Host cell cytokines induced by chlamydia pneumoniae decrease the expression of interstitial collagens and fibronectin in fibroblasts

Infection and Immunity

Volumn 77, Issue 2, 2009, Pages 867-876

  Baumert, Jürgen ^a   Schmidt, Karl Hermann ^a   Eitner, Annett ^a   Straube, Eberhard ^a   Rödel, Jürgen ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CCAAT ENHANCER BINDING PROTEIN BETA; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; CYCLOOXYGENASE 2; CYTOKINE; FIBRONECTIN; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 1ALPHA; INTERLEUKIN 8; INTERSTITIAL COLLAGENASE; MATRIX PROTEIN; PYRUVATE DEHYDROGENASE; SMALL INTERFERING RNA; COLLAGEN;

ARTICLE; ASTHMA; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CHLAMYDIASIS; CHLAMYDOPHILA PNEUMONIAE; CHRONIC OBSTRUCTIVE LUNG DISEASE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; FIBROBLAST; GENETIC TRANSFECTION; HOST CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOBLOTTING; INTIMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; CELL LINE; CULTURE MEDIUM; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MICROBIOLOGY; PHYSIOLOGY;

CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE; CHLAMYDOPHILA PNEUMONIAE; COLLAGEN; CULTURE MEDIA, CONDITIONED; CYTOKINES; FIBROBLASTS; FIBRONECTINS; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS;

EID: 60549087893     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00566-08     Document Type: Article

References (54)

1. Alonso, C. R., J. George, C. G. Pesce, D. M. Bissell, and A. R. Kornblihtt. 2002. Fibronectin transcription in liver cells: promoter occupation and function in sinusoidal endothelial cells and hepatocytes. Biochem. Biophys. Res. Commun. 295:1077-1084.
2. Beaty, C. D., J. T. Grayston, S. P. Wang, C.-C. Kuo, C. S. Reto, and T. R. Martin. 1991. Chlamydia pneumoniae, strain TWAR, infection in patients with chronic obstructive pulmonary disease. Am. Rev. Respir. Dis. 144:1408- 1410.
3. Bergeron, C., and L.-P. Boulet. 2006. Structural changes in airway diseases: characteristics, mechanisms, consequences, and pharmacologic modulation. Chest 129:1068-1087.
4. Biscione, G. L., J. Corne, A. J. Chauhan, and S. L. Johnston. 2004. Increased frequencv of detection of Chlamydophila pneumoniae in asthma. Eur. Respir. J. 24:745-749.
5. Blasi, F., S. Aliberti, L. Allegra, G. Piatti, P. Tarsia, J. M. Ossewarde, V. Verweij, F. P. Nijkamp, and G. Folkerts. 2007. Chlamydophila pneumoniae induces a sustained airway hyperresponsiveness and inflammation in mice. Respir. Res. 8:83.
6. Brandén, E., J. Gnarpe, G. Hillerdal, L. Orre, C. M. Sköld, M. Löfdahl, H. Koyi, and G. Tornling. 2007. Detection of Chlamydia pneumoniae on cytospin preparations from bronchoalveolar lavage in COPD patients and in lung tissue from advanced emphysema. Int. J. Chron. Obstruct. Pulmon. Dis. 2:643-650.
7. Buchholz, K. R., and R. S. Stephens. 2006. Activation of the host cell proinflammatory interleukin-8 response by Chlamydia trachomatis. Cell. Microbiol. 8:1768-1779.
8. de Kruif, M. D., E. C. M. van Gorp, T. T. Keller, J. M. Ossewarde, and H. ten Kate. 2005. Chlamydia pneumoniae infections in mouse models: relevance for atherosclerosis research. Cardiovasc. Res. 65:317-327.
9. Diaz, A., E. Munoz, R. Johnston, J. H. Korn, and S. A. Jimenez. 1993. Regulation of human fibroblast alpha 1(1) procollagen gene expression by tumor necrosis factor-α, interleukin-lβ and prostaglandin W2. J. Biol. Chem. 268:10364-10371.
10. Elias, J. A., Z. Zhu, G. Chupp, and R. J. Homer. 1999. Airway remodeling in asthma. J. Clin. Investig. 104:1001-1006.
11. Ghosh, A. K. 2002. Factors involved in the regulation of type I collagen gene expression: implication in fibrosis. Exp. Biol. Med. 227:301-314.
12. Ghosh, A. K., S. Bhattacharyya, Y. Mori, and J. Varga. 2006. Inhibition of collagen gene expression by interferon-γ:novel role of the CCAAT/enhancer- binding protein β (C/EBPβ). J. Cell. Physiol. 207:251-260.
13. Greenwel, P., S. Tanaka, D. Penkov, W. Zhang, M. Olive, J. Moll, C. Vinson, M. di Liberto, and F. Ramirez. 2000. Tumor necrosis factor alpha inhibits type I collagen synthesis through repressive CCAAT/enhancer-binding protein. Mol. Cell. Biol. 20:912-918.
14. Hahn, D. L., R. W. Dodge, and R. Golubjatnikov. 1991. Association of Chlamydia pneumoniae (strain TWAR) infection with wheezing, asthmatic bronchitis, and adult-onset asthma. JAMA 266:225-230.
15. Han, S., J. D. Ritzenthaler, H. N. Rivera, and J. Roman. 2005. Peroxisome proliferator-activated receptor-gamma ligands suppress fibronectin gene expression in human lung carcinoma cells: involvement of both CRE and Spl. Am. J. Physiol. Lung Cell. Mol. Physiol. 289:L419-L428.
16. Heinemann, M., M. Susa, U. Simnacher, R. Marre, and A. Essig. 1996. Growth of Chlamydia pneumoniae induces cytokine production and expression of CD14 in a human monocytic cell line. Infect, Immun. 64:4872-4875.
17. Homma, J., R. Yamanaka, N. Yajima, N. Tsuchiya, N. Genkai, M. Sano, and R. Tanaka. 2006. Increased expression of CCAAT/enhancer binding protein beta correlates with prognosis in glioma patients. Oncol. Rep. 15:595-601.
18. Ieven, M. M., and V. Y. Hoymans. 2005. Involvement of Chlamydia pneumoniae in atherosclerosis: more evidence for lack of evidence. J. Clin. Microbiol. 43:19-24.
19. Johnston, S. L., and R. J. Martin. 2005. Chlamydophila pneumoniae and Mycoplasma pneumoniae: a role in asthma pathogenesis? Am. J. Respir. Crit. Care Med. 172:1078-1089.
20. Kennedy, S. H., H. Qin, L. Lin, and E. M. Tan. 1995. Basic fibroblast growth factor regulates type I collagen and collagenase production in human smooth muscle cells. Am. J. Pathol. 146:764-771.
21. Reference deleted.
22. Krieg, R., A. Eitner, W. Günther, and K.-J. Halbhuber. 2007. Optimization of heterocyclic 4-hydroxystyryl derivatives for histological localization of endogenous and immunobound peroxidase activity. Biotech. Histochem. 82:235-262.
23. Li, X. L., M. Boyanapalli, X. Weihua, D. V. Kalvakolanu, and B. Hassel. 1998. Induction of interferon synthesis and activation of interferon-stimulated genes by liposomal transfection reagents. J. Interferon Cytokine Res. 18:947-952.
24. Libby, P. 1995. Molecular bases of the acute coronary syndrome. Circulation 91:2844-2850.
25. Miyashita, N., H. Fukano, H. Hara, K. Yoshida, Y. Niki, and T. Matsushima. 2002. Recurrent pneumonia due to persistent Chlamydia pneumoniae infection. Intern. Med. 41:30-33.
26. Nagineni, C. N., K. Pardhasaradhi, M. C. Martins, B. Detrick, and J. J. Hooks. 1996. Mechanisms of interferon-induced inhibition of Toxoplasma gondii replication in human retinal pigment epithelial cells. Infect, lmmun. 64:4188-4196.
27. Nusgens, B. V., P. Humbert, A. Rougier, A. C. Colige, M. Haftek, C. A. Lambert, A. Richard, P. Creidi, and C. M. Lapière. 2001. Topically applied vitamin C enhances the mRNA level of collagens I and III. their processing enzymes and tissue inhibitor of matrix metalloproteinase 1 in the human dermis. J. lnvestig. Dermatol. 116:853-859.
28. Penttilä, T-, A. Haveri, A. Tammiruusu, J. M. Vuola, R. Lahesmaa, and M. Puolakkainen. 2008. Chlamydia pneumoniae infection in IL-10 knock-out mice: accelerated clearance but severe pulmonary inflammatory response. Microb. Pathogen. 45:25-29.
29. Ramirez, F., S. Tanaka, and G. Bou-Gharios. 2006. Transcriptional regulation of the human α2(1) collagen gene (COL1A2), an informative model system to study fibrotic diseases. Matrix Biol. 25:365-372.
30. Reinhold, P., N. Kirschvink, D. Theegarten, and A. Berndt. 2008. An experimentally induced Chlamydia suis infection in pigs results in severe lung function disorders and pulmonary inflammation. Vet. Res. 39:35.
31. Rinaldi, N., M. Willhauck, D. Weis, B. Brado, P. Kern, M. Lukoschek, M. Schwarz-Eywill, and T. F. E. Barth. 2001. Loss of collagen type IV in rheumatoid synovia and cytokine effect on the collagen type-lV gene expression in fibroblast-like synoviocytes from rheumatoid arthritis. Virchows Arch. 439:675-682.
32. Riquet, F. B., W. F. Lai, J. R. Birkhead, L. F. Suen, G. Karsenty, and M. B. Goldring. 2000. Suppression of type 1 collagen gene expression by prostaglandins in fibroblasts is mediated at the transcriptional level. Mol. Med. 6:705-719.
33. Roan, N. R., and M. N. Starnbach. 2008. Immune-mediated control of Chlamydia infection. Cell. Microbiol. 10:9-19.
34. Rödel, J., A. Groh, H. Vogelsang, M. Lehmann, M. Hartmann, and E. Straube. 1998. Beta interferon is produced by Chlamydia trachomatis-in-fected fibroblast-like synoviocytes and inhibits gamma interferon-induced HLA-DR expression. Infect, lmmun. 66:4491-4495.
35. Rödel, J., D. Prochnau, K. Prager, E. Pentcheva, M. Hartmann, and E. Straube. 2003. Increased production of matrix metalloproteinases 1 and 3 by smooth muscle cells upon infection with Chlamydia pneumoniae. FEMS Immunol. Med. Microbiol. 38:159-164.
36. Rödel, J., M, Woytas, A. Groh, K.-H. Schmidt, M. Hartmann, M. Lehmann, and E. Straube. 2000. Production of basic fibroblast growth factor and interleukin 6 by human smooth muscle cells following infection with Chlamydia pneumoniae. Infect. lmmun. 68:3635-3641.
37. Rolfs, A., I. Schuller, U. Finckh, and L Weber-Rolfs. 1992. PCR: clinical diagnostics and research. Springer-Verlag, Berlin, Germany.
38. Ross, R. 1999. Atherosclerosis-an inflammatory disease. N. Engl. J. Med. 340:115-126.
39. Rothfuchs, A. G., C. Trumstedt, F. Mattel, G. Schiavoni, Å. Hidmark, H. Wigzell, and M. E. Rottenberg. 2006. STAT1 regulates IFN-αβ- and 1FN- γ-dependent control of infection with Chlamydia pneumoniae by nonhemopoietic cells. J. Immunol. 176:6982-6990.
40. Rupp, J., D. Droemann, T. Goldmann, P. Zabel, W. Solbach, E. Vollmer, D. Branscheid, K. Dalhoff, and M. Maass. 2004. Alveolar epithelial cells type II are major target cells for C. pneumoniae in chronic but not in acute respiratory infection. FEMS Immunol. Med. Microbiol. 41:197-203.
41. Saikku, P., M. Leinonen, K. Mattila, M, R. Ekman, M. S. Nieminen, P. H. Makela, J. K. Huttonen, and V. Valtonen. 1988. Serological evidence of anassociation of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction. Lancet 2:983-986.
42. Schmidt, R., V. Redecke, Y. Breitfeld, N. Wanita, T. Miethke, S. Massberg, S. Fischel, F.-J. Neumann, A. Schömig, and A. E. May. 2006. EMMPR1N (CD 147) is a central activator of extracellular matrix degradation by Chlamydia pneumoniae-infected monocytes. Implications for plaque rupture. Thromb. Haemost. 95:151-158.
43. Schmidt, S. M., C. E. Müller, and S. K. W. Wiersbitzky. 2005. Inverse association between Chlamydia pneumoniae respiratory tract infection and initiation of asthma or allergic rhinitis in children. Pediatr. Allergy Immunol. 16:137-144.
44. Shor, A., J. I. Phillips, G. Ong, B. J. Thomas, and D. Taylor-Robinson. 1998. Chlamydia pneumoniae in atheroma: consideration of criteria for causality. J. Clin. Pathol. 51:812-817.
45. Subbarayan, V., A. L. Sabichi, N. Llansa, S. M. Lippman, and D. G. Menter. 2001. Differential expression of cyclooxygenase-2 and its regulation by tumor necrosis factor-a in normal and malignant prostate cells. Cancer Res. 61: 2720-2726.
46. Tanabe, J., A. Izawa, N. Takemi, Y. Miyauchi, Y. Torii, H. Tsuchiyama, T. Suzuki, S. Sone, and K. Ando. 2007. lnterferon-beta reduces the mouse liver fibrosis induced by repeated administration of concanavalin A via the direct and indirect effects. Immunology 122:562-570.
47. Theegarten, D., G. Mogilevski, O. Anhenn, G. Stamatis, R. Jaeschock, and K. Morgenroth. 2000. The role of Chlamydia in the pathogenesis of pulmonary emphysema: electron microscopy and immunofluorescence reveal corresponding findings as in atherosclerosis. Virchows Arch. 437:190-193.
48. Vignola, A. M., F. Mirabella, G. Costanzo, R. Di Giorni, M. Cjomarkaj, V. Bellia, and G. Monsignore. 2003. Airway remodeling in asthma. Chest 123: 417S-422S.
49. Vignola, A. M., P. Chanez, G. Chiappara, A. Merendino, E. Pace, A. Rizzo, A. M. la Rocca, V. Bellia, G. Bonsignore, and J. Bousquet. 1997. Transforming growth factor-beta expression in mucosal biopsies in asthma and chronic bronchitis. Am. J. Respir. Crit. Care Med. 156:591-599.
50. Von Hertzen, L., H. Alakärppä, R. Koskinen, K. Liippo, H. M. Surcel, M. Leinonen, and P. Saikku. 1997. Chlamydia pneumoniae infection in patients with chronic obstructive airway disease. Epidemiol. Infect. 118: 155-164.
51. von Lampe, B., B. Barthel, S. E. Coupland, E.-O. Riecken, and S. Rockewicz. 2000. Differential expression of matrix metalloproteinases and their tissue inhibitors in colon mucosa of patients with inflammatory bowel disease. Gut 47:63-73.
52. Webley, W. C., P. S. Salva, C. Andrzejewski, F. Cirino, C. A. West, Y. Tilahun, and E. S. Stuart. 2005. The bronchial lavage of pediatric patients with asthma contains infectious Chlamydia. Am. J. Respir. Crit. Care Med. 171:1083-1088.
53. Williams, D. M., B. G. Grubbs, S. Park-Snyder, R. G. Rank, and L. F. Bonewald. 1996. Activation of latent transforming growth factor beta during Chlamydia trachomatis-induced murine pneumonia. Res. Microbiol. 147: 251-262.
54. Xue, M. L., H. Zhu, A. Thakur, and M. Willcox. 2002. 1-alpha.25-Dihy- droxyvitamin D3 inhibits proinflammatory cytokine and chemokine expression in human corneal epithelial cells colonized with Pseudomonas aeruginosa. Immunol. Cell Biol. 80:340-345.