Fo Shou San, an ancient herbal decoction prepared from Angelicae Sinensis Radix and Chuanxiong Rhizoma, induces erythropoietin expression: A signaling mediated by the reduced degradation of hypoxia-inducible factor in cultured liver cells

Planta Medica

Volumn 78, Issue 2, 2012, Pages 122-127

  Bi, Cathy W C ^a   Xu, Li ^a   Zhang, Wendy L ^a   Zhan, Janis Y X ^a   Fu, Qiang ^a   Zheng, Ken Y Z ^a   Chen, Vicky P ^a   Lau, David T W ^a   Choi, Roy C Y ^a   Wang, Tie J ^a,b   Dong, Tina T X ^a   Tsim, Karl W K ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^b Shenzhen Municipal Institute for Drug Control   (China)

Author keywords

Angelica sinensis; Ligusticum chuanxiong; Umbelliferae

Indexed keywords

ANTIANEMIC AGENT; ERYTHROPOIETIN; FO SHOU SAN; HERBACEOUS AGENT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; UNCLASSIFIED DRUG;

ANGELICAE SINENSIS; ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CHUANXIONG; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ERYTHROPOIESIS; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIVER CELL CARCINOMA; LIVER CELL CULTURE; MEDICINAL PLANT; PLANT ROOT; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RHIZOME;

ANGELICA; CELL LINE, TUMOR; DRUGS, CHINESE HERBAL; ERYTHROPOIETIN; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; LIGUSTICUM; LIVER; PLANT ROOTS; RHIZOME; RNA, MESSENGER; SIGNAL TRANSDUCTION;

ANGELICA SINENSIS; APIACEAE; DANGGUI; LIGUSTICUM CHUANXIONG;

EID: 84856242445     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0031-1280356     Document Type: Article

References (31)

1. Bi C W. C., Xie H Q. H., Xu L, Li J, Cheung A W. H., Zhu J T. T., Zheng Y Z., Chen V P., Law D T. W., Choi R C. Y., Wang T J., Dong T T. X., Tsim K W. K. Fo Shou San, an ancient herbal decoction prepared from Rhizoma Chuanxiong and Radix Angelicae Sinensis, stimulates the production of hemoglobin and erythropoietin in cultured cells. Planta Med 2010 76 1525-1529
2. Gregory C J., Eaves A C. Human marrow cells capable of erythropoietic differentiation in vitro: definition of three erythroid colony responses. Blood 1977 49 855-864 (Pubitemid 8123853)
3. Gregory C J., Eaves A C. Three stages of erythropoietic progenitor cell differentiation distinguished by a number of physical and biologic properties. Blood 1978 51 527-537 (Pubitemid 8298485)
4. Wu H, Lin X, Jaenisch R, Lodish H F. Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell 1995 83 59-67
5. Lin C S., Lim S K., D'Agati V, Costantini F. Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis. Genes Dev 1995 10 154-164
6. Lin F K., Suggs S, Lin C H., Browne J K., Smalling R, Egrie J C., Chen K K., Fox G M., Martin F, Stabinsky Z, Badrawi S M., Lai P H., Goldwasser E. Cloning and expression of the human erythropoietin gene. Proc Natl Acad Sci USA 1985 82 7580-7584 (Pubitemid 16204391)
7. Lai P H., Everett R, Wang F F., Arakawa T, Goldwasser E. Structural characterization of human erythropoietin. J Biol Chem 1986 261 3116-3121 (Pubitemid 17204919)
8. Fukuda M N., Sasaki H, Lopez L, Fukuda M. Survival of recombinant erythropoietin in the circulation: the role of carbohydrates. Blood 1989 73 84-89 (Pubitemid 19040958)
9. Sasaki R, Masuda S, Nagao M. Erythropoietin: multiple physiological functions and regulation of biosynthesis. Biosci Biotechnol Biochem 2000 64 1775-1793
10. Fandrey J. Oxygen-dependent and tissue-specific regulation of erythropoietin gene expression. Am J Physiol Regul Integr Comp Physiol 2004 286 R977-R988 (Pubitemid 38661383)
11. Eckardt K U., Kurtz A. Regulation of erythropoietin production. Eur J Clin Invest 2005 35 13-19 (Pubitemid 41783599)
12. Warnecke C, Zaborowska Z, Kurreck J, Erdmann V A., Frei U, Wiesener M, Eckardt K U. Differentiating the functional role of hypoxia-inducible factor (HIF)-1 and HIF-2 (EPAS-1) by the use of RNA interference. FASEB J 2004 18 1462-1487
13. Goldberg M A., Glass G A., Cunningham J M., Bunn H F. The regulated expression of erythropoietin by two human hepatoma cell lines. Proc Natl Acad Sci USA 1987 84 7972-7976 (Pubitemid 17162815)
14. Haase V H. Hypoxic regulation of erythropoiesis and iron metabolism. Am J Physiol Renal Physiol 2010 299 F1-F13
15. Ebert B L., Bunn H F. Regulation of the erythropoietin gene. Blood 1999 94 1864-1877 (Pubitemid 29430402)
16. Smith T G., Robbins P A., Ratcliffe P J. The human side of hypoxia-inducible factor. Br J Haematol 2008 141 325-334 (Pubitemid 351521147)
17. 2 tension. Proc Natl Sci USA 1995 92 5510-5514
18. 2-regulated prolyl hydroxylation. Science 2001 292 468-472 (Pubitemid 32335942)
19. Ke Q D., Costa M. Hypoxia-inducible factor-1 (HIF-1). Mol Pharmacol 2006 70 1469-1480
20. Gao Q T., Cheung J K. H., Choi R C. Y., Cheung A W. H., Li J, Jiang Z Y., Chu G K. Y., Duan R, Zhao K J., Dong T T. X., Tsim K W. K. A Chinese herbal decoction prepared from Radix Astragali and Radix Angelicae Sinensis induces the expression of erythropoietin in cultured Hep3B cells. Planta Med 2008 74 392-395 (Pubitemid 351578795)
21. Uchimura E, Yamada S, Uebersax L, Fujita S, Miyake M, Miyake J. Method for reverse transfection using gold colloid as a nano-scaffold. J Biosci Bioeng 2007 103 101-103 (Pubitemid 46216910)
22. Metzen E, Ratcliffe P J. HIF hydroxylation and cellular oxygen sensing. Biol Chem 2004 385 223-230 (Pubitemid 38679067)
23. Su Y, Loos M, Giese N, Hines O J., Diebold I, Gorlach A, Metzen E, Pastorekova S, Friess H, Buchler P. PHD3 regulates differentiation, tumour growth and angiogenesis in pancreatic cancer. Br J Cancer 2010 103 1571-1579
24. Shao M L. Pharmacopoeia of the People's Republic of China. (Part I). Beijing Chemical Industry Press 2010 144
25. Liang Q D., Gao Y, Tan H L., Guo P, Li Y F., Zhou Z, Tan W, Ma Z C., Ma B P., Wang S Q. Effects of four Si-Wu-Tang's constituents and their combination on irradiated mice. Biol Pharm Bull 2006 29 1378-1382
26. Lin C M., Chiu J H., Wu I H., Wang B W., Pan C M., Chen Y H. Ferulic acid augments angiogenesis via VEGF, PDGF and HIF-1. J Nutr Biochem 2010 21 627-633
27. Ma Z C., Hong Q, Wang Y G., Tan H L., Xiao C R., Liang Q D., Cai S H., Gao Y. Ferulic acid attenuates adhesion molecule expression in gamma-radiated human umbilical vascular endothelial cells. Biol Pharm Bull 2010 33 752-758
28. Chan S S. K., Cheng T Y., Lin G. Relaxation effects of ligustilide and senkyunolide A, two main constituents of Ligusticum chuanxiong, in rat isolated aorta. J Ethnopharmacol 2007 111 677-680 (Pubitemid 46617091)
29. Park S S., Bae I, Lee Y J. Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1/2 is mediated through chelation of iron. J Cell Biochem 2008 103 1989-1998 (Pubitemid 351501927)
30. Zheng K Y. Z., Guo A J. Y., Bi C W. C., Zhu K Y., Chan G K. L., Fu Q, Xu S L., Zhan J Y. Z., Lau D T. W., Dong T T. X., Choi R C. Y., Tsim K W. K. The extract of Rhodiolae Crenulatae Radix et Rhizoma induces the accumulation of HIF-1 via blocking the degradation pathway in cultured kidney fibroblasts. Planta Med 2011 77 894-899
31. Zheng K Y. Z., Choi R C. Y., Xie H Q. H., Cheung A W. H., Guo A J. Y., Leung K W., Chen V P., Bi C W. C., Zhu K Y., Chan G K. L., Fu Q, Lau D T. W., Dong T T. X., Zhao K J., Tsim K W. K. The expression of erythropoietin triggered by Danggui Buxue Tang, a Chinese herbal decoction prepared from Radix Astragali and Radix Angelicae Sinensis, is mediated by the hypoxia-inducible factor in cultured HEK293T cells. J Ethnopharmacol 2010 132 259-267