Proanthocyanidin from Blueberry leaves suppresses expression of subgenomic hepatitis C virus RNA

Journal of Biological Chemistry

Volumn 284, Issue 32, 2009, Pages 21165-21176

  Takeshita, Masahiko ^a   Ishida, Yo Ichi ^b   Akamatsu, Ena ^b   Ohmori, Yusuke ^c   Sudoh, Masayuki ^c   Oto, Hirofumi ^d   Tsubouchi, Hirohito ^d   Kataoka, Hiroaki ^e  

^a Minami Nippon Dairy Co op Co Ltd   (Japan)

^b Miyazaki Prefectural Industrial Support Foundation   (Japan)

^c CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^d KAGOSHIMA UNIVERSITY   (Japan)

^e UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHRONIC HEPATITIS; CHRONIC LIVER DISEASE; DEGREE OF POLYMERIZATION; DOSE-DEPENDENT; EPICATECHIN; HCV RNA; HEPATITIS C VIRUS; HEPATOCELLULAR CARCINOMA; INITIAL METHANOL; ION TRAPS; METHANOL EXTRACT; NUCLEAR RIBONUCLEOPROTEIN; POLYMERIZATION DEGREE; POTENT INHIBITOR; PROANTHOCYANIDINS; PROTEIN GENES; RESISTANT GENES; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SPECIFIC ACTIVITY; THIOLYSIS; TIME OF FLIGHT ANALYSIS; VIRAL REPLICATION;

AGRICULTURAL PRODUCTS; CELL MEMBRANES; CHROMATOGRAPHIC ANALYSIS; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HYDROGEN; LIQUIDS; METHANOL; NUCLEIC ACIDS; OXYGEN; POLYMERIZATION; PURIFICATION; RNA; STRUCTURAL ANALYSIS;

CELL CULTURE;

CARBON; EPICATECHIN; GENE PRODUCT; HYDROGEN; METHANOL; NEOMYCIN RESISTANT PROTEIN; OXYGEN; PROANTHOCYANIDIN; PROTEIN NS 3; UNCLASSIFIED DRUG; VIRUS RNA;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; BLUEBERRY; DRUG ISOLATION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG PURIFICATION; DRUG SCREENING; DRUG STRUCTURE; FRACTIONATION; GENE EXPRESSION REGULATION; GENE REPRESSION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT LEAF; POLYMERIZATION; PRIORITY JOURNAL; REPLICON; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; VIRUS REPLICATION;

BLUEBERRY PLANT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; DRUG RESISTANCE, VIRAL; GENE EXPRESSION REGULATION, VIRAL; HEPACIVIRUS; INHIBITORY CONCENTRATION 50; MASS SPECTROMETRY; NEOMYCIN; PLANT EXTRACTS; PLANT LEAVES; POLYMERS; PROANTHOCYANIDINS; RNA, VIRAL; VIRUS REPLICATION;

HEPATITIS C VIRUS; VACCINIUM;

EID: 69249104937     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.004945     Document Type: Article

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