Posttraumatic stress disorder: A state-of-the-science review

Journal of Psychiatric Research

Volumn 40, Issue 1, 2006, Pages 1-21

  Nemeroff, Charles B ^a   Bremner, J Douglas ^a   Foa, Edna B ^b   Mayberg, Helen S ^a   North, Carol S ^c   Stein, Murray B ^d  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antidepressants; Cognitive therapy; Early life trauma; Hippocampus; Posttraumatic stress disorder; Risk factors

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; PAROXETINE;

AGORAPHOBIA; ANXIETY DISORDER; BEHAVIOR; BRAIN FUNCTION; COGNITION; COMORBIDITY; DEPRESSION; EMOTIONAL STRESS; HEREDITY; HIPPOCAMPUS; HUMAN; MEMORY; PANIC; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; REVIEW; SEX DIFFERENCE; SEXUAL BEHAVIOR;

ADAPTATION, PSYCHOLOGICAL; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; ANXIETY DISORDERS; COGNITIVE THERAPY; COMORBIDITY; CROSS-SECTIONAL STUDIES; DEPRESSIVE DISORDER; HIPPOCAMPUS; HUMANS; LIFE CHANGE EVENTS; PAROXETINE; RISK FACTORS; STRESS DISORDERS, POST-TRAUMATIC;

EID: 30944454430     PISSN: 00223956     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2005.07.005     Document Type: Review

References (141)

1. American Psychiatric Association, Committee on Nomenclature and Statistics. Diagnostic and Statistical Manual of Mental Disorders. 3rd ed. Washington (DC): American Psychiatric Association; 1980.
2. B. Andrews, C.R. Brewin, and S. Rose Gender, social support, and PTSD in victims of violent crime J Trauma Stress 16 2003 421 427
3. Associated Press. Poll: Americans depressed, sleepless. Associated Press. 9/19/2001.Washington DC, Associated Press. Available from: www.chron.com/cs/ CDA/story.hts/special/terror/impact/1055126.
4. D.G. Baker, S.A. West, and W.E. Nicholson Serial CSF corticotropin- releasing hormone levels and adrenocortical activity in combat veterans with posttraumatic stress disorder Am J Psychiatry 156 1999 585 588
5. C.M. Banki, G. Bissette, and M. Arato CSF corticotropin-releasing factor-like immunoreactivity in depression and schizophrenia Am J Psychiatry 144 1987 873 877
6. H. Barbas, S. Saha, N. Rempel-Clower, and T. Ghashghaei Seial pathways from preimate prefrontal cortex to autonomic areas may influence emotional expression BMC Neurosci 4 2003 25
7. C.S. Barr, T.K. Newman, and M. Schwandt Sexual dichotomy of an interaction between early adversity and the serotonin transporter gene promoter variant in rhesus macaques Proc Natl Acad Sci USA 101 2004 12358 12363
8. J. Beals, S.M. Manson, and J.H. Shore The prevalence of posttraumatic stress disorder among American Indian Vietnam veterans: disparities and context J Trauma Stress 15 2002 89 97
9. J.A. Bennice, P.A. Resick, M. Mechanic, and M. Astin The relative effects of intimate partner physical and sexual violence on post-traumatic stress disorder symptomatology Violence Vict 18 2003 87 94
10. K.L. Bleiberg, and J.C. Markowitz A pilot study of interpersonal psychotherapy for posttraumatic stress disorder Am J Psychiatry 162 2005 181 183
11. O. Bonne, D. Brandes, and A. Gilboa Longitudinal MRI study of hippocampal volume in trauma survivors with PTSD Am J Psychiatry 158 2001 1248 1251
12. K. Brady, T. Pearlstein, and G.M. Asnis Efficacy and safety of sertraline treatment of posttraumatic stress disorder: a randomized controlled trial JAMA 283 2000 1837 1844
13. J.D. Bremner Neuroimaging of posttraumatic stress disorder Psychiatric Ann 28 1998 445 450
14. J.D. Bremner Does stress damage the brain? Understanding trauma-related disorders from a mind-body perspective 2002 W.W. Norton New York
15. J.D. Bremner, J. Licinio, and A. Darnell Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder Am J Psychiatry 154 1997 624 629
16. J.D. Bremner, M. Narayan, and L.H. Staib Neural correlates of memories of childhood sexual abuse in women with and without posttraumatic stress disorder Am J Psychiatry 156 1999 1787 1795
17. J.D. Bremner, P. Randall, and T.M. Scott Deficits in short-term memory in adult survivors of childhood abuse Psychiatry Res 59 1995 97 107
18. J.D. Bremner, P.R. Randall, and E. Vermetten MRI-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse: a preliminary report Biol Psychiatry 41 1997 23 32
19. J.D. Bremner, T.M. Scott, and R.C. Delaney Deficits in short-term memory in posttraumatic stress disorder Am J Psychiatry 150 1993 1015 1019
20. J.D. Bremner, P. Randall, and T.M. Scott MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder Am J Psychiatry 152 1995 973 981
21. J.D. Bremner, S.M. Southwick, D.R. Johnson, R. Yehuda, and D.S. Charney Childhood physical abuse and combat-related posttraumatic stress disorder in Vietnam veterans Am J Psychiatry 150 1993 235 239
22. J.D. Bremner, L.H. Staib, and D. Kaloupek Neural correlates of exposure to traumatic pictures and sound in Vietnam combat veterans with and without posttraumatic stress disorder: a positron emission tomography study Biol Psychiatry 45 1999 806 816
23. J.D. Bremner, M. Vythilingam, and E. Vermetten MRI and PET study of deficits in hippocampal structure and function in women with childhood sexual abuse and posttraumatic stress disorder Am J Psychiatry 160 2003 924 932
24. N. Breslau, and G.C. Davis Posttraumatic stress disorder in an urban population of young adults: risk factors for chronicity Am J Psychiatry 149 1992 671 675
25. N. Breslau, G.C. Davis, and P. Andreski Sex differences in posttraumatic stress disorder Arch Gen Psychiatry 54 1997 1044 1048
26. R.A. Bryant, M.L. Moulds, and R.M. Guthrie Imaginal exposure alone and imaginal exposure with cognitive restructuring in treatment of posttraumatic stress disorder J Consulting Clin Psychol 71 2003 706 712
27. Cahill SP, Foa EB, Rothbaum BO, Connor K, Smith R, Davidson JRT. Augmentation of sertraline with prolonged exposure (PE) in the treatment of PTSD: does PE protect against relapse? In: Poster presented at the annual convention of the anxiety disorders association of America, Toronto, Ontario, Canada, March 2003.
28. A and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat Neuropsychopharmacology 22 2000 219 229
29. J.J. Card Epidemiology of PTSD in a national cohort of Vietnam veterans J Clin Psychol 43 1987 6 17
30. L.L. Carpenter, A.R. Tyrka, and C.J. McDougle Cerebrospinal fluid corticotropin-releasing factor and perceived early-life stress in depressed patients and healthy control subjects Neuropsychopharmacology 29 2004 777 784
31. V.G. Carrion, C.F. Weems, and S. Eliez Attenuation of frontal asymmetry in pediatric posttraumatic stress disorder Biol Psychiatry 50 2001 943 951
32. A. Caspi, K. Sugden, and T.E. Moffitt Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene Science 301 2003 386 389
33. B. Chen, D. Dowlatshahi, G.M. MacQueen, J.F. Wang, and L.T. Young Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication Biol Psychiatry 50 2001 260 265
34. J.D. Coplan, M.W. Andrews, and L.A. Rosenblum Persistent elevations of cerebrospinal fluid concentrations of corticotropin-releasing factor in adult nonhuman primates exposed to early-life stressors: implications for the pathophysiology of mood and anxiety disorders Proc Natl Acad Sci USA 93 1996 1619 1623
35. P.R. Davidson, and K.C. Parker Eye movement desensitization and reprocessing (EMDR): a meta-analysis J Consult Clin Psychol 69 2001 305 316
36. M.D. De Bellis, J. Hall, A.M. Boring, K. Frustaci, and G. Moritz A pilot longitudinal study of hippocampal volumes in pediatric maltreatment-related posttraumatic stress disorder Biol Psychiatry 50 2001 305 309
37. M.D. De Bellis, M.S. Keshavan, and D.B. Clark A.E. Bennett Research Award: Developmental traumatology: Part II. Brain development Biol Psychiatry 45 1999 1271 1284
38. L.E. DeLisi, A. Maurizio, and M. Yost A survey of New Yorkers after the Sept. 11, 2001, terrorist attacks Am J Psychiatry 160 2003 780 783
39. D.J. Dobie, D.R. Kivlahan, C. Maynard, K.R. Bush, T.M. Davis, and K.A. Bradley Posttraumatic stress disorder in female veterans: association with self-reported health problems and functional impairment Arch Intern Med 164 2004 394 400
40. S.R. Dube, R.F. Anda, and V.J. Felitti Childhood abuse, household dysfunction, and the risk of attempted suicide throughout the life span: findings from the Adverse Childhood Experiences Study JAMA 286 2001 3089 3096
41. R.S. Duman, J. Malberg, and J. Thome Neural plasticity to stress and antidepressant treatment Biol Psychiatry 19 1999 1181 1191
42. R.S. Duman, S. Nakagawa, and J. Malberg Regulation of adult neurogenesis by antidepressant treatment Neuropsychopharmacology 25 2001 836 844
43. V.J. Edwards, G.W. Holden, V.J. Felitti, and R.F. Anda Relationship between multiple forms of childhood maltreatment and adult mental health in community respondents: results from the adverse childhood experiences study Am J Psychiatry 160 2003 1453 1460
44. B.M. Elzinga, C.G. Schmahl, E. Vermetten, R. van Dyck, and J.D. Bremner Higher cortisol levels following exposure to traumatic reminders in abuse-related PTSD Neuropsychopharmacology 28 2003 1656 1665
45. C.C. Engel, A.L. Engel, S.J. Campbell, M.E. McFall, J. Russo, and W. Katon Posttraumatic stress disorder symptoms and precombat sexual and physical abuse in Desert Storm veterans J Nerv Ment Dis 181 1993 683 688
46. F.F. Flach Psychobiologic resilience, psychotherapy, and the creative process Compr Psychiatry 21 1980 510 518
47. Foa EB, Hembree EA, Cahill SP, Rauch SA, Riggs DS, Feeny NC, et al. Randomized trail of prolonged exposure for PTSD with and without cognitive restructuring: Outcome at academic and community clinics. J Consult Clin Psychol (in press).
48. E.B. Foa, and L.H. Jaycox Cognitive-behavioral theory and treatment of post-traumatic stress disorder D.S. Spiegel Efficacy and cost-effectiveness of psychotherapy 1999 American Psychiatric Press Washington (DC) 23 61
49. E.B. Foa, and B.O. Rothbaum Treating the trauma of rape 1998 Guilford Press New York (NY)
50. E.B. Foa, C.V. Dancu, E.A. Hembree, L.H. Jaycox, E.A. Meadows, and G.P. Street A comparison of exposure therapy, stress inoculation training, and their combination for reducing posttraumatic stress disorder in female assault victims J Consult Clin Psychol 67 1999 194 200
51. E.B. Foa, A. Ehlers, D. Clark, D.F. Tolin, and S.M. Orsillo Posttraumatic Cognitions Inventory (PTCI): development and validation Psychol Assess 11 1999 303 314
52. E.B. Foa T.M. Keane M.J. Friedman Effective treatments for PTSD: practice guidelines from the International Society for Traumatic Stress Studies 2000 Guilford Press New York
53. E.B. Foa, B.O. Rothbaum, D.S. Riggs, and T.B. Murdock Treatment of posttraumatic stress disorder in rape victims: a comparison between cognitive-behavioral procedures and counseling J Consult Clin Psychol 59 1991 715 723
54. O. Frans, P.A. Rimmo, L. Aberg, and M. Fredrikson Trauma exposure and post-traumatic stress disorder in the general population Acta Psychiatr Scand 111 2005 291 299
55. L.J. Freedman, T.R. Insel, and Y. Smith Subcortical projections of area 25 (subgenual cortex) of the macaque monkey J Comp Neurol 421 2000 172 188
56. T.W. Freeman, D. Cardwell, C.N. Karson, and R.A. Komoroski In vivo proton magnetic resonance spectroscopy of the medial temporal lobes of subjects with combat-related posttraumatic stress disorder Magn Reson Med 40 1998 66 71
57. S. Galea, J. Ahern, and H. Resnick Psychological sequelae of the September 11 terrorist attacks in New York City New Engl J Med 346 2002 982 987
58. M.W. Gilbertson, M.E. Shenton, and A. Ciszewski Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma Nature Neurosci 5 2002 1242 1247
59. K. Goldapple, Z. Segal, and C. Garson Modulation of cortical-limbic pathways in major depression: treatment specific effects of cognitive behavioral therapy Arch Gen Psychiatry 61 2004 34 41
60. K. Goldapple, Z. Segal, and C. Garson Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy Arch Gen Psychiatry 61 2004 34 41
61. E. Gould, P. Tanapat, B.S. McEwen, G. Flugge, and E. Fuchs Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress Proc Natl Acad Sci USA 95 1998 3168 3171
62. T.G. Gurvits, M.R. Shenton, and H. Hokama Magnetic resonance imaging study of hippocampal volume in chronic combat-related posttraumatic stress disorder Biol Psychiatry 40 1996 192 199
63. C. Heim, D.J. Newport, and S. Heit Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood JAMA 284 2000 592 597
64. C. Heim, P.M. Plotsky, and C.B. Nemeroff Importance of studying the contributions of early adverse experience to neurobiological findings in depression Neuropsychopharmacology 29 2004 641 648
65. T.L. Holbrook, D.B. Hoyt, M.B. Stein, and W.J. Sieber Gender differences in long-term posttraumatic stress disorder outcomes after major trauma: women are at higher risk of adverse outcomes than men J Trauma 53 2002 882 888
66. R.L. Huot, P.M. Plotsky, R.H. Lenox, and R.K. McNamara Neonatal maternal separation reduces hippocampal mossy fiber density in adult Long Evans rats Brain Res 950 2002 52 63
67. R.L. Huot, K.V. Thrivikraman, M.J. Meaney, and P.M. Plotsky Development of adult ethanol preference and anxiety as a consequence of neonatal maternal separation in Long Evans rats and reversal with antidepressant treatment Psychopharmacology (Berl) 158 2001 366 373
68. H. Kang, N. Dalager, C. Mahan, and E. Ishii The role of sexual assault on the risk of PTSD among Gulf War veterans Ann Epidemiol 15 2005 191 195
69. T.M. Keane, J.A. Fairbank, and J.M. Caddell Implosive (flooding) therapy reduces symptoms of PTSD in Vietnam combat veterans Behav Ther 20 1989 245 260
70. M.L. Keightley, D.A. Seminowicz, and R.M. Bagby Personality influences limbic-cortical interactions during sad mood induction Neuroimage 20 2003 2031 2039
71. M.B. Keller, J.P. McCullough, and D.N. Klein A comparison of nefazodone, the cognitive-behavioral-analysis system of psychotherapy, and their combination for the treatment of chronic depression N Engl J Med 342 2000 1462 1470
72. K.S. Kendler, J. Kuhn, and C.A. Prescott The interrelationship of neuroticism, sex, and stressful life events in the prediction of episodes of major depression Am J Psychiatry 161 2004 631 636
73. S.H. Kennedy, K.R. Evans, and S. Kruger Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression Am J Psychiatry 158 2001 899 905
74. R.C. Kessler Posttraumatic stress disorder: the burden to the individual and to society J Clin Psychiatry 61 Suppl 5 2000 4 12 discussion: 13-4
75. R.C. Kessler, A. Sonnega, and E. Bromet Posttraumatic stress disorder in the National Comorbidity Survey Arch Gen Psychiatry 52 1995 1048 1060
76. S. Kruger, D. Seminowicz, and K. Goldapple State and trait influences on mood regulation in bipolar disorder: blood flow differences with an acute mood challenge Biol Psychiatry 54 2003 1274 1283
77. C.O. Ladd, M.J. Owens, and C.B. Nemeroff Persistent changes in corticotropin-releasing factor neuronal systems induced by maternal deprivation Endocrinology 137 1996 1212 1218
78. M. Liotti, H.S. Mayberg, S.K. Brannan, S. McGinnis, P. Jerabek, and P.T. Fox Differential limbic-cortical correlates of sadness and anxiety in healthy subjects: implications for affective disorder Biol Psychiatry 48 2000 30 42
79. M. Liotti, H.S. Mayberg, S. McGinnis, S. Brannan, and P. Jerabek Mood challenge in remitted unipolar depression unmasks disease-specific cerebral blood flow abnormalities Am Psychiatry 159 2002 1830 1840
80. M. Liotti, H.S. Mayberg, and S. McGinnis Unmasking disease-specific cerebral blood flow abnormalities: mood challenge in patients with remitted unipolar depression Am J Psychiatry 159 2002 1830 1840
81. N. Long, C. MacDonald, and K. Chamberlain Prevalence of posttraumatic stress disorder, depression and anxiety in a community sample of New Zealand Vietnam War veterans Aust N Z J Psychiatry 30 1996 253 256
82. I. Marks, K. Lovell, H. Noshirvani, M. Livanou, and S. Thrasher Treatment of posttraumatic stress disorder by exposure and/or cognitive restructuring: a controlled study Arch Gen Psychiatry 55 1998 317 325
83. R.D. Marshall, K.L. Beebe, M. Oldham, and R. Zaninelli Efficacy and safety of paroxetine treatment for chronic PTSD: a fixed-dose, placebo-controlled study Am J Psychiatry 158 2001 1982 1988
84. R.D. Marshall, F.R. Schneider, and B.A. Fallon An open trial of paroxetine in patients with noncombat-related, chronic posttraumatic stress disorder J Clin Psychopharmacol 18 1998 10 18
85. J.W. Mason, E.L. Giller, T.R. Kosten, R.B. Ostroff, and L. Podd Urinary free-cortisol levels in posttraumatic stress disorder patients J Nerv Ment Dis 174 1986 145 149
86. H.S. Mayberg Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain-based algorithms for diagnosis and optimised treatment Br Med Bull 65 2003 193 207
87. H.S. Mayberg, S.K. Brannan, R.K. Mahurin, and S. McGinnin Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response Biol Psychiatry 48 2000 830 843
88. H.S. Mayberg, S.K. Brannan, and J.L. Tekell Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response Biol Psychiatry 48 2000 830 843
89. H.S. Mayberg, M. Liotti, and S.K. Brannan Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness Am J Psychiatry 156 1999 675 682
90. H.S. Mayberg, J.A. Silva, and S.K. Brannan The functional neuroanatomy of the placebo effect Am J Psychiatry 159 2002 728 737
91. J. McCauley, D.E. Kern, and K. Kolodner Clinical characteristics of women with a history of childhood abuse: unhealed wounds JAMA 277 1997 1362 1368
92. J.P. McCullough Cognitive-behavioral analysis system of psychotherapy: an interactional treatment approach for dysthymic disorder Psychiatry 47 1984 234 250
93. A.E. McHolm, H.L. MacMillan, and E. Jamieson The relationship between childhood physical abuse and suicidality among depressed women: results from a community sample Am J Psychiatry 160 2003 933 938
94. J.C. McMillen Better for it: how people benefit from adversity? Soc Work 44 1999 455 468
95. D. Meichenbaum Cognitive behavior modification 1974 General Learning Press Morristown (NJ)
96. Merriam-Webster's Collegiate Dictionary, 10th ed. Springfield (MA): Merriam-Webster; 1993.
97. C.B. Nemeroff Clinical significance of psychoneuroendocrinology in psychiatry: focus on the thyroid and adrenal J Clin Psychiatry 50 Suppl 1989 13 20 discussion: 21-2
98. C.B. Nemeroff, C.M. Heim, M.E. Thase, D.N. Klein, J. Rush, and A.F. Schatzberg Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma Proc Natl Acad Sci USA 100 2003 14293 14296
99. J.F. Neumaier, E. Edwards, and P.M. Plotsky 5-HT(1B) mrna regulation in two animal models of altered stress reactivity Biol Psychiatry 51 2002 902 908
100. F.H. Norris, M.J. Friedman, P.J. Watson, C.M. Byrne, E. Diaz, and K. Kaniasty 60,000 disaster victims speak. Part I. An empirical review of the empirical literature, 1981-2001 Psychiatry 65 2002 207 239
101. C.S. North, S.J. Nixon, and S. Shariat Psychiatric disorders among survivors of the Oklahoma City bombing JAMA 282 1999 755 762
102. C.S. North, E.L. Spitznagel, and E.M. Smith A prospective study of coping after exposure to a mass murder episode Ann Clin Psychiatry 13 2001 81 87
103. C.F. Notestine, M.B. Stein, C.M. Kennedy, S.L. Archibald, and T.L. Jernigan Brain morphometry in female victims of intimate partner violence with and without posttraumatic stress disorder Biol Psychiatry 51 2002 1089 1101
104. D. Ongur, X. An, and J.L. Price Prefrontal cortical projections to the hypothalamus in macaque monkeys J Comp Neurol 401 1998 480 505
105. M.A. Oquendo, J.M. Friend, and B. Halberstam Association of comorbid posttraumatic stress disorder and major depression with greater risk for suicidal behavior Am J Psychiatry 160 2003 580 582
106. P. Ouimette, R. Cronkite, B.R. Henson, A. Prins, K. Gima, and R.H. Moos Posttraumatic stress disorder and health status among female and male medical patients J Traumatic Stress 17 2004 1 9
107. A. Perkonigg, R.C. Kessler, S. Storz, and H.-U. Wittchen Traumatic events and post-traumatic stress disorder in the community: prevalence, risk factors and comorbidity Acta Psychiatr Scand 101 2000 46 59
108. C. Pihoker, M.J. Owens, C.M. Kuhn, S.M. Schanberg, and C.B. Nemeroff Maternal separation in neonatal rats elicits activation of the hypothalamic-pituitary-adrenocortical axis: a putative role for corticotropin-releasing factor Psychoneuroendocrinology 18 1993 485 493
109. R.K. Pitman Investigating the pathogenesis of posttraumatic stress disorder with neuroimaging J Clin Psychiatry 62 2001 47 54
110. S.B. Plichta, and M. Falik Prevalence of violence and its implications for women's health Womens Health Issues 11 2001 244 258
111. H.G. Prigerson, P.K. Maciejewski, and R.A. Rosenheck Population attributable fractions of psychiatric disorders and behavioral outcomes associated with combat exposure among US men Am J Public Health 92 2002 59 63
112. F.C. Raadsheer, W.J. Hoogendijk, and F.C. Stam Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients Neuroendocrinology 60 1994 436 444
113. P.A. Resick, P. Nishith, T.L. Weaver, M.C. Astin, and C.A. Feuer A comparison of cognitive-processing therapy with prolonged exposure and a waiting condition for the treatment of chronic posttraumatic stress disorder in female rape victims J Consulting Clin Psychol 70 2002 867 879
114. Rothbaum BO, Astin MC. Prolonged exposure versus EMDR for PTSD rape victims. In: Zoellner LA (Chair), Recent innovations in post traumatic stress disorder treatment. Paper presented at the 22nd national conference of the anxiety disorders association of America, Austin, TX; March 2002.
115. S.A. Safren, B.S. Gershuny, and P. Marzol History of childhood abuse in panic disorder, social phobia, and generalized anxiety disorder J Nerv Ment Dis 190 2002 453 456
116. L. Santarelli, M. Saxe, and C. Gross Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants Science 301 2003 805 809
117. W.E. Schlenger, J.M. Caddell, and L. Ebert Psychological reactions to terrorist attacks: findings from the National Study of Americans' Reactions to September 11 JAMA 288 2002 581 588
118. N. Schuff, T.C. Neylan, and M.A. Lenoci Decreased hippocampal N-acetylaspartate in the absence of atrophy in posttraumatic stress disorder Biol Psychiatry 50 2001 952 959
119. M.A. Schuster, B.D. Stein, and L. Jaycox A national survey of stress reactions after the September 11, 2001, terrorist attacks New Engl J Med 345 2001 1507 1512
120. D.A. Seminowicz, H.S. Mayberg, and A.R. McIntosh Limbic-frontal circuitry in major depression: a path modeling metanalysis Neuroimage 22 2004 409 418
121. F. Shapiro Eye movement desensitization and reprocessing: basic principles, protocols, and procedures 1995 Guilford Press New York (NY)
122. L.M. Shin, P.S. Shin, and S. Heckers Hippocampal function in posttraumatic stress disorder Hippocampus 14 2004 292 300
123. R.C. Silver, E.A. Holman, and D.N. McIntosh Nationwide longitudinal study of psychological responses to September 11 JAMA 288 2002 1235 1244
124. T. Stefurak, and H. Mayberg Cortico-limbic-striatal dysfunction in depression: converging findings in basal ganglia disease & primary affective disorders M.A. Bedard Y. Agid Chouinard Mental & behavioral dysfunction in movement disorders 2003 Humanae Press Clifton, UK 321 338
125. M.B. Stein A 46-year-old man with anxiety and nightmares after a motor vehicle collision JAMA 288 2002 1513 1522
126. M.B. Stein, and C. Kennedy Major depressive and post-traumatic stress disorder comorbidity in female victims of intimate partner violence J Affect Disord 66 2001 133 138
127. M.B. Stein, J.R. Walker, and D.R. Forde Gender differences in susceptibility to posttraumatic stress disorder Behav Res Ther 38 2000 619 628
128. M.B. Stein, C. Koverola, C. Hanna, M.G. Torchia, and B. McClarty Hippocampal volume in women victimized by childhood sexual abuse Psychol Med 27 1997 951 959
129. M.B. Stein, R. Yehuda, C. Koverola, and C. Hanna Enhanced dexamethasone suppression of plasma cortisol in adult women traumatized by childhood sexual abuse Biol Psychiatry 42 1997 680 686
130. P. Tucker, R. Zaninelli, R. Yehuda, L. Ruggiero, K. Dillingham, and C.D. Pitts Paroxetine in the treatment of chronic posttraumatic stress disorder: results of a placebo-controlled, flexible-dosage trial J Clin Psychiatry 62 2001 860 868
131. Unpublished observations.
132. 2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex J Neurosci 17 1997 2785 2795
133. S. Vaisrub Editorial: Da Costa syndrome revisited JAMA 232 1975 164
134. N.E. Van Loey, C.J. Maas, A.W. Faber, and L.A. Taal Predictors of chronic posttraumatic stress symptoms following burn injury: results of a longitudinal study J Trauma Stress 16 2003 361 369
135. E. Vermetten, M. Vythilingam, S.M. Southwick, D.S. Charney, and J.D. Bremner Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder Biol Psychiatry 54 2003 693 702
136. G. Villareale, D.A. Hamilton, and H. Petropoulos Reduced hippocampal volume and total white matter in posttraumatic stress disorder Biol Psychiatry 15 2002 119 125
137. E.A. Walker, W. Katon, and J. Russo Health care costs associated with posttraumatic stress disorder symptoms in women Arch Gen Psychiatry 60 2003 369 374
138. S.J. Wolin The resilient self: how survivors of troubled families rise above adversity? 1993 Villard Books New York
139. C.S. Woolley, E. Gould, and B.S. McEwen Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons Brain Res 531 1990 225 231
140. R. Yehuda, B. Kahana, K. Binder-Brynes, S. Southwick, J. Mason, and E. Giller Low urinary cortisol excretion in Holocaust survivors with posttraumatic stress disorder Am J Psychiatry 152 1995 982 990
141. R. Yehuda, S.M. Southwick, J.H. Krystal, D. Bremner, D.S. Charney, and J.W. Mason Enhanced suppression of cortisol following dexamethasone administration in posttraumatic stress disorder Am J Psychiatry 150 1993 83 86