Molecular and cell signaling targets for PTSD pathophysiology and pharmacotherapy

Neuropharmacology

Volumn 62, Issue 2, 2012, Pages 705-714

  Hauger, Richard L ^a,b   Olivares Reyes, J Alberto ^c   Dautzenberg, Frank M ^d   Lohr, James B ^a,b   Braun, Sandra ^b   Oakley, Robert H ^e  

^a VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c DEPARTAMENTO DE FÍSICA   (Mexico)

^d Nycomed GmbH   (Germany)

^e NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

arrestin; Biased agonist; CRF receptor; GRK

Indexed keywords

BETA ARRESTIN 2; BRAIN PROTEIN; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE 3; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P11; UNCLASSIFIED DRUG;

ANXIETY; BINDING AFFINITY; CELLULAR STRESS RESPONSE; CELLULAR STRESS SIGNAL; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 GENE; DEPRESSION; ENDOPHENOTYPE; ENZYME PHOSPHORYLATION; FKBP5 GENE; GENE; GENE EXPRESSION REGULATION; GENE EXPRESSION SYSTEM; GENETIC LINKAGE; HUMAN; MEMORY CONSOLIDATION; MOLECULAR PATHOLOGY; NONHUMAN; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; REVIEW; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; STAT5B GENE;

HUMANS; PHOSPHORYLATION; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; RECEPTORS, GLUCOCORTICOID; SIGNAL TRANSDUCTION; STRESS DISORDERS, POST-TRAUMATIC;

EID: 84855979157     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.11.007     Document Type: Review

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