Mitochondrial monolysocardiolipin acyltransferase is elevated in the surviving population of H9c2 cardiac myoblast cells exposed to 2-deoxyglucose-induced apoptosis

Biochemistry and Cell Biology

Volumn 86, Issue 1, 2008, Pages 11-20

  Danos, Maria ^a   Taylor, William A ^a   Hatch, Grant M ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

2 dexoyglucose; Acyllysocardiolipin acyltransferase; Acyltransferase; ALCAT1; Apoptosis; Barth syndrome; Cardiolipin; Heart; Hypoglycemia; Hypoxia; Lipid metabolism; Mitochondria; Monolysocardiolipin; Phospholipid; Reactive oxygen species; Tafazzin; TAZ

Indexed keywords

ACYLLYSOCARDIOLIPIN ACYLTRANSFERASE; ACYLTRANSFERASE; CARDIOLIPIN; DEXOYGLUCOSE; HYPOGLYCEMIA; HYPOXIA; LIPID METABOLISM; MONOLYSOCARDIOLIPIN; REACTIVE OXYGEN SPECIES; TAFAZZIN;

CELL DEATH; FATTY ACIDS; GLYCEROL; MAMMALS; MITOCHONDRIA; PHOSPHOLIPIDS;

ENZYMES;

ACYLTRANSFERASE; ALBUMIN; CARDIOLIPIN; CASPASE 3; DEOXYGLUCOSE; FATTY ACID; GLYCEROL; LINOLEIC ACID; MESSENGER RNA; MONOLYSOCARDIOLIPIN ACYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHOLIPASE A2; PROTEIN DERIVATIVE; PROTEIN TAZ; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BARTH SYNDROME; CELL POPULATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC CODE; INCUBATION TIME; LIPID COMPOSITION; MITOCHONDRIAL MEMBRANE; MYOBLAST; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RADIOACTIVITY; UPREGULATION;

1-ACYLGLYCEROPHOSPHOCHOLINE O-ACYLTRANSFERASE; ACYLTRANSFERASES; ANIMALS; APOPTOSIS; CARDIOLIPINS; CELL LINE; DEOXYGLUCOSE; MITOCHONDRIA; MYOBLASTS, CARDIAC; PHOSPHOLIPASES A2; RATS;

MAMMALIA;

EID: 39049115899     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/O07-156     Document Type: Article

References (51)

1. Aki, T., Yoshida, T., and Fujimiya, T. 2002. Phosphoinositide 3-kinase accelerates calpain-dependent proteolysis of fodrin during hypoxic cell death. J. Biochem. (Tokyo), 132: 921-926.
2. Campling, B.G., Pym, J., Baker, H.M., Cole, S.P., and Lam, Y.M. 1991. Chemosensitivity testing of small cell lung cancer using the MTT assay. Br. J. Cancer, 63: 75-83.
3. Cao, S.G., Angel, A., and Hatch, G.M. 1995. Decrease in cardiac phosphatidylglycerol in streptozotocin-induced diabetic rats does not affect cardiolipin biosynthesis: evidence for distinct pools of phosphatidylglycerol in the heart. Biochem. J. 306: 759-764.
4. Cao, J., Liu, Y., Lockwood, J., Burn, P., and Shi, Y. 2004. A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated acyl-CoA:lysocardiolipin acyltransferase (ALCAT1) in mouse. J. Biol. Chem. 279: 31727-31734. doi:10.1074/jbc.M402930200.
5. Choi, S.-Y., Gonzalvez, F., Jenkins, G.M., Slomianny, C., Chretien, D., Arnoult, D., et al. 2007. Cardiolipin deficiency releases cytochrome c from the inner mitochondrial membrane and accelerates stimuli-elicited apoptosis. Cell Death Differ. 14: 597-606. doi:10.1038/sj.cdd.4402020.
6. Cybulsky, A.V., Takano, T., Papillon, J., and Bijian, K. 2005. Role of the endoplasmic reticulum unfolded protein response in glomerular epithelial cell injury. J. Biol. Chem. 280: 24396-24403. doi:10.1074/jbc.M500729200.
7. Duriez, P.J., and Shah, G.M. 1997. Cleavage of poly(ADP-ribose) polymerase: a sensitive parameter to study cell death. Biochem. Cell Biol. 75: 337-349. doi:10.1139/bcb-75-4-337.
8. Eichberg, J. 1974. The reacylation of deacylated derivatives of diphosphatidylglycerol by microsomes and mitochondria from rat liver. J. Biol. Chem. 249: 3423-3429.
9. Epand, R.F., Tokarska-Schlattner, M., Schlattner, U., Wallimann, T., and Epand, R.M. 2007. Cardiolipin clusters and membrane domain formation induced by mitochondrial proteins. J. Mol. Biol. 365: 968-980. doi:10.1016/j.jmb. 2006.10.028.
10. Esposti, M.D. 2002. Lipids, cardiolipin and apoptosis: a greasy license to kill. Cell Death Differ. 9: 234-236. doi:10.1038/sj.cdd.4400997.
11. Esposti, M.D., Cristea, I.M., Gaskell, S.J., Nakao, Y., and Dive, C. 2003. Proapoptotic Bid binds to monolysocardiolipin, a new molecular connection between mitochondrial membranes and cell death. Cell Death Differ. 10: 1300-1309. doi:10.1038/sj.cdd.4401306.
12. Garrido, C., Galluzzi, L., Brunet, M., Puig, P.E., Didelot, C., and Kroemer, G. 2006. Mechanisms of cytochrome c release from mitochondria. Cell Death Differ. 13: 1423-1433. doi:10.1038/sj.cdd.4401950.
13. Hatch, G.M. 1994. Cardiolipin biosynthesis in the isolated heart. Biochem. J. 297: 201-208.
14. Hatch, G.M. 2004. Cell biology of cardiac mitochondrial phospholipids. Biochem. Cell Biol. 82: 99-112. doi:10.1139/o03-074.
15. Hatch, G.M., and McClarty, G. 1996. Regulation of cardiolipin biosynthesis in H9c2 cardiac myoblasts by cytidine 5′-triphosphate. J. Biol. Chem. 271: 25810-25816. doi:10.1074/jbc.271.42.25810.
16. Hoch, F.L. 1992. Cardiolipins and biomembrane function. Biochim. Biophys. Acta, 1113: 71-133.
17. Hostetler, K.Y. 1982. Polyglycerolphospholipids. Phospholipids. Elsevier, Amsterdam. pp. 215-242.
18. Hostetler, K.Y., Galesloot, J.M., Boer, P., and Van den Bosch, H. 1975. Further studies on the formation of cardiolipin and phosphatidylglycerol in rat liver mitochondria. Effect of divalent cations and the fatty acid composition of CDP-diglyceride. Biochim. Biophys. Acta, 380: 382-389.
19. Kuijpers, T.W., Maianski, N.A., Tool, A.T., Becker, K., Plecko, B., Valianpour, F., et al. 2004. Neutrophils in Barth syndrome (BTHS) avidly bind annexin-V in the absence of apoptosis. Blood, 103: 3915-3923. doi:10.1182/blood-2003-11-3940.
20. Lands, W.E. 2000. Stories about acyl chains. Biochim. Biophys. Acta, 1483: 1-14.
21. Lin, H.Y., Masso-Welch, P., Di, Y.P., Cai, J.W., Shen, J.W., and Subjeck, J.R. 1993. The 170-kDa glucose-regulated stress protein is an endoplasmic reticulum protein that binds immunoglobulin. Mol. Biol. Cell, 4: 1109-1119.
22. Liu, J., Dai, Q., Freeman, A., Chen, J., Grossman, D., and Lee, R.M. 2003. Phospholipid scramblase 3 controls mitochondrial structure, function and apoptotic response. Mol. Cancer Res. 1: 892-902.
23. Liu, J., Durrant, D., Yang, H.S., He, Y., Whitby, F.G., Myszka, D.G., and Lee, R.M. 2005. The interaction between tBid and cardiolipin or monolysocardiolipin. Biochem. Biophys. Res. Commun. 330: 865-870. doi:10.1016/j.bbrc.2005.03.048.
24. Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265-275.
25. Lu, B., Kehler, M.R., Lee, D.P., Lewin, T.M., Coleman, R.A., Choy, P.C., and Hatch, G.M. 2004. Complex expression pattern of the Barth syndrome gene product tafazzin in human cell lines and murine tissues. Biochem. Cell Biol. 82: 569-576. doi:10.1139/o04-055.
26. Lutter, M., Fang, M., Luo, X., Nishijima, M., Xie, X., and Wang, X. 2000. Cardiolipin provides specificity for targeting of tBid to mitochondria. Nat. Cell Biol. 2: 754-761. doi:10.1038/35036395.
27. Ma, B.J., and Hatch, G.M. 2000. Monolysocardiolipin acyltransferase activity: effect of insulin and localization of activity. Proc. West. Pharmacol. Soc. 43: 39-41.
28. Ma, B.J., Taylor, W.A., Dolinsky, V.W., and Hatch, G.M. 1999. Acylation of monolysocardiolipin in rat heart. J. Lipid Res. 40: 1837-1845.
29. MacDonald, J.I., and Sprecher, H. 1991. Phospholipid fatty acid remodeling in mammalian cells. Biochim. Biophys. Acta, 1084: 105-121.
30. Nomura, K., Imai, H., Koumura, T., Arai, M., and Nakagawa, Y. 1999. Mitochondrial phospholipid hydroperoxide glutathione peroxidase suppresses apoptosis mediated by a mitochondrial death pathway. J. Biol. Chem. 274: 29294-29302. doi:10.1074/jbc.274.41.29294.
31. Nomura, K., Imai, H., Koumura, T., Kobayashi, T., and Nakagawa, Y. 2000. Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis. Biochem. J. 351: 183-193. doi:10.1042/0264-6021:3510183.
32. Ott, M., Gogvadze, V., Orrenius, S., and Zhivotovsky, B. 2007a. Mitochondria, oxidative stress and cell death. Apoptosis, 12: 913-922. doi:10.1007/s10495-007-0756-2.
33. Ott, M., Zhivotovsky, B., and Orrenius, S. 2007b. Role of cardiolipin in cytochrome c release from mitochondria. Cell Death Differ. 14: 1243-1247. doi:10.1038/sj.cdd.4402135.
34. Polcic, P., Su, X., Fowlkes, J., Blachly-Dyson, E., Dowhan, W., and Forte, M. 2005. Cardiolipin and phosphatidylglycerol are not required for the in vivo action of Bcl-2 family proteins. Cell Death Differ. 12: 310-312. doi:10.1038/sj.cdd.4401566.
35. Reig, J., Domingo, E., Segura, R., Tovar, J.L., Vinallonga, M., and And Borrell, M. 1993. Rat myocardial tissue lipidsand their effects on ventricular electrical activity: influence of dietary lipids. Cardiovasc. Res. 27: 364-370.
36. Rouser, G., Fleischer, S., and Yamamoto, A. 1970. Two dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots. Lipids, 5: 494-496. doi:10.1007/BF02531316.
37. Schlame, M., and Rustow, B. 1990. Lysocardiolipin formation and reacylation in isolated rat liver mitochondria. Biochem. J. 272: 589-595.
38. Schlame, M., Brody, S., and Hostetler, K.Y. 1993. Mitochondrial cardiolipin in diverse eukaryotes. Comparison of biosynthetic reactions and molecular acyl species. Eur. J. Biochem. 212: 727-735. doi:10.1111/j.1432-1033.1993.tb17711.x.
39. Schlame, M., Rua, D., and Greenberg, M.L. 2000. The biosynthesis and functional role of cardiolipin. Prog. Lipid Res. 39: 257-288. doi:10.1016/S0163-7827(00)00005-9.
40. 2 localizes in and protects mitochondria during apoptotic induction by staurosporine. J. Biol. Chem. 281: 22275-22288. doi:10.1074/jbc.M604330200.
41. Sorice, M., Circella, A., Cristea, I.M., Garofalo, T., Di Renzo, L., Alessandri, C., et al. 2004. Cardiolipin and its metabolites move from mitochondria to other cellular membranes during death receptor-mediated apoptosis. Cell Death Differ. 11: 1133-1145. doi:10.1038/sj.cdd.4401457.
42. Taylor, W.A., and Hatch, G.M. 2003. Purification and characterization of monolysocardiolipin acyltransferase from pig liver mitochondria. J. Biol. Chem. 278: 12716-12721. doi:10.1074/jbc.M210329200.
43. Valianpour, F., Mitsakos, V., Schlemmer, D., Towbin, J.A., Taylor, J.M., Ekert, P.G., et al. 2005. Monolysocardiolipins accumulate in Barth syndrome but do not lead to enhanced apoptosis. J. Lipid Res. 46: 1182-1195. doi:10.1194/jlr.M500056-JLR200.
44. Van, Q., Liu, J., Lu, B., Feingold, K.R., Shi, Y., Lee, R.M., and Hatch, G.M. 2007. Phospholipid scramblase-3 regulates cardiolipin de novo biosynthesis and its resynthesis in growing HeLa cells. Biochem. J. 401: 103-109. doi:10.1042/BJ20060373.
45. Vance, J.E. 2003. Molecular and cell biology of phosphatidylserine and phosphatidylethanolamine metabolism. Prog. Nucleic Acid Res. Mol. Biol. 75: 69-111.
46. Van den Bosch, H., Postema, N.M., de Haas, G.H., and Van Deenen, L.L. 1965. On the positional specificity of phospholipase A from pancreas. Biochim. Biophys. Acta, 98: 657-659.
47. Wang, C., Faloon, P.W., Tan, Z., Lv, Y., Zhang, P., Ge, Y., et al. 2007. Mouse lysocardiolipin acyltransferase controls the development of hematopoietic and endothelial lineages during in vitro embryonic stem-cell differentiation. Blood, 110: 3601-3609. doi:10.1182/blood-2007-04-086827.
48. Xu, F.Y., Kelly, S.L., and Hatch, G.M. 1999. N-acetylsphingosine stimulates phosphatidylglycerolphosphate synthase activity in H9c2 cardiac cells. Biochem. J. 337: 483-490. doi:10.1042/0264-6021:3370483.
49. Xu, Y., Kelley, R.I., Blank, T.J.J., and Schlame, M. 2003. Remodeling of cardiolipin by phospholipid transacylation. J. Biol. Chem. 278: 51380-51385. doi:10.1074/jbc.M307382200.
50. Xu, Y., Malhotra, A., Ren, M., and Schlame, M. 2006. The enzymatic function of tafazzin. J. Biol. Chem. 281: 39217-39224. doi:10.1074/jbc.M606100200.
51. Zhang, M., Mileykovskaya, E., and Dowhan, W. 2002. Gluing the respiratory chain together. Cardiolipin is required for supercomplex formation in the inner mitochondrial membrane. J. Biol. Chem. 277: 43553-43556. doi:10.1074/jbc.C200551200.