-
1
-
-
53649096054
-
Malaria research in the post-genomic era
-
Winzeler E.A. Malaria research in the post-genomic era. Nature 2008, 455:751-756.
-
(2008)
Nature
, vol.455
, pp. 751-756
-
-
Winzeler, E.A.1
-
2
-
-
77952696164
-
Drug discovery: priming the antimalarial pipeline
-
Fidock D.A. Drug discovery: priming the antimalarial pipeline. Nature 2011, 465:297-298.
-
(2011)
Nature
, vol.465
, pp. 297-298
-
-
Fidock, D.A.1
-
3
-
-
77952704258
-
Thousands of chemical starting points for antimalarial lead identification
-
Gamo F.J., Sanz L.M., Vidal J., et al. Thousands of chemical starting points for antimalarial lead identification. Nature 2010, 465:305-310.
-
(2010)
Nature
, vol.465
, pp. 305-310
-
-
Gamo, F.J.1
Sanz, L.M.2
Vidal, J.3
-
4
-
-
34347264532
-
Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target
-
Kuntz A.N., Davioud-Charvet E., Sayed A.A., et al. Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target. PLoS Med. 2007, 4:e206.
-
(2007)
PLoS Med.
, vol.4
-
-
Kuntz, A.N.1
Davioud-Charvet, E.2
Sayed, A.A.3
-
5
-
-
47349121027
-
Glutathione reductase and thioredoxin reductase at the crossroad: the structure of Schistosoma mansoni thioredoxin glutathione reductase
-
Angelucci F., Miele A.E., Boumis G., et al. Glutathione reductase and thioredoxin reductase at the crossroad: the structure of Schistosoma mansoni thioredoxin glutathione reductase. Proteins 2008, 72:936-945.
-
(2008)
Proteins
, vol.72
, pp. 936-945
-
-
Angelucci, F.1
Miele, A.E.2
Boumis, G.3
-
6
-
-
77957793022
-
Mapping the catalytic cycle of Schistosoma mansoni thioredoxin glutathione reductase by X-ray crystallography
-
Angelucci F., Dimastrogiovanni D., Boumis G., et al. Mapping the catalytic cycle of Schistosoma mansoni thioredoxin glutathione reductase by X-ray crystallography. J. Biol. Chem 2010, 285:32557-32567.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 32557-32567
-
-
Angelucci, F.1
Dimastrogiovanni, D.2
Boumis, G.3
-
7
-
-
0037135586
-
Thioredoxin reductase is essential for the survival of Plasmodium falciparum erythrocytic stages
-
Krnajski Z., Gilberger T.W., Walter R.D., et al. Thioredoxin reductase is essential for the survival of Plasmodium falciparum erythrocytic stages. J. Biol. Chem. 2002, 277:25970-25975.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25970-25975
-
-
Krnajski, Z.1
Gilberger, T.W.2
Walter, R.D.3
-
8
-
-
40149085227
-
New uses for old drugs Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: Mechanistic and pharmacological implications
-
Sannella A.R., Casini A., Gabbiani C., et al. New uses for old drugs Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: Mechanistic and pharmacological implications. FEBS Lett. 2008, 582:844-847.
-
(2008)
FEBS Lett.
, vol.582
, pp. 844-847
-
-
Sannella, A.R.1
Casini, A.2
Gabbiani, C.3
-
9
-
-
79951861884
-
Bioinorganic and medicinal chemistry: aspects of gold(I)-protein complexes
-
Bhabak K.P., Bhuyan B.J., Mugesh G. Bioinorganic and medicinal chemistry: aspects of gold(I)-protein complexes. Dalton Trans 2011, 40:2099-2111.
-
(2011)
Dalton Trans
, vol.40
, pp. 2099-2111
-
-
Bhabak, K.P.1
Bhuyan, B.J.2
Mugesh, G.3
-
10
-
-
43249126995
-
Inhibition of cathepsin B by Au(I) complexes: a kinetic and computational study
-
Gunatilleke S.S., de Oliveira C.A., McCammon J.A., et al. Inhibition of cathepsin B by Au(I) complexes: a kinetic and computational study. J. Biol. Inorg. Chem. 2008, 13:555-561.
-
(2008)
J. Biol. Inorg. Chem.
, vol.13
, pp. 555-561
-
-
Gunatilleke, S.S.1
de Oliveira, C.A.2
McCammon, J.A.3
-
12
-
-
70350351432
-
Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects
-
Angelucci F., Sayed A.A., Williams D.L., et al. Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects. J. Biol. Chem. 2009, 284:28977-28985.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 28977-28985
-
-
Angelucci, F.1
Sayed, A.A.2
Williams, D.L.3
-
13
-
-
0027136282
-
Comparative protein modelling by satisfaction of spatial restraints
-
Sali A., Blundell T.L. Comparative protein modelling by satisfaction of spatial restraints. J. Mol. Biol. 1993, 234:779-815.
-
(1993)
J. Mol. Biol.
, vol.234
, pp. 779-815
-
-
Sali, A.1
Blundell, T.L.2
-
14
-
-
33645504195
-
Identification of correct regions in protein models using structural alignment, and consensus information
-
Wallner B., Elofsson A. Identification of correct regions in protein models using structural alignment, and consensus information. Protein Sci. 2006, 15:900-913.
-
(2006)
Protein Sci.
, vol.15
, pp. 900-913
-
-
Wallner, B.1
Elofsson, A.2
-
15
-
-
54949097750
-
MetaMQAP: a meta-server for the quality assessment of protein models
-
Pawlowski M., Gajda M.J., Matlak R., et al. MetaMQAP: a meta-server for the quality assessment of protein models. BMC Bioinformatics 2008, 9:403.
-
(2008)
BMC Bioinformatics
, vol.9
, pp. 403
-
-
Pawlowski, M.1
Gajda, M.J.2
Matlak, R.3
-
16
-
-
70349932423
-
AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility
-
Morris G.M., Huey R., Lindstrom W., et al. AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility. J. Comput. Chem. 2009, 30:2785-2791.
-
(2009)
J. Comput. Chem.
, vol.30
, pp. 2785-2791
-
-
Morris, G.M.1
Huey, R.2
Lindstrom, W.3
-
17
-
-
52449135496
-
Organogold complexes probe a large beta-barrel cavity for human serum alpha1-acid glycoprotein
-
Zsila F., Bikadi Z., Hazai E., et al. Organogold complexes probe a large beta-barrel cavity for human serum alpha1-acid glycoprotein. Biochim. Biophys. Acta 2008, 1784:1106-1114.
-
(2008)
Biochim. Biophys. Acta
, vol.1784
, pp. 1106-1114
-
-
Zsila, F.1
Bikadi, Z.2
Hazai, E.3
-
18
-
-
21144455675
-
The functional role of selenocysteine (Sec) in the catalysis mechanism of large thioredoxin reductases: proposition of a swapping catalytic triad including a Sec-His-Glu state
-
Brandt W., Wessjohann L.A. The functional role of selenocysteine (Sec) in the catalysis mechanism of large thioredoxin reductases: proposition of a swapping catalytic triad including a Sec-His-Glu state. Chembiochem 2005, 6:386-394.
-
(2005)
Chembiochem
, vol.6
, pp. 386-394
-
-
Brandt, W.1
Wessjohann, L.A.2
-
19
-
-
0030725657
-
Identification and characterization of the functional amino acids at the active site of the large thioredoxin reductase from Plasmodium falciparum
-
Gilberger T.W., Walter R.D., Muller S. Identification and characterization of the functional amino acids at the active site of the large thioredoxin reductase from Plasmodium falciparum. J. Biol. Chem. 1997, 272:29584-29589.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 29584-29589
-
-
Gilberger, T.W.1
Walter, R.D.2
Muller, S.3
-
20
-
-
79959805617
-
Investigations of the catalytic mechanism of thioredoxin glutathione reductase from Schistosoma mansoni
-
Huang H.H., Day L., Cass C.L., et al. Investigations of the catalytic mechanism of thioredoxin glutathione reductase from Schistosoma mansoni. Biochemistry 2011, 50:5870-5882.
-
(2011)
Biochemistry
, vol.50
, pp. 5870-5882
-
-
Huang, H.H.1
Day, L.2
Cass, C.L.3
-
21
-
-
0034683041
-
First crystal structure of a medicinally relevant gold protein complex: unexpected binding of
-
Zou J., Taylor P., Dornan J., et al. First crystal structure of a medicinally relevant gold protein complex: unexpected binding of. Angew. Chem. Int. Ed. 2000, 39:2931-2934.
-
(2000)
Angew. Chem. Int. Ed.
, vol.39
, pp. 2931-2934
-
-
Zou, J.1
Taylor, P.2
Dornan, J.3
-
22
-
-
1542358787
-
Prediction and functional analysis of native disorder in proteins from the three kingdoms of life
-
Ward J.J., Sodhi J.S., McGuffin L.J., et al. Prediction and functional analysis of native disorder in proteins from the three kingdoms of life. J. Mol. Biol. 2004, 337:635-645.
-
(2004)
J. Mol. Biol.
, vol.337
, pp. 635-645
-
-
Ward, J.J.1
Sodhi, J.S.2
McGuffin, L.J.3
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