Inhibition of Rho kinases increases directional motility of microvascular endothelial cells

Biochemical Pharmacology

Volumn 83, Issue 5, 2012, Pages 616-626

  Breyer, Johannes ^a   Samarin, Jana ^a,b   Rehm, Margot ^a   Lautscham, Lena ^a   Fabry, Ben ^a   Goppelt Struebe, Margarete ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Actin cytoskeleton; Cell motility; Connective tissue growth factor; Microvascular endothelial cells; Rho kinase; ROCK2

Indexed keywords

COLLAGEN TYPE 1; F ACTIN; FIBRONECTIN; H 1152; RHO KINASE; RHO KINASE 2; RHO KINASE INHIBITOR; SLX 2119; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CONTACT; CELL MIGRATION; CELL MOTILITY; CYTOSKELETON; EXTRACELLULAR MATRIX; MICROVASCULAR ENDOTHELIAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SPHEROID CELL; WOUND HEALING;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; CELL ADHESION; CELL LINE; CELL MOVEMENT; COLLAGEN TYPE I; ENDOTHELIAL CELLS; MICE; MICE, KNOCKOUT; RHO-ASSOCIATED KINASES; RNA INTERFERENCE; TUBULIN; VINCULIN;

EID: 84856086010     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.12.012     Document Type: Article

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