Tissue-specific targeting of the Pthrp gene: The generation of mice with floxed alleles

Endocrinology

Volumn 142, Issue 5, 2001, Pages 2070-2077

  He, Bin ^a   Deckelbaum, Ron A ^a,b   Miao, Dengshun ^b   Lipman, Mark L ^a   Pollak, Michael ^a   Goltzman, David ^b   Karaplis, Andrew C ^a  

^a MCGILL UNIVERSITY   (Canada)

^b ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CRE RECOMBINASE; DNA; PARATHYROID HORMONE RELATED PROTEIN;

ALLELE; ARTICLE; DNA SEQUENCE; EXON; GENE; GENE DELETION; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOUTHERN BLOTTING; TRANSGENE;

EID: 0035043115     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.142.5.8146     Document Type: Article

References (22)

1. The physiology of parathyroid hormone-related protein: An emerging role as a developmental factor
2. Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene
3. Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation
4. Programmed cell death of chondrocytes and aberrant chondrogenesis in mice homozygous for parathyroid hormone-related peptide gene deletion
5. Haploin-sufficiency of parathyroid hormone-related peptide (PTHrP) results in abnormal postnatal bone development
6. Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development
7. Parathyroid hormone-related protein is required for tooth eruption
8. PTHrP regulates epidermal differentiation in adult mice
9. Parathyroid hormone-related protein protects against kainic acid excitotoxicity in rat cerebellar granule cells by regulating L-type channel calcium flux
10. Mechanism of strand cleavage and exchange in the Cre-lox site-specific recombination system
11. Z/AP, a double reporter for cre-mediated recombination
12. An effective reactivation of alkaline phosphatase in hard tissues completely decalcified for light and electron microscopy
13. Structure of the mouse gene encoding parathyroid hormone-related peptide
14. The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos
15. Analysis of Fgf8 gene function in vertebrate development
16. Site-specific recombinases: Tools for genome engineering
17. Engineering the mouse genome by site-specific recombination
18. Promoter traps in embryonic stem cells: A genetic screen to identify and mutate developmental genes in mice
19. Generalized lacZ expression with the ROSA26 Cre reporter strain
20. Deletion of a DNA polymerase β gene segment in T cells using cell type-specific gene targeting
21. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
22. A short amino acid sequence able to specify nuclear location