-
1
-
-
33645861910
-
Hypoxic pulmonary vasoconstriction: Mechanisms and controversies
-
Aaronson, P.I., Robertson, T.P., Knock, G.A., Becker, S., Lewis, T.H., Snetkov, V. Ward, J.P. (2006) Hypoxic pulmonary vasoconstriction: mechanisms and controversies. Journal of Physiology, 570, 53 58.
-
(2006)
Journal of Physiology
, vol.570
, pp. 53-58
-
-
Aaronson, P.I.1
Robertson, T.P.2
Knock, G.A.3
Becker, S.4
Lewis, T.H.5
Snetkov, V.6
Ward, J.P.7
-
2
-
-
0015256050
-
Plasma erythropoietin in men and mice during acclimatization to different altitudes
-
Abbrecht, P.H. Littell, J.K. (1972) Plasma erythropoietin in men and mice during acclimatization to different altitudes. Journal of Applied Physiology, 32, 54 58.
-
(1972)
Journal of Applied Physiology
, vol.32
, pp. 54-58
-
-
Abbrecht, P.H.1
Littell, J.K.2
-
3
-
-
42049112947
-
Disturbance in the HIF-1α pathway associated with erythrocytosis: Further evidences brought by frameshift and nonsense mutations in the prolyl hydroxylase domain protein 2 (PHD2) gene
-
d.o.i.:
-
Al-Sheikh, M., Moradkhani, K., Lopez, M., Wajcman, H. Prehu, C 2007) Disturbance in the HIF-1α pathway associated with erythrocytosis: further evidences brought by frameshift and nonsense mutations in the prolyl hydroxylase domain protein 2 (PHD2) gene. Blood Cells, Molecules and Diseases. d.o.i.:
-
(2007)
Blood Cells, Molecules and Diseases.
-
-
Al-Sheikh, M.1
Moradkhani, K.2
Lopez, M.3
Wajcman, H.4
Prehu, C.5
-
4
-
-
18744373593
-
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
-
Ang, S., Chen, H., Hirota, K., Gordeuk, V., Jelinek, J., Guan, Y., Liu, E., Sergueeva, A., Miasnikova, G., Mole, D., Maxwell, P., Stockton, D., Semenza, G. Prchal, J. (2002) Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia. Nature Genetics, 32, 614 621.
-
(2002)
Nature Genetics
, vol.32
, pp. 614-621
-
-
Ang, S.1
Chen, H.2
Hirota, K.3
Gordeuk, V.4
Jelinek, J.5
Guan, Y.6
Liu, E.7
Sergueeva, A.8
Miasnikova, G.9
Mole, D.10
Maxwell, P.11
Stockton, D.12
Semenza, G.13
Prchal, J.14
-
5
-
-
0036082090
-
Desferrioxamine elevates pulmonary vascular resistance in humans: Potential for involvement of HIF-1
-
Balanos, G.M., Dorrington, K.L. Robbins, P.A. (2002) Desferrioxamine elevates pulmonary vascular resistance in humans: potential for involvement of HIF-1. Journal of Applied Physiology, 92, 2501 2507.
-
(2002)
Journal of Applied Physiology
, vol.92
, pp. 2501-2507
-
-
Balanos, G.M.1
Dorrington, K.L.2
Robbins, P.A.3
-
6
-
-
0038056173
-
Pulmonary hypertension in chronic obstructive pulmonary disease
-
Barbera, J.A., Peinado, V.I. Santos, S. (2003) Pulmonary hypertension in chronic obstructive pulmonary disease. European Respiratory Journal, 21, 892 905.
-
(2003)
European Respiratory Journal
, vol.21
, pp. 892-905
-
-
Barbera, J.A.1
Peinado, V.I.2
Santos, S.3
-
7
-
-
0041465022
-
HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia
-
Berra, E., Benizri, E., Ginouves, A., Volmat, V., Roux, D. Pouyssegur, J. (2003) HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia. EMBO Journal, 22, 4082 4090.
-
(2003)
EMBO Journal
, vol.22
, pp. 4082-4090
-
-
Berra, E.1
Benizri, E.2
Ginouves, A.3
Volmat, V.4
Roux, D.5
Pouyssegur, J.6
-
8
-
-
85047691081
-
Heterozygous deficiency of hypoxia-inducible factor-2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia
-
Brusselmans, K., Compernolle, V., Tjwa, M., Wiesener, M.S., Maxwell, P.H., Collen, D. Carmeliet, P. (2003) Heterozygous deficiency of hypoxia-inducible factor-2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia. Journal of Clinical Investigation, 111, 1519 1527.
-
(2003)
Journal of Clinical Investigation
, vol.111
, pp. 1519-1527
-
-
Brusselmans, K.1
Compernolle, V.2
Tjwa, M.3
Wiesener, M.S.4
Maxwell, P.H.5
Collen, D.6
Carmeliet, P.7
-
9
-
-
33745756977
-
Endothelin-1, vascular endothelial growth factor and systolic pulmonary artery pressure in patients with Chuvash polycythemia
-
Bushuev, V.I., Miasnikova, G.Y., Sergueeva, A.I., Polyakova, L.A., Okhotin, D., Gaskin, P.R., Debebe, Z., Nekhai, S., Castro, O.L., Prchal, J.T. Gordeuk, V.R. (2006) Endothelin-1, vascular endothelial growth factor and systolic pulmonary artery pressure in patients with Chuvash polycythemia. Haematologica, 91, 744 749.
-
(2006)
Haematologica
, vol.91
, pp. 744-749
-
-
Bushuev, V.I.1
Miasnikova, G.Y.2
Sergueeva, A.I.3
Polyakova, L.A.4
Okhotin, D.5
Gaskin, P.R.6
Debebe, Z.7
Nekhai, S.8
Castro, O.L.9
Prchal, J.T.10
Gordeuk, V.R.11
-
10
-
-
25144457125
-
Transcriptional repression of human cad gene by hypoxia inducible factor-1α
-
Chen, K.F., Lai, Y.Y., Sun, H.S. Tsai, S.J. (2005) Transcriptional repression of human cad gene by hypoxia inducible factor-1α. Nucleic Acids Research, 33, 5190 5198.
-
(2005)
Nucleic Acids Research
, vol.33
, pp. 5190-5198
-
-
Chen, K.F.1
Lai, Y.Y.2
Sun, H.S.3
Tsai, S.J.4
-
11
-
-
0034682783
-
Hypoxia inducible factor-α binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
-
Cockman, M.E., Masson, N., Mole, D.R., Jaakkola, P., Chang, G.W., Clifford, S.C., Maher, E.R., Pugh, C.W., Ratcliffe, P.J. Maxwell, P.H. (2000) Hypoxia inducible factor-α binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein. Journal of Biological Chemistry, 275, 25733 25741.
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 25733-25741
-
-
Cockman, M.E.1
Masson, N.2
Mole, D.R.3
Jaakkola, P.4
Chang, G.W.5
Clifford, S.C.6
Maher, E.R.7
Pugh, C.W.8
Ratcliffe, P.J.9
Maxwell, P.H.10
-
12
-
-
8644224030
-
Human pulmonary vascular responses to hypoxia and hypercapnia
-
Dorrington, K.L. Talbot, N.P. (2004) Human pulmonary vascular responses to hypoxia and hypercapnia. Pflügers Archive, 449, 1 15.
-
(2004)
Pflügers Archive
, vol.449
, pp. 1-15
-
-
Dorrington, K.L.1
Talbot, N.P.2
-
13
-
-
33751261878
-
Time-course of the human pulmonary vascular response to 8 hours of isocapnic hypoxia
-
Dorrington, K.L., Clar, C., Young, J.D., Jonas, M., Tansley, J.G. Robbins, P.A. (1997) Time-course of the human pulmonary vascular response to 8 hours of isocapnic hypoxia. American Journal of Physiology, 273, H1126 H1134.
-
(1997)
American Journal of Physiology
, vol.273
-
-
Dorrington, K.L.1
Clar, C.2
Young, J.D.3
Jonas, M.4
Tansley, J.G.5
Robbins, P.A.6
-
14
-
-
0000625749
-
Physiological observations made on Pike's Peak, Colorado, with special reference to adaptation to low barometric pressure
-
Douglas, C.G., Haldane, J.S., Henderson, Y. Schneider, E.C. (1913) Physiological observations made on Pike's Peak, Colorado, with special reference to adaptation to low barometric pressure. Philosophical Transactions of the Royal Society B, 203, 185 318.
-
(1913)
Philosophical Transactions of the Royal Society B
, vol.203
, pp. 185-318
-
-
Douglas, C.G.1
Haldane, J.S.2
Henderson, Y.3
Schneider, E.C.4
-
15
-
-
0024604624
-
Rate of erythropoietin formation in humans in response to acute hypobaric hypoxia
-
Eckardt, K.U., Boutellier, U., Kurtz, A., Schopen, M., Koller, E.A. Bauer, C. (1989) Rate of erythropoietin formation in humans in response to acute hypobaric hypoxia. Journal of Applied Physiology, 66, 1785 1788.
-
(1989)
Journal of Applied Physiology
, vol.66
, pp. 1785-1788
-
-
Eckardt, K.U.1
Boutellier, U.2
Kurtz, A.3
Schopen, M.4
Koller, E.A.5
Bauer, C.6
-
16
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
Epstein, A., Gleadle, J., McNeill, L., Hewitson, K., O'Rourke, J., Mole, D., Mukherji, M., Metzen, E., Wilson, M., Dhanda, A., Tian, Y., Masson, N., Hamilton, D., Jaakkola, P., Barstead, R., Hodgkin, J., Maxwell, P., Pugh, C., Schofield, C. Ratcliffe, P. (2001) C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell, 107, 43 54.
-
(2001)
Cell
, vol.107
, pp. 43-54
-
-
Epstein, A.1
Gleadle, J.2
McNeill, L.3
Hewitson, K.4
O'Rourke, J.5
Mole, D.6
Mukherji, M.7
Metzen, E.8
Wilson, M.9
Dhanda, A.10
Tian, Y.11
Masson, N.12
Hamilton, D.13
Jaakkola, P.14
Barstead, R.15
Hodgkin, J.16
Maxwell, P.17
Pugh, C.18
Schofield, C.19
Ratcliffe, P.20
more..
-
17
-
-
0000009635
-
Humoral regulation of red cell production
-
Erslev, A. (1953) Humoral regulation of red cell production. Blood, 8, 349 357.
-
(1953)
Blood
, vol.8
, pp. 349-357
-
-
Erslev, A.1
-
18
-
-
0028359320
-
Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase a genes: Similarities with the erythropoietin 3′ enhancer
-
Firth, J.D., Ebert, B.L., Pugh, C.W. Ratcliffe, P.J. (1994) Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3′ enhancer. Proceedings of the National Academy of Sciences U S A, 91, 6496 6500.
-
(1994)
Proceedings of the National Academy of Sciences U S a
, vol.91
, pp. 6496-6500
-
-
Firth, J.D.1
Ebert, B.L.2
Pugh, C.W.3
Ratcliffe, P.J.4
-
20
-
-
0027324745
-
Expression of endothelin-1 in the lungs of patients with pulmonary hypertension
-
Giaid, A., Yanagisawa, M., Langleben, D., Michel, R.P., Levy, R., Shennib, H., Kimura, S., Masaki, T., Duguid, W.P. Stewart, D.J. (1993) Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. New England Journal of Medicine, 328, 1732 1739.
-
(1993)
New England Journal of Medicine
, vol.328
, pp. 1732-1739
-
-
Giaid, A.1
Yanagisawa, M.2
Langleben, D.3
Michel, R.P.4
Levy, R.5
Shennib, H.6
Kimura, S.7
Masaki, T.8
Duguid, W.P.9
Stewart, D.J.10
-
21
-
-
2342631195
-
Congenital disorder of oxygen sensing: Association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors
-
Gordeuk, V.R., Sergueeva, A.I., Miasnikova, G.Y., Okhotin, D., Voloshin, Y., Choyke, P.L., Butman, J.A., Jedlickova, K., Prchal, J.T. Polyakova, L.A. (2004) Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors. Blood, 103, 3924 3932.
-
(2004)
Blood
, vol.103
, pp. 3924-3932
-
-
Gordeuk, V.R.1
Sergueeva, A.I.2
Miasnikova, G.Y.3
Okhotin, D.4
Voloshin, Y.5
Choyke, P.L.6
Butman, J.A.7
Jedlickova, K.8
Prchal, J.T.9
Polyakova, L.A.10
-
22
-
-
13244275298
-
Congenital polycythemias/erythrocytoses
-
Gordeuk, V.R., Stockton, D.W. Prchal, J.T. (2005) Congenital polycythemias/erythrocytoses. Haematologica, 90, 109 116.
-
(2005)
Haematologica
, vol.90
, pp. 109-116
-
-
Gordeuk, V.R.1
Stockton, D.W.2
Prchal, J.T.3
-
23
-
-
0003028645
-
Physiological variariations of the cardiac output of man. VII. the effect of high altitude and its related functions: An account of experiments conducted on the summit of Pikes Peaks, Colorado
-
Grollman, A. (1930) Physiological variariations of the cardiac output of man. VII. The effect of high altitude and its related functions: an account of experiments conducted on the summit of Pikes Peaks, Colorado. American Journal of Physiology, 93, 19 40.
-
(1930)
American Journal of Physiology
, vol.93
, pp. 19-40
-
-
Grollman, A.1
-
24
-
-
0027477952
-
Minimal hypoxic pulmonary hypertension in normal Tibetans at 3,658 m
-
Groves, B.M., Droma, T., Sutton, J.R., McCullough, R.G., McCullough, R.E., Zhuang, J., Rapmund, G., Sun, S., James, C. Moore, L.G. (1993) Minimal hypoxic pulmonary hypertension in normal Tibetans at 3,658 m. Journal of Applied Physiology, 74, 312 318.
-
(1993)
Journal of Applied Physiology
, vol.74
, pp. 312-318
-
-
Groves, B.M.1
Droma, T.2
Sutton, J.R.3
McCullough, R.G.4
McCullough, R.E.5
Zhuang, J.6
Rapmund, G.7
Sun, S.8
James, C.9
Moore, L.G.10
-
25
-
-
0031733828
-
Molecular characterization and chromosomal localization of a third α-class hypoxia inducible factor subunit, HIF3α
-
Gu, Y.Z., Moran, S.M., Hogenesch, J.B., Wartman, L. Bradfield, C.A. (1998) Molecular characterization and chromosomal localization of a third α-class hypoxia inducible factor subunit, HIF3α. Gene Expression, 7, 205 213.
-
(1998)
Gene Expression
, vol.7
, pp. 205-213
-
-
Gu, Y.Z.1
Moran, S.M.2
Hogenesch, J.B.3
Wartman, L.4
Bradfield, C.A.5
-
28
-
-
18544386401
-
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family
-
Hewitson, K.S., McNeill, L.A., Riordan, M.V., Tian, Y.M., Bullock, A.N., Welford, R.W., Elkins, J.M., Oldham, N.J., Bhattacharya, S., Gleadle, J.M., Ratcliffe, P.J., Pugh, C.W. Schofield, C.J. (2002) Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family. Journal of Biological Chemistry, 277, 26351 26355.
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 26351-26355
-
-
Hewitson, K.S.1
McNeill, L.A.2
Riordan, M.V.3
Tian, Y.M.4
Bullock, A.N.5
Welford, R.W.6
Elkins, J.M.7
Oldham, N.J.8
Bhattacharya, S.9
Gleadle, J.M.10
Ratcliffe, P.J.11
Pugh, C.W.12
Schofield, C.J.13
-
30
-
-
0016693657
-
Normal values for hypoxic and hypercapnic ventilatory drives in man
-
Hirshman, C.A., McCullough, R.E. Weil, J.V. (1975) Normal values for hypoxic and hypercapnic ventilatory drives in man. Journal of Applied Physiology, 38, 1095 1098.
-
(1975)
Journal of Applied Physiology
, vol.38
, pp. 1095-1098
-
-
Hirshman, C.A.1
McCullough, R.E.2
Weil, J.V.3
-
31
-
-
0043234538
-
Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor
-
Hirsila, M., Koivunen, P., Gunzler, V., Kivirikko, K.I. Myllyharju, J. (2003) Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor. Journal of Biological Chemistry, 278, 30772 30780.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 30772-30780
-
-
Hirsila, M.1
Koivunen, P.2
Gunzler, V.3
Kivirikko, K.I.4
Myllyharju, J.5
-
32
-
-
0029753008
-
Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit
-
Huang, L.E., Arany, Z., Livingston, D.M. Bunn, H.F. (1996) Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit. Journal of Biological Chemistry, 271, 32253 32259.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 32253-32259
-
-
Huang, L.E.1
Arany, Z.2
Livingston, D.M.3
Bunn, H.F.4
-
34
-
-
0035917313
-
2 sensing
-
2 sensing. Science, 292, 464 468.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin, W.G.10
-
35
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
2-regulated prolyl hydroxylation. Science, 292, 468 472.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.-M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Kriegsheim, A.V.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
36
-
-
0029944965
-
Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1
-
Jiang, B.H., Rue, E., Wang, G.L., Roe, R. Semenza, G.L. (1996) Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1. Journal of Biological Chemistry, 271, 17771 17778.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 17771-17778
-
-
Jiang, B.H.1
Rue, E.2
Wang, G.L.3
Roe, R.4
Semenza, G.L.5
-
37
-
-
0037154262
-
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
-
Kline, D.D., Peng, Y.-J., Manalo, D.J., Semenza, G.L. Prabhakar, N.R. (2002) Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α. Proceedings of the National Academy of Sciences U S A, 99, 821 826.
-
(2002)
Proceedings of the National Academy of Sciences U S a
, vol.99
, pp. 821-826
-
-
Kline, D.D.1
Peng, Y.-J.2
Manalo, D.J.3
Semenza, G.L.4
Prabhakar, N.R.5
-
38
-
-
0037446983
-
Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells
-
Knowles, H.J., Raval, R.R., Harris, A.L. Ratcliffe, P.J. (2003) Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells. Cancer Research, 63, 1764 1768.
-
(2003)
Cancer Research
, vol.63
, pp. 1764-1768
-
-
Knowles, H.J.1
Raval, R.R.2
Harris, A.L.3
Ratcliffe, P.J.4
-
39
-
-
0036469038
-
Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch
-
Lando, D., Peet, D.J., Whelan, D.A., Gorman, J.J. Whitelaw, M.L. (2002) Asparagine hydroxylation of the HIF transactivation domain: a hypoxic switch. Science, 295, 858 861.
-
(2002)
Science
, vol.295
, pp. 858-861
-
-
Lando, D.1
Peet, D.J.2
Whelan, D.A.3
Gorman, J.J.4
Whitelaw, M.L.5
-
40
-
-
34247211079
-
Association of polymorphisms of 1772 (C - >t) and 1790 (G - >a) in HIF1A gene with hypoxia adaptation in high altitude in Sherpas
-
Liu, K.X., Sun, X.C., Wang, S.W. Hu, B. (2007) Association of polymorphisms of 1772 (C - >T) and 1790 (G - >A) in HIF1A gene with hypoxia adaptation in high altitude in Sherpas. Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 24, 230 232.
-
(2007)
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
, vol.24
, pp. 230-232
-
-
Liu, K.X.1
Sun, X.C.2
Wang, S.W.3
Hu, B.4
-
41
-
-
0000655498
-
Identification of a hypoxia response element in the transferrin receptor gene
-
Lok, C.N. Ponka, P. (1999) Identification of a hypoxia response element in the transferrin receptor gene. Journal of Biological Chemistry, 274, 24147 24152.
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 24147-24152
-
-
Lok, C.N.1
Ponka, P.2
-
42
-
-
0037709883
-
Von Hippel-Lindau disease
-
Lonser, R.R., Glenn, G.M., Walther, M., Chew, E.Y., Libutti, S.K., Linehan, W.M. Oldfield, E.H. (2003) von Hippel-Lindau disease. Lancet, 361, 2059 2067.
-
(2003)
Lancet
, vol.361
, pp. 2059-2067
-
-
Lonser, R.R.1
Glenn, G.M.2
Walther, M.3
Chew, E.Y.4
Libutti, S.K.5
Linehan, W.M.6
Oldfield, E.H.7
-
43
-
-
0027461553
-
Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: Evidence for a widespread oxygen-sensing mechanism
-
Maxwell, P.H., Pugh, C.W. Ratcliffe, P.J. (1993) Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism. Proceedings of the National Academy of Sciences USA, 90, 2423 2427.
-
(1993)
Proceedings of the National Academy of Sciences USA
, vol.90
, pp. 2423-2427
-
-
Maxwell, P.H.1
Pugh, C.W.2
Ratcliffe, P.J.3
-
44
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell, P., Wiesener, M., Chang, G., Clifford, S., Vaux, E., Cockman, M., Wykoff, C., Pugh, C., Maher, E. Ratcliffe, P. (1999) The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature, 399, 271 275.
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.1
Wiesener, M.2
Chang, G.3
Clifford, S.4
Vaux, E.5
Cockman, M.6
Wykoff, C.7
Pugh, C.8
Maher, E.9
Ratcliffe, P.10
-
45
-
-
13244273759
-
Genetic association analysis of chronic mountain sickness in an Andean high-altitude population
-
Mejia, O.M., Prchal, J.T., Leon-Velarde, F., Hurtado, A. Stockton, D.W. (2005) Genetic association analysis of chronic mountain sickness in an Andean high-altitude population. Haematologica, 90, 13 19.
-
(2005)
Haematologica
, vol.90
, pp. 13-19
-
-
Mejia, O.M.1
Prchal, J.T.2
Leon-Velarde, F.3
Hurtado, A.4
Stockton, D.W.5
-
46
-
-
0022253153
-
Serum erythropoietin in humans at high altitude and its relation to plasma renin
-
Milledge, J.S. Cotes, P.M. (1985) Serum erythropoietin in humans at high altitude and its relation to plasma renin. Journal of Applied Physiology, 59, 360 364.
-
(1985)
Journal of Applied Physiology
, vol.59
, pp. 360-364
-
-
Milledge, J.S.1
Cotes, P.M.2
-
47
-
-
0000707862
-
The influence of short periods of acute anoxia upon pulmonary arterial pressures in man
-
Motley, H.L., Cournand, A., Werko, L., Himmelstein, A. Dresdale, D. (1947) The influence of short periods of acute anoxia upon pulmonary arterial pressures in man. American Journal of Physiology, 150, 315 320.
-
(1947)
American Journal of Physiology
, vol.150
, pp. 315-320
-
-
Motley, H.L.1
Cournand, A.2
Werko, L.3
Himmelstein, A.4
Dresdale, D.5
-
48
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth, E., Tuttle, M.S., Powelson, J., Vaughn, M.B., Donovan, A., Ward, D.M., Ganz, T. Kaplan, J. (2004) Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science, 306, 2090 2093.
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
Vaughn, M.B.4
Donovan, A.5
Ward, D.M.6
Ganz, T.7
Kaplan, J.8
-
49
-
-
34147202137
-
Desferrioxamine enhances hypoxic ventilatory response and induces tyrosine hydroxylase gene expression in the rat brainstem in vivo
-
Nguyen, M.V., Pouvreau, S., El Hajjaji, F.Z., Denavit-Saubie, M. Pequignot, J.M. (2007) Desferrioxamine enhances hypoxic ventilatory response and induces tyrosine hydroxylase gene expression in the rat brainstem in vivo. Journal of Neuroscience Research, 85, 1119 1125.
-
(2007)
Journal of Neuroscience Research
, vol.85
, pp. 1119-1125
-
-
Nguyen, M.V.1
Pouvreau, S.2
El Hajjaji, F.Z.3
Denavit-Saubie, M.4
Pequignot, J.M.5
-
50
-
-
0033776536
-
Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein
-
Ohh, M., Park, C.W., Ivan, M., Hoffman, M.A., Kim, T.Y., Huang, L.E., Pavletich, N., Chau, V. Kaelin, W.G. (2000) Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. Nature Cell Biology, 2, 423 427.
-
(2000)
Nature Cell Biology
, vol.2
, pp. 423-427
-
-
Ohh, M.1
Park, C.W.2
Ivan, M.3
Hoffman, M.A.4
Kim, T.Y.5
Huang, L.E.6
Pavletich, N.7
Chau, V.8
Kaelin, W.G.9
-
51
-
-
33846870322
-
Role of hypoxia-inducible factor-1α as a cancer therapy target
-
Patiar, S. Harris, A.L. (2006) Role of hypoxia-inducible factor-1α as a cancer therapy target. Endocrine-Related Cancer, 13, S61 S75.
-
(2006)
Endocrine-Related Cancer
, vol.13
-
-
Patiar, S.1
Harris, A.L.2
-
52
-
-
33947606593
-
The heart and pulmonary circulation at high altitudes: Healthy highlanders and chronic mountain sickness
-
Penaloza, D. Arias-Stella, J. (2007) The heart and pulmonary circulation at high altitudes: healthy highlanders and chronic mountain sickness. Circulation, 115, 1132 1146.
-
(2007)
Circulation
, vol.115
, pp. 1132-1146
-
-
Penaloza, D.1
Arias-Stella, J.2
-
53
-
-
33751329032
-
Heterozygous HIF-1α deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia
-
Peng, Y.J., Yuan, G., Ramakrishnan, D., Sharma, S.D., Bosch-Marce, M., Kumar, G.K., Semenza, G.L. Prabhakar, N.R. (2006) Heterozygous HIF-1α deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia. Journal of Physiology, 577, 705 716.
-
(2006)
Journal of Physiology
, vol.577
, pp. 705-716
-
-
Peng, Y.J.1
Yuan, G.2
Ramakrishnan, D.3
Sharma, S.D.4
Bosch-Marce, M.5
Kumar, G.K.6
Semenza, G.L.7
Prabhakar, N.R.8
-
54
-
-
34247212833
-
Genetically heterogeneous origins of idiopathic erythrocytosis
-
Percy, M.L. (2007) Genetically heterogeneous origins of idiopathic erythrocytosis. Hematology, 12, 131 139.
-
(2007)
Hematology
, vol.12
, pp. 131-139
-
-
Percy, M.L.1
-
55
-
-
31444436640
-
A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis
-
Percy, M.J., Zhao, Q., Flores, A., Harrison, C., Lappin, T.R., Maxwell, P.H., McMullin, M.F. Lee, F.S. (2006) A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis. Proceedings of the National Academy of Sciences USA, 103, 654 659.
-
(2006)
Proceedings of the National Academy of Sciences USA
, vol.103
, pp. 654-659
-
-
Percy, M.J.1
Zhao, Q.2
Flores, A.3
Harrison, C.4
Lappin, T.R.5
Maxwell, P.H.6
McMullin, M.F.7
Lee, F.S.8
-
56
-
-
34548848799
-
A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove
-
Percy, M.J., Furlow, P.W., Beer, P.A., Lappin, T.R., McMullin, M.F. Lee, F.S. (2007) A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove. Blood, 110, 2193 2196.
-
(2007)
Blood
, vol.110
, pp. 2193-2196
-
-
Percy, M.J.1
Furlow, P.W.2
Beer, P.A.3
Lappin, T.R.4
McMullin, M.F.5
Lee, F.S.6
-
57
-
-
30444459356
-
Von Hippel-Lindau-dependent polycythemia is endemic on the island of Ischia: Identification of a novel cluster
-
Perrotta, S., Nobili, B., Ferraro, M., Migliaccio, C., Borriello, A., Cucciolla, V., Martinelli, V., Rossi, F., Punzo, F., Cirillo, P., Parisi, G., Zappia, V., Rotoli, B. Ragione, F.D. (2006) von Hippel-Lindau-dependent polycythemia is endemic on the island of Ischia: identification of a novel cluster. Blood, 107, 514 519.
-
(2006)
Blood
, vol.107
, pp. 514-519
-
-
Perrotta, S.1
Nobili, B.2
Ferraro, M.3
Migliaccio, C.4
Borriello, A.5
Cucciolla, V.6
Martinelli, V.7
Rossi, F.8
Punzo, F.9
Cirillo, P.10
Parisi, G.11
Zappia, V.12
Rotoli, B.13
Ragione, F.D.14
-
58
-
-
34447120059
-
Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)
-
Peyssonnaux, C., Zinkernagel, A.S., Schuepbach, R.A., Rankin, E., Vaulont, S., Haase, V.H., Nizet, V. Johnson, R.S. (2007) Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). Journal of Clinical Investigation, 117, 1926 1932.
-
(2007)
Journal of Clinical Investigation
, vol.117
, pp. 1926-1932
-
-
Peyssonnaux, C.1
Zinkernagel, A.S.2
Schuepbach, R.A.3
Rankin, E.4
Vaulont, S.5
Haase, V.H.6
Nizet, V.7
Johnson, R.S.8
-
59
-
-
0016118725
-
Familial erythrocytosis among the residents of the Chuvash ASSR
-
Polyakova, L.A. (1974) Familial erythrocytosis among the residents of the Chuvash ASSR. Problemy Gematologii i Perelivaniia Krovi, 19, 30 33.
-
(1974)
Problemy Gematologii I Perelivaniia Krovi
, vol.19
, pp. 30-33
-
-
Polyakova, L.A.1
-
60
-
-
0345871948
-
Sequence variation in hypoxia-inducible factor 1α (HIF1A): Association with maximal oxygen consumption
-
Prior, S.J., Hagberg, J.M., Phares, D.A., Brown, M.D., Fairfull, L., Ferrell, R.E. Roth, S.M. (2003) Sequence variation in hypoxia-inducible factor 1α (HIF1A): association with maximal oxygen consumption. Physiological Genomics, 15, 20 26.
-
(2003)
Physiological Genomics
, vol.15
, pp. 20-26
-
-
Prior, S.J.1
Hagberg, J.M.2
Phares, D.A.3
Brown, M.D.4
Fairfull, L.5
Ferrell, R.E.6
Roth, S.M.7
-
61
-
-
0030937718
-
Activation of hypoxia-inducible factor-1; Definition of regulatory domains within the α subunit
-
Pugh, C.W., O'Rourke, J.F., Nagao, M., Gleadle, J.M. Ratcliffe, P.J. (1997) Activation of hypoxia-inducible factor-1; definition of regulatory domains within the α subunit. Journal of Biological Chemistry, 272, 11205 11214.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 11205-11214
-
-
Pugh, C.W.1
O'Rourke, J.F.2
Nagao, M.3
Gleadle, J.M.4
Ratcliffe, P.J.5
-
62
-
-
0000232970
-
Man's respiratory response during and after acclimatization to high altitude
-
Rahn, H. Otis, A.B. (1949) Man's respiratory response during and after acclimatization to high altitude. American Journal of Physiology, 157, 445 462.
-
(1949)
American Journal of Physiology
, vol.157
, pp. 445-462
-
-
Rahn, H.1
Otis, A.B.2
-
63
-
-
34147124264
-
Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo
-
Rankin, E.B., Biju, M.P., Liu, Q., Unger, T.L., Rha, J., Johnson, R.S., Simon, M.C., Keith, B. Haase, V.H. (2007) Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo. Journal of Clinical Investigation, 117, 1068 1077.
-
(2007)
Journal of Clinical Investigation
, vol.117
, pp. 1068-1077
-
-
Rankin, E.B.1
Biju, M.P.2
Liu, Q.3
Unger, T.L.4
Rha, J.5
Johnson, R.S.6
Simon, M.C.7
Keith, B.8
Haase, V.H.9
-
64
-
-
0033894551
-
Effects of desferrioxamine on serum erythropoietin and ventilatory sensitivity to hypoxia in humans
-
Ren, X., Dorrington, K.L., Maxwell, P.H. Robbins, P.A. (2000) Effects of desferrioxamine on serum erythropoietin and ventilatory sensitivity to hypoxia in humans. Journal of Applied Physiology, 89, 680 686.
-
(2000)
Journal of Applied Physiology
, vol.89
, pp. 680-686
-
-
Ren, X.1
Dorrington, K.L.2
Maxwell, P.H.3
Robbins, P.A.4
-
66
-
-
0000093975
-
The polycythemia of high altitudes: Iron metabolism and related aspects
-
Reynafarje, C., Lozano, R. Valdivieso, J. (1959) The polycythemia of high altitudes: iron metabolism and related aspects. Blood, 14, 433 455.
-
(1959)
Blood
, vol.14
, pp. 433-455
-
-
Reynafarje, C.1
Lozano, R.2
Valdivieso, J.3
-
67
-
-
0028293145
-
Control of erythropoiesis in humans during prolonged exposure to the altitude of 6,542 m
-
Richalet, J.P., Souberbielle, J.C., Antezana, A.M., Dechaux, M., Le Trong, J.L., Bienvenu, A., Daniel, F., Blanchot, C. Zittoun, J. (1994) Control of erythropoiesis in humans during prolonged exposure to the altitude of 6,542 m. American Journal of Physiology, 266, R756 R764.
-
(1994)
American Journal of Physiology
, vol.266
-
-
Richalet, J.P.1
Souberbielle, J.C.2
Antezana, A.M.3
Dechaux, M.4
Le Trong, J.L.5
Bienvenu, A.6
Daniel, F.7
Blanchot, C.8
Zittoun, J.9
-
68
-
-
34548691285
-
Role of the peripheral chemoreflex in the early stages of ventilatory acclimatization to altitude
-
Robbins, P.A. (2007) Role of the peripheral chemoreflex in the early stages of ventilatory acclimatization to altitude. Respiratory Physiology and Neurobiology, 158, 237 242.
-
(2007)
Respiratory Physiology and Neurobiology
, vol.158
, pp. 237-242
-
-
Robbins, P.A.1
-
69
-
-
0030792094
-
Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1
-
Rolfs, A., Kvietikova, I., Gassmann, M. Wenger, R.H. (1997) Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1. Journal of Biological Chemistry, 272, 20055 20062.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 20055-20062
-
-
Rolfs, A.1
Kvietikova, I.2
Gassmann, M.3
Wenger, R.H.4
-
70
-
-
0030961006
-
Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
-
Salceda, S. Caro, J. (1997) Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. Journal of Biological Chemistry, 272, 22642 22647.
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 22642-22647
-
-
Salceda, S.1
Caro, J.2
-
71
-
-
34247628002
-
Iron-regulatory proteins limit hypoxia-inducible factor-2α expression in iron deficiency
-
Sanchez, M., Galy, B., Muckenthaler, M.U. Hentze, M.W. (2007) Iron-regulatory proteins limit hypoxia-inducible factor-2α expression in iron deficiency. Nature Structural and Molecular Biology, 14, 420 426.
-
(2007)
Nature Structural and Molecular Biology
, vol.14
, pp. 420-426
-
-
Sanchez, M.1
Galy, B.2
Muckenthaler, M.U.3
Hentze, M.W.4
-
72
-
-
0026638065
-
Augmented hypoxic ventilatory response in men at altitude
-
Sato, M., Severinghaus, J.W., Powell, F.L., Xu, F.-D. Spellman, M.J. (1992) Augmented hypoxic ventilatory response in men at altitude. Journal of Applied Physiology, 73, 101 107.
-
(1992)
Journal of Applied Physiology
, vol.73
, pp. 101-107
-
-
Sato, M.1
Severinghaus, J.W.2
Powell, F.L.3
Xu, F.-D.4
Spellman, M.J.5
-
74
-
-
8344237449
-
Hydroxylation of HIF-1: Oxygen sensing at the molecular level
-
Semenza, G.L. (2004) Hydroxylation of HIF-1: oxygen sensing at the molecular level. Physiology (Bethesda), 19, 176 182.
-
(2004)
Physiology (Bethesda)
, vol.19
, pp. 176-182
-
-
Semenza, G.L.1
-
75
-
-
33645786505
-
Development of novel therapeutic strategies that target HIF-1
-
Semenza, G.L. (2006) Development of novel therapeutic strategies that target HIF-1. Expert Opinion on Therapeutic Targets, 10, 267 280.
-
(2006)
Expert Opinion on Therapeutic Targets
, vol.10
, pp. 267-280
-
-
Semenza, G.L.1
-
76
-
-
0026468180
-
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
-
Semenza, G. Wang, G. (1992) A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Molecular and Cellular Biology, 12, 5447 5454.
-
(1992)
Molecular and Cellular Biology
, vol.12
, pp. 5447-5454
-
-
Semenza, G.1
Wang, G.2
-
77
-
-
0030460724
-
Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase a gene promoters contain essential binding sites for hypoxia-inducible factor 1
-
Semenza, G.L., Jiang, B.H., Leung, S.W., Passantino, R., Concordet, J.P., Maire, P. Giallongo, A. (1996) Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. Journal of Biological Chemistry, 271, 32529 32537.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 32529-32537
-
-
Semenza, G.L.1
Jiang, B.H.2
Leung, S.W.3
Passantino, R.4
Concordet, J.P.5
Maire, P.6
Giallongo, A.7
-
78
-
-
0030985635
-
Congenital polycythemia in Chuvashia
-
Sergeyeva, A., Gordeuk, V.R., Tokarev, Y.N., Sokol, L., Prchal, J.F. Prchal, J.T. (1997) Congenital polycythemia in Chuvashia. Blood, 89, 2148 2154.
-
(1997)
Blood
, vol.89
, pp. 2148-2154
-
-
Sergeyeva, A.1
Gordeuk, V.R.2
Tokarev, Y.N.3
Sokol, L.4
Prchal, J.F.5
Prchal, J.T.6
-
79
-
-
0034815688
-
Partial HIF-1α deficiency impairs pulmonary arterial myocyte electrophysiological responses to hypoxia
-
Shimoda, L.A., Manalo, D.J., Sham, J.S.K., Semenza, G.L. Sylvester, J.T. (2001) Partial HIF-1α deficiency impairs pulmonary arterial myocyte electrophysiological responses to hypoxia. American Journal of Physiology - Lung Cellular and Molecular Physiology, 281, L202 L208.
-
(2001)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.281
-
-
Shimoda, L.A.1
Manalo, D.J.2
Sham, J.S.K.3
Semenza, G.L.4
Sylvester, J.T.5
-
80
-
-
35948972354
-
Iron, pre-eclampsia and hypoxia-inducible factor
-
Smith, T.G. Robbins, P.A. (2007) Iron, pre-eclampsia and hypoxia-inducible factor. BJOG, 114, 1581 1582.
-
(2007)
BJOG
, vol.114
, pp. 1581-1582
-
-
Smith, T.G.1
Robbins, P.A.2
-
81
-
-
33746398489
-
Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology
-
Smith, T.G., Brooks, J.T., Balanos, G.M., Lappin, T.R., Layton, D.M., Leedham, D.L., Liu, C., Maxwell, P.H., McMullin, M.F., McNamara, C.J., Percy, M.J., Pugh, C.W., Ratcliffe, P.J., Talbot, N.P., Treacy, M. Robbins, P.A. (2006) Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology. PLoS Medicine, 3, 1178 1185.
-
(2006)
PLoS Medicine
, vol.3
, pp. 1178-1185
-
-
Smith, T.G.1
Brooks, J.T.2
Balanos, G.M.3
Lappin, T.R.4
Layton, D.M.5
Leedham, D.L.6
Liu, C.7
Maxwell, P.H.8
McMullin, M.F.9
McNamara, C.J.10
Percy, M.J.11
Pugh, C.W.12
Ratcliffe, P.J.13
Talbot, N.P.14
Treacy, M.15
Robbins, P.A.16
-
82
-
-
5644240828
-
Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (HIF) in regulating HIF transcriptional target genes
-
Stolze, I.P., Tian, Y.M., Appelhoff, R.J., Turley, H., Wykoff, C.C., Gleadle, J.M. Ratcliffe, P.J. (2004) Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (HIF) in regulating HIF transcriptional target genes. Journal of Biological Chemistry, 279, 42719 42725.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 42719-42725
-
-
Stolze, I.P.1
Tian, Y.M.2
Appelhoff, R.J.3
Turley, H.4
Wykoff, C.C.5
Gleadle, J.M.6
Ratcliffe, P.J.7
-
83
-
-
0033588021
-
Transferrin receptor induction by hypoxia. HIF-1-mediated transcriptional activation and cell-specific post-transcriptional regulation
-
Tacchini, L., Bianchi, L., Bernelli-Zazzera, A. Cairo, G. (1999) Transferrin receptor induction by hypoxia. HIF-1-mediated transcriptional activation and cell-specific post-transcriptional regulation. Journal of Biological Chemistry, 274, 24142 24146.
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 24142-24146
-
-
Tacchini, L.1
Bianchi, L.2
Bernelli-Zazzera, A.3
Cairo, G.4
-
84
-
-
14144253561
-
Two temporal components within the human pulmonary vascular response to ∼2 h of isocapnic hypoxia
-
Talbot, N.P., Balanos, G.M., Dorrington, K.L. Robbins, P.A. (2005) Two temporal components within the human pulmonary vascular response to ∼2 h of isocapnic hypoxia. Journal of Applied Physiology, 98, 1125 1139.
-
(2005)
Journal of Applied Physiology
, vol.98
, pp. 1125-1139
-
-
Talbot, N.P.1
Balanos, G.M.2
Dorrington, K.L.3
Robbins, P.A.4
-
85
-
-
0031020884
-
Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
-
Tian, H., McKnight, S. Russell, D. (1997) Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes and Development, 11, 72 82.
-
(1997)
Genes and Development
, vol.11
, pp. 72-82
-
-
Tian, H.1
McKnight, S.2
Russell, D.3
-
86
-
-
0000685312
-
Sur l'augmentation considérable du nombre des globules rouges dans le sang chez les habitants des hauts plateaux de 1'Amérique du Sud
-
Viault, F. (1890) Sur l'augmentation considérable du nombre des globules rouges dans le sang chez les habitants des hauts plateaux de 1'Amérique du Sud. Comptes Rendus Hebdomaires des Seances de l'Académie des Sciences, Paris, 111, 917 918.
-
(1890)
Comptes Rendus Hebdomaires des Seances de l'Académie des Sciences, Paris
, vol.111
, pp. 917-918
-
-
Viault, F.1
-
87
-
-
2342572983
-
Optimal hemoglobin concentration and high altitude: A theoretical approach for Andean men at rest
-
Villafuerte, F.C., Cardenas, R. Monge, C.C. (2004) Optimal hemoglobin concentration and high altitude: a theoretical approach for Andean men at rest. Journal of Applied Physiology, 96, 1581 1588.
-
(2004)
Journal of Applied Physiology
, vol.96
, pp. 1581-1588
-
-
Villafuerte, F.C.1
Cardenas, R.2
Monge, C.C.3
-
88
-
-
0014095282
-
Cardiopulmonary responses of resting man during early exposure to high altitude
-
Vogel, J.A. Harris, C.W. (1967) Cardiopulmonary responses of resting man during early exposure to high altitude. Journal of Applied Physiology, 22, 1124 1128.
-
(1967)
Journal of Applied Physiology
, vol.22
, pp. 1124-1128
-
-
Vogel, J.A.1
Harris, C.W.2
-
89
-
-
15044360562
-
The pathway for IRP2 degradation involving 2-oxoglutarate-dependent oxygenase(s) does not require the E3 ubiquitin ligase activity of pVHL
-
Wang, J. Pantopoulos, K. (2005) The pathway for IRP2 degradation involving 2-oxoglutarate-dependent oxygenase(s) does not require the E3 ubiquitin ligase activity of pVHL. Biochimica et Biophysica Acta, 1743, 79 85.
-
(2005)
Biochimica et Biophysica Acta
, vol.1743
, pp. 79-85
-
-
Wang, J.1
Pantopoulos, K.2
-
90
-
-
0027210562
-
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia
-
Wang, G.L. Semenza, G.L. (1993a) General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proceedings of the National Academy of Sciences U S A, 90, 4304 4308.
-
(1993)
Proceedings of the National Academy of Sciences U S a
, vol.90
, pp. 4304-4308
-
-
Wang, G.L.1
Semenza, G.L.2
-
91
-
-
0027136260
-
Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: Implications for models of hypoxia signal transduction
-
Wang, G.L. Semenza, G.L. (1993b) Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction. Blood, 82, 3610 3615.
-
(1993)
Blood
, vol.82
, pp. 3610-3615
-
-
Wang, G.L.1
Semenza, G.L.2
-
93
-
-
1642458415
-
Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity
-
Wang, J., Chen, G., Muckenthaler, M., Galy, B., Hentze, M.W. Pantopoulos, K. (2004) Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity. Molecular and Cellular Biology, 24, 954 965.
-
(2004)
Molecular and Cellular Biology
, vol.24
, pp. 954-965
-
-
Wang, J.1
Chen, G.2
Muckenthaler, M.3
Galy, B.4
Hentze, M.W.5
Pantopoulos, K.6
-
94
-
-
0021797913
-
Serum immunoreactive erythropoietin in hypoxic lung disease with and without polycythaemia
-
Wedzicha, J.A., Cotes, P.M., Empey, D.W., Newland, A.C., Royston, J.P. Tam, R.C. (1985) Serum immunoreactive erythropoietin in hypoxic lung disease with and without polycythaemia. Clinical Science, 69, 413 422.
-
(1985)
Clinical Science
, vol.69
, pp. 413-422
-
-
Wedzicha, J.A.1
Cotes, P.M.2
Empey, D.W.3
Newland, A.C.4
Royston, J.P.5
Tam, R.C.6
-
95
-
-
27744529463
-
Acute oxygen-sensing mechanisms
-
Weir, E.K., Lopez-Barneo, J., Buckler, K.J. Archer, S.L. (2005) Acute oxygen-sensing mechanisms. New England Journal of Medicine, 353, 2042 2055.
-
(2005)
New England Journal of Medicine
, vol.353
, pp. 2042-2055
-
-
Weir, E.K.1
Lopez-Barneo, J.2
Buckler, K.J.3
Archer, S.L.4
-
97
-
-
0032189844
-
Induction of endothelial PAS domain protein-1 by hypoxia: Characterization and comparison with hypoxia-inducible factor-1α
-
Wiesener, M.S., Turley, H., Allen, W.E., Willam, C., Eckardt, K.U., Talks, K.L., Wood, S.M., Gatter, K.C., Harris, A.L., Pugh, C.W., Ratcliffe, P.J. Maxwell, P.H. (1998) Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1α. Blood, 92, 2260 2268.
-
(1998)
Blood
, vol.92
, pp. 2260-2268
-
-
Wiesener, M.S.1
Turley, H.2
Allen, W.E.3
Willam, C.4
Eckardt, K.U.5
Talks, K.L.6
Wood, S.M.7
Gatter, K.C.8
Harris, A.L.9
Pugh, C.W.10
Ratcliffe, P.J.11
Maxwell, P.H.12
-
98
-
-
0021324125
-
Red cell function at extreme altitude on Mount Everest
-
Winslow, R.M., Samaja, M. West, J.B. (1984) Red cell function at extreme altitude on Mount Everest. Journal of Applied Physiology, 56, 109 116.
-
(1984)
Journal of Applied Physiology
, vol.56
, pp. 109-116
-
-
Winslow, R.M.1
Samaja, M.2
West, J.B.3
-
99
-
-
0033104847
-
Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
-
Yu, A.Y., Shimoda, L.A., Iyer, N.V., Huso, D.L., Sun, X., McWilliams, R., Beaty, T., Sham, J.S.K., Wiener, C.M., Sylvester, J.T. Semenza, G.L. (1999) Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α. Journal of Clinical Investigation, 103, 691 696.
-
(1999)
Journal of Clinical Investigation
, vol.103
, pp. 691-696
-
-
Yu, A.Y.1
Shimoda, L.A.2
Iyer, N.V.3
Huso, D.L.4
Sun, X.5
McWilliams, R.6
Beaty, T.7
Sham, J.S.K.8
Wiener, C.M.9
Sylvester, J.T.10
Semenza, G.L.11
-
100
-
-
0035859692
-
HIF-1α binding to VHL is regulated by stimulus-sensitive proline hydroxylation
-
Yu, F., White, S.B., Zhao, Q. Lee, F.S. (2001) HIF-1α binding to VHL is regulated by stimulus-sensitive proline hydroxylation. Proceedings of the National Academy of Sciences U S A, 98, 9630 9635.
-
(2001)
Proceedings of the National Academy of Sciences U S a
, vol.98
, pp. 9630-9635
-
-
Yu, F.1
White, S.B.2
Zhao, Q.3
Lee, F.S.4
-
101
-
-
34249106715
-
A randomised placebo-controlled trial to determine the effect of iron supplementation on pregnancy outcome in pregnant women with haemoglobin ≥ 13·2 g/dl
-
Ziaei, S., Norrozi, M., Faghihzadeh, S. Jafarbegloo, E. (2007) A randomised placebo-controlled trial to determine the effect of iron supplementation on pregnancy outcome in pregnant women with haemoglobin ≥ 13·2 g/dl. BJOG, 114, 684 688.
-
(2007)
BJOG
, vol.114
, pp. 684-688
-
-
Ziaei, S.1
Norrozi, M.2
Faghihzadeh, S.3
Jafarbegloo, E.4
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