Functional upregulation of system xc- by fibroblast growth factor-2

Neuropharmacology

Volumn 62, Issue 2, 2012, Pages 901-906

  Liu, Xiaoqian ^a   Resch, Jon ^a   Rush, Travis ^a   Lobner, Doug ^a  

^a MARQUETTE UNIVERSITY   (United States)

Author keywords

Cystine; FGF 2; Glutamate; Glutathione; System xc

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 CARBOXYPHENYLGLYCINE; ANTIPORTER; BRAIN DERIVED NEUROTROPHIC FACTOR; CARBON 14; CYCLOHEXIMIDE; CYSTINE; CYSTINE GLUTAMATE ANTIPORTER; FIBROBLAST GROWTH FACTOR 2; GLUTATHIONE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NEU DIFFERENTIATION FACTOR; NEUROTROPHIN 4; PHOSPHATIDYLINOSITOL 3 KINASE; SOMATOMEDIN; UNCLASSIFIED DRUG;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; CONTROLLED STUDY; FETUS; KINETICS; MICROGLIA; MOUSE; NERVE CELL CULTURE; NEUROTROPISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

AMINO ACID TRANSPORT SYSTEM Y+; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; CEREBRAL CORTEX; COCULTURE TECHNIQUES; CYCLOHEXIMIDE; CYSTEINE; FIBROBLAST GROWTH FACTOR 2; INSULIN-LIKE GROWTH FACTOR I; MICE; NERVE GROWTH FACTORS; NEUREGULIN-1; NEUROGLIA; NEURONS; PROTEIN BIOSYNTHESIS; UP-REGULATION;

EID: 84855969844     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.09.019     Document Type: Article

References (60)

1. E.S. Anton, M.A. Marchionni, K.F. Lee, and P. Rakic Role of GGF/neuregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex Development 124 1997 3501 3510
2. J.S. Bains, and C.A. Shaw Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death Brain Res. Brain Res. Rev. 25 1997 335 358
3. D.A. Baker, K. McFarland, R.W. Lake, H. Shen, X.C. Tang, S. Toda, and P.W. Kalivas Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse Nat. Neurosci. 6 2003 743 749
4. N. Ballatori, S.M. Krance, S. Notenboom, S. Shi, K. Tieu, and C.L. Hammond Glutathione dysregulation and the etiology and progression of human diseases Biol. Chem. 390 2009 191 214
5. S.W. Barger, and A.S. Basile Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function J. Neurochem. 76 2001 846 854
6. J.H. Cabungcal, D. Preissmann, C. Delseth, M. Cuénod, K.Q. Do, and F. Schenk Transitory glutathione deficit during brain development induces cognitive impairment in juvenile and adult rats: relevance to schizophrenia Neurobiol. Dis. 26 2007 634 645
7. 2+ responses to AMPA and NMDA in hippocampal neurons J. Neurochem. 65 1995 2525 2536
8. D. Choi Antagonizing excitotoxicity: a therapeutic strategy for stroke? Mt. Sinai J. Med. 65 1998 133 138
9. D.W. Choi, M. Maulucci-Gedde, and A.R. Kriegstein Glutamate neurotoxicity in cortical cell culture J. Neurosci. 7 1987 357 368
10. W.M. Clark, J.D. Schim, S.E. Kasner, and S.J. Victor Trafermin in acute ischemic stroke: results of a phase II/III randomized efficacy study (Abstract) Neurology 54 2000 A88
11. O.M. Dean, M. van den Buuse, A.I. Bush, D.L. Copolov, F. Ng, S. Dodd, and M. Berk A role for glutathione in the pathophysiology of bipolar disorder and schizophrenia? Animal models and relevance to clinical practice Curr. Med. Chem. 16 2009 2965 2976
12. M. Domercq, M.V. Sanchez-Gomez, C. Sherwin, E. Etxebarria, R. Fern, and C. Matute System xc- and glutamate transporter inhibition mediates microglial toxicity to oligodendrocytes J. Immunol. 178 2007 6549 6556
13. R. Dringen Metabolism and functions of glutathione in brain Prog. Neurobiol. 6 2000 649 671
14. R. Dringen, and J. Hirrlinger Glutathione pathways in the brain Biol. Chem. 384 2003 505 516
15. R. Dringen, B. Pfeiffer, and B. Hamprecht Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione J. Neurosci. 19 1999 562 569
16. L.L. Dugan, V.M.G. Bruno, S.M. Amagasu, and R.G. Giffard Glia modulate the response of murine cortical neurons to excitotoxicity: glia exacerbate AMPA neurotoxicity J. Neurosci. 15 1995 4545 4555
17. M.F. Favata, K.Y. Horiuchi, E.J. Manos, A.J. Daulerio, D.A. Stradley, W.S. Feeser, D.E. Van Dyk, W.J. Pitts, R.A. Earl, F. Hobbs, R.A. Copeland, R.L. Magolda, P.A. Scherle, and J.M. Trzaskos Identification of a novel inhibitor of mitogen-activated protein kinase kinase J. Biol. Chem. 273 1998 18623 18632
18. B. Fogal, J. Li, D. Lobner, L.D. McCullough, and S.J. Hewett System x(c)- activity and astrocytes are necessary for interleukin-1 beta-mediated hypoxic neuronal injury J. Neurosci. 27 2007 10094 10105
19. F. Fumagalli, L. Pasquale, G. Racagni, and M.A. Riva Dynamic regulation of fibroblast growth factor 2 (FGF-2) gene expression in the rat brain following single and repeated cocaine administration J. Neurochem. 96 2006 996 1004
20. F. Gaughran, J. Payne, P.M. Sedgwick, D. Cotter, and M. Berry Hippocampal FGF-2 and FGFR1 mRNA expression in major depression, schizophrenia and bipolar disorder Brain Res. Bull. 70 2006 221 227
21. A.M. Gonzalez, M. Berry, P.A. Maher, A. Logan, and A. Baird A comprehensive analysis of the distribution of FGF-2 and FGFR1 in the rat brain Brain Res. 701 1995 201 226
22. M.E. Hamby, T.F. Uliasz, S.J. Hewett, and J.A. Hewett Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytes J. Neurosci. Methods 150 2006 128 137
23. K. Hashimoto, E. Shimizu, N. Komatsu, M. Nakazato, N. Okamura, H. Watanabe, C. Kumakiri, N. Shinoda, S. Okada, N. Takei, and M. Iyo Increased levels of serum basic fibroblast growth factor in schizophrenia Psychiatry Res. 120 2003 211 218
24. R.G. Hu, J. Lim, P.J. Donaldson, and M. Kalloniatis Characterization of the cystine/glutamate transporter in the outer plexiform layer of the vertebrate retina Eur. J. Neurosci. 28 2008 1491 1502
25. N.A. Jackman, T.F. Uliasz, J.A. Hewett, and S.J. Hewett Regulation of system x(c)(-)activity and expression in astrocytes by interleukin-1β: implications for hypoxic neuronal injury Glia 58 2010 1806 1815
26. J. Jarosik, B. Legutko, S. Werner, K. Unsicker, and O. von Bohlen Und Halbach Roles of exogenous and endogenous FGF-2 in animal models of depression Restor. Neurol. Neurosci. 29 2011 153 165
27. J. Kodydková, L. Vávrová, M. Zeman, R. Jirák, J. Macásek, B. Stanková, E. Tvrzická, and A. Zák Antioxidative enzymes and increased oxidative stress in depressive women Clin. Biochem. 42 2009 1368 1374
28. J.Y. Koh, B.J. Gwag, D. Lobner, and D.W. Choi Potentiated necrosis of cultured cortical neurons by neurotrophins Science 268 1995 573 575
29. A. Lau, and M. Tymianski Glutamate receptors, neurotoxicity and neurodegeneration Pflugers Arch. 460 2010 525 542
30. J. Lewerenz, M. Klein, and A. Methner Cooperative action of glutamate transporters and cystine/glutamate antiporter system Xc- protects from oxidative glutamate toxicity J. Neurochem. 98 2006 916 925
31. X.Q. Liu, T. Rush, J. Ciske, and D. Lobner Selective death of cholinergic neurons induced by beta-methylamino-L-alanine Neuroreport 21 2010 55 58
32. D. Lobner Comparison of the LDH and MTT assays for quantifying cell death: validity for neuronal apoptosis? J. Neurosci. Meth. 96 2000 147 152
33. D. Lobner Mechanisms of beta-N-methylamino-L-alanine induced neurotoxicity Amytroph. Lateral Scler. 10 Suppl. 2 2009 56 60
34. D. Lobner, and C. Ali Mechanisms of bFGF and NT-4 potentiation of necrotic neuronal death Brain Res. 954 2002 42 50
35. D. Lobner, S. Golner, and J. Hjelmhaug Neurotrophic factor effects on oxidative stress-induced neuronal death Neurochem. Res. 28 2003 749 756
36. A. Madayag, K.S. Kau, D. Lobner, J.R. Mantsch, S. Wisniewski, and D.A. Baker Drug-induced plasticity contributing to heightened relapse susceptibility: neurochemical changes and augmented reinstatement in high-intake rats J. Neurosci. 30 2010 210 217
37. M. Maes, I. Mihaylova, M. Kubera, M. Uytterhoeven, N. Vrydags, and E. Bosmans Lower whole blood glutathione peroxidase (GPX) activity in depression, but not in myalgic encephalomyelitis/chronic fatigue syndrome: another pathway that may be associated with coronary artery disease and neuroprogression in depression Neuro. Endocrinol. Lett. 32 2011 133 140
38. A. Massie, A. Schallier, S.W. Kim, R. Fernando, S. Kobayashi, H. Beck, D. De Bundel, K. Vermoesen, S. Bannai, I. Smolders, M. Conrad, N. Plesnila, H. Sato, and Y. Michotte Dopaminergic neurons of system x(c) - deficient mice are highly protected against 6-hydroxydopamine-induced toxicity FASEB J. 25 2011 1359 1369
39. A. Massie, A. Schallier, B. Mertens, K. Vermoesen, S. Bannai, H. Sato, I. Smolders, and Y. Michotte Time-dependent changes in striatal xCT protein expression in hemi-Parkinson rats Neuroreport 19 2008 1589 1592
40. M.P. Mattson, K.N. Kumar, H. Wang, B. Cheng, and E.K. Michaelis Basic FGF regulates the expression of a functional 71 kDa NMDA receptor protein that mediates calcium influx and neurotoxicity in hippocampal neurons Neuroscience 13 1993 4575 4588
41. T.H. Murphy, and J.M. Baraban Glutamate toxicity in immature cortical neurons precedes development of glutamate receptor currents Brain Res. Dev. Brain Res. 57 1990 146 150
42. T.H. Murphy, R.L. Schnaar, and J.T. Coyle Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake FASEB J. 4 1990 1624 1633
43. Y. Ohkubo, A.O. Uchida, D. Shin, J. Partanen, and F.M. Vaccarino Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse J. Neurosci. 24 2004 6057 6069
44. Z. Pan, and R. Perez-Polo Role of nerve growth factor in oxidant homeostasis: glutathione metabolism J. Neurochem. 61 1993 1713 1721
45. D. Piani, and A. Fontana Involvement of the cystine transport system xc- in the macrophage-induced glutamate-dependent cytotoxicity to neurons J. Immunol. 152 1994 3578 3585
46. S. Qin, C. Colin, I. Hinners, A. Gervais, C. Cheret, and M. Mallat System Xc- and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-beta peptide 1-40 J. Neurosci. 26 2006 3345 3356
47. M. Raffa, F. Atig, A. Mhalla, A. Kerkeni, and A. Mechri Decreased glutathione levels and impaired antioxidant enzyme activities in drug-naive first-episode schizophrenic patients BMC Psychiatry 11 2011 124
48. R.R. Ratan, T.H. Murphy, and J.M. Baraban Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione J. Neurosci. 14 1994 4385 4392
49. T. Rush, X.Q. Liu, J. Hjelmhaug, and D. Lobner Mechanisms of chlorpyrifos and diazinon induced neurotoxicity in cortical culture Neuroscience 166 2010 899 906
50. J.I. Sagara, K. Miura, and S. Bannai Maintenance of neuronal glutathione by glial cells J. Neurochem. 61 1993 1672 1676
51. J.P. Schwartz, and D.J. Wilson Preparation and characterization of type 1 astrocytes cultured from adult rat cortex, cerebellum, and striatum Glia 5 1992 75 80
52. A.Y. Shih, H. Erb, X. Sun, S. Toda, P.W. Kalivas, and T.H. Murphy Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation J. Neurosci. 26 2006 10514 10523
53. A.F. Terwisscha van Scheltinga, S.C. Bakker, and R.S. Kahn Fibroblast growth factors in schizophrenia Schizophr. Bull. 36 2010 1157 1166
54. C.A. Turner, S.B. Flagel, S.M. Clinton, H. Akil, and S.J. Watson Cocaine interacts with the novelty-seeking trait to modulate FGFR1 gene expression in the rat Neurosci. Lett. 446 2008 105 107
55. C.J. Vlahos, W.F. Matter, K.Y. Hui, and R.F. Brown A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4- one (LY294002) J. Biol. Chem. 269 1994 5241 5248
56. K. Waite, and B.J. Eickholt The neurodevelopmental implications of PI3K signaling Curr. Top. Microbiol. Immunol. 346 2010 245 265
57. H. Xue, and C.J. Field New role of glutamate as an immunoregulator via glutamate receptors and transporters Front Biosci. (Schol Ed) 3 2011 1007 1020
58. P. Yuan, R. Zhou, Y. Wang, X. Li, J. Li, G. Chen, X. Guitart, and H.K. Manji Altered levels of extracellular signal-regulated kinase signaling proteins in postmortem frontal cortex of individuals with mood disorders and schizophrenia J. Affect. Disord. 124 2010 164 169
59. S. Zechel, S. Werner, K. Unsicker, and O. von Bohlen und Halbach Expression and functions of fibroblast growth factor 2 (FGF-2) in hippocampal formation Neuroscientist 16 2010 357 373
60. Y. Zhang, T. Tatsuno, J.M. Carney, and M.P. Mattson Basic FGF, NGF, and IGF's protect hippocampal and cortical neurons against iron-induced degeneration J. Cereb. Blood Flow Metab. 13 1993 378 388