Association between ABCB1 gene polymorphisms and fentanyl's adverse effects in Turkish patients undergoing spinal anesthesia

Gene

Volumn 493, Issue 2, 2012, Pages 273-277

  Kesimci, E ^a   Engin, A B ^b   Kanbak, O ^a   Karahalil, B ^b  

^a ATATURK TRAINING AND RESEARCH HOSPITAL   (Turkey)

^b GAZI UNIVERSITY   (Turkey)

Author keywords

ABCB1 polymorphism; Fentanyl; Spinal anesthesia

Indexed keywords

FENTANYL; OXYGEN;

ADULT; ALLELE; ARTICLE; ATP BINDING CASSETTE TRANSPORTER GENE; BISPECTRAL INDEX; BREATHING RATE; CLINICAL ASSESSMENT; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; OXYGEN SATURATION; PH; PRIORITY JOURNAL; RESPIRATION DEPRESSION; RESPIRATORY TRACT DISEASE; SPINAL ANESTHESIA; TURKEY (REPUBLIC);

ANESTHESIA, SPINAL; ANESTHETICS, INTRAVENOUS; FEMALE; FENTANYL; GENOTYPE; HUMANS; HYPNOTICS AND SEDATIVES; MALE; MIDDLE AGED; P-GLYCOPROTEIN; POLYMORPHISM, GENETIC; RESPIRATION; TURKEY;

EID: 84855857656     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2011.11.040     Document Type: Article

References (29)

1. Kalow W., Tang B.K., Endrenyi L. Hypothesis: comparisons of inter- and intra-individual variations can substitute for twin studies in drug research. Pharmacogenetics 1998, 8:283-289.
2. Akin M., Turgut S., Ayada C., et al. Relation between 3435 C>T multidrug resistance 1 gene polymorphism with high dose methylprednisolone treatment of childhood acute idiopathic thrombocytopenic purpura. Gene 2011, 487:80-83. (Epub 2011 Jun 21).
3. Xhemo E., Fajac A., Boire J.Y., et al. MDR View: a visualization of the polymorphisms of MDR1 (ABCB1) GENE in breast cancer. Conf. Proc. IEEE Eng. Med. Biol. Soc. 2007, 4592-4594.
4. Kato M., Fukuda T., Serretti A., et al. ABCB1 (MDR1) gene polymorphisms are associated with the clinical response to paroxetine in patients with major depressive disorder. Prog. Neuropsychopharmacol. Biol. Psychiatry 2008, 32:398-404.
5. Saricaoglu H., Yilmaz M., Karkucak M., et al. Investigation of ABCB1 gene polymorphism with colchicine response in Behçet's disease. Genet. Mol. Res. 2011, 10:1-6.
6. Marzolini C., Paus E., Buclin T., et al. Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance. Clin. Pharmacol. Ther. 2004, 75:13-33.
7. Pauli-Magnus C., Feiner J., Brett C., et al. No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects. Clin. Pharmacol. Ther. 2003, 74:487-498.
8. Westerlund M., Belin A.C., Anvret A., et al. Association of a polymorphism in the ABCB1 gene with Parkinsons disease. Parkinsonism Relat. Disord. 2009, 15:422-424.
9. Kharasch E.D., Hoffer C., Altuntas T.G., et al. Quinidine as a probe for the role of P-glycoprotein in the intestinal absorption and clinical effects of fentanyl. J. Clin. Pharmacol. 2004, 44:224-233.
10. Cirella V.N., Pantuck C.B., Lee Y.J., et al. Effects of cyclosporine on anesthetic action. Anesth. Analg. 1987, 66:703-706.
11. Mayer U., Wagenaar E., Dorobek B., et al. Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833. J. Clin. Investig. 1997, 100:2430-2436.
12. Henthorn T.K., Liu Y., Mahapatro M., et al. Active transport of fentanyl by the blood-brain barrier. J. Pharmacol. Exp. Ther. 1999, 289:1084-1089.
13. Yamazaki M., Neway W.E., Ohe T., et al. In vitro substrate identification studies for p-glycoprotein-mediated transport: species difference and predictability of in vivo results. J. Pharmacol. Exp. Ther. 2001, 296:723-735.
14. Taniguchi K., Wada M., Kohno K., et al. A human canalicular multispecific anion transporter (cMOAT) gene is overexpressed in cisplatin resistant human cancer cell lines with decreased drug accumulation. Cancer Res. 1996, 56:4124-4129.
15. Park H.J., Shinn H.K., Ryu S.H., et al. Genetic polymorphisms in the ABCB1 gene and the effects of fentanyl in Koreans. Clin. Pharmacol. Ther. 2007, 81:539-546.
16. Sigl J.C., Chamoun N.G. An introduction to bispectral analysis for the electroencephalogram. J. Clin. Monit. 1994, 10:392-404.
17. Kocabaş N.A., Karahalil B. XRCC1 Arg399Gln genetic polymorphism in a Turkish population. Int. J. Toxicol. 2006, 25:419-422.
18. Gümüş-Akay G., Rüstemoǧlu A., Karadaǧ A., et al. Genotype and allele frequencies of MDR1 gene C1236T polymorphism in a Turkish population. Genet. Mol. Res. 2008, 7:1193-1199.
19. Cascorbi I., Gerloff T., Johne A., et al. Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin. Pharmacol. Ther. 2001, 69:169-174.
20. Sia A.T., Sng B.L., Lim E.C., et al. The influence of ATP-binding cassette sub-family B member-1 (ABCB1) genetic polymorphisms on acute and chronic pain after intrathecal morphine for caesarean section: a prospective cohort study. Int. J. Obstet. Anesth. 2010, 19:254-260. (Epub 2010 Jun 2).
21. Dagenais C., Graff C.L., Pollack G.M. Variable modulation of opioid brain uptake by P-glycoprotein in mice. Biochem. Pharmacol. 2004, 67:269-276.
22. Kosarac B., Fox A.A., Collard C.D. Effect of genetic factors on opioid action. Curr. Opin. Anaesthesiol. 2009, 22:476-482.
23. Sadeque A.J., Wandel C., He H., et al. Increased drug delivery to the brain by P-glycoprotein inhibition. Clin. Pharmacol. Ther. 2000, 68:231-237.
24. Kharasch E.D., Hoffer C., Whittington D., et al. Role of P-glycoprotein in the intestinal absorption and clinical effects of morphine. Clin. Pharmacol. Ther. 2003, 74:543-554.
25. Kharasch E.D., Hoffer C., Altuntas T.G., et al. Quinidine as a probe for the role of P-glycoprotein in the intestinal absorption. J. Clin. Pharmacol. 2004, 44:224-233.
26. Elkiweri I.A., Zhang Y.L., Christians U., et al. Competitive substrates for P-glycoprotein and organic anion protein transporters differentially reduce blood organ transport of fentanyl and loperamide: pharmacokinetics and pharmacodynamics in Sprague-Dawley rats. Anesth. Analg. 2009, 108:149-159.
27. Kharasch E.D., Hoffer C., Whittington D. The effect of quinidine, used as a probe for the involvement of P-glycoprotein, on the intestinal absorption and pharmacodynamics of methadone. Br. J. Clin. Pharmacol. 2004, 57:600-610.
28. Hamabe W., Maeda T., Kiguchi N., et al. Negative relationship between morphine analgesia and P-glycoprotein expression levels in the brain. J. Pharmacol. Sci. 2007, 105:353-360. (Epub 2007 Dec 8).
29. Consales G., Chelazzi C., Rinaldi S., et al. Bispectral index compared to Ramsay score for sedation monitoring in intensive care units. Minerva Anestesiol. 2006, 72:329-336.