Synthesis of piperine-amino acid ester conjugates and study of their cytotoxic activities against human cancer cell lines

Medicinal Chemistry Research

Volumn 21, Issue 1, 2012, Pages 38-46

  Rao, V Rama Subba ^a   Suresh, G ^a   Rao, R Ranga ^a   Babu, K Suresh ^a   Chashoo, G ^b   Saxena, A K ^b   Rao, J Madhusudana ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

Amide linkage; Amino acid conjugates; Boric acid; Cytotoxic activity; Peptide linkage; Piper nigrum; Piperine; Piperoic acid

Indexed keywords

AMINO ACID; ANTINEOPLASTIC AGENT; DIMETHYL 2 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMIDO]SUCCINATE; DOXORUBICIN; ESTER; FLUOROURACIL; METHYL 1 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMIDO]PYRROLIDINE 2 CARBOXYLATE; METHYL 2 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMID]ACETATE; METHYL 2 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMIDO] 2 PHENYLACETATE; METHYL 2 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMIDO] 3 (1H IMIDAZOL 5 YL)PROPANOATE; METHYL 2 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMIDO] 3 (1H INDOL 3 YL)PROPANOATE; METHYL 2 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMIDO] 3 (2 DIHYDROXYPHENYL)PROPANOATE; METHYL 2 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMIDO] 3 (4 HYDROXYPHENYL)PROPANOATE; METHYL 2 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMIDO] 3 HYDROXYPROPANOATE; METHYL 2 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMIDO] 3 METHYLBUTANOATE; METHYL 2 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMIDO] 3 METHYLPENTANOATE; METHYL 2 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMIDO] 3 PHENYLPROPANOATE; METHYL 2 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMIDO] 4 METHYLPENTANOATE; METHYL 2 [5 (BENZO[D][1,3]DIOXOL 6 YL)PENTA 2,4 DIENAMIDO]PROPANOATE; MITOMYCIN C; PEPTIDE; PIPERINE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CELL STRAIN MCF 7; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; HEP 2 CELL; HUMAN; HUMAN CELL; NEUROBLASTOMA; PROSTATE CANCER; STRUCTURE ACTIVITY RELATION;

EID: 84856219751     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-010-9500-5     Document Type: Article

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