WRNIP1 accumulates at laser light irradiated sites rapidly via its ubiquitin-binding zinc finger domain and independently from its ATPase domain

Biochemical and Biophysical Research Communications

Volumn 417, Issue 4, 2012, Pages 1145-1150

  Nomura, Hironoshin ^a   Yoshimura, Akari ^b   Edo, Takato ^a   Kanno, Shin Ichiro ^a   Tada, Syusuke ^c   Seki, Masayuki ^a   Yasui, Akira ^a   Enomoto, Takemi ^b  

^a TOHOKU UNIVERSITY   (Japan)

^b MUSASHINO UNIVERSITY   (Japan)

^c TEIKYO HEISEI UNIVERSITY   (Japan)

Author keywords

ATPase; DNA damage; Ubiquitin; UBZ; WRNIP1

Indexed keywords

ADENOSINE TRIPHOSPHATASE; GREEN FLUORESCENT PROTEIN; LEUCINE ZIPPER PROTEIN; POLYUBIQUITIN; UBIQUITIN; UNCLASSIFIED DRUG; WERNER HELICASE INTERACTING PROTEIN 1; WERNER SYNDROME PROTEIN; ZINC FINGER PROTEIN;

ARTICLE; DNA DAMAGE; FEMALE; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; LASER; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; UBIQUITINATION;

ADENOSINE TRIPHOSPHATASES; CARRIER PROTEINS; DNA DAMAGE; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; LASERS; LEUCINE ZIPPERS; LIGHT; LYSINE; MUTATION; PROTEIN STRUCTURE, TERTIARY; UBIQUITIN; UBIQUITINATION; ZINC FINGERS;

EID: 84856223865     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.12.080     Document Type: Article

References (29)

1. Yu C.E., Oshima J., Fu Y.H., Wijsman E.M., Hisama F., Alisch R., Matthews S., Nakura J., Miki T., Ouais S., Martin G.M., Mulligan J., Schellenberg G.D. Positional cloning of the Werner's syndrome gene. Science 1996, 272:258-262.
2. Hickson I.D. RecQ helicases: caretakers of the genome. Nat. Rev. Cancer 2003, 3:169-178.
3. Opresko P.L., Cheng W.H., von Kobbe C., Harrigan J.A., Bohr V.A. Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process. Carcinogenesis 2003, 24:791-802.
4. Epstein C.J., Motulsky A.G. Werner syndrome: entering the helicase era. Bioassays 1996, 18:1025-1027.
5. Goto M. Werner's syndrome: from clinics to genetics. Clin. Exp. Rheumatol. 2000, 18:760-766.
6. Kawabe Y., Branzei D., Hayashi T., Suzuki H., Masuko T., Onoda F., Heo S.J., Ikeda H., Shimamoto A., Furuichi Y., Seki M., Enomoto T. A novel protein interacts with the Werner's syndrome gene product physically and functionally. J. Biol. Chem. 2001, 276:20364-20369.
7. Hishida T., Iwasaki H., Ohno T., Morishita T., Shinagawa H. A yeast gene, MGS1, encoding a DNA-dependent AAA(+) ATPase is required to maintain genome stability. Proc. Natl. Acad. Sci. USA 2001, 98:8283-8289.
8. Kawabe Y., Seki M., Yoshimura A., Nishino K., Hayashi T., Takeuchi T., Iguchi S., Kusa Y., Ohtsuki M., Tsuyama T., Imamura O., Matsumoto T., Furuichi Y., Tada S., Enomoto T. Analyses of the interaction of WRNIP1 with Werner syndrome protein (WRN) in vitro and in the cell. DNA Repair (Amst) 2006, 5:816-828.
9. Bish R.A., Myers M.P. Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain. J. Biol. Chem. 2007, 282:23184-23193.
10. Bienko M., Green C.M., Crosetto N., Rudolf F., Zapart G., Coull B., Kannouche P., Wider G., Peter M., Lehmann A.R., Hofmann K., Dikic I. Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis. Science 2005, 310:1821-1824.
11. Notenboom V., Hibbert R.G., van Rossum-Fikkert S.E., Olsen J.V., Mann M., Sixma T.K. Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification. Nucleic Acids Res. 2007, 35:5819-5830.
12. Hishida T., Ohno T., Iwasaki H., Shinagawa H. Saccharomyces cerevisiae MGS1 is essential in strains deficient in the RAD6-dependent DNA damage tolerance pathway. EMBO J. 2002, 21:2019-2029.
13. Branzei D., Seki M., Onoda F., Enomoto T. The product of Saccharomyces cerevisiae WHIP/MGS1, a gene related to replication factor C genes, interacts functionally with DNA polymerase delta. Mol. Genet. Genomics 2002, 268:371-386.
14. Yoshimura A., Seki M., Kanamori M., Tateishi S., Tsurimoto T., Tada S., Enomoto T. Physical and functional interaction between WRNIP1 and RAD18. Genes Genet. Syst. 2009, 84:171-178.
15. Hoege C., Pfander B., Moldovan G.L., Pyrowolakis G., Jentsch S. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 2002, 419:135-141.
16. Prakash S., Johnson R.E., Prakash L. Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function. Annu. Rev. Biochem. 2005, 74:317-353.
17. Saugar I., Parker J.L., Zhao S., Ulrich H.D. The genome maintenance factor Mgs1 is targeted to sites of replication stress by ubiquitylated PCNA. Nucleic Acids Res. 2011.
18. Crosetto N., Bienko M., Hibbert R.G., Perica T., Ambrogio C., Kensche T., Hofmann K., Sixma T.K., Dikic I. Human Wrnip1 is localized in replication factories in a ubiquitin-binding zinc finger-dependent manner. J. Biol. Chem. 2008, 283:35173-35185.
19. Lan L., Nakajima S., Oohata Y., Takao M., Okano S., Masutani M., Wilson S.H., Yasui A. In situ analysis of repair processes for oxidative DNA damage in mammalian cells. Proc. Natl. Acad. Sci. USA 2004, 101:13738-13743.
20. Lan L., Nakajima S., Komatsu K., Nussenzweig A., Shimamoto A., Oshima J., Yasui A. Accumulation of Werner protein at DNA double-strand breaks in human cells. J. Cell Sci. 2005, 118:4153-4162.
21. Tsurimoto T., Shinozak A., Yano M., Seki M., Enomoto T. Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta. Genes Cells 2005, 10:13-22.
22. Kim J.H., Kang Y.H., Kang H.J., Kim D.H., Ryu G.H., Kang M.J., Seo Y.S. In vivo and in vitro studies of Mgs1 suggest a link between genome instability and Okazaki fragment processing. Nucleic Acids Res. 2005, 33:6137-6150.
23. Haracska L., Torres-Ramos C.A., Johnson R.E., Prakash S., Prakash L. Opposing effects of ubiquitin conjugation and SUMO modification of PCNA on replicational bypass of DNA lesions in Saccharomyces cerevisiae. Mol. Cell. Biol. 2004, 24:4267-4274.
24. Lehmann A.R., Niimi A., Ogi T., Brown S., Sabbioneda S., Wing J.F., Kannouche P.L., Green C.M. Translesion synthesis: Y-family polymerases and the polymerase switch. DNA Repair (Amst) 2007, 6:891-899.
25. Ulrich H.D. Regulating post-translational modifications of the eukaryotic replication clamp PCNA. DNA Repair (Amst) 2009, 8:461-469.
26. Bergink S., Jentsch S. Principles of ubiquitin and SUMO modifications in DNA repair. Nature 2009, 458:461-467.
27. Branzei D., Vanoli F., Foiani M. SUMOylation regulates Rad18-mediated template switch. Nature 2008, 456:915-920.
28. Vijeh Motlagh N.D., Seki M., Branzei D., Enomoto T. Mgs1 and Rad18/Rad5/Mms2 are required for survival of Saccharomyces cerevisiae mutants with novel temperature/cold sensitive alleles of the DNA polymerase delta subunit, Pol31. DNA Repair (Amst) 2006, 5:1459-1474.
29. Branzei D., Seki M., Onoda F., Yagi H., Kawabe Y., Enomoto T. Characterization of the slow-growth phenotype of S. cerevisiae Whip/Mgs1 Sgs1 double deletion mutants. DNA Repair (Amst) 2002, 1:671-682.