How chromatin prevents genomic rearrangements: Locus colocalization induced by transcription factor binding

BioEssays

Volumn 34, Issue 2, 2012, Pages 90-93

  Déjardin, Jérôme ^a  

^a INSTITUTE OF HUMAN GENETICS   (France)

Author keywords

Heterochromatin; Nuclear organization; Telomere; Transcription factor

Indexed keywords

HORMONE RECEPTOR; TELOMERASE; TRANSCRIPTION FACTOR;

ARTICLE; CHROMATIN; CHROMATIN STRUCTURE; CHROMOSOMAL INSTABILITY; CHROMOSOME ABERRATION; CHROMOSOME SIZE; CHROMOSOME TRANSLOCATION; DNA BINDING; DNA REPAIR; DNA STRUCTURE; FACE MALFORMATION; GENE LOCATION; GENE REARRANGEMENT; GENETIC RECOMBINATION; HETEROCHROMATIN; TELOMERE ALTERNATIVE LENGTHENING;

ANIMALS; CENTROMERE; CHROMATIN; DNA; DNA-BINDING PROTEINS; HOMOLOGOUS RECOMBINATION; HUMANS; PROMOTER REGIONS, GENETIC; TELOMERE; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC;

EID: 84855800095     PISSN: 02659247     EISSN: 15211878     Source Type: Journal    
DOI: 10.1002/bies.201100122     Document Type: Article

References (33)

1. Mao YS, Zhang B, Spector DL. 2011. Biogenesis and function of nuclear bodies. Trends Genet 27: 295-306.
2. Fodor BD, Shukeir N, Reuter G, Jenuwein T. 2010. Mammalian Su(var) genes in chromatin control. Annu Rev Cell Dev Biol 26: 471-501.
3. Misteli T, Soutoglou E. 2009. The emerging role of nuclear architecture in DNA repair and genome maintenance. Nat Rev Mol Cell Biol 10: 243-54.
4. Nikiforova MN, Stringer JR, Blough R, Medvedovic M, et al. 2000. Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells. Science 290: 138-41.
5. Roix JJ, McQueen PG, Munson PJ, Parada LA, et al. 2003. Spatial proximity of translocation-prone gene loci in human lymphomas. Nat Genet 34: 287-91.
6. Neves H, Ramos C, da Silva MG, Parreira A, et al. 1999. The nuclear topography of ABL, BCR, PML, and RARalpha genes: evidence for gene proximity in specific phases of the cell cycle and stages of hematopoietic differentiation. Blood 93: 1197-207.
7. Lin C, Yang L, Tanasa B, Hutt K, et al. 2009. Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell 139: 1069-83.
8. Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, et al. 2005. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310: 644-8.
9. Mani RS, Tomlins SA, Callahan K, Ghosh A, et al. 2009. Induced chromosomal proximity and gene fusions in prostate cancer. Science 326: 1230.
10. Hu Q, Kwon YS, Nunez E, Cardamone MD, et al. 2008. Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules. Proc Natl Acad Sci USA 105: 19199-204.
11. Belmont AS. 2010. Estrogen fueled, nuclear kiss: Did it move for you? Nucleus 1: 440-3.
12. Kocanova S, Kerr EA, Rafique S, Boyle S, et al. 2010. Activation of estrogen-responsive genes does not require their nuclear co-localization. PLoS Genet 6: e1000922.
13. Hakim O, Sung MH, Voss TC, Splinter E, et al. 2011. Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements. Genome Res 21: 697-706.
14. Dunham MA, Neumann AA, Fasching CL, Reddel RR. 2000. Telomere maintenance by recombination in human cells. Nat Genet 26: 447-50.
15. Cesare AJ, Reddel RR. 2010. Alternative lengthening of telomeres: models, mechanisms and implications. Nat Rev Genet 11: 319-30.
16. Luderus ME, van Steensel B, Chong L, Sibon OC, et al. 1996. Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex. J Cell Biol 135: 867-81.
17. Draskovic I, Arnoult N, Steiner V, Bacchetti S, et al. 2009. Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination. Proc Natl Acad Sci USA 106: 15726-31.
18. Dejardin J, Kingston RE. 2009. Purification of proteins associated with specific genomic loci. Cell 136: 175-86.
19. Ehrlich M, Sanchez C, Shao C, Nishiyama R, et al. 2008. ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation. Autoimmunity 41: 253-71.
20. Luciani JJ, Depetris D, Usson Y, Metzler-Guillemain C, et al. 2006. PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase. J Cell Sci 119: 2518-31.
21. Yehezkel S, Segev Y, Viegas-Pequignot E, Skorecki K, et al. 2008. Hypomethylation of subtelomeric regions in ICF syndrome is associated with abnormally short telomeres and enhanced transcription from telomeric regions. Hum Mol Genet 17: 2776-89.
22. John S, Sabo PJ, Thurman RE, Sung MH, et al. 2011. Chromatin accessibility pre-determines glucocorticoid receptor binding patterns. Nat Genet 43: 264-8.
23. Sekinger EA, Moqtaderi Z, Struhl K. 2005. Intrinsic histone-DNA interactions and low nucleosome density are important for preferential accessibility of promoter regions in yeast. Mol Cell 18: 735-48.
24. Hewitt SL, Yin B, Ji Y, Chaumeil J, et al. 2009. RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. Nat Immunol 10: 655-64.
25. Noordermeer D, de Wit E, Klous P, van de Werken H, et al. 2011. Variegated gene expression caused by cell-specific long-range DNA interactions. Nat Cell Biol 13: 944-51.
26. Chen JD, Chan CS, Pirrotta V. 1992. Conserved DNA binding and self-association domains of the Drosophila zeste protein. Mol Cell Biol 12: 598-608.
27. Mahmoudi T, Katsani KR, Verrijzer CP. 2002. GAGA can mediate enhancer function in trans by linking two separate DNA molecules. EMBO J 21: 1775-81.
28. Yusufzai TM, Tagami H, Nakatani Y, Felsenfeld G. 2004. CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species. Mol Cell 13: 291-8.
29. Kersten S, Kelleher D, Chambon P, Gronemeyer H, et al. 1995. Retinoid X receptor alpha forms tetramers in solution. Proc Natl Acad Sci USA 92: 8645-9.
30. Garcia-Cao M, O'Sullivan R, Peters AH, Jenuwein T, et al. 2004. Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. Nat Genet 36: 94-9.
31. Gonzalo S, Jaco I, Fraga MF, Chen T, et al. 2006. DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat Cell Biol 8: 416-24.
32. Gibbons RJ, McDowell TL, Raman S, O'Rourke DM, et al. 2000. Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation. Nat Genet 24: 368-71.
33. Heaphy CM, de Wilde RF, Jiao Y, Klein AP, et al. 2011. Altered telomeres in tumors with ATRX and DAXX mutations. Science 333: 425.