메뉴 건너뛰기




Volumn 2, Issue 12, 2011, Pages

HLA-B-associated transcript 3 (Bat3/Scythe) negatively regulates Smad phosphorylation in BMP signaling

Author keywords

Bat3 Scythe BAG6; BMP; Phosphatase; Phosphorylation; Smad; TGF

Indexed keywords

ALKALINE PHOSPHATASE; BAT3 PROTEIN; BONE MORPHOGENETIC PROTEIN; PROTEIN; SMAD PROTEIN; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; BAG6 PROTEIN, MOUSE; CARRIER PROTEIN; CHAPERONE; IDB1 PROTEIN, MOUSE; INHIBITOR OF DIFFERENTIATION 1; NUCLEAR PROTEIN; SMALL INTERFERING RNA; STEROL CARRIER PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84856078546     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2011.114     Document Type: Article
Times cited : (7)

References (41)
  • 1
    • 23044466047 scopus 로고    scopus 로고
    • Specificity and versatility in TGF-β signaling through smads
    • DOI 10.1146/annurev.cellbio.21.022404.142018
    • Feng XH, Derynck R. Specificity and versatility in tgf-beta signaling through Smads. Annu Rev Cell Dev Biol 2005; 21: 659-693. (Pubitemid 41740650)
    • (2005) Annual Review of Cell and Developmental Biology , vol.21 , pp. 659-693
    • Feng, X.-H.1    Derynck, R.2
  • 2
    • 70450187617 scopus 로고    scopus 로고
    • The regulation of tgfbeta signal transduction
    • Moustakas A, Heldin CH. The regulation of TGFbeta signal transduction. Development 2009; 136: 3699-3714.
    • (2009) Development , vol.136 , pp. 3699-3714
    • Moustakas, A.1    Heldin, C.H.2
  • 3
    • 58149239733 scopus 로고    scopus 로고
    • Roles of tgf-beta family signaling in stem cell renewal and differentiation
    • Watabe T, Miyazono K. Roles of TGF-beta family signaling in stem cell renewal and differentiation. Cell Res 2009; 19: 103-115.
    • (2009) Cell Res , vol.19 , pp. 103-115
    • Watabe, T.1    Miyazono, K.2
  • 5
    • 33846002754 scopus 로고    scopus 로고
    • Protein serine/threonine phosphatase PPM1A dephosphorylates Smad1 in the bone morphogenetic protein signaling pathway
    • DOI 10.1074/jbc.M605169200
    • Duan X, Liang YY, Feng XH, Lin X. Protein serine/threonine phosphatase PPM1A dephosphorylates Smad1 in the bone morphogenetic protein signaling pathway. J Biol Chem 2006; 281: 36526-36532. (Pubitemid 46042119)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.48 , pp. 36526-36532
    • Duan, X.1    Liang, Y.-Y.2    Feng, X.-H.3    Lin, X.4
  • 6
    • 33644996932 scopus 로고    scopus 로고
    • Identification of phosphatases for smad in the bmp/dpp pathway
    • Chen HB, Shen J, Ip YT, Xu L. Identification of phosphatases for Smad in the BMP/DPP pathway. Genes Dev 2006; 20: 648-653.
    • (2006) Genes Dev , vol.20 , pp. 648-653
    • Chen, H.B.1    Shen, J.2    Ip, Y.T.3    Xu, L.4
  • 8
    • 33846028557 scopus 로고    scopus 로고
    • Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-β signaling
    • DOI 10.1074/jbc.M607246200
    • Wrighton KH, Willis D, Long J, Liu F, Lin X, Feng XH. Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-beta signaling. J Biol Chem 2006; 281: 38365-38375. (Pubitemid 46041960)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.50 , pp. 38365-38375
    • Wrighton, K.H.1    Willis, D.2    Long, J.3    Liu, F.4    Lin, X.5    Feng, X.-H.6
  • 9
    • 0032476659 scopus 로고    scopus 로고
    • Scythe: A novel reaper-binding apoptotic regulator
    • DOI 10.1093/emboj/17.21.6135
    • Thress K, Henzel W, Shillinglaw W, Kornbluth S. Scythe: a novel reaper-binding apoptotic regulator. EMBO J 1998; 17: 6135-6143. (Pubitemid 28497787)
    • (1998) EMBO Journal , vol.17 , Issue.21 , pp. 6135-6143
    • Thress, K.1    Henzel, W.2    Shillinglaw, W.3    Kornbluth, S.4
  • 10
    • 0025261931 scopus 로고
    • A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and A single ubiquitin-like domain
    • Banerji J, Sands J, Strominger JL, Spies T. A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain. Proc Natl Acad Sci USA 1990; 87: 2374-2378.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2374-2378
    • Banerji, J.1    Sands, J.2    Strominger, J.L.3    Spies, T.4
  • 12
    • 55449121084 scopus 로고    scopus 로고
    • Bat3 and set1a form a complex with ctcfl/boris to modulate h3k4 histone dimethylation and gene expression
    • Nguyen P, Bar-Sela G, Sun L, Bisht KS, Cui H, Kohn E et al. BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression. Mol Cell Biol 2008; 28: 6720-6729.
    • (2008) Mol Cell Biol , vol.28 , pp. 6720-6729
    • Nguyen, P.1    Bar-Sela, G.2    Sun, L.3    Bisht, K.S.4    Cui, H.5    Kohn, E.6
  • 14
    • 0033570176 scopus 로고    scopus 로고
    • Reaper-induced dissociation of a Scythe-sequestered cytochrome c-releasing activity
    • DOI 10.1093/emboj/18.20.5486
    • Thress K, Evans EK, Kornbluth S. Reaper-induced dissociation of a Scythe-sequestered cytochrome c-releasing activity. EMBO J 1999; 18: 5486-5493. (Pubitemid 29486368)
    • (1999) EMBO Journal , vol.18 , Issue.20 , pp. 5486-5493
    • Thress, K.1    Evans, E.K.2    Kornbluth, S.3
  • 15
    • 27944446355 scopus 로고    scopus 로고
    • The reaper-binding protein Scythe modulates apoptosis and proliferation during mammalian development
    • DOI 10.1128/MCB.25.23.10329-10337.2005
    • Desmots F, Russell HR, Lee Y, Boyd K, McKinnon PJ. The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development. Mol Cell Biol 2005; 25: 10329-10337. (Pubitemid 41681958)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.23 , pp. 10329-10337
    • Desmots, F.1    Russell, H.R.2    Lee, Y.3    Boyd, K.4    McKinnon, P.J.5
  • 16
    • 0022380768 scopus 로고
    • The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
    • DOI 10.1038/318533a0
    • Adams JM, Harris AW, Pinkert CA, Corcoran LM, Alexander WS, Cory S et al. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature 1985; 318: 533-538. (Pubitemid 16173038)
    • (1985) Nature , vol.318 , Issue.6046 , pp. 533-538
    • Adams, J.M.1    Harris, A.W.2    Pinkert, C.A.3
  • 17
    • 34147156192 scopus 로고    scopus 로고
    • HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53
    • DOI 10.1101/gad.1534107
    • Sasaki T, Gan EC, Wakeham A, Kornbluth S, Mak TW, Okada H. HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53. Genes Dev 2007; 21: 848-861. (Pubitemid 46572363)
    • (2007) Genes and Development , vol.21 , Issue.7 , pp. 848-861
    • Sasaki, T.1    Gan, E.C.2    Wakeham, A.3    Kornbluth, S.4    Mak, T.W.5    Okada, H.6
  • 18
    • 77956183398 scopus 로고    scopus 로고
    • A ribosome-associating factor chaperones tail-anchored membrane proteins
    • Mariappan M, Li X, Stefanovic S, Sharma A, Mateja A, Keenan RJ et al. A ribosome-associating factor chaperones tail-anchored membrane proteins. Nature 2010; 466: 1120-1124.
    • (2010) Nature , vol.466 , pp. 1120-1124
    • Mariappan, M.1    Li, X.2    Stefanovic, S.3    Sharma, A.4    Mateja, A.5    Keenan, R.J.6
  • 19
    • 77954352789 scopus 로고    scopus 로고
    • Bat3 promotes the membrane integration of tail-anchored proteins
    • Leznicki P, Clancy A, Schwappach B, High S. Bat3 promotes the membrane integration of tail-anchored proteins. J Cell Sci 2010; 123: 2170-2178.
    • (2010) J Cell Sci , vol.123 , pp. 2170-2178
    • Leznicki, P.1    Clancy, A.2    Schwappach, B.3    High, S.4
  • 20
    • 79960637590 scopus 로고    scopus 로고
    • Protein targeting and degradation are coupled for elimination of mislocalized proteins
    • Hessa T, Sharma A, Mariappan M, Eshleman HD, Gutierrez E, Hegde RS. Protein targeting and degradation are coupled for elimination of mislocalized proteins. Nature 2011; 475: 394-397.
    • (2011) Nature , vol.475 , pp. 394-397
    • Hessa, T.1    Sharma, A.2    Mariappan, M.3    Eshleman, H.D.4    Gutierrez, E.5    Hegde, R.S.6
  • 21
    • 77955878748 scopus 로고    scopus 로고
    • Bag-6 is essential for selective elimination of defective proteasomal substrates
    • Minami R, Hayakawa A, Kagawa H, Yanagi Y, Yokosawa H, Kawahara H. BAG-6 is essential for selective elimination of defective proteasomal substrates. J Cell Biol 2010; 190: 637-650.
    • (2010) J Cell Biol , vol.190 , pp. 637-650
    • Minami, R.1    Hayakawa, A.2    Kagawa, H.3    Yanagi, Y.4    Yokosawa, H.5    Kawahara, H.6
  • 22
    • 50349094328 scopus 로고    scopus 로고
    • Bat3 interacts with transforming growth factor-beta (TGF-beta) receptors and enhances tgf-beta1-induced type i collagen expression in mesangial cells
    • Kwak JH, Kim SI, Kim JK, Choi ME. BAT3 interacts with transforming growth factor-beta (TGF-beta) receptors and enhances TGF-beta1-induced type I collagen expression in mesangial cells. J Biol Chem 2008; 283: 19816-19825.
    • (2008) J Biol Chem , vol.283 , pp. 19816-19825
    • Kwak, J.H.1    Kim, S.I.2    Kim, J.K.3    Choi, M.E.4
  • 24
    • 34547122921 scopus 로고    scopus 로고
    • Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors
    • DOI 10.1074/jbc.M702100200
    • Goto K, Kamiya Y, Imamura T, Miyazono K, Miyazawa K. Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors. J Biol Chem 2007; 282: 20603-20611. (Pubitemid 47100044)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.28 , pp. 20603-20611
    • Goto, K.1    Kamiya, Y.2    Imamura, T.3    Miyazono, K.4    Miyazawa, K.5
  • 25
    • 58149239730 scopus 로고    scopus 로고
    • Phospho-control of tgf-beta superfamily signaling
    • Wrighton KH, Lin X, Feng X-H. Phospho-control of TGF-beta superfamily signaling. Cell Res 2009; 19: 8-20.
    • (2009) Cell Res , vol.19 , pp. 8-20
    • Wrighton, K.H.1    Lin, X.2    Feng, X.-H.3
  • 26
    • 33845970267 scopus 로고    scopus 로고
    • Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-β pathways
    • DOI 10.1074/jbc.M610172200
    • Sapkota G, Knockaert M, Alarcón C, Montalvo E, Brivanlou AH, Massagué J. Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways. J Biol Chem 2006; 281: 40412-40419. (Pubitemid 46041844)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.52 , pp. 40412-40419
    • Sapkota, G.1    Knockaert, M.2    Alarco, C.3    Montalvo, E.4    Brivanlou, A.H.5    Massague, J.6
  • 27
    • 0038548187 scopus 로고    scopus 로고
    • Attenuation of the TGF-β-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-β-induced growth arrest
    • DOI 10.1038/sj.onc.1206420
    • Nicolas FJ, Hill CS. Attenuation of the TGF-beta-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-beta-induced growth arrest. Oncogene 2003; 22: 3698-3711. (Pubitemid 36760732)
    • (2003) Oncogene , vol.22 , Issue.24 , pp. 3698-3711
    • Nicolas, F.J.1    Hill, C.S.2
  • 28
    • 77956682613 scopus 로고    scopus 로고
    • Regulation of tgf-beta signalling by protein phosphatases
    • Liu T, Feng XH. Regulation of TGF-beta signalling by protein phosphatases. Biochem J 2010; 430: 191-198.
    • (2010) Biochem J , vol.430 , pp. 191-198
    • Liu, T.1    Feng, X.H.2
  • 29
    • 57049158952 scopus 로고    scopus 로고
    • Cold Spring Harbor Laboratory Press: Cold Spring Harbor, New York, USA
    • Derynck R, Miyazono Ko. The TGF-beta Family. Cold Spring Harbor Laboratory Press: Cold Spring Harbor, New York, USA, 2008.
    • (2008) The TGF-beta Family
    • Derynck, R.1    Miyazono, K.O.2
  • 30
    • 0035282773 scopus 로고    scopus 로고
    • Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper
    • DOI 10.1093/emboj/20.5.1033
    • Thress K, Song J, Morimoto RI, Kornbluth S. Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper. EMBO J 2001; 20: 1033-1041. (Pubitemid 32186794)
    • (2001) EMBO Journal , vol.20 , Issue.5 , pp. 1033-1041
    • Thress, K.1    Song, J.2    Morimoto, R.I.3    Kornbluth, S.4
  • 31
    • 63649113699 scopus 로고    scopus 로고
    • Origin and function of ubiquitin-like proteins
    • Hochstrasser M. Origin and function of ubiquitin-like proteins. Nature 2009; 458: 422-429.
    • (2009) Nature , vol.458 , pp. 422-429
    • Hochstrasser, M.1
  • 32
    • 77952896646 scopus 로고    scopus 로고
    • Tgfbeta signalling: A complex web in cancer progression
    • Ikushima H, Miyazono K. TGFbeta signalling: a complex web in cancer progression. Nat Rev Cancer 2010; 10: 415-424.
    • (2010) Nat Rev Cancer , vol.10 , pp. 415-424
    • Ikushima, H.1    Miyazono, K.2
  • 33
    • 33747065208 scopus 로고    scopus 로고
    • Morphogenesis of the trachea and esophagus: Current players and new roles for noggin and Bmps
    • DOI 10.1111/j.1432-0436.2006.00096.x
    • Que J, Choi M, Ziel JW, Klingensmith J, Hogan BL. Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps. Differentiation 2006; 74: 422-437. (Pubitemid 44215412)
    • (2006) Differentiation , vol.74 , Issue.7 , pp. 422-437
    • Que, J.1    Choi, M.2    Ziel, J.W.3    Klingensmith, J.4    Hogan, B.L.M.5
  • 35
    • 78649982907 scopus 로고    scopus 로고
    • The dynamic roles of tgf-beta in cancer
    • Meulmeester E, Ten Dijke P. The dynamic roles of TGF-beta in cancer. J Pathol 2011; 223: 205-218.
    • (2011) J Pathol , vol.223 , pp. 205-218
    • Meulmeester, E.1    Ten Dijke, P.2
  • 36
    • 47549090432 scopus 로고    scopus 로고
    • Tgfbeta in cancer
    • Massague J. TGFbeta in cancer. Cell 2008; 134: 215-230.
    • (2008) Cell , vol.134 , pp. 215-230
    • Massague, J.1
  • 39
    • 33646033137 scopus 로고    scopus 로고
    • A lentiviral rnai library for human and mouse genes applied to an arrayed viral high-content screen
    • Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G et al. A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell 2006; 124: 1283-1298.
    • (2006) Cell , vol.124 , pp. 1283-1298
    • Moffat, J.1    Grueneberg, D.A.2    Yang, X.3    Kim, S.Y.4    Kloepfer, A.M.5    Hinkle, G.6
  • 40
    • 1442313955 scopus 로고    scopus 로고
    • Endogenous TGF-β signaling suppresses maturation of osteoblastic mesenchymal cells
    • DOI 10.1038/sj.emboj.7600067
    • Maeda S, Hayashi M, Komiya S, Imamura T, Miyazono K. Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells. EMBO J 2004; 23: 552-563. (Pubitemid 38282387)
    • (2004) EMBO Journal , vol.23 , Issue.3 , pp. 552-563
    • Maeda, S.1    Hayashi, M.2    Komiya, S.3    Imamura, T.4    Miyazono, K.5
  • 41
    • 1542270155 scopus 로고    scopus 로고
    • Regulation of transforming growth factor-β and bone morphogenetic protein signalling by transcriptional coactivator GCN5
    • DOI 10.1111/j.1365-2443.2004.00706.x
    • Kahata K, Hayashi M, Asaka M, Hellman U, Kitagawa H, Yanagisawa J et al. Regulation of transforming growth factor-beta and bone morphogenetic protein signalling by transcriptional coactivator GCN5. Genes Cells 2004; 9: 143-151. (Pubitemid 38312958)
    • (2004) Genes to Cells , vol.9 , Issue.2 , pp. 143-151
    • Kahata, K.1    Hayashi, M.2    Asaka, M.3    Hellman, U.4    Kitagawa, H.5    Yanagisawa, J.6    Kato, S.7    Imamura, T.8    Miyazono, K.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.