Protein kinase Cα negatively regulates cell spreading and motility in MDA-MB-231 human breast cancer cells downstream of epidermal growth factor receptor

Biochemical and Biophysical Research Communications

Volumn 307, Issue 4, 2003, Pages 839-846

  Gauthier, Mona L ^a,b   Torretto, Cheryl ^a   Ly, John ^a   Francescutti, Valerie ^a   O'Day, Danton H ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Breast cancer cells; Cell motility; Cell spreading; EGFR; Phorbol esters; Protein kinase C

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN KINASE C ACTIVATOR; PROTEIN KINASE C ALPHA; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C IOTA; PROTEIN KINASE C LAMBDA; UNCLASSIFIED DRUG; EPIDERMAL GROWTH FACTOR; PRKCA PROTEIN, HUMAN;

ARTICLE; BREAST CANCER; CANCER CELL; CELL MOTILITY; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; HUMAN; HUMAN CELL; METASTASIS; PRIORITY JOURNAL; BREAST TUMOR; CELL CULTURE; CELL MOTION; CELL SIZE; DRUG ANTAGONISM; ENZYMOLOGY; FEMALE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

BREAST NEOPLASMS; CELL MOVEMENT; CELL SIZE; EPIDERMAL GROWTH FACTOR; FEMALE; HUMANS; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED;

EID: 0038444776     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)01273-7     Document Type: Article

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