Specific nitration of tyrosines 46 and 48 makes cytochrome c assemble a non-functional apoptosome

FEBS Letters

Volumn 586, Issue 2, 2012, Pages 154-158

  García Heredia, José M ^a   Díaz Moreno, Irene ^a   Díaz Quintana, Antonio ^a   Orzáez, Mar ^b   Navarro, José A ^a   Hervás, Manuel ^a   De La Rosa, Miguel A ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

^b CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

Author keywords

Apoptosome; Caspase 9 activation; Cytochrome c; Cytochrome c oxidase; Electron transfer; Mitochondrial respiration; Post translational modification; RNOS; Tyrosine nitration

Indexed keywords

APOPTOSOME; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 9; CYTOCHROME C; CYTOCHROME C OXIDASE; PEROXIDASE; SOLVENT; TYROSINE;

ARTICLE; CELL DEATH; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME KINETICS; HUMAN; NITRATION; NITROSATIVE STRESS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN MODIFICATION;

APOPTOSOMES; CASPASES; CYTOCHROMES C; ELECTRON TRANSPORT; ENZYME ACTIVATION; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; NITROSATION; OXIDATION-REDUCTION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SUBSTRATE SPECIFICITY; TYROSINE;

EID: 84855806389     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.12.007     Document Type: Article

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