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Volumn 13, Issue 1, 2012, Pages

Implications for health and disease in the genetic signature of the Ashkenazi Jewish population

Author keywords

[No Author keywords available]

Indexed keywords

ABCB1 GENE; AIF1 GENE; ALF1 GENE; ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; ASHKENAZI JEWISH POPULATION; AUTOIMMUNE DISEASE; CFTR GENE; CHLORIDE TRANSPORT; CLRN1 GENE; CONTROLLED STUDY; CYSTIC FIBROSIS; DISEASE PREDISPOSITION; DKK3 GENE; ETHNIC GROUP; FEMALE; GENE; GENE FREQUENCY; GENE FUNCTION; GENETIC DISTANCE; GEOGRAPHIC ORIGIN; GSTP1 GENE; HEALTH STATUS; HEXA GENE; HLA DRB GENE; HUMAN; HUMAN EXPERIMENT; IKB KAP GENE; LCT GENE; MALE; MC1R GENE; METABOLIC DISORDER; MHC CLASS 1 GENE; MTHFR GENE; NOD2 GENE; PCDH15 GENE; PER1 GENE; PLAU GENE; POPULATION DIFFERENTIATION; POPULATION GENETIC STRUCTURE; PPARG GENE; PPARGC1A GENE; SH2B3 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; ASIAN; CAUCASIAN; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETICS; JEW; POPULATION GENETICS; PRINCIPAL COMPONENT ANALYSIS;

EID: 84856084252     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/gb-2012-13-1-r2     Document Type: Article
Times cited : (44)

References (65)
  • 1
    • 57549090341 scopus 로고    scopus 로고
    • Accounting for ancestry: population substructure and genome-wide association studies.
    • 10.1093/hmg/ddn268, 2782357, 18852203
    • Tian C, Gregersen PK, Seldin MF. Accounting for ancestry: population substructure and genome-wide association studies. Hum Mol Genet 2008, 17:R143-R150. 10.1093/hmg/ddn268, 2782357, 18852203.
    • (2008) Hum Mol Genet , vol.17
    • Tian, C.1    Gregersen, P.K.2    Seldin, M.F.3
  • 2
    • 77953811255 scopus 로고    scopus 로고
    • New approaches to population stratification in genome-wide association studies.
    • 2975875, 20548291
    • Price AL, Zaitlen NA, Reich D, Patterson N. New approaches to population stratification in genome-wide association studies. Nat Rev Genet 2010, 11:459-463. 2975875, 20548291.
    • (2010) Nat Rev Genet , vol.11 , pp. 459-463
    • Price, A.L.1    Zaitlen, N.A.2    Reich, D.3    Patterson, N.4
  • 4
    • 70349472875 scopus 로고    scopus 로고
    • Reconstructing Indian population history.
    • 10.1038/nature08365, 2842210, 19779445
    • Reich D, Thangaraj K, Patterson N, Price AL, Singh L. Reconstructing Indian population history. Nature 2009, 461:489-494. 10.1038/nature08365, 2842210, 19779445.
    • (2009) Nature , vol.461 , pp. 489-494
    • Reich, D.1    Thangaraj, K.2    Patterson, N.3    Price, A.L.4    Singh, L.5
  • 6
    • 0034940158 scopus 로고    scopus 로고
    • The value of isolated populations.
    • 10.1038/91060, 11479587
    • Shifman S, Darvasi A. The value of isolated populations. Nat Genet 2001, 28:309-310. 10.1038/91060, 11479587.
    • (2001) Nat Genet , vol.28 , pp. 309-310
    • Shifman, S.1    Darvasi, A.2
  • 12
    • 77952983701 scopus 로고    scopus 로고
    • Ashkenazi Jewish screening in the twenty-first century.
    • 10.1016/j.ogc.2010.01.001, 20494256
    • Klugman S, Gross SJ. Ashkenazi Jewish screening in the twenty-first century. Obstet Gynecol Clin North Am 2010, 37:37-46. 10.1016/j.ogc.2010.01.001, 20494256.
    • (2010) Obstet Gynecol Clin North Am , vol.37 , pp. 37-46
    • Klugman, S.1    Gross, S.J.2
  • 13
    • 70449474155 scopus 로고    scopus 로고
    • The LRRK2 G2019S mutation as the cause of Parkinson's disease in Ashkenazi Jews.
    • 10.1007/s00702-009-0303-0, 19756366
    • Thaler A, Ash E, Gan-Or Z, Orr-Urtreger A, Giladi N. The LRRK2 G2019S mutation as the cause of Parkinson's disease in Ashkenazi Jews. J Neural Transm 2009, 116:1473-1482. 10.1007/s00702-009-0303-0, 19756366.
    • (2009) J Neural Transm , vol.116 , pp. 1473-1482
    • Thaler, A.1    Ash, E.2    Gan-Or, Z.3    Orr-Urtreger, A.4    Giladi, N.5
  • 14
    • 54849159000 scopus 로고    scopus 로고
    • Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer risk.
    • 10.1001/jama.300.13.1523, 2628475, 18827209
    • Kaklamani VG, Wisinski KB, Sadim M, Gulden C, Do A, Offit K, Baron JA, Ahsan H, Mantzoros C, Pasche B. Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer risk. JAMA 2008, 300:1523-1531. 10.1001/jama.300.13.1523, 2628475, 18827209.
    • (2008) JAMA , vol.300 , pp. 1523-1531
    • Kaklamani, V.G.1    Wisinski, K.B.2    Sadim, M.3    Gulden, C.4    Do, A.5    Offit, K.6    Baron, J.A.7    Ahsan, H.8    Mantzoros, C.9    Pasche, B.10
  • 15
    • 46949088755 scopus 로고    scopus 로고
    • Type 2 diabetes susceptibility loci in the Ashkenazi Jewish population.
    • 10.1007/s00439-008-0520-x, 18516622
    • Bronstein M, Pisanté A, Yakir B, Darvasi A. Type 2 diabetes susceptibility loci in the Ashkenazi Jewish population. Hum Genet 2008, 124:101-104. 10.1007/s00439-008-0520-x, 18516622.
    • (2008) Hum Genet , vol.124 , pp. 101-104
    • Bronstein, M.1    Pisanté, A.2    Yakir, B.3    Darvasi, A.4
  • 19
    • 0035514049 scopus 로고    scopus 로고
    • A genetic profile of contemporary Jewish populations.
    • Ostrer H. A genetic profile of contemporary Jewish populations. Nat Rev Genet 2001, 2:891-898.
    • (2001) Nat Rev Genet , vol.2 , pp. 891-898
    • Ostrer, H.1
  • 21
    • 60849097246 scopus 로고    scopus 로고
    • A genome-wide genetic signature of Jewish ancestry perfectly separates individuals with and without full Jewish ancestry in a large random sample of European Americans.
    • 10.1186/gb-2009-10-1-r7, 2687795, 19161619
    • Need AC, Kasperaviciute D, Cirulli ET, Goldstein DB. A genome-wide genetic signature of Jewish ancestry perfectly separates individuals with and without full Jewish ancestry in a large random sample of European Americans. Genome Biol 2009, 10:R7. 10.1186/gb-2009-10-1-r7, 2687795, 19161619.
    • (2009) Genome Biol , vol.10
    • Need, A.C.1    Kasperaviciute, D.2    Cirulli, E.T.3    Goldstein, D.B.4
  • 24
    • 77953231974 scopus 로고    scopus 로고
    • Abraham's children in the genome era: major Jewish diaspora populations comprise distinct genetic clusters with shared Middle Eastern ancestry.
    • 10.1016/j.ajhg.2010.04.015, 3032072, 20560205
    • Atzmon G, Hao L, Pe'er I, Velez C, Pearlman A, Palamara PF, Morrow B, Friedman E, Oddoux C, Burns E, Ostrer H. Abraham's children in the genome era: major Jewish diaspora populations comprise distinct genetic clusters with shared Middle Eastern ancestry. Am J Hum Genet 2010, 86:850-859. 10.1016/j.ajhg.2010.04.015, 3032072, 20560205.
    • (2010) Am J Hum Genet , vol.86 , pp. 850-859
    • Atzmon, G.1    Hao, L.2    Pe'er, I.3    Velez, C.4    Pearlman, A.5    Palamara, P.F.6    Morrow, B.7    Friedman, E.8    Oddoux, C.9    Burns, E.10    Ostrer, H.11
  • 25
    • 77957999545 scopus 로고    scopus 로고
    • Signatures of founder effects, admixture, and selection in the Ashkenazi Jewish population.
    • 10.1073/pnas.1004381107, 2941333, 20798349
    • Bray SM, Mulle JG, Dodd AF, Pulver AE, Wooding S, Warren ST. Signatures of founder effects, admixture, and selection in the Ashkenazi Jewish population. Proc Natl Acad Sci USA 2010, 107:16222-16227. 10.1073/pnas.1004381107, 2941333, 20798349.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 16222-16227
    • Bray, S.M.1    Mulle, J.G.2    Dodd, A.F.3    Pulver, A.E.4    Wooding, S.5    Warren, S.T.6
  • 26
    • 0026560940 scopus 로고
    • Cystic fibrosis mutations delta F508 and G542X in Jewish patients.
    • 10.1136/jmg.29.2.131, 1015854, 1377276
    • Lerer I, Sagi M, Cutting GR, Abeliovich D. Cystic fibrosis mutations delta F508 and G542X in Jewish patients. J Med Genet 1992, 29:131-133. 10.1136/jmg.29.2.131, 1015854, 1377276.
    • (1992) J Med Genet , vol.29 , pp. 131-133
    • Lerer, I.1    Sagi, M.2    Cutting, G.R.3    Abeliovich, D.4
  • 31
    • 0032822750 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase (MTHFR): the incidence of mutations C677T and A1298C in the Ashkenazi Jewish population.
    • 10.1002/(SICI)1096-8628(19991008)86:4<380::AID-AJMG13>3.0.CO;2-9, 10494095
    • Rady PL, Tyring SK, Hudnall SD, Vargas T, Kellner LH, Nitowsky H, Matalon RK. Methylenetetrahydrofolate reductase (MTHFR): the incidence of mutations C677T and A1298C in the Ashkenazi Jewish population. Am J Med Genet 1999, 86:380-384. 10.1002/(SICI)1096-8628(19991008)86:4<380::AID-AJMG13>3.0.CO;2-9, 10494095.
    • (1999) Am J Med Genet , vol.86 , pp. 380-384
    • Rady, P.L.1    Tyring, S.K.2    Hudnall, S.D.3    Vargas, T.4    Kellner, L.H.5    Nitowsky, H.6    Matalon, R.K.7
  • 34
    • 77949397703 scopus 로고    scopus 로고
    • The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis.
    • 10.1093/aje/kwp450, 2834889, 20179158
    • Gouda HN, Sagoo GS, Harding AH, Yates J, Sandhu MS, Higgins JP. The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis. Am J Epidemiol 2010, 171:645-655. 10.1093/aje/kwp450, 2834889, 20179158.
    • (2010) Am J Epidemiol , vol.171 , pp. 645-655
    • Gouda, H.N.1    Sagoo, G.S.2    Harding, A.H.3    Yates, J.4    Sandhu, M.S.5    Higgins, J.P.6
  • 38
    • 34447120188 scopus 로고    scopus 로고
    • HLA-DR15 haplotype and multiple sclerosis: a HuGE review.
    • 10.1093/aje/kwk118, 17329717
    • Schmidt H, Williamson D, Ashley-Koch A. HLA-DR15 haplotype and multiple sclerosis: a HuGE review. Am J Epidemiol 2007, 165:1097-1109. 10.1093/aje/kwk118, 17329717.
    • (2007) Am J Epidemiol , vol.165 , pp. 1097-1109
    • Schmidt, H.1    Williamson, D.2    Ashley-Koch, A.3
  • 41
    • 20144369614 scopus 로고    scopus 로고
    • Pathogen-riven selection and worldwide HLA class I diversity.
    • 10.1016/j.cub.2005.04.050, 15936272
    • Prugnolle F, Manica A, Charpentier M, Guégan JF, Guernier V, Balloux F. Pathogen-riven selection and worldwide HLA class I diversity. Curr Biol 2005, 15:1022-1027. 10.1016/j.cub.2005.04.050, 15936272.
    • (2005) Curr Biol , vol.15 , pp. 1022-1027
    • Prugnolle, F.1    Manica, A.2    Charpentier, M.3    Guégan, J.F.4    Guernier, V.5    Balloux, F.6
  • 42
    • 67650709487 scopus 로고    scopus 로고
    • Recent advances in the genetics of autoimmune disease.
    • 10.1146/annurev.immunol.021908.132653, 2992886, 19302045
    • Gregersen PK, Olsson LM. Recent advances in the genetics of autoimmune disease. Annu Rev Immunol 2009, 27:363-391. 10.1146/annurev.immunol.021908.132653, 2992886, 19302045.
    • (2009) Annu Rev Immunol , vol.27 , pp. 363-391
    • Gregersen, P.K.1    Olsson, L.M.2
  • 43
    • 0031455420 scopus 로고    scopus 로고
    • Identical MHC markers in non-Jewish Iranian and Ashkenazi Jewish patients with pemphigus vulgaris: possible common central Asian ancestral origin.
    • 10.1016/S0198-8859(97)00182-1, 9438197
    • Mobini N, Yunis EJ, Alper CA, Yunis JJ, Delgado JC, Yunis DE, Firooz A, Dowlati Y, Bahar K, Gregersen PK, Ahmed AR. Identical MHC markers in non-Jewish Iranian and Ashkenazi Jewish patients with pemphigus vulgaris: possible common central Asian ancestral origin. Hum Immunol 1997, 57:62-67. 10.1016/S0198-8859(97)00182-1, 9438197.
    • (1997) Hum Immunol , vol.57 , pp. 62-67
    • Mobini, N.1    Yunis, E.J.2    Alper, C.A.3    Yunis, J.J.4    Delgado, J.C.5    Yunis, D.E.6    Firooz, A.7    Dowlati, Y.8    Bahar, K.9    Gregersen, P.K.10    Ahmed, A.R.11
  • 46
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder.
    • International Schizophrenia Consortium
    • Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Sklar P. International Schizophrenia Consortium Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009, 460:748-752. International Schizophrenia Consortium.
    • (2009) Nature , vol.460 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3    Visscher, P.M.4    O'Donovan, M.C.5    Sullivan, P.F.6    Sklar, P.7
  • 47
    • 0031292686 scopus 로고    scopus 로고
    • Cystic fibrosis in Jews: frequency and mutation distribution.
    • Kerem B, Chiba-Falek O, Kerem E. Cystic fibrosis in Jews: frequency and mutation distribution. Genet Test 1997, 1:35-39.
    • (1997) Genet Test , vol.1 , pp. 35-39
    • Kerem, B.1    Chiba-Falek, O.2    Kerem, E.3
  • 48
    • 0036897460 scopus 로고    scopus 로고
    • Variation at NOD2/CARD15 in familial and sporadic cases of Crohn's disease in the Ashkenazi Jewish population.
    • 10.1111/j.1572-0241.2002.07105.x, 12492195
    • Zhou Z, Lin XY, Akolkar PN, Gulwani-Akolkar B, Levine J, Katz S, Silver J. Variation at NOD2/CARD15 in familial and sporadic cases of Crohn's disease in the Ashkenazi Jewish population. Am J Gastroenterol 2002, 97:3095-3101. 10.1111/j.1572-0241.2002.07105.x, 12492195.
    • (2002) Am J Gastroenterol , vol.97 , pp. 3095-3101
    • Zhou, Z.1    Lin, X.Y.2    Akolkar, P.N.3    Gulwani-Akolkar, B.4    Levine, J.5    Katz, S.6    Silver, J.7
  • 52
    • 69749099417 scopus 로고    scopus 로고
    • Fast model-based estimation of ancestry in unrelated individuals.
    • 10.1101/gr.094052.109, 2752134, 19648217
    • Alexander DH, Novembre J, Lange K. Fast model-based estimation of ancestry in unrelated individuals. Genome Res 2009, 19:1655-1664. 10.1101/gr.094052.109, 2752134, 19648217.
    • (2009) Genome Res , vol.19 , pp. 1655-1664
    • Alexander, D.H.1    Novembre, J.2    Lange, K.3
  • 53
    • 17644402806 scopus 로고    scopus 로고
    • Estimation of individual admixture: analytical and study design considerations.
    • 10.1002/gepi.20064, 15712363
    • Tang H, Peng J, Wang P, Risch NJ. Estimation of individual admixture: analytical and study design considerations. Genet Epidemiol 2005, 28:289-301. 10.1002/gepi.20064, 15712363.
    • (2005) Genet Epidemiol , vol.28 , pp. 289-301
    • Tang, H.1    Peng, J.2    Wang, P.3    Risch, N.J.4
  • 54
    • 1342331102 scopus 로고    scopus 로고
    • DISTRUCT: a program for the graphical display of population structure.
    • Rosenberg NA. DISTRUCT: a program for the graphical display of population structure. Mol Ecol Notes 2004, 4:137-138.
    • (2004) Mol Ecol Notes , vol.4 , pp. 137-138
    • Rosenberg, N.A.1
  • 55
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies.
    • 10.1038/ng1847, 16862161
    • Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006, 38:904-909. 10.1038/ng1847, 16862161.
    • (2006) Nat Genet , vol.38 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5    Reich, D.6
  • 56
    • 36849080837 scopus 로고    scopus 로고
    • Genepop'007: a complete re-implementation of the genepop software for Windows and Linux.
    • 10.1111/j.1471-8286.2007.01931.x, 21585727
    • Rousset F. genepop'007: a complete re-implementation of the genepop software for Windows and Linux. Mol Ecol Resour 2008, 8:103-106. 10.1111/j.1471-8286.2007.01931.x, 21585727.
    • (2008) Mol Ecol Resour , vol.8 , pp. 103-106
    • Rousset, F.1
  • 57
    • 0021566877 scopus 로고
    • Estimating F-statistics for the analysis of population structure.
    • Weir BS, Cockerham CC. Estimating F-statistics for the analysis of population structure. Evolution 1984, 38:1358-1370.
    • (1984) Evolution , vol.38 , pp. 1358-1370
    • Weir, B.S.1    Cockerham, C.C.2
  • 58
    • 0029178096 scopus 로고
    • An exact test for population differentiation.
    • Raymond M, Rousset F. An exact test for population differentiation. Evolution 1995, 49:1283-1286.
    • (1995) Evolution , vol.49 , pp. 1283-1286
    • Raymond, M.1    Rousset, F.2
  • 59
    • 67649584052 scopus 로고    scopus 로고
    • Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder.
    • 10.1016/j.ajhg.2009.05.011, 2706963, 19539887, Wellcome Trust Case-Control Consortium
    • Holmans P, Green EK, Pahwa JS, Ferreira MA, Purcell SM, Sklar P, , Owen MJ, O'Donovan MC, Craddock N. Wellcome Trust Case-Control Consortium Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Hum Genet 2009, 85:13-24. 10.1016/j.ajhg.2009.05.011, 2706963, 19539887, Wellcome Trust Case-Control Consortium.
    • (2009) Am J Hum Genet , vol.85 , pp. 13-24
    • Holmans, P.1    Green, E.K.2    Pahwa, J.S.3    Ferreira, M.A.4    Purcell, S.M.5    Sklar, P.6    Owen, M.J.7    O'Donovan, M.C.8    Craddock, N.9
  • 60
    • 0038005018 scopus 로고    scopus 로고
    • DAVID: Database for Annotation, Visualization, and Integrated Discovery.
    • 10.1186/gb-2003-4-5-p3, 12734009
    • Dennis G, Sherman BT, Hosack DA, Yang J, Gao W, Lane HC, Lempicki RA. DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol 2003, 4:P3. 10.1186/gb-2003-4-5-p3, 12734009.
    • (2003) Genome Biol , vol.4
    • Dennis, G.1    Sherman, B.T.2    Hosack, D.A.3    Yang, J.4    Gao, W.5    Lane, H.C.6    Lempicki, R.A.7
  • 61
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder.
    • International Schizophrenia Consortium
    • Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Sklar P. International Schizophrenia Consortium Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 2009, 460:748-752. International Schizophrenia Consortium.
    • (2009) Nature , vol.460 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3    Visscher, P.M.4    O'Donovan, M.C.5    Sullivan, P.F.6    Sklar, P.7
  • 63
    • 78549251736 scopus 로고    scopus 로고
    • Analysing biological pathways in genome-wide association studies.
    • 10.1038/nrg2884, 21085203
    • Wang K, Li M, Hakonarson H. Analysing biological pathways in genome-wide association studies. Nat Rev Genet 2010, 11:843-854. 10.1038/nrg2884, 21085203.
    • (2010) Nat Rev Genet , vol.11 , pp. 843-854
    • Wang, K.1    Li, M.2    Hakonarson, H.3
  • 64
    • 77958486255 scopus 로고    scopus 로고
    • Statistical methods for pathway analysis of genome-wide data for association with complex genetic traits.
    • Holmans P. Statistical methods for pathway analysis of genome-wide data for association with complex genetic traits. Adv Genet 2010, 72:141-179.
    • (2010) Adv Genet , vol.72 , pp. 141-179
    • Holmans, P.1
  • 65
    • 77954300600 scopus 로고    scopus 로고
    • GSA-SNP: a general approach for gene set analysis of polymorphisms.
    • 10.1093/nar/gkq428, 2896081, 20501604
    • Nam D, Kim J, Kim SY, Kim S. GSA-SNP: a general approach for gene set analysis of polymorphisms. Nucleic Acids Res 2010, 38:W749-54. 10.1093/nar/gkq428, 2896081, 20501604.
    • (2010) Nucleic Acids Res , vol.38
    • Nam, D.1    Kim, J.2    Kim, S.Y.3    Kim, S.4


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