael A.J., Makino K., Riesz P. Quantitative aspects of ESR and spin trapping of hydroxyl radicals and hydrogen atoms in gamma-irradiated aqueous solutions. Radiat. Res. 100:1984;222-234.
39. Sentjurc M., Mason R.P. Inhibition of radical adduct reduction and reoxidation of the corresponding hydroxylamines in in vivo spin trapping of carbon tetrachloride-derived radicals. Free Radic. Biol. Med. 13:1992;151-160.
40. Stoyanovsky D.A., Cederbaum A.I. Metabolism of carbon tetrachloride to trichloromethyl radical an ESR and HPLC-EC study . Chem. Res. Toxicol. 12:1999;730-736.
41. Jovanovic S.V., Steenken S., Simic M.G. One electron reduction potentials of 5-indoxyl radicals. A pulse radiolysis and laser photolysis study. J. Phys. Chem. 94:1990;3583-3588.
42. Jovanovic S.V., Tosic M., Simic M.G. Use of the Hammett correlation and σ+ for calculation of one-electron redox potentials of antioxidants. J. Phys. Chem. 95:1991;10824-10827.
43. Adams G.E., Willson R.L. Pulse radiolysis studies on the oxidation of organic radicals in aqueous solution. Trans. Faraday Soc. 65:1969;2981-2987.
44. 2 elimination from α-hydroxyalkylperoxyl radicals in aqueous solution. Photochem. Photobiol. 28:1978;639-644.
45. Akhlaq M.S., Al-Baghdadi S., von Sonntag C. On the attack of hydroxyl radicals on polyhydric alcohols and sugars and the reduction of the SO-formed radicals by 1,4-dithiothreitol. Carbohyd. Res. 164:1987;71-83.
46. Eriksen T.E., Fransson G. Radical-induced oxidation of glutathione in alkaline aqueous solution. Radiat. Phys. Chem. 32:1988;163-167.
47. Harman L.S., Carver D.K., Schreiber J., Mason R.P. One- and two-electron oxidation of reduced glutathione by peroxidases. J. Biol. Chem. 261:1986;1642-1648.
48. Knecht K.T., Adachi Y., Bradford B.U., Iimuro Y., Kadiiska M., Xuang Q.-H., Thurman R.G. Free radical adducts in the bile of rats treated chronically with intragastric alcohol inhibition by destruction of Kupffer cells . Mol. Pharmacol. 47:1995;1028-1034.
49. Moncada C., Torres V., Varghese G., Albano E., Israel Y. Ethanol-derived immunoreactive species formed by free radical mechanisms. Mol. Pharmacol. 46:1994;786-791.
50. Rao, D. N. R.; Yang, M.-X.; Lasker, J. M.; Cederbaum, A. I. 1-hydroxyethyl radical formation during NADPH- and NADH-dependent oxidation of ethanol by human liver microsomes. Mol. Pharmacol. 49:814-821; 1996.
51. Chemical Industry Institute of Toxicology. Methanol. In: CIIT. CIIT 1994 Annual Report. Research Triangle Park, NC: CIIT; 1994:13-16.
52. Skrzydlewska E., Farbiszewski R. Liver and serum antioxidant status after methanol intoxication in rats. Acta Biochimica Polonica. 44:1997;139-146.
53. Reinke L.A., Lai E.K., DuBose C.M., McCay P.B. Reactive free radical generation in vivo in heart and liver of ethanol-fed rats correlation with radical formation in vitro . Proc. Natl. Acad. Sci. USA. 84:1987;9223-9227.
54. Kato S., Alderman J., Lieber C.S. Ethanol metabolism in alcohol dehydrogenase deficient deermice is mediated by the microsomal ethanol oxidizing system, not by catalase. Alcohol Alcohol. 1:(Suppl.):1987;231-234.
55. Thurman R.G., Handler J.A. New perspectives in catalase-dependent ethanol metabolism. Drug. Metab. Rev. 20:1989;679-688.
56. Tampier L., Quintanilla M.E. Effect of 3-amino-1,2,4-triazole on the hypothermic effect of ethanol and on ethanol tolerance development. Alcohol. 8:1991;279-282.