메뉴 건너뛰기




Volumn 30, Issue 2, 2012, Pages 100-107

Concise review: Limbal epithelial stem cells: Role of the niche microenvironment

Author keywords

Cornea; Extracellular matrix; Integrins; Stem cell microenvironment interactions

Indexed keywords

CELL MARKER; INTEGRIN RECEPTOR; SCLEROPROTEIN; TRANSCRIPTION FACTOR PAX6; DIFFERENTIATION ANTIGEN; INTEGRIN;

EID: 84856082805     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.794     Document Type: Review
Times cited : (103)

References (83)
  • 2
    • 34547955893 scopus 로고    scopus 로고
    • Transplantation of Ex Vivo Cultured Limbal Epithelial Stem Cells: A Review of Techniques and Clinical Results
    • DOI 10.1016/j.survophthal.2007.06.013, PII S0039625707001361
    • Shortt AJ, Secker GA, Notara MD et al. Transplantation of ex vivo cultured limbal epithelial stem cells: A review of techniques and clinical results. Surv Ophthalmol 2007;52:483-502. (Pubitemid 47268554)
    • (2007) Survey of Ophthalmology , vol.52 , Issue.5 , pp. 483-502
    • Shortt, A.J.1    Secker, G.A.2    Notara, M.D.3    Limb, G.A.4    Khaw, P.T.5    Tuft, S.J.6    Daniels, J.T.7
  • 3
    • 62249105621 scopus 로고    scopus 로고
    • Characterisation of the corneal surface in limbal stem cell deficiency and after transplantation of cultivated limbal epithelium
    • Pauklin M, Steuhl K, Meller D. Characterisation of the corneal surface in limbal stem cell deficiency and after transplantation of cultivated limbal epithelium. Ophthalmology 2009;116:1048-1056.
    • (2009) Ophthalmology , vol.116 , pp. 1048-1056
    • Pauklin, M.1    Steuhl, K.2    Meller, D.3
  • 4
    • 33748956316 scopus 로고    scopus 로고
    • Transplantation of Autologous Serum-Derived Cultivated Corneal Epithelial Equivalents for the Treatment of Severe Ocular Surface Disease
    • DOI 10.1016/j.ophtha.2006.04.030, PII S0161642006006907
    • Nakamura T, Inatomi T, Sotozono C et al. Transplantation of autologous serum-derived cultivated corneal epithelial equivalents for the treatment of severe ocular surface disease. Ophthalmology 2006;113: 1765-1772. (Pubitemid 44442442)
    • (2006) Ophthalmology , vol.113 , Issue.10 , pp. 1765-1772
    • Nakamura, T.1    Inatomi, T.2    Sotozono, C.3    Ang, L.P.K.4    Koizumi, N.5    Yokoi, N.6    Kinoshita, S.7
  • 5
    • 0037372076 scopus 로고    scopus 로고
    • Phenotypic study of a case receiving a keratolimbal allograft and amniotic membrane for total limbal stem cell deficiency
    • DOI 10.1016/S0161-6420(02)01764-5
    • Espana EM, Grueterich M, Ti SE et al. Phenotypic study of a case receiving a keratolimbal allograft and amniotic membrane for total limbal stem cell deficiency. Ophthalmology 2003;110:481-486. (Pubitemid 36262728)
    • (2003) Ophthalmology , vol.110 , Issue.3 , pp. 481-486
    • Espana, E.M.1    Grueterich, M.2    Ti, S.E.3    Tseng, S.C.G.4
  • 6
    • 67649616499 scopus 로고    scopus 로고
    • A contact lens-based technique for expansion and transplantation of autologous epithelial progenitors for ocular surface reconstruction
    • Di Girolamo N, Bosch M, Zamora K et al. A contact lens-based technique for expansion and transplantation of autologous epithelial progenitors for ocular surface reconstruction. Transplantation 2009;87: 1571-1578.
    • (2009) Transplantation , vol.87 , pp. 1571-1578
    • Di Girolamo, N.1    Bosch, M.2    Zamora, K.3
  • 7
    • 77950949984 scopus 로고    scopus 로고
    • Stem cell therapies for ocular surface disease
    • Ahmad S, Kolli S, Lako MM et al. Stem cell therapies for ocular surface disease. Drug Discov Today 2010;15:306-313.
    • (2010) Drug Discov Today , vol.15 , pp. 306-313
    • Ahmad, S.1    Kolli, S.2    Lako, M.M.3
  • 8
    • 0015231945 scopus 로고
    • Role of the pericorneal papillary structure in renewal of corneal epithelium
    • Davanger M, Evensen A. Role of the pericorneal papillary structure in renewal of corneal epithelium. Nature 1971;229:560-561.
    • (1971) Nature , vol.229 , pp. 560-561
    • Davanger, M.1    Evensen, A.2
  • 9
    • 80052375565 scopus 로고    scopus 로고
    • Wnt/b-catenin signalling regulates proliferation of human cornea epithelial stem/progenitor cells
    • Nakatsu MN, Ding Z, Ng MY et al. Wnt/b-catenin signalling regulates proliferation of human cornea epithelial stem/progenitor cells. Invest Ophthalmol Vis Sci 2011;52:4734-4741.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 4734-4741
    • Nakatsu, M.N.1    Ding, Z.2    Ng, M.Y.3
  • 10
    • 0038010517 scopus 로고    scopus 로고
    • Requirement for Pax6 in corneal morphogenesis: A role in adhesion
    • Davis J, Duncan MK, Robison WG et al. Requirement for Pax6 in corneal morphogenesis: A role in adhesion. J Cell Sci 2003;116:2157- 2167.
    • (2003) J Cell Sci , vol.116 , pp. 2157-2167
    • Davis, J.1    Duncan, M.K.2    Robison, W.G.3
  • 11
    • 14844307626 scopus 로고    scopus 로고
    • The corneal epithelial stem cell niche
    • Stepp MA, Zieske JD. The corneal epithelial stem cell niche. Ocul Surf 2005;3:15-26. (Pubitemid 40347577)
    • (2005) Ocular Surface , vol.3 , Issue.1 , pp. 15-26
    • Stepp, M.A.1    Zieske, J.D.2
  • 12
    • 0020842662 scopus 로고
    • The X, Y, Z hypothesis of corneal epithelial maintenance
    • Thoft RA, Friend J. The X, Y, Z hypothesis of corneal epithelial maintenance. Invest Ophthalmol Vis Sci 1983;24:1442-1443.
    • (1983) Invest Ophthalmol Vis Sci , vol.24 , pp. 1442-1443
    • Thoft, R.A.1    Friend, J.2
  • 13
    • 2142652984 scopus 로고    scopus 로고
    • Corneal development, limbal stem cell function, and corneal epithelial cell
    • Collinson JM, Chanas SA, Hill RE et al. Corneal development, limbal stem cell function, and corneal epithelial cell. Invest Ophthalmol Vis Sci 2004;45:1101-1108.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 1101-1108
    • Collinson, J.M.1    Chanas, S.A.2    Hill, R.E.3
  • 14
    • 0024523084 scopus 로고
    • Limbal autograft transplantation for ocular surface disorders
    • Kenyon KR, Tseng SC. Limbal autograft transplantation for ocular surface disorders. Ophthalmology 1989;96:709-722.
    • (1989) Ophthalmology , vol.96 , pp. 709-722
    • Kenyon, K.R.1    Tseng, S.C.2
  • 15
    • 0018102359 scopus 로고
    • The relationship between the spleen colony-forming cell and the haemopoietic stem cell. A hypothesis
    • Schofield R. The relationship between the spleen colony forming cell and the haemopoietic stem cell. Blood Cells 1978;4:7-25. (Pubitemid 8376317)
    • (1978) Blood Cells , vol.4 , Issue.1-2 , pp. 7-25
    • Schofield, R.1
  • 16
    • 80052335907 scopus 로고    scopus 로고
    • Epithelial transition zones: Merging microenvironments, niches, and cellular transformation
    • McNairn AJ, Guasch G. Epithelial transition zones: Merging microenvironments, niches, and cellular transformation. Eur J Dermatol 2011;21:21-28.
    • (2011) Eur J Dermatol , vol.21 , pp. 21-28
    • McNairn, A.J.1    Guasch, G.2
  • 17
    • 33745635043 scopus 로고    scopus 로고
    • The stem-cell niche as an entity of action
    • DOI 10.1038/nature04957, PII N04957
    • Scadden DT. The stem-cell niche as an entity of action. Nature 2006; 441:1075-1079. (Pubitemid 43990719)
    • (2006) Nature , vol.441 , Issue.7097 , pp. 1075-1079
    • Scadden, D.T.1
  • 18
    • 37549069749 scopus 로고    scopus 로고
    • No place like home: Anatomy and function of the stem cell niche
    • Jones DL, Wagers AJ. No place like home: Anatomy and function of the stem cell niche. Nature 2008;9:11-21.
    • (2008) Nature , vol.9 , pp. 11-21
    • Jones, D.L.1    Wagers, A.J.2
  • 19
    • 77957662326 scopus 로고    scopus 로고
    • IL6 and the human limbal stem cell niche: A mediator of epithelial-stromal interaction
    • Notara M, Shortt AJ, Galatowicz G et al. IL6 and the human limbal stem cell niche: A mediator of epithelial-stromal interaction. Stem Cell Res 2010;5:188-200.
    • (2010) Stem Cell Res , vol.5 , pp. 188-200
    • Notara, M.1    Shortt, A.J.2    Galatowicz, G.3
  • 20
    • 0024523631 scopus 로고
    • Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells
    • DOI 10.1016/0092-8674(89)90958-6
    • Cotsarelis G, Cheng S, Dong G et al. Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implication on epithelial stem cell. Cell 1989;57:201-209. (Pubitemid 19112360)
    • (1989) Cell , vol.57 , Issue.2 , pp. 201-209
    • Cotsarelis, G.1    Cheng, S.-Z.2    Dong, G.3    Sun, T.-T.4    Lavker, R.M.5
  • 21
    • 0028213637 scopus 로고
    • Slowly cycling (label-retaining) epidermal cells behave like clonogenic stem cells in vitro
    • Morris RJ, Potten CS. Slowly cycling (label-retaining) epidermal cells behave like clonogenic stem cells in vitro. Cell Prolif 1994;27:279- 289.
    • (1994) Cell Prolif , vol.27 , pp. 279-289
    • Morris, R.J.1    Potten, C.S.2
  • 22
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • Zhang J, Niu C, Ye L et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003;425:836- 841.
    • (2003) Nature , vol.425 , pp. 836-841
    • Zhang, J.1    Niu, C.2    Ye, L.3
  • 23
    • 0242268524 scopus 로고    scopus 로고
    • Osteoblastic cells regulate the haematopoietic stem cell niche
    • Calvi LM, Adams GB, Weibrecht KW et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 2003;425:841- 846.
    • (2003) Nature , vol.425 , pp. 841-846
    • Calvi, L.M.1    Adams, G.B.2    Weibrecht, K.W.3
  • 25
    • 0034551745 scopus 로고    scopus 로고
    • Hematopoietic stem cells express Tie-2 receptor in the murine fetal liver
    • Hsu HC, Ema H, Osawa M et al. Hematopoietic stem cells express Tie-2 receptor in the murine fetal liver. Blood 2000;96:3757-3762.
    • (2000) Blood , vol.96 , pp. 3757-3762
    • Hsu, H.C.1    Ema, H.2    Osawa, M.3
  • 26
    • 60149099498 scopus 로고    scopus 로고
    • Mosaic analysis of stem cell function and wound healing in the mouse corneal epithelium
    • Mort RL, Ramaesh T, Kleinjan DA et al. Mosaic analysis of stem cell function and wound healing in the mouse corneal epithelium. BMC Dev Biol 2009;9:4.
    • (2009) BMC Dev Biol , vol.9 , pp. 4
    • Mort, R.L.1    Ramaesh, T.2    Kleinjan, D.A.3
  • 28
    • 79955045966 scopus 로고    scopus 로고
    • Tissue regenerating, vision-restoring corneal epithelial stem cells
    • Echevarria TE, Di Girolamo N. Tissue regenerating, vision-restoring corneal epithelial stem cells. Stem Cell Rev 2011;2:256-268.
    • (2011) Stem Cell Rev , vol.2 , pp. 256-268
    • Echevarria, T.E.1    Di Girolamo, N.2
  • 29
    • 23944433665 scopus 로고    scopus 로고
    • Identification and characterization of limbal stem cells
    • DOI 10.1016/j.exer.2005.02.016, PII S0014483505000801
    • Schlotzer-Schrehardt U, Kruse FE. Identification and characterization of limbal stem cells. Exp Eye Res 2005;81:247-264. (Pubitemid 41208160)
    • (2005) Experimental Eye Research , vol.81 , Issue.3 , pp. 247-264
    • Schlotzer-Schrehardt, U.1    Kruse, F.E.2
  • 31
    • 0028941024 scopus 로고
    • Human corneal basement membrane heterogeneity: Topographical differences in the expression of type IV collagen and laminin isoforms
    • Ljubimov AV, Burgeson RE, Butkowski RJ et al. Human corneal basement membrane heterogeneity: Topographical differences in the expression of type IV collagen and laminin isoforms. Lab Invest 1995;72:461-473.
    • (1995) Lab Invest , vol.72 , pp. 461-473
    • Ljubimov, A.V.1    Burgeson, R.E.2    Butkowski, R.J.3
  • 35
    • 34547093396 scopus 로고    scopus 로고
    • Characterization of the limbal epithelial stem cell niche: Novel imaging techniques permit in vivo observation and targeted biopsy of limbal epithelial stem cells
    • DOI 10.1634/stemcells.2006-0580
    • Shortt AJ, Secker GA, Munro PM et al. Characterization of the limbal epithelial stem cell niche: Novel imaging techniques permit in vivo observation and targeted biopsy of limbal epithelial stem cells. Stem Cells 2007;25:1402-1409. (Pubitemid 47106007)
    • (2007) Stem Cells , vol.25 , Issue.6 , pp. 1402-1409
    • Shortt, A.J.1    Secker, G.A.2    Munro, P.M.3    Khaw, P.T.4    Tuft, S.J.5    Daniels, J.T.6
  • 36
    • 58149522237 scopus 로고    scopus 로고
    • Localization of the low-affinity nerve growth factor receptor p75 in human limbal epithelial cells
    • Di Girolamo N, Sarris M, Chui J et al. Localization of the low-affinity nerve growth factor receptor p75 in human limbal epithelial cells. J Cell Mol Med 2008;12:2799-2811.
    • (2008) J Cell Mol Med , vol.12 , pp. 2799-2811
    • Di Girolamo, N.1    Sarris, M.2    Chui, J.3
  • 37
    • 78650544439 scopus 로고    scopus 로고
    • Challenges to the study of asymmetric division in corneal and limbal epithelia
    • Castro-Munozledo F, Gomez-Flores E. Challenges to the study of asymmetric division in corneal and limbal epithelia. Exp Eye Res 2011;92:4-9.
    • (2011) Exp Eye Res , vol.92 , pp. 4-9
    • Castro-Munozledo, F.1    Gomez-Flores, E.2
  • 38
    • 0025313294 scopus 로고
    • Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
    • Costarelis G, Sun T, Lavker RM. Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 1990;61:1329-1337.
    • (1990) Cell , vol.61 , pp. 1329-1337
    • Costarelis, G.1    Sun, T.2    Lavker, R.M.3
  • 39
    • 24644494270 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote stratification and differentiation of mammalian skin
    • DOI 10.1038/nature03922
    • Lechler T, Fuchs E. Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature 2005;437:275-280. (Pubitemid 41294492)
    • (2005) Nature , vol.437 , Issue.7056 , pp. 275-280
    • Lechler, T.1    Fuchs, E.2
  • 41
    • 33746865602 scopus 로고    scopus 로고
    • Cell size correlates with phenotype and proliferative capacity in human corneal epithelial cells
    • DOI 10.1634/stemcells.2005-0148
    • De Paiva CS, Pflugfelder SC, Li DQ. Cell size correlates with phenotype and proliferative capacity in human corneal epithelial cells. Stem Cells 2006;24:368-375. (Pubitemid 44464806)
    • (2006) Stem Cells , vol.24 , Issue.2 , pp. 368-375
    • De Paiva, C.S.1    Pflugfelder, S.C.2    Li, D.-Q.3
  • 42
    • 0022470546 scopus 로고
    • Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells
    • Schermer A, Galvin S, Sun T. Differentiation-related expression of major 64K corneal kertain in vivo and in culture suggests limbal location of corneal epithelial stem cells. J Cell Biol 1986;103:49-62. (Pubitemid 16066991)
    • (1986) Journal of Cell Biology , vol.103 , Issue.1 , pp. 49-62
    • Schermer, A.1    Galvin, S.2    Sun, T.-T.3
  • 43
    • 12144274468 scopus 로고    scopus 로고
    • ABCG2 transporter identifies a population of clonogenic human limbal epithelial cells
    • DOI 10.1634/stemcells.2004-0093
    • De Paiva CS, Chen Z, Corrales RM et al. ABCG2 transporter identifies a population of clonogenic human limbal epithelial cells. Stem Cells 2005;23:63-73. (Pubitemid 40105292)
    • (2005) Stem Cells , vol.23 , Issue.1 , pp. 63-73
    • De Paiva, C.S.1    Chen, Z.2    Corrales, R.M.3    Pflugfelder, S.C.4    Li, D.-Q.5
  • 44
    • 79956049848 scopus 로고    scopus 로고
    • The anti-oxidative role of ABCG2 in corneal epithelial cells
    • Kubota M, Shimmura S, Miyashita H et al. The anti-oxidative role of ABCG2 in corneal epithelial cells. Invest Ophthalmol Vis Sci 2010; 51:5617-5622.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 5617-5622
    • Kubota, M.1    Shimmura, S.2    Miyashita, H.3
  • 47
    • 0036154828 scopus 로고    scopus 로고
    • The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells
    • Kim M, Turnquist H, Jackson J. The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoescht 33342 and is overexpressed in hematopoietic stem cells. Clin Cancer Res 2002;8:22-28. (Pubitemid 34101455)
    • (2002) Clinical Cancer Research , vol.8 , Issue.1 , pp. 22-28
    • Kim, M.1    Turnquist, H.2    Jackson, J.3    Sgagias, M.4    Yan, Y.5    Gong, M.6    Dean, M.7    Sharp, J.G.8    Cowan, K.9
  • 50
    • 70349575019 scopus 로고    scopus 로고
    • N-cadherin in the maintenance of human corneal limbal epithelial progenitor cells in vitro
    • Higa K, Shimmura S, Miyashita H et al. N-cadherin in the maintenance of human corneal limbal epithelial progenitor cells in vitro. Invest Ophthalmol Vis Sci 2009;50:4640-4645.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 4640-4645
    • Higa, K.1    Shimmura, S.2    Miyashita, H.3
  • 51
    • 0035930669 scopus 로고    scopus 로고
    • Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue
    • DOI 10.1126/science.1066707
    • Kiger AA, Jones L, Schulz C et al. Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue. Science 2001;294:2542-2545. (Pubitemid 34027293)
    • (2001) Science , vol.294 , Issue.5551 , pp. 2542-2545
    • Kiger, A.A.1    Jones, D.L.2    Schulz, C.3    Rogers, M.B.4    Fuller, M.T.5
  • 52
    • 0023202097 scopus 로고
    • Suprabasal expression of a 64-kilodalton keratin (no. 3) in developing human corneal epithelium
    • Rodrigues M, Ben-Zvi A, Krachmer J et al. Suprabasal expression of 64-kilodalton keratin (no. 3) in developing human corneal epithelium. Differentiation 1987;34:60-67. (Pubitemid 17112051)
    • (1987) Differentiation , vol.34 , Issue.1 , pp. 60-67
    • Rodrigues, M.1    Ben-Zvi, A.2    Krachmer, J.3
  • 53
    • 0028900002 scopus 로고
    • Three patterns of cytokine expression potentially involved in epithelial fibroblast interactions of human ocular surface
    • Li DQ, Tseng SCG. Three patterns of cytokine expression potentially involved in epithelial fibroblast interactions of human ocular surface. J Cell Physiol 1995;163:61-79.
    • (1995) J Cell Physiol , vol.163 , pp. 61-79
    • Li, D.Q.1    Tseng, S.C.G.2
  • 54
    • 79952838326 scopus 로고    scopus 로고
    • Limbal fibroblast conditioned media: A non-invasive treatment for limbal stem cell deficiency
    • Amirjamshidi H, Milani BY, Sagha HM et al. Limbal fibroblast conditioned media: A non-invasive treatment for limbal stem cell deficiency. Mol Vis 2011;17:658-666.
    • (2011) Mol Vis , vol.17 , pp. 658-666
    • Amirjamshidi, H.1    Milani, B.Y.2    Sagha, H.M.3
  • 55
    • 78650541971 scopus 로고    scopus 로고
    • Effects of fibroblast origin and phenotype on the proliferative potential of limbal epithelial progenitors
    • Ainscough SL, Barnard Z, Schwab IR et al. Effects of fibroblast origin and phenotype on the proliferative potential of limbal epithelial progenitors. Exp Eye Res 2011;92:10-19.
    • (2011) Exp Eye Res , vol.92 , pp. 10-19
    • Ainscough, S.L.1    Barnard, Z.2    Schwab, I.R.3
  • 56
    • 77956755675 scopus 로고    scopus 로고
    • Basement membrane components are key players in specialized extracellular matrices
    • Kruegel J, Miosge N. Basement membrane components are key players in specialized extracellular matrices. Cell Mol Life Sci 2010;67: 2879-2895.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 2879-2895
    • Kruegel, J.1    Miosge, N.2
  • 58
    • 3042582129 scopus 로고    scopus 로고
    • Transdifferentiation of corneal epithelium: Evidence for a linkage between the segregation of epidermal stem cells and the induction of hair follicles during embryogenesis
    • DOI 10.1387/ijdb.15272385, Skin Development
    • Pearton DJ, Ferraris C, Dhouailly D. Transdifferentiation of corneal epithelium: Evidence for a linkage between the segregation of epidermal stem cells and the induction of hair follicles during embryogenesis. Int J Dev Biol 2004;48:197-201. (Pubitemid 38807934)
    • (2004) International Journal of Developmental Biology , vol.48 , Issue.2-3 , pp. 197-201
    • Pearton, D.J.1    Ferraris, C.2    Dhouailly, D.3
  • 59
    • 65249163546 scopus 로고    scopus 로고
    • Corneal limbal microenvironment can induce transdifferentiation of hair follicle stem cells into corneal epithelial-like cells
    • Blazejewska EA, Schlotzer-Schrehardt U, Zenkel M et al. Corneal limbal microenvironment can induce transdifferentiation of hair follicle stem cells into corneal epithelial-like cells. Stem Cells 2009;27: 642-652.
    • (2009) Stem Cells , vol.27 , pp. 642-652
    • Blazejewska, E.A.1    Schlotzer-Schrehardt, U.2    Zenkel, M.3
  • 60
    • 0029930491 scopus 로고    scopus 로고
    • The immunohistochemical composition of the human corneal basement membrane
    • DOI 10.1097/00003226-199605000-00010
    • Tuori A, Uusitalo H, Burgeson RE et al. The immunohistochemical composition of the human corneal basement membrane. Cornea 1996; 15:286-294. (Pubitemid 26123068)
    • (1996) Cornea , vol.15 , Issue.3 , pp. 286-294
    • Tuori, A.1    Uusitalo, H.2    Burgeson, R.E.3    Terttunen, J.4    Virtanen, I.5
  • 61
    • 0025644744 scopus 로고
    • Absence of type IV collagen in the centre of the corneal epithelial basement membrane
    • Cleutjens JPM, Havenith MG, Kasper M et al. Absence of type IV collagen in the centre of the corneal epithelial basement membrane. Histochem J 1990;22:688-694.
    • (1990) Histochem J , vol.22 , pp. 688-694
    • Cleutjens, J.P.M.1    Havenith, M.G.2    Kasper, M.3
  • 62
    • 0033653002 scopus 로고    scopus 로고
    • Developmental changes in patterns of expression of tenascin-C variants in the human cornea
    • Maseruka H, Ridgway A, Tullo A et al. Developmental changes in patterns of expression of tenascin-C variants in the human cornea. Invest Ophthalmol Vis Sci 2000;41:4101-4107.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 4101-4107
    • Maseruka, H.1    Ridgway, A.2    Tullo, A.3
  • 63
    • 72849131611 scopus 로고    scopus 로고
    • Stem cell activity in the developing human cornea
    • Davies SB, Chui J, Madigan MC et al. Stem cell activity in the developing human cornea. Stem Cells 2009;27:2781-2792.
    • (2009) Stem Cells , vol.27 , pp. 2781-2792
    • Davies, S.B.1    Chui, J.2    Madigan, M.C.3
  • 64
    • 15244344965 scopus 로고    scopus 로고
    • Partial enrichment of a population of human limbal epithelial cells with putative stem cell properties based on collagen type IV adhesiveness
    • DOI 10.1016/j.exer.2004.11.011
    • Li D, Chen Z, Song XJ et al. Partial enrichment of a population of human limbal epithelial cells with putative stem cell properties based on collagen type IV adhesiveness. Exp Eye Res 2005;80:581-590. (Pubitemid 40387527)
    • (2005) Experimental Eye Research , vol.80 , Issue.4 , pp. 581-590
    • Li, D.-Q.1    Chen, Z.2    Song, X.J.3    De Paiva, C.S.4    Kim, H.-S.5    Pflugfelder, S.C.6
  • 65
    • 0027195638 scopus 로고
    • Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression
    • DOI 10.1016/0092-8674(93)90251-K
    • Jones PH, Watt FM. Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell 1993;73:713-724. (Pubitemid 23159010)
    • (1993) Cell , vol.73 , Issue.4 , pp. 713-724
    • Jones, P.H.1    Watt, F.M.2
  • 67
    • 3242753503 scopus 로고    scopus 로고
    • Molecular and mechanical synergy: Cross-talk between integrins and growth factor receptors
    • DOI 10.1016/j.cardiores.2004.04.027, PII S0008636304001993
    • Ross RS. Molecular and mechanical synergy: Cross-talk between integrins and growth factor receptors. Cardiovasc Res 2004;63:381-390. (Pubitemid 38970182)
    • (2004) Cardiovascular Research , vol.63 , Issue.3 , pp. 381-390
    • Ross, R.S.1
  • 68
    • 72749102066 scopus 로고    scopus 로고
    • The role of integrins in corneal wound healing
    • Carter RT. The role of integrins in corneal wound healing. Vet Opthalmol 2009;12:2-9.
    • (2009) Vet Opthalmol , vol.12 , pp. 2-9
    • Carter, R.T.1
  • 69
    • 3042653662 scopus 로고    scopus 로고
    • Regional distribution of α9β1 integrin within the limbus of the mouse ocular surface
    • DOI 10.1002/dvdy.20050
    • Pajoohesh-Ganji A, Pal-Ghosh S, Stepp MA. Regional distribution of α9β1 integrin within the limbus of the mouse ocular surface. Dev Dyn 2004;230:518-528. (Pubitemid 38802477)
    • (2004) Developmental Dynamics , vol.230 , Issue.3 , pp. 518-528
    • Pajoohesh-Ganji, A.1    Ghosh, S.P.2    Stepp, M.A.3
  • 71
    • 33745497922 scopus 로고    scopus 로고
    • Integrins in slow-cycling corneal epithelial cells at the limbus in the mouse
    • DOI 10.1634/stemcells.2005-0382
    • Pajoohesh-Ganji A, Pal-Ghosh S, Stepp MA. Integrins in slow-cycling corneal epithelial cells at the limbus in the mouse. Stem Cells 2006; 24:1075-1086. (Pubitemid 44464740)
    • (2006) Stem Cells , vol.24 , Issue.4 , pp. 1075-1086
    • Pajoohesh-Ganji, A.1    Pal-Ghosh, S.2    Simmens, S.J.3    Stepp, M.A.4
  • 72
    • 38349076151 scopus 로고    scopus 로고
    • Enrichment of corneal epithelial stem/progenitor cells using cell surface markers, integrin α6 and CD71
    • Hayashi R, Yamato M, Saito T et al. Enrichment of corneal epithelial stem/progenitor cells using cell surface markers, integrin α6 and CD71. Biochem Biophy Res Commun 2008;367:256-263.
    • (2008) Biochem Biophy Res Commun , vol.367 , pp. 256-263
    • Hayashi, R.1    Yamato, M.2    Saito, T.3
  • 74
    • 33846935723 scopus 로고    scopus 로고
    • Identification of candidate murine esophageal stem cells using a combination of cell kinetic studies and cell surface markers
    • DOI 10.1634/stemcells.2006-0421
    • Croagh D, Phillips WA, Redvers R et al. Identification of candidate murine esophageal stem cells using a combination of cell kinetics studies and cell surface markers. Stem Cells 2007;25:313-318. (Pubitemid 46232785)
    • (2007) Stem Cells , vol.25 , Issue.2 , pp. 313-318
    • Croagh, D.1    Phillips, W.A.2    Redvers, R.3    Thomas, R.J.S.4    Kaur, P.5
  • 77
    • 0037131389 scopus 로고    scopus 로고
    • 'Stemness': Transcriptional profiling of embryonic and adult stem cells
    • DOI 10.1126/science.1072530
    • Ramalho-Santos M, Yoon S et al. 'Stemness': Transcriptional profiling of embryonic and adult stem cells. Science 2002;298:597-600. (Pubitemid 35215313)
    • (2002) Science , vol.298 , Issue.5593 , pp. 597-600
    • Ramalho-Santos, M.1    Yoon, S.2    Matsuzaki, Y.3    Mulligan, R.C.4    Melton, D.A.5
  • 78
    • 0037130961 scopus 로고    scopus 로고
    • A stem cell molecular signature
    • Ivanova NB, Dimos JT, Schaniel C et al. A stem cell molecular signature. Science 2002;298:601-604.
    • (2002) Science , vol.298 , pp. 601-604
    • Ivanova, N.B.1    Dimos, J.T.2    Schaniel, C.3
  • 79
    • 0242367242 scopus 로고    scopus 로고
    • Comment on "'Stemness': Transcriptional profiling of embryonic and adult stem cells " and "A stem cell molecular signature "
    • Fortunel NO, Out HH, Ng H et al. Comment on "'Stemness': Transcriptional profiling of embryonic and adult stem cells " and "A stem cell molecular signature ". Science 2003;302:393.
    • (2003) Science , vol.302 , pp. 393
    • Fortunel, N.O.1    Out, H.H.2    Ng, H.3
  • 81
    • 0032514841 scopus 로고    scopus 로고
    • Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all αv integrins
    • Bader BL, Rayburn H, Crowley D et al. Extensive vasculogenesis, angiogenesis and organogenesis precede lethality in mice lacking all αv integrins. Cell 1998;95:507-519. (Pubitemid 28533307)
    • (1998) Cell , vol.95 , Issue.4 , pp. 507-519
    • Bader, B.L.1    Rayburn, H.2    Crowley, D.3    Hynes, R.O.4
  • 83
    • 44849100858 scopus 로고    scopus 로고
    • Genetic ablation of αv integrins in epithelial cells of the eyelid skin and conjunctiva leads to squamous cell carcinoma
    • DOI 10.2353/ajpath.2008.070700
    • McCarty JH, Barry M, Crowley D et al. Genetic ablation of αv integrins in epithelial cells of the eyelid skin and conjunctiva leads to squamous cell carcinoma. Am J Pathol 2008;172:1740-1747. (Pubitemid 351793364)
    • (2008) American Journal of Pathology , vol.172 , Issue.6 , pp. 1740-1747
    • McCarty, J.H.1    Barry, M.2    Crowley, D.3    Bronson, R.T.4    Lacy-Hulbert, A.5    Hynes, R.O.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.