Neuromuscular blocking agents in ARDS

New England Journal of Medicine

Volumn 363, Issue 12, 2010, Pages 1176-1180

  Slutsky, Arthur S ^a,b  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CISATRACURIUM; NEUROMUSCULAR BLOCKING AGENT; PLACEBO; ATRACURIUM BESILATE;

ADULT RESPIRATORY DISTRESS SYNDROME; ARTIFICIAL VENTILATION; BLOOD OXYGEN TENSION; DRUG MECHANISM; EDITORIAL; HEART OUTPUT; HUMAN; MUSCLE WEAKNESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; TIDAL VOLUME; ANALOGS AND DERIVATIVES; DRUG EFFECTS; MULTIMODALITY CANCER THERAPY; RESPIRATORY DISTRESS SYNDROME, ADULT; VENTILATOR-INDUCED LUNG INJURY;

ATRACURIUM; COMBINED MODALITY THERAPY; HUMANS; NEUROMUSCULAR BLOCKING AGENTS; OXYGEN CONSUMPTION; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT; VENTILATOR-INDUCED LUNG INJURY;

EID: 77956655764     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMe1007136     Document Type: Editorial

References (15)

1. Papazian L, Forel J-M, Gacouin A, et al. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med 2010;363:1107-16.
2. The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000;342:1301-8.
3. Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000;342:1334-49.
4. Rubenfeld GD, Caldwell E, Peabody E, et al. Incidence and outcomes of acute lung injury. N Engl J Med 2005;353:1685-93. (Pubitemid 41464707)
5. Raghavendran K, Pryhuber GS, Chess PR, Davidson BA, Knight PR, Notter RH. Pharmacotherapy of acute lung injury and acute respiratory distress syndrome. Curr Med Chem 2008;15:1911-24.
6. Hébert PC, Wells G, Blajchman MA, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 1999;340:409-17. [Erratum, N Engl J Med 1999;340:1056.]
7. Kress JP. Clinical trials of early mobilization of critically ill patients. Crit Care Med 2009;37:Suppl:S442-S447.
8. Hill NS, Brennan J, Garpestad E, Nava S. Noninvasive ventilation in acute respiratory failure. Crit Care Med 2007;35:2402-7. (Pubitemid 47476241)
9. Wunsch H, Kress JP. A new era for sedation in ICU patients. JAMA 2009;301:542-4.
10. Stapleton RD, Wang BM, Hudson LD, Rubenfeld GD, Caldwell ES, Steinberg KP. Causes and timing of death in patients with ARDS. Chest 2005;128:525-32.
11. Slutsky AS, Tremblay LN. Multiple system organ failure: is mechanical ventilation a contributing factor? Am J Respir Crit Care Med 1998;157:1721-5.
12. Tremblay LN, Slutsky AS. Ventilator-induced lung injury: from the bench to the bedside. Intensive Care Med 2006;32:24-33. (Pubitemid 43039374)
13. Marini JJ. Early phase of lung-protective ventilation: a place for paralytics? Crit Care Med 2006;34:2851-3.
14. Broccard AF, Hotchkiss JR, Kuwayama N, et al. Consequences of vascular flow on lung injury induced by mechanical ventilation. Am J Respir Crit Care Med 1998;157:1935-42. (Pubitemid 28311283)
15. Forel JM, Roch A, Marin V, et al. Neuromuscular blocking agents decrease inflammatory response in patients presenting with acute respiratory distress syndrome. Crit Care Med 2006;34:2749-57. (Pubitemid 43213036)