Ethanol withdrawal hastens the aging of cytochrome c oxidase

Neurobiology of Aging

Volumn 33, Issue 3, 2012, Pages 618.e21-618.e32

  Jung, Marianna E ^a   Ju, Xiaohua ^a   Metzger, Daniel B ^a   Simpkins, James W ^a  

^a UNIVERSITY OF NORTH TEXAS   (United States)

Author keywords

17 estradiol; Age; BAX (Bcl2 associated X protein); Brain aging; Cytochrome c; Cytochrome c oxidase; Ethanol withdrawal; Female rats; Mitochondria; Mitochondrial membrane swelling; Mitochondrial respiration

Indexed keywords

ALCOHOL; CYTOCHROME C OXIDASE; ESTRADIOL; MITOCHONDRIAL ENZYME; MITOCHONDRIAL PROTEIN; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE;

AGING; ALCOHOL CONSUMPTION; ALCOHOL WITHDRAWAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CEREBELLUM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; IMMUNOBLOTTING; MALE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; SPECTROPHOTOMETRY;

EID: 84855820638     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2011.02.002     Document Type: Article

References (55)

1. Chen J., Robinson N.C., Schenker S., Frosto T.A., Henderson G.I. Formation of 4-hydroxynonenal adducts with cytochrome c oxidase in rats following short-term ethanol intake. Hepatol. 1999, 29:1792-1798.
2. Davis R.E., Miller S., Herrnstadt C., Ghosh S.S., Fahy E., Shinobu L.A., Galasko D., Thal L.J., Beal M.F., Howell N., Parker W.D. Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease. Proc. Natl. Acad. Sci. U. S. A 1997, 94:4526-4531.
3. Dejean L.M., Martinez-Caballero S., Manon S., Kinnally K.W. Regulation of the mitochondrial apoptosis-induced channel, MAC, by BCL-2 family proteins. Biochim. Biophys. Acta 2006, 1762:191-201.
4. Deng Y., Wu X. Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria. Proc. Natl. Acad. Sci. U. S. A 2000, 97:12050-12055.
5. Diaz F. Cytochrome c oxidase deficiency: patients and animal models. Biochim. Biophys. Acta 2010, 1802:100-110.
6. Eun S.Y., Woo I.S., Jang H.S., Jin H., Kim M.Y., Kim H.J., Lee J.H., Chang K.C., Kim J.H., Seo H.G. Identification of cytochrome c oxidase subunit 6A1 as a suppressor of Bax-induced cell death by yeast-based functional screening. Biochem. Biophys. Res. Commun 2008, 373:58-63.
7. Finch C.E. The neurobiology of middle age has arrived. Neurobiol. Aging 2009, 30:515-520. discussion, 530-533.
8. Fukui H., Diaz F., Garcia S., Moraes C.T. Cytochrome c oxidase deficiency in neurons decreases both oxidative stress and amyloid formation in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. U. S. A 2007, 104:14163-14168.
9. Galluzzi L., Blomgren K., Kroemer G. Mitochondrial membrane permeabilization in neuronal injury. Nat. Rev. Neurosci 2009, 10:481-494.
10. Guarnieri C., Muscari C., Caldarera C.M. Mitochondrial production of oxygen free radicals in the heart muscle during the life span of the rat: peak at middle age. EXS. 1992, 62:73-77.
11. Hsu Y.T., Wolter K.G., Youle R.J. Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis. Proc. Natl. Acad. Sci. U. S. A 1997, 94:3668-3672.
12. Irwin R.W., Yao J., Hamilton R.T., Cadenas E., Brinton R.D., Nilsen J. Progesterone and estrogen regulate oxidative metabolism in brain mitochondria. Endocrinology 2008, 149:3167-3175.
13. Jaatinen P., Riikonen J., Riihioja P., Kajander O., Hervonen A. Interaction of aging and intermittent ethanol exposure on brain cytochrome c oxidase activity levels. Alcohol 2003, 29:91-100.
14. Jia L., Macey M.G., Yin Y., Newland A.C., Kelsey S.M. Subcellular distribution and redistribution of Bcl-2 family proteins in human leukemia cells undergoing apoptosis. Blood 1999, 93:2353-2359.
15. Jia L., Patwari Y., Srinivasula S.M., Newland A.C., Fernandes-Alnemri T., Alnemri E.S., Kelsey S.M. Bax translocation is crucial for the sensitivity of leukaemic cells to etoposide-induced apoptosis. Oncogene 2001, 20:4817-4826.
16. Jones T.T., Brewer G.J. Critical age-related loss of cofactors of neuron cytochrome C oxidase reversed by estrogen. Exp. Neurol 2009, 215:212-219.
17. Jung M.E., Agarwal R., Simpkins J.W. Ethanol withdrawal posttranslationally decreases the activity of cytochrome c oxidase in an estrogen reversible manner. Neurosci. Lett 2007, 416:160-164.
18. Jung M.E., Ju X., Simpkins J.W., Metzger D.B., Yan L.J., Wen Y. Ethanol withdrawal acts as an age-specific stressor to activate cerebellar P38 kinase. Neurobiol. Aging 2010, 10.1016/j.neurobiolaging.2010.01.005.
19. Jung M.E., Wilson A.M., Ju X., Wen Y., Metzger D.B., Simpkins J.W. Ethanol withdrawal provokes opening of the mitochondrial membrane permeability transition pore in an estrogen-preventable manner. J. Pharmacol. Exp. Ther 2009, 328:692-698.
20. Jung M.E., Yan L.J., Forster M.J., Simpkins J.W. Ethanol withdrawal provokes mitochondrial injury in an estrogen preventable manner. J. Bioenerg. Biomembr 2008, 40:35-44.
21. Jung M.E., Yang S.H., Brun-Zinkernagel A.M., Simpkins J.W. Estradiol protects against cerebellar damage and motor deficit in ethanol-withdrawn rats. Alcohol 2002, 26:83-93.
22. Kondagari G.S., Yang J., Taylor R.M. Investigation of cerebrocortical and cerebellar pathology in canine fucosidosis and comparison to aged brain. Neurobiol. Dis 2011, 41:605-615.
23. Kraemer K.L., Mayo-Smith M.F., Calkins D.R. Impact of age on the severity, course, and complications of alcohol withdrawal. Arch. Intern. Med 1997, 157:2234-2241.
24. Kroemer G., Galluzzi L., Brenner C. Mitochondrial membrane permeabilization in cell death. Physiol. Rev 2007, 87:99-163.
25. Kumarswamy R., Chandna S. Putative partners in Bax mediated cytochrome-c release: ANT, CypD, VDAC or none of them?. Mitochondrion 2009, 9:1-8.
26. Li K.Z., Lindenberger U., Freund A.M., Baltes P.B. Walking while memorizing: age-related differences in compensatory behavior. Psychol. Sci 2001, 12:230-237.
27. Liu J., Atamna H., Kuratsune H., Ames B.N. Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites. Ann. N.Y. Acad. Sci 2002, 959:133-166.
28. Lu A., Frink M., Choudhry M.A., Schwacha M.G., Hubbard W.J., Rue L.W., Bland K.I., Chaudry I.H. Mitochondria play an important role in 17beta-estradiol attenuation of H(2)O(2)-induced rat endothelial cell apoptosis. Am. J. Physiol. Endocrinol. Metab 2007, 292:E585-E593.
29. Manon S., Chaudhuri B., Guerin M. Release of cytochrome c and decrease of cytochrome c oxidase in Bax-expressing yeast cells, and prevention of these effects by coexpression of Bcl-xL. FEBS Lett. 1997, 415:29-32.
30. Manon S., Priault M., Camougrand N. Mitochondrial AAA-type protease Yme1p is involved in Bax effects on cytochrome c oxidase. Biochem. Biophys. Res. Commun 2001, 289:1314-1319.
31. Markowska A.L. Sex dimorphisms in the rate of age-related decline in spatial memory: relevance to alterations in the estrous cycle. J. Neurosci 1999, 19:8122-8133.
32. Menze M.A., Hutchinson K., Laborde S.M., Hand S.C. Mitochondrial permeability transition in the crustacean Artemia franciscana: absence of a calcium-regulated pore in the face of profound calcium storage. Am. J. Physiol. Regul. Integr. Comp. Physiol 2005, 289:R68-R76.
33. Page G.G., Ben-Eliyahu S. Increased surgery-induced metastasis and suppressed natural killer cell activity during proestrus/estrus in rats. Breast Cancer Res. Treat 1997, 45:159-167.
34. Rosse T., Olivier R., Monney L., Rager M., Conus S., Fellay I., Jansen B., Borner C. Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c. Nature 1998, 391:496-499.
35. Scovassi A.I., Soldani C., Veneroni P., Bottone M.G., Pellicciari C. Changes of mitochondria and relocation of the apoptosis-inducing factor during apoptosis. Ann. N.Y. Acad. Sci 2009, 1171:12-17.
36. Sen T., Sen N., Jana S., Khan F.H., Chatterjee U., Chakrabarti S. Depolarization and cardiolipin depletion in aged rat brain mitochondria: relationship with oxidative stress and electron transport chain activity. Neurochem. Int 2007, 50:719-725.
37. Sharma K., Mehra R.D. Long-term administration of estrogen or tamoxifen to ovariectomized rats affords neuroprotection to hippocampal neurons by modulating the expression of Bcl-2 and Bax. Brain Res. 2008, 1204:1-15.
38. Sharov V.G., Todor A.V., Imai M., Sabbah H.N. Inhibition of mitochondrial permeability transition pores by cyclosporine A improves cytochrome C oxidase function and increases rate of ATP synthesis in failing cardiomyocytes. Heart Fail. Rev 2005, 10:305-310.
39. Shi C., Xu J. Increased vulnerability of brain to estrogen withdrawal-induced mitochondrial dysfunction with aging. J. Bioenerg. Biomembr 2008, 40:625-630.
40. Sullivan E. Alcohol and drug dependence: Brain mechanisms and behavioral Impact. Neuropsychol. Rev 2007, 17:235-238.
41. Thayer W.S., Cummings J.J. Effects of chronic alcohol consumption on the steady-state kinetics properties of cytochrome oxidase in rat liver. Biochim. Biophys. Acta 1990, 1016:333-338.
42. Thomas M.P., Monaghan D.T., Morrisett R.A. Evidence for a causative role of N-methyl-d-aspartate receptors in an in vitro model of alcohol withdrawal hyperexcitability. J. Pharmacol. Exp. Ther 1998, 287:87-97.
43. Tron'ko M.D., Kovzun O.I., Hrinchenko I.e.M., Mykosha O.S. Effect of 17beta-estradiol on mRNA expression of Bax proapoptotic protein and DNA fragmentation level in the human adrenal cortex [in Ukranian]. Ukr. Biokhim. Zh 2009, 81:80-84.
44. Ungvari Z., Labinskyy N., Gupte S., Chander P.N., Edwards J.G., Csiszar A. Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats. Am. J. Physiol. Heart Circ. Physiol 2008, 294:H2121-H2128.
45. Vitali M., Venturelli E., Galimberti D., Benerini-Gatta L., Scarpini E., Finazzi D. Analysis of the genes coding for subunit 10 and 15 of cytochrome c oxidase in Alzheimer's disease. J. Neural Transm 2009, 116:1635-1641.
46. Wang J., Green P.S., Simpkins J.W. Estradiol protects against ATP depletion, mitochondrial membrane potential decline and the generation of reactive oxygen species induced by 3-nitroproprionic acid in SK-N-SH human neuroblastoma cells. J. Neurochem 2001, 77:804-811.
47. Wang X., Dykens J.A., Perez E., Liu R., Yang S., Covey D.F., Simpkins J.W. Neuroprotective effects of 17beta-estradiol and nonfeminizing estrogens against H2O2 toxicity in human neuroblastoma SK-N-SH cells. Mol. Pharmacol 2006, 70:395-404.
48. Wolter K.G., Hsu Y.T., Smith C.L., Nechushtan A., Xi X.G., Youle R.J. Movement of Bax from the cytosol to mitochondria during apoptosis. J. Cell Biol 1997, 139:1281-1292.
49. Wu M., Neilson A., Swift A.L., Moran R., Tamagnine J., Parslow D., Armistead S., Lemire K., Orrell J., Teich J., Chomicz S., Ferrick D.A. Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells. Am. J. Physiol. Cell. Physiol 2007, 292:C125-C136.
50. Yan L.J., Christians E.S., Liu L., Xiao X., Sohal R.S., Benjamin I.J. Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage. EMBO J. 2002, 21:5164-5172.
51. Yan L.J., Sohal R.S. Mitochondrial adenine nucleotide translocase is modified oxidatively during aging. Proc. Natl. Acad. Sci. U. S. A 1998, 95:12896-12901.
52. Yan L.J., Yang S.H., Shu H., Prokai L., Forster M.J. Histochemical staining and quantification of dihydrolipoamide dehydrogenase diaphorase activity using blue native PAGE. Electrophoresis 2007, 28:1036-1045.
53. Yang Q., Sakurai T., Jing X., Utsunomiya H., Shan L., Nakamura Y., Nakamura M., Oura S., Suzuma T., Yoshimura G., Umemura T., Kokawa Y., Kakudo K. Expression of Bcl-2, but not Bax, correlates with estrogen receptor status and tumor proliferation in invasive breast carcinoma. Pathol. Int 1999, 49:775-780.
54. Yi K.D., Covey D.F., Simpkins J.W. Mechanism of okadaic acid-induced neuronal death and the effect of estrogens. J. Neurochem 2009, 108:732-740.
55. Zaldivar V., Magri M.L., Zarate S., Jaita G., Eijo G., Radl D., Ferraris J., Pisera D., Seilicovich A. Estradiol increases the Bax/Bcl-2 ratio and induces apoptosis in the anterior pituitary gland. Neuroendocrinology 2009, 90:292-300.