Epidermal growth factor receptor (EGFR)-mediated positive feedback of protein-tyrosine phosphatase ε (PTPε) on ERK1/2 and AKT protein pathways is required for survival of human breast cancer cells

Journal of Biological Chemistry

Volumn 287, Issue 5, 2012, Pages 3433-3444

  Nunes Xavier, Caroline E ^a   Elsons, Ari ^b   Pulido, Rafael ^a  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AKT ACTIVATION; BREAST CANCER; BREAST CANCER CELLS; EPIDERMAL GROWTH FACTOR RECEPTORS; HUMAN BREAST CANCER CELLS; HUMAN CANCER; MCF-7 CELLS; PROTEIN PATHWAYS; PROTEIN-TYROSINE PHOSPHATASE; SUSTAINED ACTIVATION; TYROSINE KINASE; TYROSINE PHOSPHORYLATION; UP-REGULATION;

ACTIVATION ANALYSIS; AMINO ACIDS; ANCHORAGES (FOUNDATIONS); CELL CULTURE; DISEASES; FEEDBACK; PHOSPHATASES; PHOSPHORYLATION; PROTEINS;

CELLS;

EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE EPSILON;

ANCHORAGE INDEPENDENT GROWTH; ARTICLE; BREAST CANCER; CANCER CELL; CELL SURVIVAL; CELL VIABILITY; COLONY FORMATION; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; UPREGULATION;

BREAST NEOPLASMS; CARCINOGENS; CELL LINE, TUMOR; CELL SURVIVAL; ENZYME ACTIVATION; FEMALE; FIBROBLAST GROWTH FACTORS; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 4; TETRADECANOYLPHORBOL ACETATE;

EID: 84856252361     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.293928     Document Type: Article

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