Monozygotic twins discordant for constitutive BRCA1 promoter methylation, childhood cancer and secondary cancer

Epigenetics

Volumn 7, Issue 1, 2012, Pages 47-54

  Galetzka, Danuta ^a   Hansmann, Tamara ^b   el Hajj, Nady ^b   Weis, Eva ^a   Irmscher, Benjamin ^a   Ludwig, Marco ^a   Schneider Rätzke, Brigitte ^a   Kohlschmidt, Nicolai ^a   Beyer, Vera ^a   Bartsch, Oliver ^a   Zechner, Ulrich ^a   Spix, Claudia ^a   Haaf, Thomas ^b  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

BRCA1; Childhood cancer; DNA methylation; Epimutation; Monozygotic twins; Secondary cancer; Somatic mosaicism

Indexed keywords

BRCA1 PROTEIN;

ALLELE; ARTICLE; CASE REPORT; CELL LINEAGE; CHILD; CHILDHOOD LEUKEMIA; CPG ISLAND; DNA METHYLATION; EMBRYO CELL; FEMALE; FIBROBLAST; GENE DELETION; GENE EXPRESSION; GENE SEQUENCE; HETEROZYGOSITY; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; MONOZYGOTIC TWINS; MOSAICISM; PLASMID; PROMOTER REGION; PYROSEQUENCING; SECOND CANCER; THYROID CARCINOMA; TUMOR SUPPRESSOR GENE; TWIN DISCORDANCE;

EID: 84856241096     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.7.1.18814     Document Type: Article

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