Abnormal functional and morphological regulation of the gastric mucosa in histamine H2 receptor-deficient mice

Journal of Clinical Investigation

Volumn 105, Issue 12, 2000, Pages 1741-1749

  Kobayashi, Takashi ^a   Tonai, Shunsuke ^b   Ishihara, Yasunobu ^c   Koga, Ritsuko ^a   Okabe, Susumu ^b   Watanabe, Takeshi ^a,d  

^a KYUSHU UNIVERSITY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^c SHIONOGI AND CO LTD   (Japan)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBACHOL; GASTRIN; HISTAMINE; HISTAMINE H2 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; GENE TARGETING; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; STOMACH ACID SECRETION; STOMACH MUCOSA;

EID: 0033918507     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI9441     Document Type: Article

References (34)

1. Karam, S.M., and Leblond, C.P. 1992. Identifying and counting epithelial cell types in the "corpus" of the mouse stomach. Anat. Rec. 232:231-246.
2. Hersey, S.J., and Sachs, G. 1995. Gastric acid secretion. Physiol. Rev. 75:155-189.
3. Shamburek, R.D., and Schubert, M.L. 1993. Pharmacology of gastric acid inhibition. Baillieres Clin. Gastroenterol. 7:23-54
4. Feldman, M., and Burton, M.E. 1990. Histamine2-receptor antagonists. Standard therapy for acid-peptic diseases (1). N. Engl. J. Med. 323:1672-1680.
5. Feldman, M., and Burton, M.E. 1990. Histamine2-receptor antagonists. Standard therapy for acid-peptic diseases (2). N. Engl. J. Med 323:1749-1755.
6. Soll, A.H. 1978. The interaction of histamine with gastric and carbamylcholine on oxygen uptake by isolated mammalian parietal cells. J. Clin. Invest. 61:381-389.
7. Soll, A.H. 1982. Potentiating interactions of gastric stimulants on [14 C] aminopyrine accumulation by isolated canine parietal cells. Gastroenterology. 83:216-223.
8. Li, Z.Q., Cabero, J.L., and Mardh, S. 1995. Gastrin and carbachol require cAMP to elicit aminopyrine accumulation in isolated pig and rat parietal cells. Am. J. Physiol. 268:G82-G89.
9. +- and cAMP-dependent stimulatory pathways in parietal cells. Biochim. Biophys. Acta. 1311:133-142.
10. Karam, S.M. 1993. Dynamics of epithelial cells in the corpus of the mouse stomach. IV. Bidirectional migration of parietal cells ending in their gradual degeneration and loss. Anat. Rec. 236:314-332.
11. Courtois-Coutry, N., et al. 1997. A tyrosine-based signal targets H/K-ATPase to a regulated compartment and is required for the cessation of gastric acid secretion. Cell. 90:501-510.
12. +-adenosine triphosphatase β subunit is required for normal function, development, and membrane structure of mouse parietal cells. Gastroenterology. 117:605-618.
13. Jones, M.K., Tomikawa, M., Mohajet, B., and Tarnawski, A.S. 1999. Gastrointestinal mucosal regeneration: role of growth factors. Front. Biosci. 4:D303-D309.
14. Larsson, H., et al. 1986. Plasma gastrin and gastric enterochromaffinlike cell activation and proliferation. Studies with omeprazole and ranitidine in intact and antrectomized rats. Gastroenterology. 90:391-399.
15. Ryberg, B., Axelson, J., Hakanson, R., Sundler, F., and Mattsson, H. 1990. Trophic effects of continuous infusion of [Leu 15]-gastrin-17 in the rat. Gastroenterology. 98:33-38.
16. Lee, H., Hakanson, R., Karlsson, A., Mattsson, H., and Sundler, F. 1992. Lansoprazole and omeprazole have similar effects on plasma gastrin levels, enterochromaffin-like cells, gastrin cells and somatostatin cells in the rat stomach. Digestion. 51:125-132.
17. Nagata, A., et al. 1996. G protein-coupled cholecystokinin-B/gastrin receptors are responsible for physiological cell growth of the stomach mucosa in vivo. Proc. Natl. Acad. Sci. USA. 93: 11825-11830.
18. Koh, T.J., et al. 1997. Gastrin deficiency results in altered gastric differentiation and decreased colonic proliferation in mice. Gastroenterology. 113:1015-1025.
19. Langhans, N., et al. 1997. Abnormal gastric histology and decreased acid production in cholecystokinin-B/gastrin receptor-deficient mice. Gastroenterology. 112:280-286.
20. Früs-Hansen, L., et al. 1998. Impaired gastric acid secretion in gastrin-deficient mice. Am. J. Physiol. 274:G561-G568.
21. Ciacci, C., et al. 1996. Histamine H2-receptor antagonists stimulate proliferation but not migration of human gastric mucosal cells in vitro. Dig. Dis. Sci. 41:972-978.
22. Kobayashi, T., et al. 1996. Cloning, RNA expression, and chromosomal location of a mouse histamine H2 receptor gene. Genomics. 37:390-394.
23. Wang, T.C., et al. 1996. Processing and proliferative effects of human progastrin in transgenic mice. J. Clin. Invest. 98:1918-1929.
24. 14C]aminopyrine accumulation by isolated canine parietal cells. Am. J. Physiol. 238:G366-G375.
25. Soll, A.H., Amirian, D.A., Thomas, L.P., Reedy, T.J., and Elashoff, J.D. 1984. Gastrin receptors on isolated canine parietal cells. J. Clin. Invest. 73:1434-1447.
26. Black, J.W., Duncan, W.A., Durant, C.J., Ganellin, C.R., and Parsons, E.M. 1972. Definition and antagonism of histamine H 2-receptors. Nature. 236:385-390.
27. Grossman, M.I., and Konturek, S.J. 1974. Inhibition of acid secretion in dog by metiamide, a histamine antagonist acting on H2 receptors. Gastroenterology. 66:517-521.
28. Hirschowitz, B.I., and Molina, E. 1983. Effects of four H2 histamine antagonists on bethanechol-stimulated acid and pepsin secretion in the dog. J. Pharmacol. Exp. Ther. 224:341-345.
29. Kodaira, M., et al. 1999. Functional muscarinic m3 receptor expressed in gastric cancer cells stimulates tyrosine phosphorylation and MAP kinase. J. Gastroenterol. 34:163-171.
30. Arnold, R., Frank, M., Simon, B., Eissele, R., and Koop, H. 1992. Adaptation and renewal of the endocrine stomach. Scand. J. Gastroenterol. Suppl. 193:20-27.
31. Arnold, R., et al. 1982. Antral gastrin-producing G-cells and somatostatin-producing D-cells in different states of gastric acid secretion. Gut. 23:285-291.
32. Creutzfeldt, W., et al. 1986. Effect of short- and long-term feeding of omeprazole on rat gastric endocrine cells. Digestion. 35(Suppl. 1):84-97.
33. Ito, M., et al. 1993. Functional characterization of a human brain cholecystokinin-B receptor. A trophic effect of cholecystokinin and gastrin. J. Biol. Chem. 268:18300-18305.
34. Seva, C., Dickinson, C.J., and Yamada, T. 1994. Growth-promoting effects of glycine-extended progastrin. Science. 265:410-412.