The extract of Rhodiolae Crenulatae Radix et Rhizoma induces the accumulation of HIF-1α via blocking the degradation pathway in cultured kidney fibroblasts

Planta Medica

Volumn 77, Issue 9, 2011, Pages 894-899

  Zheng, Ken Y Z ^a   Guo, Ava J Y ^a   Bi, Cathy W C ^a   Zhu, Kevin Y ^a   Chan, Gallant K L ^a   Fu, Qiang ^a   Xu, Sherry L ^a   Zhan, Janis Y Z ^a   Lau, David T W ^a   Dong, Tina T X ^a   Choi, Roy C Y ^a   Tsim, Karl W K ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

Crassulaceae; erythropoietin; hypoxia inducible factor; Rhodiola crenulata (Hook. f. et Thoms.) H. Ohba

Indexed keywords

ERYTHROPOIETIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PLANT EXTRACT; RHODIOLAE CRENULATAE EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DECOMPOSITION; DRUG MECHANISM; FIBROBLAST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; KIDNEY CELL CULTURE; MEDICINAL PLANT; MOLECULAR MECHANICS; PLANT ROOT; PROMOTER REGION; PROTEIN EXPRESSION; RHIZOME; RHODIOLAE CRENULATAE; TRANSCRIPTION INITIATION;

ANOXIA; CELLS, CULTURED; DEFEROXAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; ERYTHROPOIETIN; FIBROBLASTS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KIDNEY; MIXED FUNCTION OXYGENASES; PLANT ROOTS; RECOMBINANT FUSION PROTEINS; RESPONSE ELEMENTS; RHIZOME; RHODIOLA; RNA, MESSENGER; SIDEROPHORES; TRANSCRIPTIONAL ACTIVATION;

CRASSULACEAE; RHODIOLA; RHODIOLA CRENULATA;

EID: 79958854167     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0030-1250627     Document Type: Article

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