-
1
-
-
0036337768
-
IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13
-
DOI 10.1016/S1074-7613(02)00332-1
-
Fallon, P. G., H. E. Jolin, P. Smith, C. L. Emson, M. J. Townsend, R. Fallon, P. Smith, and A. N. McKenzie. 2002. IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13. Immunity 17: 7-17. (Pubitemid 34874614)
-
(2002)
Immunity
, vol.17
, Issue.1
, pp. 7-17
-
-
Fallon, P.G.1
Jolin, H.E.2
Smith, P.3
Emson, C.L.4
Townsend, M.J.5
Fallon, R.6
Smith, P.7
McKenzie, A.N.J.8
-
2
-
-
16044371529
-
Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: Lymphocytic and eosinophilic inflammation without airway hyperreactivity
-
DOI 10.1073/pnas.93.15.7821
-
Rankin, J. A., D. E. Picarella, G. P. Geba, U. A. Temann, B. Prasad, B. DiCosmo, A. Tarallo, B. Stripp, J. Whitsett, and R. A. Flavell. 1996. Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc. Natl. Acad. Sci. USA 93: 7821-7825. (Pubitemid 26277122)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.15
, pp. 7821-7825
-
-
Rankin, J.A.1
Picarella, D.E.2
Geba, G.P.3
Temann, U.-A.4
Prasad, B.5
Dicosmo, B.6
Tarallo, A.7
Stripp, B.8
Whitsett, J.9
Flavell, R.A.10
-
3
-
-
0035888013
-
Critical role for IL-13 in the development of allergen-induced airway hyperreactivity
-
Walter, D. M., J. J. McIntire, G. Berry, A. N. McKenzie, D. D. Donaldson, R. H. DeKruyff, and D. T. Umetsu. 2001. Critical role for IL-13 in the development of allergen-induced airway hyperreactivity. J. Immunol. 167: 4668-4675. (Pubitemid 32954348)
-
(2001)
Journal of Immunology
, vol.167
, Issue.8
, pp. 4668-4675
-
-
Walter, D.M.1
McIntire, J.J.2
Berry, G.3
McKenzie, A.N.J.4
Donaldson, D.D.5
Dekruyff, R.H.6
Umetsu, D.T.7
-
4
-
-
0142219240
-
Targeted Inactivation of the IL-4 Receptor alpha Chain I4R Motif Promotes Allergic Airway Inflammation
-
DOI 10.1084/jem.20030471
-
Blaeser, F., P. J. Bryce, N. Ho, V. Raman, F. Dedeoglu, D. D. Donaldson, R. S. Geha, H. C. Oettgen, and T. A. Chatila. 2003. Targeted inactivation of the IL-4 receptor alpha chain I4R motif promotes allergic airway inflammation. J. Exp. Med. 198: 1189-1200. (Pubitemid 37323384)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.8
, pp. 1189-1200
-
-
Blaeser, F.1
Bryce, P.J.2
Ho, N.3
Raman, V.4
Dedeoglu, F.5
Donaldson, D.D.6
Geha, R.S.7
Oettgen, H.C.8
Chatila, T.A.9
-
5
-
-
34249821341
-
Eosinophil trafficking in allergy and asthma
-
quiz 1311-1312
-
Rosenberg, H. F., S. Phipps, and P. S. Foster. 2007. Eosinophil trafficking in allergy and asthma. J. Allergy Clin. Immunol. 119: 1303-1310; quiz 1311-1312.
-
(2007)
J. Allergy Clin. Immunol.
, vol.119
, pp. 1303-1310
-
-
Rosenberg, H.F.1
Phipps, S.2
Foster, P.S.3
-
6
-
-
63449132488
-
Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in themouse lung
-
Lewis, C. C., B. Aronow, J. Hutton, J. Santeliz, K. Dienger, N. Herman, F. D. Finkelman, and M. Wills-Karp. 2009. Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in themouse lung. J. Allergy Clin. Immunol. 123: 795-804.e8.
-
(2009)
J. Allergy Clin. Immunol.
, vol.123
-
-
Lewis, C.C.1
Aronow, B.2
Hutton, J.3
Santeliz, J.4
Dienger, K.5
Herman, N.6
Finkelman, F.D.7
Wills-Karp, M.8
-
7
-
-
26844435631
-
The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia
-
Pope, S. M., N. Zimmermann, K. F. Stringer, M. L. Karow, and M. E. Rothenberg. 2005. The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia. J. Immunol. 175: 5341-5350. (Pubitemid 41456420)
-
(2005)
Journal of Immunology
, vol.175
, Issue.8
, pp. 5341-5350
-
-
Pope, S.M.1
Zimmermann, N.2
Stringer, K.F.3
Karow, M.L.4
Rothenberg, M.E.5
-
8
-
-
34250159031
-
Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma
-
Ochkur, S. I., E. A. Jacobsen, C. A. Protheroe, T. L. Biechele, R. S. Pero, M. P. McGarry, H. Wang, K. R. O'Neill, D. C. Colbert, T. V. Colby, et al. 2007. Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma. J. Immunol. 178: 7879-7889. (Pubitemid 46898060)
-
(2007)
Journal of Immunology
, vol.178
, Issue.12
, pp. 7879-7889
-
-
Ochkur, S.I.1
Jacobsen, E.A.2
Protheroe, C.A.3
Biechele, T.L.4
Pero, R.S.5
McGarry, M.P.6
Wang, H.7
O'Neill, K.R.8
Colbert, D.C.9
Colby, T.V.10
Shen, H.11
Blackburn, M.R.12
Irvin, C.C.13
Lee, J.J.14
Lee, N.A.15
-
9
-
-
66249142299
-
Expression of survivin in lung eosinophils is associated with pathology in a mouse model of allergic asthma
-
Tumes, D. J., A. Connolly, and L. A. Dent. 2009. Expression of survivin in lung eosinophils is associated with pathology in a mouse model of allergic asthma. Int. Immunol. 21: 633-644.
-
(2009)
Int. Immunol.
, vol.21
, pp. 633-644
-
-
Tumes, D.J.1
Connolly, A.2
Dent, L.A.3
-
10
-
-
0034669921
-
Murine eotaxin-2: A constitutive eosinophil chemokine induced by allergen challenge and IL-4 overexpression
-
Zimmermann, N., S. P. Hogan, A. Mishra, E. B. Brandt, T. R. Bodette, S. M. Pope, F. D. Finkelman, and M. E. Rothenberg. 2000. Murine eotaxin-2: a constitutive eosinophil chemokine induced by allergen challenge and IL-4 overexpression. J. Immunol. 165: 5839-5846.
-
(2000)
J. Immunol.
, vol.165
, pp. 5839-5846
-
-
Zimmermann, N.1
Hogan, S.P.2
Mishra, A.3
Brandt, E.B.4
Bodette, T.R.5
Pope, S.M.6
Finkelman, F.D.7
Rothenberg, M.E.8
-
11
-
-
13944249962
-
Mast cells in the development of adaptive immune responses
-
DOI 10.1038/ni1158
-
Galli, S. J., S. Nakae, and M. Tsai. 2005. Mast cells in the development of adaptive immune responses. Nat. Immunol. 6: 135-142. (Pubitemid 40268194)
-
(2005)
Nature Immunology
, vol.6
, Issue.2
, pp. 135-142
-
-
Galli, S.J.1
Nakae, S.2
Tsai, M.3
-
12
-
-
4344698420
-
Histamine-cytokine connection in immunity and hematopoiesis
-
DOI 10.1016/j.cytogfr.2004.06.003, PII S1359610104000577
-
Dy, M., and E. Schneider. 2004. Histamine-cytokine connection in immunity and hematopoiesis. Cytokine Growth Factor Rev. 15: 393-410. (Pubitemid 39140701)
-
(2004)
Cytokine and Growth Factor Reviews
, vol.15
, Issue.5
, pp. 393-410
-
-
Dy, M.1
Schneider, E.2
-
13
-
-
33646857548
-
+ T cells
-
Dunford, P. J., N. O'Donnell, J. P. Riley, K. N. Williams, L. Karlsson, and R. L. Thurmond. 2006. The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells. J. Immunol. 176: 7062-7070. (Pubitemid 43787887)
-
(2006)
Journal of Immunology
, vol.176
, Issue.11
, pp. 7062-7070
-
-
Dunford, P.J.1
O'Donnell, N.2
Riley, J.P.3
Williams, K.N.4
Karlsson, L.5
Thurmond, R.L.6
-
14
-
-
33745192634
-
The H1 histamine receptor regulates allergic lung responses
-
Bryce, P. J., C. B. Mathias, K. L. Harrison, T. Watanabe, R. S. Geha, and H. C. Oettgen. 2006. The H1 histamine receptor regulates allergic lung responses. J. Clin. Invest. 116: 1624-1632.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1624-1632
-
-
Bryce, P.J.1
Mathias, C.B.2
Harrison, K.L.3
Watanabe, T.4
Geha, R.S.5
Oettgen, H.C.6
-
15
-
-
0035958707
-
Mice lacking histidine decarboxylase exhibit abnormal mast cells
-
DOI 10.1016/S0014-5793(01)02663-1, PII S0014579301026631
-
Ohtsu, H., S. Tanaka, T. Terui, Y. Hori, Y. Makabe-Kobayashi, G. Pejler, E. Tchougounova, L. Hellman, M. Gertsenstein, N. Hirasawa, et al. 2001. Mice lacking histidine decarboxylase exhibit abnormal mast cells. FEBS Lett. 502: 53-56. (Pubitemid 32722059)
-
(2001)
FEBS Letters
, vol.502
, Issue.1-2
, pp. 53-56
-
-
Ohtsu, H.1
Tanaka, S.2
Terui, T.3
Hori, Y.4
Makabe-Kobayashi, Y.5
Pejler, G.6
Tchougounova, E.7
Hellman, L.8
Gertsenstein, M.9
Hirasawa, N.10
Sakurai, E.11
Buzas, E.12
Kovacs, P.13
Csaba, G.14
Kittel, A.15
Okada, M.16
Hara, M.17
Mar, L.18
Numayama-Tsuruta, K.19
Ishigaki-Suzuki, S.20
Ohuchi, K.21
Ichikawa, A.22
Falus, A.23
Watanabe, T.24
Nagy, A.25
more..
-
16
-
-
0033918507
-
Abnormal functional and morphological regulation of the gastric mucosa in histamine H2 receptor-deficient mice
-
Kobayashi, T., S. Tonai, Y. Ishihara, R. Koga, S. Okabe, and T. Watanabe. 2000. Abnormal functional and morphological regulation of the gastric mucosa in histamine H2 receptor-deficient mice. J. Clin. Invest. 105: 1741-1749. (Pubitemid 30421755)
-
(2000)
Journal of Clinical Investigation
, vol.105
, Issue.12
, pp. 1741-1749
-
-
Kobayashi, T.1
Tonai, S.2
Ishihara, Y.3
Koga, R.4
Okabe, S.5
Watanabe, T.6
-
18
-
-
0038337164
-
Desloratadine inhibits allergen-induced airway inflammation and bronchial hyperresponsiveness and alters T-cell responses in murine models of asthma
-
DOI 10.1067/mai.2003.1616
-
Bryce, P. J., R. Geha, and H. C. Oettgen. 2003. Desloratadine inhibits allergen-induced airway inflammation and bronchial hyperresponsiveness and alters T-cell responses in murine models of asthma. J. Allergy Clin. Immunol. 112: 149-158. (Pubitemid 36819820)
-
(2003)
Journal of Allergy and Clinical Immunology
, vol.112
, Issue.1
, pp. 149-158
-
-
Bryce, P.J.1
Geha, R.2
Oettgen, H.C.3
-
19
-
-
0036978843
-
4 receptor on human eosinophils - Role in eosinophil chemotaxis
-
DOI 10.1081/RRS-120014612
-
O'Reilly, M., R. Alpert, S. Jenkinson, R. P. Gladue, S. Foo, S. Trim, B. Peter, M. Trevethick, and M. Fidock. 2002. Identification of a histamine H4 receptor on human eosinophils: role in eosinophil chemotaxis. J. Recept. Signal Transduct. Res. 22: 431-448. (Pubitemid 36169163)
-
(2002)
Journal of Receptors and Signal Transduction
, vol.22
, Issue.1-4
, pp. 431-448
-
-
O'Reilly, M.1
Alpert, R.2
Jenkinson, S.3
Gladue, R.P.4
Foo, S.5
Trim, S.6
Peter, B.7
Trevethick, M.8
Fidock, M.9
-
20
-
-
4143075735
-
Interactions between eotaxin, histamine and mast cells in early microvascular events associated with eosinophil recruitment to the site of allergic skin reactions in humans
-
DOI 10.1111/j.1365-2222.2004.02014.x
-
Menzies-Gow, A., S. Ying, S. Phipps, and A. B. Kay. 2004. Interactions between eotaxin, histamine and mast cells in early microvascular events associated with eosinophil recruitment to the site of allergic skin reactions in humans. Clin. Exp. Allergy 34: 1276-1282. (Pubitemid 39093069)
-
(2004)
Clinical and Experimental Allergy
, vol.34
, Issue.8
, pp. 1276-1282
-
-
Menzies-Gow, A.1
Ying, S.2
Phipps, S.3
Kay, A.B.4
-
21
-
-
0036721776
-
Eotaxin (CCL11) and eotaxin-2 (CCL24) induce recruitment of eosinophils, basophils, neutrophils, and macrophages as well as features of early- and late-phase allergic reactions following cutaneous injection in human atopic and nonatopic volunteers
-
Menzies-Gow, A., S. Ying, I. Sabroe, V. L. Stubbs, D. Soler, T. J. Williams, and A. B. Kay. 2002. Eotaxin (CCL11) and eotaxin-2 (CCL24) induce recruitment of eosinophils, basophils, neutrophils, and macrophages as well as features of early- and late-phase allergic reactions following cutaneous injection in human atopic and nonatopic volunteers. J. Immunol. 169: 2712-2718. (Pubitemid 34921020)
-
(2002)
Journal of Immunology
, vol.169
, Issue.5
, pp. 2712-2718
-
-
Menzies-Gow, A.1
Ying, S.2
Sabroe, I.3
Stubbs, V.L.4
Soler, D.5
Williams, T.J.6
Kay, A.B.7
-
22
-
-
3242798754
-
Liver-expressed chemokine/CC chemokine ligand 16 attracts eosinophils by interacting with histamine H4 receptor
-
Nakayama, T., Y. Kato, K. Hieshima, D. Nagakubo, Y. Kunori, T. Fujisawa, and O. Yoshie. 2004. Liver-expressed chemokine/CC chemokine ligand 16 attracts eosinophils by interacting with histamine H4 receptor. J. Immunol. 173: 2078-2083. (Pubitemid 38971645)
-
(2004)
Journal of Immunology
, vol.173
, Issue.3
, pp. 2078-2083
-
-
Nakayama, T.1
Kato, Y.2
Hieshima, K.3
Nagakubo, D.4
Kunori, Y.5
Fujisawa, T.6
Yoshie, O.7
-
23
-
-
33646431450
-
Histamine receptors in immune regulation and allergen-specific immunotherapy
-
Jutel, M., K. Blaser, and C. A. Akdis. 2006. Histamine receptors in immune regulation and allergen-specific immunotherapy. Immunol. Allergy Clin. North Am. 26: 245-259, vii.
-
(2006)
Immunol. Allergy Clin. North Am.
, vol.26
-
-
Jutel, M.1
Blaser, K.2
Akdis, C.A.3
-
24
-
-
79955740934
-
Selective stimulation of IL-4 receptor on smooth muscle induces airway hyperresponsiveness in mice
-
Perkins, C., N. Yanase, G. Smulian, L. Gildea, T. Orekov, C. Potter, F. Brombacher, B. Aronow, M. Wills-Karp, and F. D. Finkelman. 2011. Selective stimulation of IL-4 receptor on smooth muscle induces airway hyperresponsiveness in mice. J. Exp. Med. 208: 853-867.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 853-867
-
-
Perkins, C.1
Yanase, N.2
Smulian, G.3
Gildea, L.4
Orekov, T.5
Potter, C.6
Brombacher, F.7
Aronow, B.8
Wills-Karp, M.9
Finkelman, F.D.10
-
25
-
-
13844274981
-
Cytokine-stimulated human lung alveolar epithelial cells release eotaxin-2 (CCL24) and eotaxin-3 (CCL26)
-
Heiman, A. S., B. O. Abonyo, S. F. Darling-Reed, and M. S. Alexander. 2005. Cytokine-stimulated human lung alveolar epithelial cells release eotaxin-2 (CCL24) and eotaxin-3 (CCL26). J. Interferon Cytokine Res. 25: 82-91. (Pubitemid 40250350)
-
(2005)
Journal of Interferon and Cytokine Research
, vol.25
, Issue.2
, pp. 82-91
-
-
Heiman, A.S.1
Abonyo, B.O.2
Darling-Reed, S.F.3
Alexander, M.S.4
-
26
-
-
77951672627
-
Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma
-
Dougherty, R. H., S. S. Sidhu, K. Raman, M. Solon, O. D. Solberg, G. H. Caughey, P. G. Woodruff, and J. V. Fahy. 2010. Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma. J. Allergy Clin. Immunol. 125: 1046-1053.e8.
-
(2010)
J. Allergy Clin. Immunol.
, vol.125
-
-
Dougherty, R.H.1
Sidhu, S.S.2
Raman, K.3
Solon, M.4
Solberg, O.D.5
Caughey, G.H.6
Woodruff, P.G.7
Fahy, J.V.8
-
27
-
-
0030772640
-
International union of pharmacology. XIII. Classification of histamine receptors
-
Hill, S. J., C. R. Ganellin, H. Timmerman, J. C. Schwartz, N. P. Shankley, J. M. Young, W. Schunack, R. Levi, and H. L. Haas. 1997. International Union of Pharmacology. XIII. Classification of histamine receptors. Pharmacol. Rev. 49: 253-278. (Pubitemid 27414915)
-
(1997)
Pharmacological Reviews
, vol.49
, Issue.3
, pp. 253-278
-
-
Hill, S.J.1
Ganellin, C.R.2
Timmerman, H.3
Schwartz, J.C.4
Shankley, N.P.5
Young, J.M.6
Schunack, W.7
Levi, R.8
Haas, H.L.9
-
28
-
-
0029948346
-
2 receptors
-
DOI 10.1073/pnas.93.13.6802
-
Smit, M. J., R. Leurs, A. E. Alewijnse, J. Blauw, G. P. Van Nieuw Amerongen, Y. Van De Vrede, E. Roovers, and H. Timmerman. 1996. Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors. Proc. Natl. Acad. Sci. USA 93: 6802-6807. (Pubitemid 26230391)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.13
, pp. 6802-6807
-
-
Smit, M.J.1
Leurs, R.2
Alewijnse, A.E.3
Blauw, J.4
Van Nieuw, A.G.P.5
Van De, V.Y.6
Roovers, E.7
Timmerman, H.8
-
29
-
-
36049045011
-
1 is required for TCR-mediated p38 MAPK activation and optimal IFN-gamma production in mice
-
DOI 10.1172/JCI32792
-
Noubade, R., G. Milligan, J. F. Zachary, E. P. Blankenhorn, R. del Rio, M. Rincon, and C. Teuscher. 2007. Histamine receptor H1 is required for TCR-mediated p38 MAPK activation and optimal IFN-gamma production in mice. J. Clin. Invest. 117: 3507-3518. (Pubitemid 350097006)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.11
, pp. 3507-3518
-
-
Noubade, R.1
Milligan, G.2
Zachary, J.F.3
Blankenhorn, E.P.4
Del, R.R.5
Rincon, M.6
Teuscher, C.7
-
30
-
-
0035959904
-
Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors
-
DOI 10.1038/35096564
-
Jutel, M., T. Watanabe, S. Klunker, M. Akdis, O. A. Thomet, J. Malolepszy, T. Zak-Nejmark, R. Koga, T. Kobayashi, K. Blaser, and C. A. Akdis. 2001. Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors. Nature 413: 420-425. (Pubitemid 32928596)
-
(2001)
Nature
, vol.413
, Issue.6854
, pp. 420-425
-
-
Jutel, M.1
Watanabe, T.2
Klunker, S.3
Akdis, M.4
Thomet, O.A.R.5
Malolepszy, J.6
Zak-Nejmark, T.7
Koga, R.8
Kobayashi, T.9
Blaser, K.10
Akdis, C.A.11
-
31
-
-
33750460981
-
IgE isotype switch and IgE production are enhanced in IL-21-deficient but not IFN-gamma-deficient mice in a Th2-biased response
-
DOI 10.1016/j.cellimm.2006.07.011, PII S0008874906001298
-
Shang, X. Z., K. Y. Ma, J. Radewonuk, J. Li, X. Y. Song, D. E. Griswold, E. Emmell, and L. Li. 2006. IgE isotype switch and IgE production are enhanced in IL-21-deficient but not IFN-gamma-deficient mice in a Th2-biased response. Cell. Immunol. 241: 66-74. (Pubitemid 44648023)
-
(2006)
Cellular Immunology
, vol.241
, Issue.2
, pp. 66-74
-
-
Shang, X.Z.1
Ma, K.Y.2
Radewonuk, J.3
Li, J.4
Song, X.Y.5
Griswold, D.E.6
Emmell, E.7
Li, L.8
-
32
-
-
0023785192
-
Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures
-
Lebman, D. A., and R. L. Coffman. 1988. Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures. J. Exp. Med. 168: 853-862.
-
(1988)
J. Exp. Med.
, vol.168
, pp. 853-862
-
-
Lebman, D.A.1
Coffman, R.L.2
-
33
-
-
15844374279
-
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene
-
DOI 10.1038/380630a0
-
Shimoda, K., J. van Deursen, M. Y. Sangster, S. R. Sarawar, R. T. Carson, R. A. Tripp, C. Chu, F. W. Quelle, T. Nosaka, D. A. Vignali, et al. 1996. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature 380: 630-633. (Pubitemid 26119016)
-
(1996)
Nature
, vol.380
, Issue.6575
, pp. 630-633
-
-
Shimoda, H.1
Van Deursen, J.2
Sangster, M.Y.3
Sarawar, S.R.4
Carson, R.T.5
Tripp, R.A.6
Chuo, C.7
Quelle, F.W.8
Nosaka, T.9
Vignali, D.A.A.10
Doherty, P.C.11
Grosveld, G.12
Paul, W.E.13
Ihle, J.N.14
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