메뉴 건너뛰기




Volumn 20, Issue 10, 2011, Pages 1515-1527

Multitract microtransplantation increases the yield of DARPP-32-positive embryonic striatal cells in a rodent model of huntington's disease

Author keywords

Embryonic striatal neurons; Green fluorescent protein (GFP); Huntington's disease model; Microtransplantation; Multitract

Indexed keywords

GREEN FLUORESCENT PROTEIN; PHOSPHOPROTEIN DARPP 32;

EID: 84856061919     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368910X547435     Document Type: Article
Times cited : (14)

References (57)
  • 1
    • 0023777777 scopus 로고
    • Development of intracerebral dopaminergic grafts: A combined immunohistochemical and autoradiographic study of its time course and environmental influences
    • Abrous, N.; Guy, J.; Vigny, A.; Calas, A.; Le Moal, M.; Herman, J. P. Development of intracerebral dopaminergic grafts: A combined immunohistochemical and autoradiographic study of its time course and environmental influences. J. Comp. Neurol. 273:26-41; 1988.
    • (1988) J. Comp. Neurol , vol.273 , pp. 26-41
    • Abrous, N.1    Guy, J.2    Vigny, A.3    Calas, A.4    le Moal, M.5    Herman, J.P.6
  • 2
    • 0036094145 scopus 로고    scopus 로고
    • Neuroprotection by neurotrophins and GDNF family members in the excitotoxic model of Huntington's disease
    • Alberch, J.; Pérez-Navarro, E.; Canals, J. M. Neuroprotection by neurotrophins and GDNF family members in the excitotoxic model of Huntington's disease. Brain Res. Bull. 57:817-822; 2002.
    • (2002) Brain Res. Bull , vol.57 , pp. 817-822
    • Alberch, J.1    Pérez-Navarro, E.2    Canals, J.M.3
  • 3
    • 0028872501 scopus 로고
    • Time course of ciliary neurotrophic factor 1526 mRNA expression is coincident with the presence of protoplasmic astrocytes in traumatized rat striatum
    • Asada, H.; Ip, N. Y.; Pan, L.; Razack, N.; Parfitt, M. M.; Plunkett, R. J. Time course of ciliary neurotrophic factor 1526 mRNA expression is coincident with the presence of protoplasmic astrocytes in traumatized rat striatum. J. Neurosci. Res. 40:22-30; 1995.
    • (1995) J. Neurosci. Res , vol.40 , pp. 22-30
    • Asada, H.1    Ip, N.Y.2    Pan, L.3    Razack, N.4    Parfitt, M.M.5    Plunkett, R.J.6
  • 4
    • 55949130712 scopus 로고    scopus 로고
    • Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats
    • Aubry, L.; Bugi, A.; Lefort, N.; Rousseau, F.; Peschanski, M.; Perrier, A. L. Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats. Proc. Natl. Acad. Sci. USA 105:16707-16712; 2008.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 16707-16712
    • Aubry, L.1    Bugi, A.2    Lefort, N.3    Rousseau, F.4    Peschanski, M.5    Perrier, A.L.6
  • 5
    • 70449698433 scopus 로고    scopus 로고
    • Neural grafts in Huntington's disease: Viability after 10 years
    • Bachoud-Lévi, A. Neural grafts in Huntington's disease: Viability after 10 years. Lancet Neurol. 8:979-981; 2009.
    • (2009) Lancet Neurol , vol.8 , pp. 979-981
    • Bachoud-Lévi, A.1
  • 8
    • 0033104019 scopus 로고    scopus 로고
    • Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor
    • Batchelor, P. E.; Liberatore, G. T.; Wong, J. Y.; Porritt, M. J.; Frerichs, F.; Donnan, G. A.; Howells, D. W. Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor. J. Neurosci. 19:1708-1716; 1999.
    • (1999) J. Neurosci , vol.19 , pp. 1708-1716
    • Batchelor, P.E.1    Liberatore, G.T.2    Wong, J.Y.3    Porritt, M.J.4    Frerichs, F.5    Donnan, G.A.6    Howells, D.W.7
  • 9
    • 0031907280 scopus 로고    scopus 로고
    • Timedependent expression of donorand host-specific major histocompatibility complex class I and II antigens in allogeneic dopamine-rich macroand micrografts: Comparison of two different grafting protocols
    • Brandis, A.; Kuder, H.; Knappe, U.; Jödicke, A.; Schönmayr, R.; Samii, M.; Walter, G. F.; Nikkhah, G. Timedependent expression of donorand host-specific major histocompatibility complex class I and II antigens in allogeneic dopamine-rich macroand micrografts: Comparison of two different grafting protocols. Acta Neuropathol. 95:85-97; 1998.
    • (1998) Acta Neuropathol , vol.95 , pp. 85-97
    • Brandis, A.1    Kuder, H.2    Knappe, U.3    Jödicke, A.4    Schönmayr, R.5    Samii, M.6    Walter, G.F.7    Nikkhah, G.8
  • 12
    • 0032443679 scopus 로고    scopus 로고
    • Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 after excitotoxicity in a rat model of Huntington's disease
    • Canals, J. M.; Marco, S.; Checa, N.; Michels, A.; PrezNavarro, E.; Arenas, E.; Alberch, J. Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 after excitotoxicity in a rat model of Huntington's disease. Neurobiol. Dis. 5:357-364; 1998.
    • (1998) Neurobiol. Dis , vol.5 , pp. 357-364
    • Canals, J.M.1    Marco, S.2    Checa, N.3    Michels, A.4    Preznavarro, E.5    Arenas, E.6    Alberch, J.7
  • 14
    • 0021995997 scopus 로고
    • Depletion of unilateral striatal dopamine impairs initiation of contralateral actions and not sensory attention
    • Carli, M.; Evenden, J. L.; Robbins, T. W. Depletion of unilateral striatal dopamine impairs initiation of contralateral actions and not sensory attention. Nature 313:679682; 1985.
    • (1985) Nature , vol.313 , pp. 679682
    • Carli, M.1    Evenden, J.L.2    Robbins, T.W.3
  • 16
    • 0022607703 scopus 로고
    • Anatomical predictors of behavioral recovery following fetal striatal transplants
    • Deckel, A. W.; Moran, T. H.; Coyle, J. T.; Sanberg, P. R.; Robinson, R. G. Anatomical predictors of behavioral recovery following fetal striatal transplants. Brain Res. 365:249-258; 1986.
    • (1986) Brain Res , vol.365 , pp. 249-258
    • Deckel, A.W.1    Moran, T.H.2    Coyle, J.T.3    Sanberg, P.R.4    Robinson, R.G.5
  • 17
    • 17044421696 scopus 로고    scopus 로고
    • Training specificity, graft JIANG ET AL. development and graft-mediated functional recovery in a rodent model of Huntington's disease
    • Dobrossy, M. D.; Dunnett, S. Training specificity, graft JIANG ET AL. development and graft-mediated functional recovery in a rodent model of Huntington's disease. Neuroscience 132: 543-552; 2005.
    • (2005) Neuroscience , vol.132 , pp. 543-552
    • Dobrossy, M.D.1    Dunnett, S.2
  • 18
    • 33845629441 scopus 로고    scopus 로고
    • Morphological and cellular changes within embryonic striatal grafts associated with enriched environment and involuntary exercise
    • Dobrossy, M. D.; Dunnett, S. B. Morphological and cellular changes within embryonic striatal grafts associated with enriched environment and involuntary exercise. Eur. J. Neurosci. 24:3223-3233; 2006.
    • (2006) Eur. J. Neurosci , vol.24 , pp. 3223-3233
    • Dobrossy, M.D.1    Dunnett, S.B.2
  • 19
    • 60549107347 scopus 로고    scopus 로고
    • Environmental housing and duration of exposure affect striatal graft morphology in a rodent model of Huntington's disease
    • Dobrossy, M. D.; Dunnett, S. B. Environmental housing and duration of exposure affect striatal graft morphology in a rodent model of Huntington's disease. Cell Transplant. 17:1125-1134; 2008.
    • (2008) Cell Transplant , vol.17 , pp. 1125-1134
    • Dobrossy, M.D.1    Dunnett, S.B.2
  • 20
    • 0031927150 scopus 로고    scopus 로고
    • Quinolinic acid-induced inflammation in the striatum does not impair the survival of neural allografts in the rat
    • Duan, W.; Widner, H.; Cameron, R. M.; Brundin, P. Quinolinic acid-induced inflammation in the striatum does not impair the survival of neural allografts in the rat. Eur. J. Neurosci. 10:2595-2606; 1998.
    • (1998) Eur. J. Neurosci , vol.10 , pp. 2595-2606
    • Duan, W.1    Widner, H.2    Cameron, R.M.3    Brundin, P.4
  • 21
    • 0024542379 scopus 로고
    • Nimodipine enhances growth and vascularization of neural grafts
    • Finger, S.; Dunnett, S. B. Nimodipine enhances growth and vascularization of neural grafts. Exp. Neurol. 104: 1-9; 1989.
    • (1989) Exp. Neurol , vol.104 , pp. 1-9
    • Finger, S.1    Dunnett, S.B.2
  • 22
    • 34247236661 scopus 로고    scopus 로고
    • GFPtransgenic Lewis rats as a cell source for oligodendrocyte replacement
    • Francis, J. S.; Olariu, A.; Kobayashi, E.; Leone, P. GFPtransgenic Lewis rats as a cell source for oligodendrocyte replacement. Exp. Neurol. 205:177-189; 2007.
    • (2007) Exp. Neurol , vol.205 , pp. 177-189
    • Francis, J.S.1    Olariu, A.2    Kobayashi, E.3    Leone, P.4
  • 23
    • 0030801494 scopus 로고    scopus 로고
    • The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. I. Morphological characteristics
    • Fricker, R. A.; Torres, E. M.; Dunnett, S. B. The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. I. Morphological characteristics. Neuroscience 79:695-710; 1997.
    • (1997) Neuroscience , vol.79 , pp. 695-710
    • Fricker, R.A.1    Torres, E.M.2    Dunnett, S.B.3
  • 24
    • 0030754874 scopus 로고    scopus 로고
    • The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. II. Correlation between positron emission tomography and reaching behaviour
    • Fricker, R. A.; Torres, E. M.; Hume, S. P.; Myers, R.; Opacka-Juffrey, J.; Ashworth, S.; Brooks, D. J.; Dunnett, S. B. The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. II. Correlation between positron emission tomography and reaching behaviour. Neuroscience 79:711-721; 1997.
    • (1997) Neuroscience , vol.79 , pp. 711-721
    • Fricker, R.A.1    Torres, E.M.2    Hume, S.P.3    Myers, R.4    Opacka-Juffrey, J.5    Ashworth, S.6    Brooks, D.J.7    Dunnett, S.B.8
  • 25
    • 1242295351 scopus 로고    scopus 로고
    • Striatal neurons in striatal grafts are derived from both post-mitotic cells and dividing progenitors
    • Fricker-Gates, R. A.; White, A.; Gates, M. A.; Dunnett, S. B. Striatal neurons in striatal grafts are derived from both post-mitotic cells and dividing progenitors. Eur. J. Neurosci. 19:513-520; 2004.
    • (2004) Eur. J. Neurosci , vol.19 , pp. 513-520
    • Fricker-Gates, R.A.1    White, A.2    Gates, M.A.3    Dunnett, S.B.4
  • 27
    • 0031264356 scopus 로고    scopus 로고
    • Regulation of astroglial-derived dopaminergic neurotrophic factors by interleukin-1β in the striatum of young and middle-aged mice
    • Ho, A. Regulation of astroglial-derived dopaminergic neurotrophic factors by interleukin-1β in the striatum of young and middle-aged mice. Exp. Neurol. 148:348-359; 1997.
    • (1997) Exp. Neurol , vol.148 , pp. 348-359
    • Ho, A.1
  • 29
    • 0022551746 scopus 로고
    • Graft-induced behavioral recovery in an animal model of Huntington disease
    • Isacson, O.; Dunnett, S. B.; Bjrklund, A. Graft-induced behavioral recovery in an animal model of Huntington disease. Proc. Natl. Acad. Sci. USA 83:2728-2732; 1986.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 2728-2732
    • Isacson, O.1    Dunnett, S.B.2    Bjrklund, A.3
  • 30
    • 63049113624 scopus 로고    scopus 로고
    • Ketamine anaesthesia interferes with the quinolinic acid-induced lesion in a rat model of Huntington's disease
    • Jiang, W.; Buchele, F.; Papazoglou, A.; Dobrossy, M.; Nikkhah, G. Ketamine anaesthesia interferes with the quinolinic acid-induced lesion in a rat model of Huntington's disease. J. Neurosci. Methods 179:219-223; 2009.
    • (2009) J. Neurosci. Methods , vol.179 , pp. 219-223
    • Jiang, W.1    Buchele, F.2    Papazoglou, A.3    Dobrossy, M.4    Nikkhah, G.5
  • 31
    • 0030612387 scopus 로고    scopus 로고
    • Co-localization of the D1 dopamine receptor in a subset of DARPP-32-containing neurons in rat caudate-putamen
    • Langley, K. C.; Bergson, C.; Greengard, P.; Ouimet, C. C. Co-localization of the D1 dopamine receptor in a subset of DARPP-32-containing neurons in rat caudate-putamen. Neuroscience 78:977-983; 1997.
    • (1997) Neuroscience , vol.78 , pp. 977-983
    • Langley, K.C.1    Bergson, C.2    Greengard, P.3    Ouimet, C.C.4
  • 32
    • 38049101110 scopus 로고    scopus 로고
    • Transplantation of adult neural progenitor cells transfected with vascular endothelial growth factor rescues grafted cells in the rat brain
    • Maurer, M. H.; Thomas, C.; Brgers, H. F.; Kuschinsky, W. Transplantation of adult neural progenitor cells transfected with vascular endothelial growth factor rescues grafted cells in the rat brain. Int. J. Biol. Sci. 4:1-7; 2008.
    • (2008) Int. J. Biol. Sci , vol.4 , pp. 1-7
    • Maurer, M.H.1    Thomas, C.2    Brgers, H.F.3    Kuschinsky, W.4
  • 33
    • 0028040712 scopus 로고
    • Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons
    • Mizuno, K.; Carnahan, J.; Nawa, H. Brain-derived neurotrophic factor promotes differentiation of striatal GABAergic neurons. Dev. Biol. 165:243-256; 1994.
    • (1994) Dev. Biol , vol.165 , pp. 243-256
    • Mizuno, K.1    Carnahan, J.2    Nawa, H.3
  • 34
    • 0033933449 scopus 로고    scopus 로고
    • Pretreatment with MK-801 or the lazaroid U-83836E does not enhance striatal graft survival
    • Mundt-Petersen, U.; Karlsson, J.; Schierle, G. S.; Brundin, P. Pretreatment with MK-801 or the lazaroid U-83836E does not enhance striatal graft survival. Cell Transplant. 9:73-78; 2000.
    • (2000) Cell Transplant , vol.9 , pp. 73-78
    • Mundt-Petersen, U.1    Karlsson, J.2    Schierle, G.S.3    Brundin, P.4
  • 36
    • 0028850676 scopus 로고
    • Trophic and protective actions of brain-derived neurotrophic factor on striatal DARPP-32-containing neurons in vitro
    • Nakao, N.; Brundin, P.; Funa, K.; Lindvall, O.; Odin, P. Trophic and protective actions of brain-derived neurotrophic factor on striatal DARPP-32-containing neurons in vitro. Brain Res. Dev. Brain Res. 90:92-101; 1995.
    • (1995) Brain Res. Dev. Brain Res , vol.90 , pp. 92-101
    • Nakao, N.1    Brundin, P.2    Funa, K.3    Lindvall, O.4    Odin, P.5
  • 37
    • 0030271245 scopus 로고    scopus 로고
    • DARPP-32-rich zones in grafts of lateral ganglionic eminence govern the extent of functional recovery in skilled paw reaching in an animal model of Huntington's disease
    • Nakao, N.; Grasbon-Frodl, E. M.; Widner, H.; Brundin, P. DARPP-32-rich zones in grafts of lateral ganglionic eminence govern the extent of functional recovery in skilled paw reaching in an animal model of Huntington's disease. Neuroscience 74:959-970; 1996.
    • (1996) Neuroscience , vol.74 , pp. 959-970
    • Nakao, N.1    Grasbon-Frodl, E.M.2    Widner, H.3    Brundin, P.4
  • 38
    • 0034015127 scopus 로고    scopus 로고
    • Fetal tissue transplants in animal models of Huntington's disease: The effects on damaged neuronal circuitry and behavioral deficits
    • Nakao, N.; Itakura, T. Fetal tissue transplants in animal models of Huntington's disease: The effects on damaged neuronal circuitry and behavioral deficits. Prog. Neurobiol. 61:313-338; 2000.
    • (2000) Prog. Neurobiol , vol.61 , pp. 313-338
    • Nakao, N.1    Itakura, T.2
  • 39
    • 0028955116 scopus 로고
    • Protective effects of BDNF and NT-3 but not PDGF against hypoglycemic injury to cultured striatal neurons
    • Nakao, N.; Kokaia, Z.; Odin, P.; Lindvall, O. Protective effects of BDNF and NT-3 but not PDGF against hypoglycemic injury to cultured striatal neurons. Exp. Neurol. 131(1):1-10; 1995.
    • (1995) Exp. Neurol , vol.131 , Issue.1 , pp. 1-10
    • Nakao, N.1    Kokaia, Z.2    Odin, P.3    Lindvall, O.4
  • 40
    • 0029917735 scopus 로고    scopus 로고
    • Brundin, P. Differential trophic effects of basic fibroblast growth factor, insulinlike growth factor-1, and neurotrophin-3 on striatal neurons in culture
    • Nakao, N.; Odin, P.; Lindvall, O.; Brundin, P. Differential trophic effects of basic fibroblast growth factor, insulinlike growth factor-1, and neurotrophin-3 on striatal neurons in culture. Exp. Neurol. 138:144-157; 1996.
    • (1996) Exp. Neurol , vol.138 , pp. 144-157
    • Nakao, N.1    Odin, P.2    Lindvall, O.3
  • 41
    • 0028084486 scopus 로고
    • Improved graft survival and striatal reinnervation by microtransplantation of fetal nigral cell suspensions in the rat Parkinson model
    • Nikkhah, G.; Cunningham, M. G.; Jodicke, A.; Knappe, U.; Bjorklund, A. Improved graft survival and striatal reinnervation by microtransplantation of fetal nigral cell suspensions in the rat Parkinson model. Brain Res. 633: 133-143; 1994.
    • (1994) Brain Res , vol.633 , pp. 133-143
    • Nikkhah, G.1    Cunningham, M.G.2    Jodicke, A.3    Knappe, U.4    Bjorklund, A.5
  • 42
    • 0028138846 scopus 로고
    • A microtransplantation approach for cell suspension grafting in the rat Parkinson model: A detailed account of the methodology
    • Nikkhah, G.; Olsson, M.; Eberhard, J.; Bentlage, C.; Cunningham, M. G.; Bjorklund, A. A microtransplantation approach for cell suspension grafting in the rat Parkinson model: A detailed account of the methodology. Neuroscience 63:57-72; 1994.
    • (1994) Neuroscience , vol.63 , pp. 57-72
    • Nikkhah, G.1    Olsson, M.2    Eberhard, J.3    Bentlage, C.4    Cunningham, M.G.5    Bjorklund, A.6
  • 43
    • 65849389930 scopus 로고    scopus 로고
    • Microtransplantation of dopaminergic cell suspensions: Further characterization and optimization of grafting parameters
    • Nikkhah, G.; Rosenthal, C.; Falkenstein, G.; Roedter, A.; Papazoglou, A.; Brandis, A. Microtransplantation of dopaminergic cell suspensions: Further characterization and optimization of grafting parameters. Cell Transplant. 18: 119-133; 2009.
    • (2009) Cell Transplant , vol.18 , pp. 119-133
    • Nikkhah, G.1    Rosenthal, C.2    Falkenstein, G.3    Roedter, A.4    Papazoglou, A.5    Brandis, A.6
  • 44
    • 0002573716 scopus 로고    scopus 로고
    • Microtransplantation of nigral dopamine neurons: A "step-bystep" recipe
    • Dunnett, S. B.; Baker, G., eds., Totowa, NJ: Humana Press Inc
    • Nikkhah, G.; Winkler, C.; Roedter, A.; Samii, M. Microtransplantation of nigral dopamine neurons: A "step-bystep" recipe. In: Dunnett, S. B.; Baker, G., eds. Cell and tissue transplantation in the CNS. Totowa, NJ: Humana Press Inc.; 2000:207-231. 1527
    • (2000) Cell and Tissue Transplantation In the CNS , pp. 207-231
    • Nikkhah, G.1    Winkler, C.2    Roedter, A.3    Samii, M.4
  • 45
    • 0015441424 scopus 로고
    • Early prenatal ontogeny of central monoamine neurons in the rat: Fluorescence histochemical observations
    • Olson, L.; Seiger, A. Early prenatal ontogeny of central monoamine neurons in the rat: Fluorescence histochemical observations. Z. Anat. Entwicklungsgesch. 137:301-316; 1972.
    • (1972) Z. Anat. Entwicklungsgesch , vol.137 , pp. 301-316
    • Olson, L.1    Seiger, A.2
  • 46
    • 0025058578 scopus 로고
    • Distribution of DARPP-32 in the basal ganglia: An electron microscopic study
    • Ouimet, C. C.; Greengard, P. Distribution of DARPP-32 in the basal ganglia: An electron microscopic study. J. Neurocytol. 19:39-52; 1990.
    • (1990) J. Neurocytol , vol.19 , pp. 39-52
    • Ouimet, C.C.1    Greengard, P.2
  • 47
    • 0032764083 scopus 로고    scopus 로고
    • Effects of ciliary neurotrophic factor on excitotoxicity and calcium-ionophore A23187induced cell death in cultured embryonic striatal neurons
    • Petersén, A.; Brundin, P. Effects of ciliary neurotrophic factor on excitotoxicity and calcium-ionophore A23187induced cell death in cultured embryonic striatal neurons. Exp. Neurol. 160:402-412; 1999.
    • (1999) Exp. Neurol , vol.160 , pp. 402-412
    • Petersén, A.1    Brundin, P.2
  • 48
    • 0345148384 scopus 로고    scopus 로고
    • Impact of a preceding striatal excitotoxic lesion and treatment with ciliary neurotrophic factor on striatal graft survival
    • Petersén, A.; Emgård, M.; Brundin, P. Impact of a preceding striatal excitotoxic lesion and treatment with ciliary neurotrophic factor on striatal graft survival. Brain Res. Bull. 50:275-281; 1999.
    • (1999) Brain Res. Bull , vol.50 , pp. 275-281
    • Petersén, A.1    Emgård, M.2    Brundin, P.3
  • 49
    • 0015810881 scopus 로고
    • Late prenatal ontogeny of central monoamine neurons in the rat: Fluorescence histochemical observations
    • Seiger, A.; Olson, L. Late prenatal ontogeny of central monoamine neurons in the rat: Fluorescence histochemical observations. Z. Anat. Entwicklungsgesch. 140:281-318; 1973.
    • (1973) Z. Anat. Entwicklungsgesch , vol.140 , pp. 281-318
    • Seiger, A.1    Olson, L.2
  • 50
    • 0033453218 scopus 로고    scopus 로고
    • Dopamine cells in nigral grafts differentiate prior to implantation
    • Sinclair, S. R.; Fawcett, J. W.; Dunnett, S. B. Dopamine cells in nigral grafts differentiate prior to implantation. Eur. J. Neurosci. 11:4341-4348; 1999.
    • (1999) Eur. J. Neurosci , vol.11 , pp. 4341-4348
    • Sinclair, S.R.1    Fawcett, J.W.2    Dunnett, S.B.3
  • 51
    • 0041906554 scopus 로고    scopus 로고
    • Strategies for the augmentation of grafted dopamine neuron survival
    • Sortwell, C. E. Strategies for the augmentation of grafted dopamine neuron survival. Front. Biosci. 8:522-532; 2003.
    • (2003) Front. Biosci , vol.8 , pp. 522-532
    • Sortwell, C.E.1
  • 52
    • 39749112525 scopus 로고    scopus 로고
    • Survival and functional recovery of transplanted human dopaminergic neurons into hemiparkinsonian rats depend on the cannula size of the implantation instrument
    • Steiner, B.; Winter, C.; Blumensath, S.; Paul, G.; Harnack, D.; Nikkhah, G.; Kupsch, A. Survival and functional recovery of transplanted human dopaminergic neurons into hemiparkinsonian rats depend on the cannula size of the implantation instrument. J. Neurosci. Methods 169:128134; 2008.
    • (2008) J. Neurosci. Methods , vol.169 , pp. 128134
    • Steiner, B.1    Winter, C.2    Blumensath, S.3    Paul, G.4    Harnack, D.5    Nikkhah, G.6    Kupsch, A.7
  • 53
    • 0028800803 scopus 로고
    • The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro
    • Ventimiglia, R.; Mather, P. E.; Jones, B. E.; Lindsay, R. M. The neurotrophins BDNF, NT-3 and NT-4/5 promote survival and morphological and biochemical differentiation of striatal neurons in vitro. Eur. J. Neurosci. 7: 213-222; 1995.
    • (1995) Eur. J. Neurosci , vol.7 , pp. 213-222
    • Ventimiglia, R.1    Mather, P.E.2    Jones, B.E.3    Lindsay, R.M.4
  • 54
    • 0034064954 scopus 로고    scopus 로고
    • Embryonic donor age and dissection influences striatal graft development and functional integration in a rodent model of Huntington's disease
    • Watts, C.; Brasted, P. J.; Dunnett, S. B. Embryonic donor age and dissection influences striatal graft development and functional integration in a rodent model of Huntington's disease. Exp. Neurol. 163:85-97; 2000.
    • (2000) Exp. Neurol , vol.163 , pp. 85-97
    • Watts, C.1    Brasted, P.J.2    Dunnett, S.B.3
  • 55
    • 0031768858 scopus 로고    scopus 로고
    • The development of intracerebral cell-suspension implants is influenced by the grafting medium
    • Watts, C.; Caldwell, M. A.; Dunnett, S. B. The development of intracerebral cell-suspension implants is influenced by the grafting medium. Cell Transplant. 7:573583; 1998.
    • (1998) Cell Transplant , vol.7 , pp. 573583
    • Watts, C.1    Caldwell, M.A.2    Dunnett, S.B.3
  • 56
    • 0031815611 scopus 로고    scopus 로고
    • Effects of severity of host striatal damage on the morphological development of intrastriatal transplants in a rodent model of Huntington's disease: Implications for timing of surgical intervention
    • Watts, C.; Dunnett, S. B. Effects of severity of host striatal damage on the morphological development of intrastriatal transplants in a rodent model of Huntington's disease: Implications for timing of surgical intervention. J. Neurosurg. 89:267-274; 1998.
    • (1998) J. Neurosurg , vol.89 , pp. 267-274
    • Watts, C.1    Dunnett, S.B.2
  • 57
    • 0034026851 scopus 로고    scopus 로고
    • Towards a protocol for the preparation and delivery of striatal tissue for clinical trials of transplantation in Huntington's disease
    • Watts, C.; Dunnett, S. B. Towards a protocol for the preparation and delivery of striatal tissue for clinical trials of transplantation in Huntington's disease. Cell Transplant. 9:223-234; 2000.
    • (2000) Cell Transplant , vol.9 , pp. 223-234
    • Watts, C.1    Dunnett, S.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.