Distinct conformations of the corticotropin releasing factor type 1 receptor adopted following agonist and antagonist binding are differentially regulated

Journal of Biological Chemistry

Volumn 280, Issue 12, 2005, Pages 11560-11568

  Perry, Stephen J ^a   Junger, Sachiko ^a   Kohout, Trudy A ^a   Hoare, Sam R J ^a   Struthers, R Scott ^a   Grigoriadis, Dimitri E ^a   Maki, Richard A ^a  

^a NEUROCRINE BIOSCIENCES INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL MEMBRANES; CHEMICAL ACTIVATION; CONFORMATIONS; MOLECULAR BIOLOGY;

ASTRESSIN BINDING; CORTICOTROPIN RELEASING FACTOR (CRF); HIGH AFFINITY BINDING; INTEMALIZATION; PHOSPHORYLATION;

PROTEINS;

ACTIVIN RECEPTOR 2; ASTRESSIN; BETA ARRESTIN; CHIMERIC PROTEIN; CLATHRIN; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; G PROTEIN COUPLED RECEPTOR;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANXIETY DISORDER; ARTICLE; CAVEOLA; CONTROLLED STUDY; DEPRESSION; HUMAN; HUMAN CELL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INTERNALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR DOWN REGULATION;

ANIMALS; CHO CELLS; CORTICOTROPIN-RELEASING HORMONE; CRICETINAE; ENDOCYTOSIS; HUMANS; MICE; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE;

EID: 15744377605     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M412914200     Document Type: Article

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