Magnetic silica nanoparticle cellular uptake and cytotoxicity regulated by electrostatic polyelectrolytes-DNA loading at their surface

ACS Nano

Volumn 6, Issue 1, 2012, Pages 747-759

  Davila Ibanez, Ana B ^a   Salgueirino, Veronica ^a   Martinez Zorzano, Vicenta ^a   Mariño Fernández, Rosalia ^a   García Lorenzo, Andres ^a   MacEira Campos, Melodie ^a   Muñoz Ubeda, Monica ^b   Junquera, Elena ^b   Aicart, Emilio ^b   Rivas, Jose ^c   Rodriguez Berrocal, F Javier ^a   Legido, Jose L ^a  

^a UNIVERSITY OF VIGO   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c INTERNATIONAL IBERIAN NANOTECHNOLOGY LABORATORY   (Portugal)

Author keywords

cellular uptake; cytotoxicity; DNA compaction; magnetoplexes; polyelectrolytes

Indexed keywords

BIOFUNCTIONALIZATION; CELLULAR UPTAKE; CHEMICAL DEGRADATION; DNA COMPACTION; DNA FRAGMENT; MAGNETIC NATURE; MAGNETOPLEXES; NEGATIVE CHARGE; POSITIVE CHARGES; SILICA NANOPARTICLES; SURFACE FUNCTIONALIZATION;

CYTOTOXICITY; DNA; DRUG DELIVERY; NANOPARTICLES; POLYELECTROLYTES; SILICA; SURFACES; TISSUE;

NANOMAGNETICS;

DNA; MAGNETITE NANOPARTICLE; SILICON DIOXIDE;

ANIMAL; ARTICLE; CELL STRAIN CACO 2; CELL SURVIVAL; CHEMISTRY; DIFFUSION; DRUG EFFECT; HUMAN; MATERIALS TESTING; STATIC ELECTRICITY; SURFACE PROPERTY;

ANIMALS; CACO-2 CELLS; CELL SURVIVAL; DIFFUSION; DNA; HUMANS; MAGNETITE NANOPARTICLES; MATERIALS TESTING; SILICON DIOXIDE; STATIC ELECTRICITY; SURFACE PROPERTIES;

EID: 84856144536     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn204231g     Document Type: Article

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