Site-specific integration of foreign dna into minimal bacterial and human target sequences mediated by a conjugative relaxase

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Agúndez, Leticia ^a,b   González Prieto, Coral ^a   Machón, Cristina ^a,c   Llosa, Matxalen ^a  

^a UNIVERSITY OF CANTABRIA   (Spain)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIAL PROTEIN; HELICASE; INTEGRATION HOST FACTOR; PLASMID DNA; PROTEIN TRWC; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG; DNA; DNA POLYMERASE; ESCHERICHIA COLI PROTEIN; INTEGRASE; TRWC PROTEIN, E COLI;

ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL GENOME; BACTERIUM CONJUGATION; BINDING SITE; CONTROLLED STUDY; DNA INTEGRATION; DNA MODIFICATION; DNA NICK TRANSLATION; DNA REPLICATION ORIGIN; DNA SEQUENCE; DNA TRANSFER; ESCHERICHIA COLI; GENE TARGETING; HUMAN GENOME; HUMAN VERSUS NONHUMAN DATA; NONHUMAN; PROCESS OPTIMIZATION; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; SUICIDE GENE; BIOLOGICAL MODEL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; HUMAN CHROMOSOME; METABOLISM; METHODOLOGY; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PLASMID; SITE DIRECTED MUTAGENESIS; TRANSGENIC ORGANISM;

BACTERIA (MICROORGANISMS);

BASE SEQUENCE; CHROMOSOMES, BACTERIAL; CHROMOSOMES, HUMAN; CLONING, MOLECULAR; CONJUGATION, GENETIC; DNA; DNA NUCLEOTIDYLTRANSFERASES; DNA, BACTERIAL; ESCHERICHIA COLI PROTEINS; GENE TARGETING; HUMANS; INTEGRASES; MODELS, BIOLOGICAL; MUTAGENESIS, INSERTIONAL; MUTAGENESIS, SITE-DIRECTED; ORGANISMS, GENETICALLY MODIFIED; PLASMIDS;

EID: 84856094543     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031047     Document Type: Article

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