Opposing mitogenic and anti-mitogenic actions of parathyroid hormone-related protein in vascular smooth muscle cells: A critical role for nuclear targeting

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 25, 1997, Pages 13630-13635

  Massfelder, Thierry ^a,b,c   Dann, Pamela ^a,b   Wu, Terence L ^a,b   Vasavada, Rupangi ^a,b   Helwig, Jean Jacques ^c   Stewart, Andrew F ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Alternative translational start site; Cellular proliferation; Nucleolus

Indexed keywords

CELL SURFACE RECEPTOR; PARATHYROID HORMONE RELATED PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; ATHEROSCLEROSIS; CELL CYCLE; CELL PROLIFERATION; GENE TARGETING; MITOGENESIS; PRIORITY JOURNAL; PROTEIN PROCESSING; TRANSGENE;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; CELL NUCLEUS; CELLS, CULTURED; EYE PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MITOGENS; MUSCLE, SMOOTH, VASCULAR; PARATHYROID HORMONE; PARATHYROID HORMONE-RELATED PROTEIN; PROTEINS; RATS; SEQUENCE DELETION; TRANSFECTION;

EID: 0031456826     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.25.13630     Document Type: Article

References (34)

1. Stewart, A. F., Insogna, K. L. & Broadus, A. E. (1995) in Endocrinology, ed. DeGroot, L. (Saunders, Philadelphia), 3rd Ed., pp. 1061-1074.
2. Philbrick, W. M., Wysolmcrski, J. J., Galbraith, S., Holt, E., Orloff, J. J., Yang, K. H., Vasavada, R. C., Weir, E. C., Broadus, A. E. & Stewart, A. F. (1996) Physiol. Rev. 76, 127-173.
3. Yang, K. H. & Stewart, A. F. (1996) in Principles of Bone Biology, eds. Bilezikian, J. P., Raisz, L. & Rodan, G. (Academic, San Diego), pp. 347-376.
4. Karaplis, A. C., Luz, A., Glowacki, J., Bronson, R. T., Tybulewicz, V. L. J., Kronenberg, H. M. & Mulligan, R. C. (1994) Genes Dev. 8, 277-289.
5. Deftos, L. J., Burton, D. W. & Brandt, D. W. (1993) J. Clin. Invest. 92, 727-735.
6. Plawner, L. L., Philbrick, W. M., Burtis, W. J., Broadus, A. E. & Stewart, A. F. (1995) J. Biol. Chem. 270, 14078-14084.
7. Wu, T., Vasavada, R., Yang, K., Massfelder, T., Ganz, M., Abbas, S. K., Care, A. D. & Stewart, A. F. (1996) J. Biol. Chem. 271, 24371-24381.
8. Segre, G. V. (1994) in The Parathyroids, eds. Bilezikian, J. P., Levine, M. A. & Marcus, R. (Raven, New York), pp. 213-229.
9. Orloff, J. J., Kats, Y., Urena, P., Schipani, E., Vasavada, R. C., Philbrick, W. M., Behal, A., Abou-Samra, A.-B., Segre, G. V. & Jüppner, H. (1995) Endocrinology 136, 3016-3023.
10. Orloff, J. J., Kats, Y., Nathanson, M. H., Moyer, S. M., Mitnick, M. A., et al. (1996) Endocrinology 137, 5376-5385.
11. Valin, A., Garcia-Ocana, A., De Miguel, F., Sarasa, J. L. & Esbrit, P. (1997) J. Cell Physiol. 170, 209-215.
12. Cornish, J., Callon, K. E., Nicholson, G. C. & Reid, I. R. (1997) Endocrinology 138, 1299-1304.
13. Kaiser, S. M., Laneuville, P., Bernier, S. M., Rhim, J. S., Kremer, R., et al. (1992) J. Biol. Chem. 267, 13623-13628.
14. Kaiser, S. M., Sebag, M., Rhim, J. S., Kremer, R. & Goltzman, D. (1994) Mol. Endocrinol. 8, 139-147.
15. Henderson, J. E., Amizuka, N., Warshawsky, H., Diasotto, D., Lanske, B. M. K., et al. (1995) Mol. Cell Biol. 15, 4064-4075.
16. Dingwall, C. & Laskey, R. (1991) Trends Biochem. Sci. 16, 478-481.
17. Massfelder, T., Helwig, J.-J. & Stewarl, A. F. (1996) Endocrinology 137, 3151-3153.
18. Nakayama, T., Ohtsuru, A., Enomoto, H., Namba, H., Ozeki, S., Shibata, Y., Yokota, T., Nohuyoshi, M., Ito, M., Sekine, I. & Yamashita, S. (1994) Biochem. Biophys. Res. Commun. 200, 1038-1045.
19. Pirola, C. J., Wang, H.-M., Kamyar, A., Wu, S., Enomoto, H., Sharifi, B., Forrester, J. S., Clemens, T. L. & Fagin, J. A. (1993) J. Biol. Chem. 286, 1987-1994.
20. Maeda, S., Wu, S., Juppner, H., Green, J., Aragay, A. M., Simon, M. I., Fagin, J. A. & Clemens, T. L. (1996) Endocrinology 137, 3154-3162.
21. Jiang, B., Morimoto, S., Fukuo, K., Yasuda, O., Chen, S. & Ogihara, T. (1995) Miner. Electrolyte Metab. 21, 157-160.
22. Stewart, A., Mangin, M., Wu, T., Goumas, D., Insogna, K. L., Burtis, W. J. & Broadus, A. E. (1988) J. Clin. Invest. 81, 596-600.
23. Kimes, B. W. & Brandt, B. L. (1976) Exp. Cell Res. 98, 349-366.
24. Yang, K. H., de Papp, A. E., Soifer, N. S., Wu, T. L., Porter, S. E., Bellantoni, M., Burtis, W. J., Broadus, A. E., Philbrick, W. M. & Stewart, A. F. (1994) Biochemistry 33, 7460-7469.
25. Burtis, W. J., Brady, T. G., Orloff, J. J., Ersbak, J. B., Warrell, R. P., Olson, B. R., Wu, T. L., Mitnick, M. A., Broadus, A. E. & Stewart, A. F. (1990) N. Engl. J. Med. 322, 1106-1112.
26. Wysolmerski, J. J., Broadus, A. E., Zhou, J., Fuchs, E., Milstone, L. M. & Philbrick, W. M. (1994) Proc. Natl. Acad. Sci. USA 91, 1133-1137.
27. Wysolmerski, J. J., McCaughern-Carucci, J. F., Daifotis, A. G., Broadus, A. E. & Philbrick, W. M. (1995) Development (Cambridge, U.K.) 121, 3539-3547.
28. Vasavada, R., Cavaliere, C., D'Ercole, A. J., Dann, P., Burtis, W. J., Madlener, A. L., Zawalich, K., Zawalich, W., Philbrick, W. M. & Stewart, A. F. (1996) J. Biol. Chem. 271, 1200-1208.
29. Ozeki, S., Ohtsuru, A., Seto, S., Takeshita, S., Yano, H., Nakayama, T., Ito, M., Yokota, T., Nobuyoshi, M., Segre, G., Yamashita, S. & Yano, K. (1996) Arteriosler. Thromb. Vasc. Biol. 16, 565-575.
30. Okano, K., Pirola, C. Wang, H.-M., Forrester, J., Fagin, J. & Clemens, T. (1995) Endocrinology 136, 1782-1789.
31. Hurley, M. & Florkiewicz, R. Z. (1996) in Principles of Bone Biology, eds. Raisz, L. R., Rodan, G. A. & Bilezikian, J. P. (Academic, New York), pp. 627-745.
32. Kiefer, P., Acland, P., Pappin, D., Peters, G. & Dickson, C. (1994) EMBO J. 13, 4126-4136.
33. Kiefer, P. & Dickson, C. (1995) Mol. Cell. Biol. 15, 4364-4374.
34. Ditmer, L. S., Burton, D. W. & Deftos, L. J. (1996) Endocrinology 137, 1608-1617.