Executing and rationalizing the synthesis of a difluorinated analogue of a ring-expanded calystegine B 2

Journal of Organic Chemistry

Volumn 77, Issue 2, 2012, Pages 991-998

  Kyne, Sara H ^a   Miles, Jonathan A L ^b,c   Percy, Jonathan M ^a   Singh, Kuldip ^b  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c ARCADIS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DENSITY FUNCTIONAL THEORY METHODS; DIFLUORINATED; EPOXIDATION REACTIONS; RING OPENING; RING-CLOSURE; STERIC CONTROL; THERMODYNAMIC CONTROL; TRANSANNULAR REACTIONS;

DENSITY FUNCTIONAL THEORY; EPOXIDATION; SYNTHESIS (CHEMICAL);

REACTION INTERMEDIATES;

AMINE; AMMONIA; CALYSTEGINE B2 DERIVATIVE; FLUORINE DERIVATIVE; NORTROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CIS TRANS ISOMERISM; CYCLIZATION; DENSITY FUNCTIONAL THEORY; DEPROTECTION REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; ENERGY; EPOXIDATION; FLUORINATION; FLUORINE NUCLEAR MAGNETIC RESONANCE; HETERONUCLEAR MULTIPLE BOND CORRELATION; MICROWAVE RADIATION; PROTON NUCLEAR MAGNETIC RESONANCE; RING CLOSING METATHESIS; RING OPENING; STEREOSPECIFICITY; STRUCTURE ANALYSIS; THERMODYNAMICS;

FLUORINE COMPOUNDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NORTROPANES; SOLANACEOUS ALKALOIDS; STEREOISOMERISM; THERMODYNAMICS;

EID: 84856108104     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo2022845     Document Type: Article

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