Tyrosine kinase signalling in breast cancer

Breast Cancer Research

Volumn 2, Issue 3, 2000, Pages 154-157

  Hynes, N E ^a  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

Cortactin; ErbB receptor tyrosine kinases; Fibroblast growth factor receptor; G protein coupled receptors; Insulin like growth factor 1; Src

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TRASTUZUMAB;

BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL; CELL PROLIFERATION; ENVIRONMENT; ENZYME ACTIVATION; HORMONAL REGULATION; HUMAN; MOUSE; NONHUMAN; NOTE; PARACRINE SIGNALING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

BREAST NEOPLASMS; FEMALE; GENES, ERBB; GENES, SRC; HUMANS; INSULIN-LIKE GROWTH FACTOR I; PROTEIN-TYROSINE KINASES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, FIBROBLAST GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 0034469080     PISSN: 14655411     EISSN: None     Source Type: Journal    
DOI: 10.1186/bcr48     Document Type: Note

References (26)

1. Switching signals on or off by receptor dimerization
2. Tyrosine kinase signalling in breast cancer. ErbB family receptor tyrosine kinases in breast cancer
3. Tyrosine kinase signalling in breast cancer: Tyrosine kinase mediated signal transduction in transgenic mouse models of human breast cancer
4. Tyrosine kinase signalling in breast cancer: Epidermal growth factor receptor: Convergence point for signal transduction and diversification
5. Tyrosine kinase signalling in breast cancer: Epidermal growth factor receptor and c-Src interactions in breast cancer
6. Tyrosine kinase signalling in breast cancer: Insulin-like growth factors and their receptors in breast cancer
7. Tyrosine kinase signalling in breast cancer: Fibroblast growth factors and their receptors
8. Tyrosine kinase signalling in breast cancer: Modulation of tyrosine kinase signalling in human breast cancer through altered expression of signalling intermediates
9. Human breast cancer: Correlation of relapse and survival with the amplification of the HER2/neu oncogene
10. c-Src mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function
11. Activation of Src family kinases in Neu-induced mammary tumors correlates with their association with distinct sets of tyrosine phosphorylated proteins in vivo
12. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
13. The product of the EMS1 gene, amplified and overexpressed in human carcinoma, is homologous to a v-src substrate and is located in cell-substratum contact sites
14. The insulin-like growth factor I receptor: A key to tumor growth?
15. Oncogenes and cell death
16. Enhancement of insulin-like growth factor signaling in human breast cancer: Estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo
17. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
18. ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
19. Epidermal growth factor-related peptides and their receptors in human malignancies
20. Active signaling by Neu in transgenic mice
21. Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions
22. Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: Implications for human breast cancer
23. Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells
24. Kip1-Cdk2 complex formation: Receptor overexpression does not determine growth dependency
25. HER2 monoclonal antibodies
26. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cnacer that has progressed after chemotherapy for metastatic disease