Potent galloyl-based selective modulators targeting multidrug resistance associated protein 1 and P-glycoprotein

Journal of Medicinal Chemistry

Volumn 55, Issue 1, 2012, Pages 424-436

  Pellicani, Raffaella Zoe ^a   Stefanachi, Angela ^a   Niso, Mauro ^a   Carotti, Angelo ^a   Leonetti, Francesco ^a   Nicolotti, Orazio ^a   Perrone, Roberto ^a   Berardi, Francesco ^a   Cellamare, Saverio ^a   Colabufo, Nicola Antonio ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 (3,4 DIHYDROXYPHENYL) 5 [[2 (3,4 DIMETHOXYPHENYL)ETHYL]METHYLAMINO] 2 ISOPROPYLPENTANENITRILE; 3 HYDROXY 4 METHOXY N (3 NITROBIPHENYL 4 YL)BENZAMIDE; 3 METHOXY 5 [(3 NITROBIPHENYL 4 YLAMINO)METHYL]BENZENE 1,2 DIOL; 3 NITROBIPHENYL 4 CARBOXYLIC ACID (3,4 DIHYDROXY 5 METHOXYPHENYL)AMIDE; 3,4 DIHYDROXY 5 METHOXY N (2 NITRO 4 THIOPHEN 2 YLPHENYL)BENZAMIDE; 3,4 DIHYDROXY 5 METHOXY N (3 NITROBIPHENYL 4 YL)BENZAMIDE; 3,4 DIHYDROXY 5 METHOXY N (3' NITROBIPHENYL 4 YL)BENZAMIDE; 3,4 DIHYDROXY 5 METHOXY N (4 METHOXY 2 NITROPHENYL) BENZAMIDE; 3,4 DIHYDROXY 5 METHOXY N (4 NITROBIPHENYL 3 YL) BENZAMIDE; 3,4 DIHYDROXY N (3 NITROBIPHENYL 4 YL)BENZAMIDE; 3,4,5 TRIHYDROXY N (3 NITROBIPHENYL 4 YL)BENZAMIDE; 5 METHYOXY 3,4 DIOXOCYCLOHEXA 1,5 DIENECARBOXYLIC ACID (3 NITROBIPHENYL 4 YL)AMIDE; GALLAMIDE DERIVATIVE; GALLOYL DERIVATIVE; GLYCOPROTEIN P INHIBITOR; MULTIDRUG RESISTANCE PROTEIN 1; N (3 ACETYLAMINOBIPHENYL 4 YL) 3,4 DIHYDROXY 5 METHOXY BENZAMIDE; N (3 AMINOBIPHENYL 4 YL) 3,4 DIHYDROXY 5 METHOXYBENZAMIDE; N (3' ACETYL 3 NITROBIPHENYL 4 YL) 3,4 DIHYDROXY 5 METHOXYBENZAMIDE; N (3' ACETYL 3 NITROBIPHENYL 4 YL) 3,4,5 TRIHYDROBENZAMIDE; N (3',4' DIHYDROXY 3 NITROBIPHENYL 4 YL) 3,4 DIHYDROXY 5 METHOXYBENZAMIDE; N (3',4' DIHYDROXY 5' METHOXY 3 NITROBIPHENYL 4 YL) 3,4 DIHYDROXY 5 METHOXYBENZAMIDE; N (3',5' DIFLUORO 3 NITROBIPHENYL 4 YL)3.4 DIHYDROXY 5 METHOXYBENZAMIDE; N (4 BROMO 2 NITROPHENYL) 3,4 DIHYDROXY 5 METHOXYBENZAMIDE; N (4 BROMO 2 NITROPHENYL) 3,4,5 TRIHYDROXYBENZAMIDE; N BIPHENYL 4 YL 3,4 DIHYDROXY 5 METHOXYBENZAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERAPAMIL; VERLUKAST;

ARTICLE; CATALYSIS; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGENATION; IN VITRO STUDY; PROTON NUCLEAR MAGNETIC RESONANCE; SUZUKI REACTION;

ANILIDES; ANIMALS; ANTINEOPLASTIC AGENTS; BENZAMIDES; CELL LINE; DOGS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG STABILITY; ETHERS; GALLIC ACID; P-GLYCOPROTEIN; PYROGALLOL; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84855841424     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm201305y     Document Type: Article

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