D(+) galactosamine induced oxidative and nitrosative stress-mediated renal damage in rats via NF-κB and inducible nitric oxide synthase (iNOS) pathways is ameliorated by a polyphenol xanthone, mangiferin

Free Radical Research

Volumn 46, Issue 2, 2012, Pages 116-132

  Ghosh, Manoranjan ^a   Das, Joydeep ^a   Sil, Parames C ^a  

^a BOSE INSTITUTE   (India)

Author keywords

antioxidant; apoptosis; D(+) galactosamine; mangiferin; nephrotoxicity; reactive oxygen species

Indexed keywords

CASPASE 3; CYTOCHROME C; GALACTOSAMINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MANGIFERIN; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; XANTHONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOSOL; HISTOPATHOLOGY; KIDNEY INJURY; MALE; NEPHROTOXICITY; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; RENAL PROTECTION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BLOOD UREA NITROGEN; CELL-FREE SYSTEM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CREATININE; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; GALACTOSAMINE; KIDNEY; MALE; MALONDIALDEHYDE; MEMBRANE POTENTIAL, MITOCHONDRIAL; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PROTEIN CARBONYLATION; RANDOM ALLOCATION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RENAL INSUFFICIENCY; TUMOR NECROSIS FACTOR-ALPHA; XANTHONES;

RATTUS;

EID: 84856254755     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2011.644240     Document Type: Article

References (46)

1. Manna P, Sinha M, Sil PC. Galactosamine-induced hepatotoxic effect and hepatoprotective role of a protein isolated from the herb Cajanus indicus L in vivo. J Biochem Mol Toxicol 2007; 21: 13-23. (Pubitemid 46555355)
2. Sinha M, Manna P, Sil PC. Amelioration of galactosamineinduced nephrotoxicity by a protein isolated from the leaves of the herb, Cajanus indicus L. BMC Compl Alternative Med 2007;7:11.
3. Sracyn M, Kozlowski W, Wanikowicz Z. Description of an experimental model of hepatorenal syndrome in Wistar rats. Pol Merkur Lekarski 2004;17:119-122. (Pubitemid 39295668)
4. Gezginci-Oktayoglu S, Tunali S, Yanardag R, Bolkent S. Effects of Z-FA.FMK on D-galactosamine/tumor necrosis factor-alpha-induced kidney injury and oxidative stress in mice. Mol Cell Biochem 2008;309:9-20.
5. Tapalaga D, Tiegs G, Angermüller S. NFkB and caspase-3 activity in apoptotic hepatocytes of galactosamine-sensitizedmice treated with TNF-α. J Histochem Cytochem 2002;50:1599-1609. (Pubitemid 36078125)
6. Catal T, Sacan O, Yanardag R, Bolkent S. Protective effects of antioxidant combination against D-galactosamine-induced kidney injury in rats. Cell Biochem Funct 2010;28:107-113.
7. Das J, Ghosh J, Manna P, Sil PC. Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation. Toxicology 2010;269:24-34.
8. Ghosh J, Das J, Manna P, Sil PC. Acetaminophen induced renal injury via oxidative stress and TNF-alpha production: Therapeutic potential of arjunolic acid. Toxicology 2010;268: 8-18.
9. Manna P, Sinha M, Sil PC. Prophylactic role of arjunolic acid in response to streptozotocin mediated diabetic renal injury: Activation of polyol pathway and oxidative stress responsive signaling cascades. Chem Biol Interact 2009;181:297-308.
10. Manna P, Sinha M, Sil PC. Taurine plays a benefi cial role against cadmium-induced oxidative renal dysfunction. Amino Acids 2009;36:417-428.
11. Roy A, Manna P, Sil PC. Prophylactic role of taurine on arsenic mediated oxidative renal dysfunction via MAPKs/NFkappaB and mitochondria dependent pathways. Free Radic Res 2009;43:995-1007.
12. Sanchez GM, Re L, Giluliani A, Nuonez-Selles AJ, Davison GP, Leon-Fernandez OS. Protective effect of Mangifera indica L. extract, mangiferin and selected antioxidants against TPA-induced biomolecules oxidation and peritoneal macrophage activation in mice. Pharmacol Res 2000; 42:565-573.
13. Li H, Miyahara T, Tezuka Y, Namba T, Nemoto N, Tonami S. The effect of kampo formulae on bone resorption in vitro and in vivo. I. Active constitutents of Tsu-kan-gan. Biol Pharmaceut Bull 1998;21:1322-1326. (Pubitemid 29021794)
14. G uha S, Ghosal S, Chattopadhay U. Antitumor, immunomodulatory and anti-HIV effect mangiferin, a naturally occurring glycosylxanthone. Chemotherapy 1996;42:443-451. (Pubitemid 26379933)
15. Yoosook C, Bunyapraphatsara N, Boonyakiat Y, Kantasuk C. Anti-herpes simplex virus activities of crude water extract of thai medicinal plants. Phytomedicine 2006;6:411-419.
16. Leiro JM, Alvarez E, Arranz JA, Siso IG, Orallo F. In vitro effects of mangiferin on superoxide concentration and expression of the inducible nitric oxide synthase, tumour necrosis factor-a and transforming growth factor-b genes. Biochem Pharmacol 2003;65:1361-1371. (Pubitemid 36407787)
17. Maria RCE, Maria VSG, Carlos M. Molecular mechamisms of neroprotection by two natural antioxidant polyphenols. Cell Calcium 2009;45:358-368.
18. Muruganandan S, Gupta S, Kataria M, Lal J, Gupta PK. Mangiferin protects the streptozotocin-induced oxidative damage to cardiac and renal tissues in rats. Toxicology 2002;176:165-173. (Pubitemid 34692590)
19. Singh SK, Kumar Y, Kumar SS, Sharma VK, Dua K, Samad A. Antimicrobial evaluation of mangiferin analogues. Ind J Pharm Sci 2009;71:328-331.
20. Blois MS. Antioxidant determination by use of a stable free radical. Nature 1958;29:1199-1200.
21. Manna P, Sinha M, Sil PC. Protective role of arjunolic acid in response to streptozotocin-induced type-I diabetes via the mitochondrial dependent and independent pathways. Toxicology 2009;257:53-63.
22. Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR. Analysis of nitrate, nitrite, and [15N] nitrate in biological fl uids. Anal Biochem 1982;126:131-138. (Pubitemid 13203451)
23. Marcocci I, Marguire JJ, Droy-l efaiz MT, Packer L. The nitric oxide scavenging properties Ginkgo biloba extract. Biochem Biophys Res Commun 1994;201:748-755. (Pubitemid 24206935)
24. Nash T. The colorimetric estimation of formaldehyde by means of the Hantzsch reaction. J Biochem 1953;55:416-421.
25. Pushpavalli G, Veeramani C, Pugalendi KV. Effect of Piper betle on plasma antioxidant status and lipid profi le against D-galactosamine-induced hepatitis in rats. Redox Rep 2009; 14:7-12.
26. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72: 248-254.
27. LeBel CP, Bondy SC. Sensitive and rapid quantitation of oxygen reactive species formation in rat synaptosomes. Neurochem Int 1990;17:435-440. (Pubitemid 20274589)
28. Kim JD, McCarter RJM, Yu BP. Influence of age, exercise and dietary restriction on oxidative stress in rats. Aging Clin Exp Res 1996;8:123-129.
29. Das J, Ghosh J, Manna P, Sinha M, Sil PC. Taurine protects rat testes against NaAsO 2-induced oxidative stress and apoptosis via mitochondrial dependent and independent pathways. Toxicol Lett 2009;187:201-210.
30. Esterbauer H, Cheeseman, KH. Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Meth Enzymol 1990;186:407-421. (Pubitemid 20279982)
31. Manna P, Sinha M, Sil PC. Protection of arsenic-induced testicular oxidative stress by arjunolic acid. Redox Report 2008;13:67-77. (Pubitemid 351546452)
32. Das J, Ghosh J, Manna P, Sinha M, Sil PC. Arsenic-induced oxidative cerebral disorders: Protection by taurine. Drug Chem Toxicol 2009;32:93-102.
33. Ghosh J, Das J, Manna P, Sil, PC. Taurine prevents arsenicinduced cardiac oxidative stress and apoptotic damage: Role of NF-κB, p38 and JNK MAPK pathway. Toxicol Appl Pharmacol 2009;240:73-87.
34. Sinha M, Manna P, Sil PC. Cadmium-induced neurological disorders: prophylactic role of taurine. J Appl Toxicol 2008;28:974-986.
35. Chandrasekaran V, Hsu D, Liu M. The protective effect of sesamol against mitochondrial oxidative stress and hepatic injury in acetaminophen-overdosed rats. Shock 2009;32:89-93.
36. Mingatto FE, Rodrigues T, Pigoso AA, Uyemura SA, Curti C, Santos AC. The critical role of mitochondrial energetic impairment in the toxicity of nimesulide to hepatocytes. J Pharmacol Exp Ther 2003;303:601-607. (Pubitemid 35231231)
37. Anand R, Harry D, Holt S, Milner P, Dashwood M, Goodier D, et al. Endothelin is an important determinant of renal function in rat model of acute liver and renal failure. Gut 2006; 50:11-117.
38. Fridovich I. Superoxide radical and superoxide dismutase. Acc Chem Res 1972;5:321-323.
39. Jones P, Suggett A. The catalase-hydrogen peroxide system. A theoretical appraisal of the mechanism of catalase action. Biochem J 1968;110:621-629.
40. Ricardo SD, Bertram JF, Ryan GB. Reactive oxygen species in puromycin aminonucleoside nephrosis: in vitro studies. Kidney Int 1994;45:1057-1069. (Pubitemid 24234723)
41. Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ. Bcl-2 functions in an antioxidant pathway to apoptosis. Cell 1993;75:241-251. (Pubitemid 23320288)
42. Lin BR, Yu CJ, Chen WC, Lee HS, Chang HM, Lee YC, et al. Green tea extract supplement reduces D-galactosamineinduced acute liver injury by inhibition of apoptotic and proinflammatory signaling. J Biomed Sci 2009;16:35.
43. Lóp ez-Sán chez LM, Collado JA, Corrales FJ, Lóp ez-Cillero P, Montero JL, Fraga E, et al. Snitrosation of proteins during d-galactosamine-induced cell death in human hepatocytes. Free Radic Res 2007;41:50-61. (Pubitemid 44896874)
44. Siendones E, Fouad D, Abou-Elella MKE. Role of nitric oxide in d galactosamine-induced cell death and its protection by PGE(1) in cultured hepatocytes. Nitric Oxide 2003;8: 133-143. (Pubitemid 36287222)
45. Baldwin AS. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 1996;14:649-683.
46. Verzola D, Bertolotto MB, Villaggio B, Ottonello L, Dallegri F, Frumento G, et al. Taurine prevents apoptosis induced by high glucose in human tuble renal cells. J Investig Med 2002;50:443-451. (Pubitemid 35278685)