메뉴 건너뛰기




Volumn 119, Issue 2, 2012, Pages 434-444

HTLV-1 bZIP factor impairs cell-mediated immunity by suppressing production of Th1 cytokines

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HUMAN T CELL LEUKEMIA VIRUS 1 BASIC LEUCINE ZIPPER FACTOR; INTERLEUKIN 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN;

EID: 84855829713     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-05-357459     Document Type: Article
Times cited : (60)

References (50)
  • 1
    • 33947578030 scopus 로고    scopus 로고
    • Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation
    • DOI 10.1038/nrc2111, PII NRC2111
    • Matsuoka M, Jeang KT. Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation. Nat Rev Cancer. 2007;7(4):270-280. (Pubitemid 46480972)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.4 , pp. 270-280
    • Matsuoka, M.1    Jeang, K.-T.2
  • 2
    • 0017708061 scopus 로고
    • Adult T-cell leukemia: Clinical and hematologic features of 16 cases
    • Uchiyama T, Yodoi J, Sagawa K, Takatsuki K, Uchino H. Adult T-cell leukemia: clinical and hematologic features of 16 cases. Blood. 1977; 50(3):481-492. (Pubitemid 8180432)
    • (1977) Blood , vol.50 , Issue.3 , pp. 481-492
    • Uchiyama, T.1    Yodoi, J.2    Sagawa, K.3
  • 3
    • 0019254359 scopus 로고
    • Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma
    • DOI 10.1073/pnas.77.12.7415
    • Poiesz BJ, Ruscetti FW, Gazdar AF, Bunn PA, Minna JD, Gallo RC. Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sci U S A. 1980; 77(12):7415-7419. (Pubitemid 11131140)
    • (1980) Proceedings of the National Academy of Sciences of the United States of America , vol.77 , Issue.12 II , pp. 7415-7419
    • Poiesz, B.J.1    Ruscetti, F.W.2    Gazdar, A.F.3
  • 5
    • 0021995980 scopus 로고
    • Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis
    • Gessain A, Barin F, Vernant JC, et al. Antibodies to human T-lymphotropic virus type-I in patients with tropical spastic paraparesis. Lancet. 1985; 2(8452):407-410. (Pubitemid 15231248)
    • (1985) Lancet , vol.2 , Issue.8452 , pp. 407-410
    • Gessain, A.1    Barin, F.2    Vernant, J.C.3
  • 6
    • 0022578349 scopus 로고
    • HTLV-I associated myelopathy, a new clinical entity
    • Osame M, Usuku K, Izumo S, et al. HTLV-I associated myelopathy, a new clinical entity. Lancet. 1986;1(8488):1031-1032. (Pubitemid 16102987)
    • (1986) Lancet , vol.1 , Issue.8488 , pp. 1031-1032
    • Osame, M.1    Usuku, K.2    Izumo, S.3
  • 8
    • 0001978434 scopus 로고
    • ATL and HTLV-I-related diseases
    • Takatsuki K, ed. New York: Oxford University Press
    • Takatsuki K, Matsuoka M, Yamaguchi K. ATL and HTLV-I-related diseases. In: Takatsuki K, ed. Adult T-Cell Leukemia. New York: Oxford University Press; 1994:1-27.
    • (1994) Adult T-Cell Leukemia , pp. 1-27
    • Takatsuki, K.1    Matsuoka, M.2    Yamaguchi, K.3
  • 9
    • 0032500171 scopus 로고    scopus 로고
    • Persistent oligoclonal expansion of human T-cell leukemia virus type 1-infected circulating cells in patients with Tropical spastic paraparesis/HTLV-1 associated myelopathy
    • Cavrois M, Leclercq I, Gout O, Gessain A, Wain-Hobson S, Wattel E. Persistent oligoclonal expansion of human T-cell leukemia virus type 1-infected circulating cells in patients with tropical spastic paraparesis/HTLV-1- associated myelopathy. Oncogene. 1998;17(1):77-82. (Pubitemid 28360531)
    • (1998) Oncogene , vol.17 , Issue.1 , pp. 77-82
    • Cavrois, M.1    Leclercq, I.2    Gout, O.3    Gessain, A.4    Wain-Hobson, S.5    Wattel, E.6
  • 11
    • 25444436726 scopus 로고    scopus 로고
    • Human T-cell leukemia/lymphoma virus type 1 nonstructural genes and their functions
    • DOI 10.1038/sj.onc.1208977, PII 1208977
    • Nicot C, Harrod RL, Ciminale V, Franchini G. Human T-cell leukemia/lymphoma virus type 1 non-structural genes and their functions. Oncogene. 2005;24(39):6026-6034. (Pubitemid 43086120)
    • (2005) Oncogene , vol.24 , Issue.39 , pp. 6026-6034
    • Nicot, C.1    Harrod, R.L.2    Ciminale, V.3    Franchini, G.4
  • 12
    • 0036891865 scopus 로고    scopus 로고
    • The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription
    • DOI 10.1128/JVI.76.24.12813-12822.2002
    • Gaudray G, Gachon F, Basbous J, Biard-Piechaczyk M, Devaux C, Mesnard JM. The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription. J Virol. 2002;76(24):12813-12822. (Pubitemid 35386965)
    • (2002) Journal of Virology , vol.76 , Issue.24 , pp. 12813-12822
    • Gaudray, G.1    Gachon, F.2    Basbous, J.3    Biard-Piechaczyk, M.4    Devaux, C.5    Mesnard, J.-M.6
  • 14
    • 33646590024 scopus 로고    scopus 로고
    • HTLV-I antisense transcripts initiating in the 3′LTR are alternatively spliced and polyadenylated
    • Cavanagh MH, Landry S, Audet B, et al. HTLV-I antisense transcripts initiating in the 3′LTR are alternatively spliced and polyadenylated. Retrovirology. 2006;3:15.
    • (2006) Retrovirology , vol.3 , pp. 15
    • Cavanagh, M.H.1    Landry, S.2    Audet, B.3
  • 15
    • 44149114990 scopus 로고    scopus 로고
    • Characteristic expression of HTLV-1 basic zipper factor (HBZ) transcripts in HTLV-1 provirus-positive cells
    • Usui T, Yanagihara K, Tsukasaki K, et al. Characteristic expression of HTLV-1 basic zipper factor (HBZ) transcripts in HTLV-1 provirus-positive cells. Retrovirology. 2008;5:34.
    • (2008) Retrovirology , vol.5 , pp. 34
    • Usui, T.1    Yanagihara, K.2    Tsukasaki, K.3
  • 16
    • 52649110694 scopus 로고    scopus 로고
    • Transcriptional control of spliced and unspliced human T-cell leukemia virus type 1 bZIP factor (HBZ) gene
    • Yoshida M, Satou Y, Yasunaga J, Fujisawa J, Matsuoka M. Transcriptional control of spliced and unspliced human T-cell leukemia virus type 1 bZIP factor (HBZ) gene. J Virol. 2008;82(19): 9359-9368.
    • (2008) J Virol , vol.82 , Issue.19 , pp. 9359-9368
    • Yoshida, M.1    Satou, Y.2    Yasunaga, J.3    Fujisawa, J.4    Matsuoka, M.5
  • 17
    • 79952224982 scopus 로고    scopus 로고
    • HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo
    • Satou Y, Yasunaga J, Zhao T, et al. HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo. PLoS Pathog. 2011;7(2): e1001274.
    • (2011) PLoS Pathog , vol.7 , Issue.2
    • Satou, Y.1    Yasunaga, J.2    Zhao, T.3
  • 18
    • 63849210238 scopus 로고    scopus 로고
    • Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF-kappaB
    • Zhao T, Yasunaga J, Satou Y, et al. Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF-kappaB. Blood. 2009;113(12):2755-2764.
    • (2009) Blood , vol.113 , Issue.12 , pp. 2755-2764
    • Zhao, T.1    Yasunaga, J.2    Satou, Y.3
  • 19
    • 0242321897 scopus 로고    scopus 로고
    • The HBZ Factor of Human T-cell Leukemia Virus Type I Dimerizes with Transcription Factors JunB and c-Jun and Modulates Their Transcriptional Activity
    • DOI 10.1074/jbc.M307275200
    • Basbous J, Arpin C, Gaudray G, Piechaczyk M, Devaux C, Mesnard JM. The HBZ factor of human T-cell leukemia virus type I dimerizes with transcription factors JunB and c-Jun and modulates their transcriptional activity. J Biol Chem. 2003;278(44):43620-43627. (Pubitemid 37345988)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.44 , pp. 43620-43627
    • Basbous, J.1    Arpin, C.2    Gaudray, G.3    Piechaczyk, M.4    Devaux, C.5    Mesnard, J.-M.6
  • 20
    • 0032526336 scopus 로고    scopus 로고
    • T lymphocytes are required for protection of the vaginal mucosae and sensory ganglia of immune mice against reinfection with herpes simplex virus type 2
    • Milligan GN, Bernstein DI, Bourne N. T lymphocytes are required for protection of the vaginal mucosae and sensory ganglia of immune mice against reinfection with herpes simplex virus type 2. J Immunol. 1998;160(12):6093-6100. (Pubitemid 28298073)
    • (1998) Journal of Immunology , vol.160 , Issue.12 , pp. 6093-6100
    • Milligan, G.N.1    Bernstein, D.I.2    Bourne, N.3
  • 21
    • 59649121568 scopus 로고    scopus 로고
    • Dendritic cells and B cells maximize mucosal Th1 memory response to herpes simplex virus
    • Iijima N, Linehan MM, Zamora M, et al. Dendritic cells and B cells maximize mucosal Th1 memory response to herpes simplex virus. J Exp Med. 2008;205(13):3041-3052.
    • (2008) J Exp Med , vol.205 , Issue.13 , pp. 3041-3052
    • Iijima, N.1    Linehan, M.M.2    Zamora, M.3
  • 22
    • 0023791557 scopus 로고
    • Cloned L3T4+ T lymphocytes protect mice against Listeria monocytogenes by secreting IFN-gamma
    • Magee DM, Wing EJ. Cloned L3T4+ T lymphocytes protect mice against Listeria monocytogenes by secreting IFN-gamma. J Immunol. 1988;141(9):3203-3207.
    • (1988) J Immunol , vol.141 , Issue.9 , pp. 3203-3207
    • Magee, D.M.1    Wing, E.J.2
  • 23
    • 0031014332 scopus 로고    scopus 로고
    • Requirement of the initial production of gamma interferon in the generation of protective immunity of mice against Listeria monocytogenes
    • Yang J, Kawamura I, Mitsuyama M. Requirement of the initial production of gamma interferon in the generation of protective immunity of mice against Listeria monocytogenes. Infect Immun. 1997; 65(1):72-77. (Pubitemid 27008905)
    • (1997) Infection and Immunity , vol.65 , Issue.1 , pp. 72-77
    • Yang, J.1    Kawamura, I.2    Mitsuyama, M.3
  • 25
    • 0024688999 scopus 로고
    • Listeriosis in hematological malignancies: Report of two cases
    • Ikehara O, Endo K, Hakamada K. Listeriosis in hematological malignancies: report of two cases. Jpn J Clin Oncol. 1989;19(2):159-162.
    • (1989) Jpn J Clin Oncol , vol.19 , Issue.2 , pp. 159-162
    • Ikehara, O.1    Endo, K.2    Hakamada, K.3
  • 26
    • 0023681805 scopus 로고
    • Effects of various nucleosides on antiviral activity and metabolism of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil against herpes simplex virus types 1 and 2
    • Suzutani T, Machida H, Sakuma T, Azuma M. Effects of various nucleosides on antiviral activity and metabolism of 1-beta-D-arabinofuranosyl-E-5-(2- bromovinyl)uracil against herpes simplex virus types 1 and 2. Antimicrob Agents Chemother. 1988;32(10):1547-1551.
    • (1988) Antimicrob Agents Chemother , vol.32 , Issue.10 , pp. 1547-1551
    • Suzutani, T.1    Machida, H.2    Sakuma, T.3    Azuma, M.4
  • 27
    • 34547643957 scopus 로고    scopus 로고
    • Cytolysin-dependent escape of the bacterium from the phagosome is required but not sufficient for induction of the Th1 immune response against Listeria monocytogenes infection: Distinct role of listeriolysin o determined by cytolysin gene replacement
    • DOI 10.1128/IAI.01779-06
    • Hara H, Kawamura I, Nomura T, Tominaga T, Tsuchiya K, Mitsuyama M. Cytolysin-dependent escape of the bacterium from the phagosome is required but not sufficient for induction of the Th1 immune response against Listeria monocytogenes infection: distinct role of Listeriolysin O determined by cytolysin gene replacement. Infect Immun. 2007;75(8):3791-3801. (Pubitemid 47206276)
    • (2007) Infection and Immunity , vol.75 , Issue.8 , pp. 3791-3801
    • Hara, H.1    Kawamura, I.2    Nomura, T.3    Tominaga, T.4    Tsuchiya, K.5    Mitsuyama, M.6
  • 28
    • 23044516024 scopus 로고    scopus 로고
    • Halogenated thymidine analogues restore the expression of silenced genes without demethylation
    • DOI 10.1158/0008-5472.CAN-04-3495
    • Fan J, Kodama E, Koh Y, Nakao M, Matsuoka M. Halogenated thymidine analogues restore the expression of silenced genes without demethylation. Cancer Res. 2005;65(15):6927-6933. (Pubitemid 41060732)
    • (2005) Cancer Research , vol.65 , Issue.15 , pp. 6927-6933
    • Fan, J.1    Kodama, E.-I.2    Koh, Y.3    Nakao, M.4    Matsuoka, M.5
  • 29
    • 77957226429 scopus 로고    scopus 로고
    • Antiviral immune responses in the genital tract: Clues for vaccines
    • Iwasaki A. Antiviral immune responses in the genital tract: clues for vaccines. Nat Rev Immunol. 2010;10(10):699-711.
    • (2010) Nat Rev Immunol , vol.10 , Issue.10 , pp. 699-711
    • Iwasaki, A.1
  • 30
    • 0037384980 scopus 로고    scopus 로고
    • Progesterone increases susceptibility and decreases immune responses to genital herpes infection
    • DOI 10.1128/JVI.77.8.4558-4565.2003
    • Kaushic C, Ashkar AA, Reid LA, Rosenthal KL. Progesterone increases susceptibility and decreases immune responses to genital herpes infection. J Virol. 2003;77(8):4558-4565. (Pubitemid 36402805)
    • (2003) Journal of Virology , vol.77 , Issue.8 , pp. 4558-4565
    • Kaushic, C.1    Ashkar, A.A.2    Reid, L.A.3    Rosenthal, K.L.4
  • 31
    • 0030758821 scopus 로고    scopus 로고
    • Studies in listeriosis show the strong symbiosis between the innate cellular system and the T-cell response
    • DOI 10.1111/j.1600-065X.1997.tb00988.x
    • Unanue ER. Studies in listeriosis show the strong symbiosis between the innate cellular system and the T-cell response. Immunol Rev. 1997;158:11-25. (Pubitemid 27379539)
    • (1997) Immunological Reviews , vol.158 , pp. 11-25
    • Unanue, E.R.1
  • 32
    • 0028015936 scopus 로고
    • Studies with MHC-deficient knock-out mice reveal impact of both MHC I- and MHC II-dependent T cell responses on Listeria monocytogenes infection
    • Ladel CH, Flesch IE, Arnoldi J, Kaufmann SH. Studies with MHC-deficient knock-out mice reveal impact of both MHC I- and MHC II-dependent T cell responses on Listeria monocytogenes infection. J Immunol. 1994;153(7):3116-3122. (Pubitemid 24292536)
    • (1994) Journal of Immunology , vol.153 , Issue.7 , pp. 3116-3122
    • Ladel, C.H.1    Flesch, I.E.A.2    Arnoldi, J.3    Kaufmann, S.H.E.4
  • 33
    • 17044393922 scopus 로고    scopus 로고
    • Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells
    • Bettelli E, Dastrange M, Oukka M. Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci U S A. 2005;102(14):5138-5143.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.14 , pp. 5138-5143
    • Bettelli, E.1    Dastrange, M.2    Oukka, M.3
  • 34
    • 0035259694 scopus 로고    scopus 로고
    • Innate and acquired activation pathways in T cells
    • DOI 10.1038/84236
    • Nakanishi K. Innate and acquired activation pathways in T cells. Nat Immunol. 2001;2(2):140-142. (Pubitemid 33707932)
    • (2001) Nature Immunology , vol.2 , Issue.2 , pp. 140-142
    • Nakanishi, K.1
  • 35
    • 0025864430 scopus 로고
    • The human interferon-gamma gene contains an inducible promoter that can be transactivated by tax I and II
    • Brown DA, Nelson FB, Reinherz EL, Diamond DJ. The human interferon-gamma gene contains an inducible promoter that can be transactivated by tax I and II. Eur J Immunol. 1991;21(8):1879-1885.
    • (1991) Eur J Immunol , vol.21 , Issue.8 , pp. 1879-1885
    • Brown, D.A.1    Nelson, F.B.2    Reinherz, E.L.3    Diamond, D.J.4
  • 36
    • 25444512922 scopus 로고    scopus 로고
    • Deregulation of cell-signaling pathways in HTLV-1 infection
    • DOI 10.1038/sj.onc.1208975, PII 1208975
    • Hall WW, Fujii M. Deregulation of cell-signaling pathways in HTLV-1 infection. Oncogene. 2005; 24(39):5965-5975. (Pubitemid 43086114)
    • (2005) Oncogene , vol.24 , Issue.39 , pp. 5965-5975
    • Hall, W.W.1    Fujii, M.2
  • 37
    • 13944265035 scopus 로고    scopus 로고
    • HTLV-1 HBZ suppresses AP-1 activity by impairing both the DNA-binding ability and the stability of c-Jun protein
    • DOI 10.1038/sj.onc.1208297
    • Matsumoto J, Ohshima T, Isono O, Shimotohno K. HTLV-1 HBZ suppresses AP-1 activity by impairing both the DNA-binding ability and the stability of c-Jun protein. Oncogene. 2005;24(6):1001-1010. (Pubitemid 40313877)
    • (2005) Oncogene , vol.24 , Issue.6 , pp. 1001-1010
    • Matsumoto, J.1    Ohshima, T.2    Isono, O.3    Shimotohno, K.4
  • 38
    • 77954097645 scopus 로고    scopus 로고
    • Immunity and immunopathology to viruses: What decides the outcome?
    • Rouse BT, Sehrawat S. Immunity and immunopathology to viruses: what decides the outcome? Nat Rev Immunol. 2010;10(7):514-526.
    • (2010) Nat Rev Immunol , vol.10 , Issue.7 , pp. 514-526
    • Rouse, B.T.1    Sehrawat, S.2
  • 40
    • 13444280343 scopus 로고    scopus 로고
    • Hepatitis C virus core protein induces an anergic state characterized by decreased interleukin-2 production and perturbation of mitogen-activated protein kinase responses
    • DOI 10.1128/JVI.79.4.2230-2239.2005
    • Sundstrom S, Ota S, Dimberg LY, Masucci MG, Bergqvist A. Hepatitis C virus core protein induces an anergic state characterized by decreased interleukin-2 production and perturbation of mitogen-activated protein kinase responses. J Virol. 2005;79(4):2230-2239. (Pubitemid 40204580)
    • (2005) Journal of Virology , vol.79 , Issue.4 , pp. 2230-2239
    • Sundstrom, S.1    Ota, S.2    Dimberg, L.Y.3    Masucci, M.G.4    Bergqvist, A.5
  • 41
    • 67449107496 scopus 로고    scopus 로고
    • Vaccinia virus E3 suppressesexpression of diverse cytokines through inhibition of the PKR, NF-kappaB, and IRF3 pathways
    • Myskiw C, Arsenio J, van Bruggen R, Deschambault Y, Cao J. Vaccinia virus E3 suppressesexpression of diverse cytokines through inhibition of the PKR, NF-kappaB, and IRF3 pathways. J Virol. 2009;83(13):6757-6768.
    • (2009) J Virol , vol.83 , Issue.13 , pp. 6757-6768
    • Myskiw, C.1    Arsenio, J.2    Van Bruggen, R.3    Deschambault, Y.4    Cao, J.5
  • 42
    • 78650310661 scopus 로고    scopus 로고
    • HIV-1 trans-activator protein dysregulates IFN-gamma signaling and contributes to the suppression of autophagy induction
    • Li JC, Au KY, Fang JW, et al. HIV-1 trans-activator protein dysregulates IFN-gamma signaling and contributes to the suppression of autophagy induction. AIDS. 2011;25(1):15-25.
    • (2011) AIDS , vol.25 , Issue.1 , pp. 15-25
    • Li, J.C.1    Au, K.Y.2    Fang, J.W.3
  • 43
    • 0142197612 scopus 로고    scopus 로고
    • Regulation of IL4 gene expression by T cells and therapeutic perspectives
    • DOI 10.1038/nri1128
    • Li-Weber M, Krammer PH. Regulation of IL4 gene expression by T cells and therapeutic perspectives. Nat Rev Immunol. 2003;3(7):534-543. (Pubitemid 37328673)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.7 , pp. 534-543
    • Li-Weber, M.1    Krammer, P.H.2
  • 44
    • 77958494095 scopus 로고    scopus 로고
    • HTLV-1 bZIP factor gene: Its roles in HTLV-1 pathogenesis
    • Matsuoka M. HTLV-1 bZIP factor gene: its roles in HTLV-1 pathogenesis. Mol Aspects Med. 2010; 31(5):359-366.
    • (2010) Mol Aspects Med , vol.31 , Issue.5 , pp. 359-366
    • Matsuoka, M.1
  • 45
    • 2242423605 scopus 로고    scopus 로고
    • + regulatory T cells control Leishmania major persistence and immunity
    • DOI 10.1038/nature01152
    • Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature. 2002;420(6915):502-507. (Pubitemid 35477041)
    • (2002) Nature , vol.420 , Issue.6915 , pp. 502-507
    • Belkaid, Y.1    Piccirillo, C.A.2    Mendez, S.3    Shevach, E.M.4    Sacks, D.L.5
  • 47
    • 63949083672 scopus 로고    scopus 로고
    • Interferon-gamma: A historical perspective
    • Billiau A, Matthys P. Interferon-gamma: a historical perspective. Cytokine Growth Factor Rev. 2009;20(2):97-113.
    • (2009) Cytokine Growth Factor Rev , vol.20 , Issue.2 , pp. 97-113
    • Billiau, A.1    Matthys, P.2
  • 48
    • 0025875437 scopus 로고
    • Cryptosporidium infection in an adult mouse model. Independent roles for IFN-gamma and CD4+ T lymphocytes in protective immunity
    • Ungar BL, Kao TC, Burris JA, Finkelman FD. Cryptosporidium infection in an adult mouse model. Independent roles for IFN-gamma and CD4+ T lymphocytes in protective immunity. J Immunol. 1991;147(3):1014-1022.
    • (1991) J Immunol , vol.147 , Issue.3 , pp. 1014-1022
    • Ungar, B.L.1    Kao, T.C.2    Burris, J.A.3    Finkelman, F.D.4
  • 49
    • 0032193236 scopus 로고    scopus 로고
    • IFN-gamma is required for IL-12 responsiveness in mice with Candida albicans infection
    • Cenci E, Mencacci A, Del Sero G, et al. IFN-gamma is required for IL-12 responsiveness in mice with Candida albicans infection. J Immunol. 1998;161(7):3543-3550.
    • (1998) J Immunol , vol.161 , Issue.7 , pp. 3543-3550
    • Cenci, E.1    Mencacci, A.2    Del Sero, G.3
  • 50
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • DOI 10.1126/science.1083317
    • Sun JC, Bevan MJ. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science. 2003;300(5617):339-342. (Pubitemid 36433727)
    • (2003) Science , vol.300 , Issue.5617 , pp. 339-342
    • Sun, J.C.1    Bevan, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.