A practical synthesis of a chiral analogue of FTY720

Organic Process Research and Development

Volumn 12, Issue 6, 2008, Pages 1164-1169

  Jiang, Xinglong ^a   Gong, Baoqing ^a   Prasad, Kapa ^a   Repič, Oljan ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 58149141785     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op800144h     Document Type: Article

References (12)

1. (a) Brinkmann, V. Yonsei Med. J. 2004, 45, 991-997.
2. (b) Chiba, K. Pharmacol. Ther. 2005, 108, 308-319.
3. (c) Albert, R.; Hinterding, K.; Brinkmann, V.; Guerini, D.; Müller-Hartwieg, C.; Knecht, H.; Simeon, C.; Streiff, M.; Wagner, T.; Welzenbach, K.; Zécri, F.; Zollinger, M.; Cooke, N.; Francotte, E. J. Med. Chem. 2005, 48, 5373-5377.
4. (a) Hinterding, K.; Cottens, S.; Albert, R.; Zecri, F.; Buehlmayer, P.; Spanka, C.; Brinkmann, V.; Nussbaumer, P.; Ettmayer, P.; Hoegenauer, K.; Gray, N.; Pan, S. Synthesis 2003, 1667.
5. (b) Buehlmayer, P.; Hinterding, K.; Spanka, C.; Zecri, F., WO 2004/024673, CAN 140: 287164 AN 2004:252472, 2004.
6. (a) Schölkopf, U.; Groth, U.; Westphalen, K.-O.; Deng, C. Synthesis 1981, 12, 969.
7. (b) Schölkopf, U. Pure Appl. Chem. 1983, 55, 1799.
8. Starks, C. M. J. Am. Chem. Soc. 1971, 93, 195.
9. Maruoka, K. Asymmetric Phase Transfer Catalysis; Wiley-VCH Verlag Gmbh & Co., KGaA: Weinheim, 2008 and references therein.
10. Zeevaart, J. G.; Parkinson, C. J.; de Koning, C. B. Tetrahedron Lett. 2004, 45, 4261.
11. Trost, B. M.; Shen, H. C.; Dong, Li; Surivet, J.-P.; Sylvain, C. J. Am. Chem, Soc, 2004, 126, 11966.
12. Maruoka, K.; Ooi, T. Chem. Rev. 2003, 103, 3013-3028.