메뉴 건너뛰기




Volumn 14, Issue 9, 2011, Pages 1247-1256

From understanding synaptic plasticity to the development of cognitive enhancers

Author keywords

Alzheimer's disease; BDNF; dendritic spines; depression; synaptic plasticity

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE INHIBITOR; GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NOOTROPIC AGENT;

EID: 84856069899     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145710001537     Document Type: Review
Times cited : (14)

References (73)
  • 1
    • 34248342249 scopus 로고    scopus 로고
    • TRPC3 channels are necessary for brain-derived neurotrophic factor to activate a nonselective cationic current and to induce dendritic spine formation
    • DOI 10.1523/JNEUROSCI.5499-06.2007
    • Amaral MD, Pozzo-Miller L (2007). TRPC3 channels are necessary for brain-derived neurotrophic factor to activate a nonselective cationic current and to induce dendritic spine formation. Journal of Neuroscience 27, 5179-5189. (Pubitemid 46741779)
    • (2007) Journal of Neuroscience , vol.27 , Issue.19 , pp. 5179-5189
    • Amaral, M.D.1    Pozzo-Miller, L.2
  • 2
    • 77953807421 scopus 로고    scopus 로고
    • Chronic fluoxetine treatment induces structural plasticity and selective changes in glutamate receptor subunits in the rat cerebral cortex
    • Ampuero E, Rubio FJ, Falcon R, Sandoval M, et al. (2010). Chronic fluoxetine treatment induces structural plasticity and selective changes in glutamate receptor subunits in the rat cerebral cortex. Neuroscience 169, 98-108.
    • (2010) Neuroscience , vol.169 , pp. 98-108
    • Ampuero, E.1    Rubio, F.J.2    Falcon, R.3    Sandoval, M.4
  • 5
    • 77952400307 scopus 로고    scopus 로고
    • Interactive effects of stress and aging on structural plasticity in the prefrontal cortex
    • Bloss EB, Janssen WG, McEwen BS, Morrison JH (2010). Interactive effects of stress and aging on structural plasticity in the prefrontal cortex. Journal of Neuroscience 30, 6726-6731.
    • (2010) Journal of Neuroscience , vol.30 , pp. 6726-6731
    • Bloss, E.B.1    Janssen, W.G.2    McEwen, B.S.3    Morrison, J.H.4
  • 6
    • 56549084442 scopus 로고    scopus 로고
    • Local protein synthesis actin dynamics, and LTP consolidation
    • Bramham CR (2008). Local protein synthesis, actin dynamics, and LTP consolidation. Current Opinion in Neurobiology 18, 524-531.
    • (2008) Current Opinion in Neurobiology , vol.18 , pp. 524-531
    • Bramham, C.R.1
  • 8
    • 0035338399 scopus 로고    scopus 로고
    • Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect
    • DOI 10.1016/S0006-3223(00)01114-8, PII S0006322300011148
    • Chen AC, Shirayama Y, Shin KH, Neve RL, et al. (2001). Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect. Biological Psychiatry 49, 753-762. (Pubitemid 32452296)
    • (2001) Biological Psychiatry , vol.49 , Issue.9 , pp. 753-762
    • Chen, A.C.-H.1    Shirayama, Y.2    Shin, K.-H.3    Neve, R.L.4    Duman, R.S.5
  • 9
    • 47749114182 scopus 로고    scopus 로고
    • Changes in rat hippocampal CA1 synapses following imipramine treatment
    • DOI 10.1002/hipo.20423
    • Chen F, Madsen TM, Wegener G, Nyengaard JR (2008a). Changes in rat hippocampal CA1 synapses following imipramine treatment. Hippocampus 18, 631-639. (Pubitemid 352032389)
    • (2008) Hippocampus , vol.18 , Issue.7 , pp. 631-639
    • Chen, F.1    Madsen, T.M.2    Wegener, G.3    Nyengaard, J.R.4
  • 10
    • 40849141136 scopus 로고    scopus 로고
    • Rapid loss of dendritic spines after stress involves derangement of spine dynamics by corticotropin-releasing hormone
    • DOI 10.1523/JNEUROSCI.0225-08.2008
    • Chen Y, Dube CM, Rice CJ, Baram TZ (2008b). Rapid loss of dendritic spines after stress involves derangement of spine dynamics by corticotropin-releasing hormone. Journal of Neuroscience 28, 2903-2911. (Pubitemid 351398866)
    • (2008) Journal of Neuroscience , vol.28 , Issue.11 , pp. 2903-2911
    • Chen, Y.1    Dube, C.M.2    Rice, C.J.3    Baram, T.Z.4
  • 11
    • 77955604556 scopus 로고    scopus 로고
    • Correlated memory defects and hippocampal dendritic spine loss after acute stress involve corticotropin-releasing hormone signaling
    • Chen Y, Rex CS, Rice CJ, Dube CM, et al. (2010). Correlated memory defects and hippocampal dendritic spine loss after acute stress involve corticotropin-releasing hormone signaling. Proceedings of the National Academy of Sciences USA 107, 13123-13128.
    • (2010) Proceedings of the National Academy of Sciences USA , vol.107 , pp. 13123-13128
    • Chen, Y.1    Rex, C.S.2    Rice, C.J.3    Dube, C.M.4
  • 12
    • 33645962807 scopus 로고    scopus 로고
    • Synaptic roles of Cdk5: Implications in higher cognitive functions and neurodegenerative diseases
    • Cheung ZH, Fu AK, Ip NY (2006). Synaptic roles of Cdk5: implications in higher cognitive functions and neurodegenerative diseases. Neuron 50, 13-18.
    • (2006) Neuron , vol.50 , pp. 13-18
    • Zh, C.1    Fu, A.K.2    Ip, N.Y.3
  • 13
    • 77951498581 scopus 로고    scopus 로고
    • New neurons and new memories: How does adult hippocampal neurogenesis affect learning and memory?
    • Deng W, Aimone JB, Gage FH (2010). New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nature Reviews Neuroscience 11, 339-350.
    • (2010) Nature Reviews Neuroscience , vol.11 , pp. 339-350
    • Deng, W.1    Aimone, J.B.2    Gage, F.H.3
  • 14
    • 23244440196 scopus 로고    scopus 로고
    • The actin cytoskeleton: Integrating form and function at the synapse
    • DOI 10.1146/annurev.neuro.28.061604.135757
    • Dillon C, Goda Y (2005). The actin cytoskeleton : integrating form and function at the synapse. Annual Review of Neuroscience 28, 25-55. (Pubitemid 41098898)
    • (2005) Annual Review of Neuroscience , vol.28 , pp. 25-55
    • Dillon, C.1    Goda, Y.2
  • 15
    • 18844403842 scopus 로고    scopus 로고
    • Molecular mechanisms of dendritic spine development and remodeling
    • DOI 10.1016/j.pneurobio.2005.02.003, PII S0301008205000146
    • Ethell IM, Pasquale EB (2005). Molecular mechanisms of dendritic spine development and remodeling. Progress in Neurobiology 75, 161-205. (Pubitemid 40693130)
    • (2005) Progress in Neurobiology , vol.75 , Issue.3 , pp. 161-205
    • Ethell, I.M.1    Pasquale, E.B.2
  • 16
    • 28744449248 scopus 로고    scopus 로고
    • Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory
    • DOI 10.1016/j.neuron.2005.10.033, PII S0896627305009517
    • Fischer A, Sananbenesi F, Pang PT, Lu B, et al. (2005). Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory. Neuron 48, 825-838. (Pubitemid 41759432)
    • (2005) Neuron , vol.48 , Issue.5 , pp. 825-838
    • Fischer, A.1    Sananbenesi, F.2    Pang, P.T.3    Lu, B.4    Tsai, L.-H.5
  • 18
    • 70449584553 scopus 로고    scopus 로고
    • Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress
    • Hains AB, Vu MA, Maciejewski PK, van Dyck CH, et al. (2009). Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress. Proceedings of the National Academy of Sciences USA 106, 17957-17962.
    • (2009) Proceedings of the National Academy of Sciences USA , vol.106 , pp. 17957-17962
    • Hains, A.B.1    Vu, M.A.2    MacIejewski, P.K.3    Van Dyck, C.H.4
  • 19
    • 17144385440 scopus 로고    scopus 로고
    • Short-term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampus
    • DOI 10.1111/j.1460-9568.2005.03968.x
    • Hajszan T, MacLusky NJ, Leranth C (2005). Short-term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampus. European Journal of Neuroscience 21, 1299-1303. (Pubitemid 40516628)
    • (2005) European Journal of Neuroscience , vol.21 , Issue.5 , pp. 1299-1303
    • Hajszan, T.1    MacLusky, N.J.2    Leranth, C.3
  • 20
    • 65349087280 scopus 로고    scopus 로고
    • AMPA receptor trafficking pathways and links to dendritic spine morphogenesis
    • Hanley JG (2008). AMPA receptor trafficking pathways and links to dendritic spine morphogenesis. Cellular Adhesion and Migration 2, 276-282.
    • (2008) Cellular Adhesion and Migration , vol.2 , pp. 276-282
    • Hanley, J.G.1
  • 21
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • DOI 10.1126/science.1072994
    • Hardy J, Selkoe DJ (2002). The amyloid hypothesis of Alzheimer's disease : progress and problems on the road to therapeutics. Science 297, 353-356. (Pubitemid 34790756)
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 23
    • 33845411954 scopus 로고    scopus 로고
    • AMPAR removal underlies Aβ-Induced synaptic depression and dendritic spine loss
    • DOI 10.1016/j.neuron.2006.10.035, PII S0896627306008725
    • Hsieh H, Boehm J, Sato C, Iwatsubo T, et al. (2006). AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron 52, 831-843. (Pubitemid 44828454)
    • (2006) Neuron , vol.52 , Issue.5 , pp. 831-843
    • Hsieh, H.1    Boehm, J.2    Sato, C.3    Iwatsubo, T.4    Tomita, T.5    Sisodia, S.6    Malinow, R.7
  • 24
    • 13244279632 scopus 로고    scopus 로고
    • Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons
    • DOI 10.1038/nn1381
    • Ji Y, Pang PT, Feng L, Lu B (2005). Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons. Nature Neuroscience 8, 164-172. (Pubitemid 40194046)
    • (2005) Nature Neuroscience , vol.8 , Issue.2 , pp. 164-172
    • Ji, Y.1    Pang, P.T.2    Feng, L.3    Lu, B.4
  • 25
    • 18944406852 scopus 로고    scopus 로고
    • Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs
    • DOI 10.1016/j.molbrainres.2004.12.020, PII S0169328X04006345
    • Karege F, Vaudan G, Schwald M, Perroud N, et al. (2005). Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs. Molecular Brain Research 136, 29-37. (Pubitemid 40704606)
    • (2005) Molecular Brain Research , vol.136 , Issue.1-2 , pp. 29-37
    • Karege, F.1    Vaudan, G.2    Schwald, M.3    Perroud, N.4    La Harpe, R.5
  • 26
    • 5344244073 scopus 로고    scopus 로고
    • Translational regulatory mechanisms in persistent forms of synaptic plasticity
    • DOI 10.1016/j.neuron.2004.09.013, PII S0896627304006063
    • Kelleher IIIrd RJ, Govindarajan A, Tonegawa S (2004). Translational regulatory mechanisms in persistent forms of synaptic plasticity. Neuron 44, 59-73. (Pubitemid 39348830)
    • (2004) Neuron , vol.44 , Issue.1 , pp. 59-73
    • Kelleher III, R.J.1    Govindarajan, A.2    Tonegawa, S.3
  • 28
    • 50349083093 scopus 로고    scopus 로고
    • Dendritic spine loss and synaptic alterations in Alzheimer's disease
    • Knobloch M, Mansuy IM (2008). Dendritic spine loss and synaptic alterations in Alzheimer's disease. Molecular Neurobiology 37, 73-82.
    • (2008) Molecular Neurobiology , vol.37 , pp. 73-82
    • Knobloch, M.1    Mansuy, I.M.2
  • 29
    • 0027426029 scopus 로고
    • A cdc2-related kinase PSSALRE/cdk5 is homologous with the 30 kDa subunit of tau protein kinase II, a proline-directed protein kinase associated with microtubule
    • DOI 10.1016/0014-5793(93)80723-8
    • Kobayashi S, Ishiguro K, Omori A, Takamatsu M, et al. (1993). A cdc2-related kinase PSSALRE/cdk5 is homologous with the 30 kDa subunit of tau protein kinase II, a proline-directed protein kinase associated with microtubule. FEBS Letters 335, 171-175. (Pubitemid 23350401)
    • (1993) FEBS Letters , vol.335 , Issue.2 , pp. 171-175
    • Kobayashi, S.1    Ishiguro, K.2    Omori, A.3    Takamatsu, M.4    Arioka, M.5    Imahori, K.6    Uchida, T.7
  • 30
    • 0029021177 scopus 로고
    • Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor
    • Korte M, Carroll P, Wolf E, Brem G, et al. (1995). Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proceedings of the National Academy of Sciences USA 92, 8856-8860.
    • (1995) Proceedings of the National Academy of Sciences USA , vol.92 , pp. 8856-8860
    • Korte, M.1    Carroll, P.2    Wolf, E.3    Brem, G.4
  • 31
    • 54049133277 scopus 로고    scopus 로고
    • The molecular neurobiology of depression
    • Krishnan V, Nestler EJ (2008). The molecular neurobiology of depression. Nature 455, 894-902.
    • (2008) Nature , vol.455 , pp. 894-902
    • Krishnan, V.1    Nestler, E.J.2
  • 32
    • 77951653236 scopus 로고    scopus 로고
    • Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61
    • Kurup P, Zhang Y, Xu J, Venkitaramani DV, et al. (2010). Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61. Journal of Neuroscience 30, 5948-5957.
    • (2010) Journal of Neuroscience , vol.30 , pp. 5948-5957
    • Kurup, P.1    Zhang, Y.2    Xu, J.3    Venkitaramani, D.V.4
  • 33
    • 33846633336 scopus 로고    scopus 로고
    • Aβ oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
    • DOI 10.1523/JNEUROSCI.3501-06.2007
    • Lacor PN, Buniel MC, Furlow PW, Clemente AS, et al. (2007). Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. Journal of Neuroscience 27, 796-807. (Pubitemid 46174498)
    • (2007) Journal of Neuroscience , vol.27 , Issue.4 , pp. 796-807
    • Lacor, P.N.1    Buniel, M.C.2    Furlow, P.W.3    Clemente, A.S.4    Velasco, P.T.5    Wood, M.6    Viola, K.L.7    Klein, W.L.8
  • 34
    • 67651121690 scopus 로고    scopus 로고
    • Recent advances in understanding the roles of Cdk5 in synaptic plasticity
    • Lai KO, Ip NY (2009). Recent advances in understanding the roles of Cdk5 in synaptic plasticity. Biochimica et Biophysica Acta 1792, 741-745.
    • (2009) Biochimica et Biophysica Acta , vol.1792 , pp. 741-745
    • Lai, K.O.1    Ip, N.Y.2
  • 35
    • 34249099711 scopus 로고    scopus 로고
    • NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders
    • DOI 10.1038/nrn2153, PII NRN2153
    • Lau CG, Zukin RS (2007). NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders. Nature Reviews Neuroscience 8, 413-426. (Pubitemid 46789232)
    • (2007) Nature Reviews Neuroscience , vol.8 , Issue.6 , pp. 413-426
    • Lau, C.G.1    Zukin, R.S.2
  • 37
    • 33645095476 scopus 로고    scopus 로고
    • Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond
    • Lipton SA (2006). Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond. Nature Reviews Drug Discovery 5, 160-170.
    • (2006) Nature Reviews Drug Discovery , vol.5 , pp. 160-170
    • Lipton, S.A.1
  • 38
    • 33747070540 scopus 로고    scopus 로고
    • Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting
    • DOI 10.1523/JNEUROSCI.1184-06.2006
    • Liston C, Miller MM, Goldwater DS, Radley JJ, et al. (2006). Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting. Journal of Neuroscience 26, 7870-7874. (Pubitemid 44315156)
    • (2006) Journal of Neuroscience , vol.26 , Issue.30 , pp. 7870-7874
    • Liston, C.1    Miller, M.M.2    Goldwater, D.S.3    Radley, J.J.4    Rocher, A.B.5    Hof, P.R.6    Morrison, J.H.7    McEwen, B.S.8
  • 39
    • 23044488902 scopus 로고    scopus 로고
    • The yin and yang of neurotrophin action
    • DOI 10.1038/nrn1726
    • Lu B, Pang PT, Woo NH (2005). The yin and yang of neurotrophin action. Nature Reviews Neuroscience 6, 603-614. (Pubitemid 41059335)
    • (2005) Nature Reviews Neuroscience , vol.6 , Issue.8 , pp. 603-614
    • Lu, B.1    Pang, P.T.2    Woo, N.H.3
  • 40
    • 61649088370 scopus 로고    scopus 로고
    • NMDA receptor antagonist memantine promotes cell proliferation and production of mature granule neurons in the adult hippocampus
    • Maekawa M, Namba T, Suzuki E, Yuasa S, et al. (2009). NMDA receptor antagonist memantine promotes cell proliferation and production of mature granule neurons in the adult hippocampus. Neuroscience Research 63, 259-266.
    • (2009) Neuroscience Research , vol.63 , pp. 259-266
    • Maekawa, M.1    Namba, T.2    Suzuki, E.3    Yuasa, S.4
  • 41
    • 77951855933 scopus 로고    scopus 로고
    • Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents
    • Massa SM, Yang T, Xie Y, Shi J, et al. (2010). Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents. Journal of Clinical investigation 120, 1774-1785.
    • (2010) Journal of Clinical Investigation , vol.120 , pp. 1774-1785
    • Massa, S.M.1    Yang, T.2    Xie, Y.3    Shi, J.4
  • 45
    • 34948842904 scopus 로고    scopus 로고
    • Memantine: A NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system - Too little activation is bad, too much is even worse
    • DOI 10.1016/j.neuropharm.2007.07.013, PII S0028390807002298
    • Parsons CG, Stoffler A, Danysz W (2007). Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system-too little activation is bad, too much is even worse. Neuropharmacology 53, 699-723. (Pubitemid 47532143)
    • (2007) Neuropharmacology , vol.53 , Issue.6 , pp. 699-723
    • Parsons, C.G.1    Stoffler, A.2    Danysz, W.3
  • 46
    • 0041989616 scopus 로고    scopus 로고
    • Induction of dendritic spines by an extracellular domain of AMPA receptor subunit GluR2
    • DOI 10.1038/nature01781
    • Passafaro M, Nakagawa T, Sala C, Sheng M (2003). Induction of dendritic spines by an extracellular domain of AMPA receptor subunit GluR2. Nature 424, 677-681. (Pubitemid 36987992)
    • (2003) Nature , vol.424 , Issue.6949 , pp. 677-681
    • Passafaro, M.1    Nakagawa, T.2    Sala, C.3    Sheng, M.4
  • 47
    • 0030176079 scopus 로고    scopus 로고
    • Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice
    • DOI 10.1016/S0896-6273(00)80140-3
    • Patterson SL, Abel T, Deuel TA, Martin KC, et al. (1996). Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron 16, 1137-1145. (Pubitemid 26227235)
    • (1996) Neuron , vol.16 , Issue.6 , pp. 1137-1145
    • Patterson, S.L.1    Abel, T.2    Deuel, T.A.S.3    Martin, K.C.4    Rose, J.C.5    Kandel, E.R.6
  • 48
    • 36549030795 scopus 로고    scopus 로고
    • Stress, depression, and neuroplasticity: A convergence of mechanisms
    • DOI 10.1038/sj.npp.1301574, PII 1301574
    • Pittenger C, Duman RS (2008). Stress, depression, and neuroplasticity: a convergence of mechanisms. Neuropsychopharmacology 33, 88-109. (Pubitemid 350191319)
    • (2008) Neuropsychopharmacology , vol.33 , Issue.1 , pp. 88-109
    • Pittenger, C.1    Duman, R.S.2
  • 52
    • 0034192397 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) induces dendritic targeting of BDNF and tyrosine kinase B mRNAS in hippocampal neurons through a phosphatidylinositol-3 kinase-dependent pathway
    • Righi M, Tongiorgi E, Cattaneo A (2000). Brain-derived neurotrophic factor (BDNF) induces dendritic targeting of BDNF and tyrosine kinase B mRNAs in hippocampal neurons through a phosphatidylinositol-3 kinasedependent pathway. Journal of Neuroscience 20, 3165-3174. (Pubitemid 30263133)
    • (2000) Journal of Neuroscience , vol.20 , Issue.9 , pp. 3165-3174
    • Righi, M.1    Tongiorgi, E.2    Cattaneo, A.3
  • 53
    • 71849109591 scopus 로고    scopus 로고
    • Brainderived neurotrophic factor reduces amyloidogenic processing through control of SORLA gene expression
    • Rohe M, Synowitz M, Glass R, Paul SM, et al. (2009). Brainderived neurotrophic factor reduces amyloidogenic processing through control of SORLA gene expression. Journal of Neuroscience 29, 15472-15478.
    • (2009) Journal of Neuroscience , vol.29 , pp. 15472-15478
    • Rohe, M.1    Synowitz, M.2    Glass, R.3    Paul, S.M.4
  • 55
    • 37849050242 scopus 로고    scopus 로고
    • Neurotrophic factors in Alzheimer's disease: Role of axonal transport
    • Schindowski K, Belarbi K, Buee L (2008). Neurotrophic factors in Alzheimer's disease: role of axonal transport. Genes, Brain and Behavior 7 (Suppl. 1), 43-56.
    • (2008) Genes, Brain and Behavior , vol.7 , Issue.SUPPL. 1 , pp. 43-56
    • Schindowski, K.1    Belarbi, K.2    Buee, L.3
  • 56
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • DOI 10.1126/science.1074069
    • Selkoe DJ (2002). Alzheimer's disease is a synaptic failure. Science 298, 789-791. (Pubitemid 35231524)
    • (2002) Science , vol.298 , Issue.5594 , pp. 789-791
    • Selkoe, D.J.1
  • 57
    • 33947314641 scopus 로고    scopus 로고
    • Natural oligomers of the Alzheimer amyloid-β protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway
    • DOI 10.1523/JNEUROSCI.4970-06.2007
    • Shankar GM, Bloodgood BL, Townsend M, Walsh DM, et al. (2007). Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptordependent signaling pathway. Journal of Neuroscience 27, 2866-2875. (Pubitemid 46438992)
    • (2007) Journal of Neuroscience , vol.27 , Issue.11 , pp. 2866-2875
    • Shankar, G.M.1    Bloodgood, B.L.2    Townsend, M.3    Walsh, D.M.4    Selkoe, D.J.5    Sabatini, B.L.6
  • 58
    • 0042625002 scopus 로고    scopus 로고
    • Decreased dendritic spine density on prefrontal cortical and hippocampal pyramidal neurons in postweaning social isolation rats
    • DOI 10.1016/S0006-8993(03)03042-7
    • Silva-Gomez AB, Rojas D, Juarez I, Flores G (2003). Decreased dendritic spine density on prefrontal cortical and hippocampal pyramidal neurons in postweaning social isolation rats. Brain Research 983, 128-136. (Pubitemid 36957950)
    • (2003) Brain Research , vol.983 , Issue.1-2 , pp. 128-136
    • Silva-Gomez, A.B.1    Rojas, D.2    Juarez, I.3    Flores, G.4
  • 60
    • 77951869291 scopus 로고    scopus 로고
    • Association of anxiety and depression with microtubule-associated protein 2-and synaptopodinimmunolabeled dendrite and spine densities in hippocampal CA3 of older humans
    • Soetanto A, Wilson RS, Talbot K, Un A, et al. (2010). Association of anxiety and depression with microtubule-associated protein 2-and synaptopodinimmunolabeled dendrite and spine densities in hippocampal CA3 of older humans. Archives of General Psychiatry 67, 448-457.
    • (2010) Archives of General Psychiatry , vol.67 , pp. 448-457
    • Soetanto, A.1    Wilson, R.S.2    Talbot, K.3    Un, A.4
  • 61
    • 23444448170 scopus 로고    scopus 로고
    • Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy
    • DOI 10.1523/JNEUROSCI.1879-05.2005
    • Spires TL, Meyer-Luehmann M, Stern EA, McLean PJ, et al. (2005). Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy. Journal of Neuroscience 25, 7278-7287. (Pubitemid 41113944)
    • (2005) Journal of Neuroscience , vol.25 , Issue.31 , pp. 7278-7287
    • Spires, T.L.1    Meyer-Luehmann, M.2    Stern, E.A.3    McLean, P.J.4    Skoch, J.5    Nguyen, P.T.6    Bacskai, B.J.7    Hyman, B.T.8
  • 62
    • 32344435520 scopus 로고    scopus 로고
    • Molecular mechanisms of dendritic spine morphogenesis
    • DOI 10.1016/j.conb.2005.12.001, PII S0959438805001832, Development
    • Tada T, Sheng M (2006). Molecular mechanisms of dendritic spine morphogenesis. Current Opinion in Neurobiology 16, 95-101. (Pubitemid 43221859)
    • (2006) Current Opinion in Neurobiology , vol.16 , Issue.1 , pp. 95-101
    • Tada, T.1    Sheng, M.2
  • 63
    • 41149120733 scopus 로고    scopus 로고
    • Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines
    • DOI 10.1126/science.1152864
    • Tanaka J, Horiike Y, Matsuzaki M, Miyazaki T, et al. (2008). Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines. Science 319, 1683-1687. (Pubitemid 351432509)
    • (2008) Science , vol.319 , Issue.5870 , pp. 1683-1687
    • Tanaka, J.-I.1    Horiike, Y.2    Matsuzaki, M.3    Miyazaki, T.4    Ellis-Davies, G.C.R.5    Kasai, H.6
  • 65
    • 0031439983 scopus 로고    scopus 로고
    • Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons
    • Tongiorgi E, Righi M, Cattaneo A (1997). Activitydependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons. Journal of Neuroscience 17, 9492-9505. (Pubitemid 28006394)
    • (1997) Journal of Neuroscience , vol.17 , Issue.24 , pp. 9492-9505
    • Tongiorgi, E.1    Righi, M.2    Cattaneo, A.3
  • 67
    • 68249117473 scopus 로고    scopus 로고
    • New insights into the role of brain-derived neurotrophic factor in synaptic plasticity
    • Waterhouse EG, Xu B (2009). New insights into the role of brain-derived neurotrophic factor in synaptic plasticity. Molecular and Cellular Neuroscience 42, 81-89.
    • (2009) Molecular and Cellular Neuroscience , vol.42 , pp. 81-89
    • Waterhouse, E.G.1    Xu, B.2
  • 68
    • 75549092259 scopus 로고    scopus 로고
    • Amyloid beta from axons and dendrites reduces local spine number and plasticity
    • Wei W, Nguyen LN, Kessels HW, Hagiwara H, et al. (2010). Amyloid beta from axons and dendrites reduces local spine number and plasticity. Nature Neuroscience 13, 190-196.
    • (2010) Nature Neuroscience , vol.13 , pp. 190-196
    • Wei, W.1    Nguyen, L.N.2    Kessels, H.W.3    Hagiwara, H.4
  • 72
    • 38349009068 scopus 로고    scopus 로고
    • Cdk5 regulates the phosphorylation of tyrosine 1472 NR2B and the surface expression of NMDA receptors
    • Zhang S, Edelmann L, Liu J, Crandall JE, et al. (2008). Cdk5 regulates the phosphorylation of tyrosine 1472 NR2B and the surface expression of NMDA receptors. Journal of Neuroscience 28, 415-424.
    • (2008) Journal of Neuroscience , vol.28 , pp. 415-424
    • Zhang, S.1    Edelmann, L.2    Liu, J.3    Crandall, J.E.4
  • 73
    • 9644278075 scopus 로고    scopus 로고
    • Shrinkage of dendritic spines associated with long-term depression of hippocampal synapses
    • DOI 10.1016/j.neuron.2004.11.011, PII S0896627304007226
    • Zhou Q, Homma KJ, Poo MM (2004). Shrinkage of dendritic spines associated with long-term depression of hippocampal synapses. Neuron 44, 749-757. (Pubitemid 39575629)
    • (2004) Neuron , vol.44 , Issue.5 , pp. 749-757
    • Zhou, Q.1    Homma, K.J.2    Poo, M.-M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.