Synergistic anticancer activity of curcumin and catechin: An in vitro study using human cancer cell lines

Microscopy Research and Technique

Volumn 75, Issue 2, 2012, Pages 112-116

  Manikandan, R ^a   Beulaja, M ^b   Arulvasu, C ^b   Sellamuthu, S ^b   Dinesh, D ^b   Prabhu, D ^b   Babu, G ^b   Vaseeharan, B ^a   Prabhu, N M ^a  

^a ALAGAPPA UNIVERSITY   (India)

^b UNIVERSITY OF MADRAS   (India)

Author keywords

Apoptosis; Catechin; Curcumin

Indexed keywords

CELL CULTURE; DISEASES; FLAVONOIDS; FOOD PRODUCTS; PLANTS (BOTANY); POLYPHENOLIC COMPOUNDS;

ANTI-CANCER AGENTS; ANTICANCER ACTIVITIES; CANCER CELL LINES; CARCINOGENESES; CATECHIN; CELL LINES; CURCUMIN; HUMAN CANCER CELLS; IN-VITRO; VITRO STUDIES;

CELL DEATH;

CAMELLIA SINENSIS; CURCUMA LONGA;

EID: 84855986278     PISSN: 1059910X     EISSN: 10970029     Source Type: Journal    
DOI: 10.1002/jemt.21032     Document Type: Article

References (31)

1. Aggarwal BB, Kumar A, Bharti AC. 2003. Anti-cancer potential of curcumin: Preclinical and clinical studies. Anti Res 23: 363-398.
2. Arulvasu C, Babu G, Manikandan R, Srinivasan P, Sellamuthu S, Prabhu D, Dinesh D. 2010. Anti-cancer effect of Datura innoxia P.mill. leaf extract in vitro through induction of apoptosis in human colon adenocarcinoma and larynx cancer cell lines. J Pharma Res 3: 1485-1488.
3. Babich H, Krupka ME, Nissim HA, Zuckerbraun HL. 2005. Differential in vitro cytotoxicity of (-)-epicatechin gallate (ECG) to cancer and normal cells from the human oral cavity. Toxicol In Vitro 19: 231-242.
4. Balachandran P, Govindarajan R. 2005. Cancer-an ayurvedic perspective. Pharmacol Res 51: 19-30.
5. Chainani-Wu N. 2003. Safety and anti-inflammatory activity of curcumin: A component of tumeric (Curcuma longa). J Altern Complement Med 9: 161-168.
6. Daniel S, Limson JL, Dairam A, Watkins GM, Daya S. 2004. Through metal binding, curcumin protects against lead- and cadmium-induced lipid peroxidation in rat brain homogenates and against lead-induced tissue damage in rat brain. J Inorg Biochem 98: 266-275.
7. Duvoix A, Blasius R, Delhalle S, Schnekenburger M, Morceau F, Henry E, Dicato M, Diederich M. 2005. Chemopreventive and therapeutic effects of curcumin. Cancer Lett 223: 181-190.
8. Graham HN. 1992. Green tea composition, consumption, and polyphenol chemistry. Prev Med 21: 334-350.
9. Higdon JV, Frei B. 2003. Tea catechins and polyphenols; health effects, metabolism and antioxidant functions. Crit Rev Food Sci Nutr 43: 89-143.
10. Ho YS, Wang YJ, Lin JK. 1996. Induction of p53 and p21/ WAF1/CIP1 expression by nitric oxide and their association with apoptosis in human cancer cells. Mol Carcinog 16: 20-31.
11. Katiyar SK, Mukhtar H. 1997. Tea antioxidants in cancer chemoprevention. J Cell Biochem suppl 27: 59-67.
12. Lee KH. 1999. Anti-cancer drug design based on plant-derived natural products. J Biomed Sci 6: 236-250.
13. p58- mediated apoptosis induced by cycloheximide. Biochem Biophys Res Comm 327: 628-636.
14. Lin JK, Liang YC. 2000. Cancer chemoprevention by tea polyphenols. Proc Natl Sci Counc Repub China B 4: 1-13.
15. Manikandan R, Thiagarajan R, Beulaja S, Sudhandiran G, Arumugam M. 2010. Curcumin prevents free radical-mediated cataractogenesis through modulations in lens calcium. Free Radic Biol Med 48: 483-492.
16. Masuda T, Hidaka K, Shinohara A, Maekawa T, Takeda Y, Yamaguchi H. 1999. Chemical studies on antioxidant mechanism of curcuminoid: Analysis of radical reaction products from curcumin. J Agric Food Chem 47: 71-77.
17. Moongkarndi P, Kosem N, Luanratana O, Jongsomboonkusol S, Pongpan N. 2004. Antiproliferative activity of Thai medicinal plant extracts on human breast adenocarcinoma cell line. Fitoterapia 75: 375-377.
18. Mukhtar H, Ahmad N. 2000. Tea polyphenols: Prevention of cancer and optimizing health. Am J Clin Nutr 71: 1698-1702.
19. Pezzuto JM. 1997. Plant-derived anti-cancer agents. Biochem Pharmacol 24: 121-133.
20. Qanungo S, Das M, Haldar S, Basu A. 2005. Epigallocatechin-3-gallate induces mitochondrial membrane depolarization and caspase-dependent apoptosis in pancreatic cancer cells. Carcinogenesis 26: 958-967.
21. Salah N, Miller NJ, Paganga G, Tijburg L, Bolwell GP, Rice-Evans C. 1995. Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants. Arch Biochem Biophys 322: 339-346.
22. Santel T, Pflug G, Hemdan NY, Schafer A, Hollenbach M, Buchold M.Hintersdorf A, Lindner IOtto A, Bigl M, Oerlecke I, Hutschenreuter A, Sack U, Huse K, Groth M, Birkemeyer C, Schellenberger W, Gebhardt R, Platzer M, Weiss T, Vijayalakshmi MA, Kruger M, Birkenmeier G. 2008. Curcumin inhibits glyoxalase 1: A possible link to its anti-inflammatory and anti-tumor activity. PLos One 3: 3508.
23. Shishodia S, Sethi G, Aggarwal BB. 2005. Curcumin: Getting back to the roots. Ann N Y Acad Sci 1056: 206-117.
24. Singh DK, Lippman SM. 1998. Cancer chemoprevention, part 1: Retenoids and carotenoids and other classic antioxidants. Oncology 12: 1643-1660.
25. Song SL, Kuang CL, Shu CH, Jai SY, Chao LK, Jing PL, Yi SM, Chih CW, Jing GC. 2009. Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and-9 and vascular endothelial growth factor (VEGF). Cancer Lett 285: 127-133.
26. Su CC, Chen GW, Lin JG, Wu LT, Chung JG. 2006. Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions. Anticancer Res 26: 1281-1288.
27. Surh YJ. 2003. Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 3: 768-780.
28. Thayyullathil F, Chathoth S, Hago A, Patel M, Galadari S. 2008. Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and -independent apoptosis in L929 cells. Free Radic Biol Med 45: 1403-1412.
29. Tomita M, Holman BJ, Santoro CP, Santoro TJ. 2005. Astrocyte production of the chemokine macrophage inflammatory protein-2 is inhibited by the spice principle curcumin at the level of gene transcription. J Neuroinflammation 2: 8.
30. Trevisanato SI, Kim YI. 2000. Tea and health. Nutr Rev 58: 1-10.
31. Yang CS, Landau JM, Huang MT, Newmark HL. 2001. Inhibition of carcinogenesis by dietary polyphenolic compounds. Ann Rev Nutr 21: 381-406.