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Volumn 47, Issue 1, 2012, Pages 337-344

6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site

Author keywords

Anacardic acid; Epigenetics; Histone acetylation; Histone acetyltransferase (HAT); Inhibitors

Indexed keywords

ACETYL COENZYME A; ANACARDIC ACID; HISTONE ACETYLTRANSFERASE; HISTONE H3; HISTONE H4; RECOMBINANT ENZYME; TIP60; UNCLASSIFIED DRUG;

EID: 84855795338     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.11.001     Document Type: Article
Times cited : (104)

References (36)
  • 4
    • 0028287786 scopus 로고
    • Tyrosinase inhibitors from Anacardium occidentale fruits
    • I. Kubo, I. Kinst-Hori, and Y. Yokokawa Tyrosinase inhibitors from Anacardium occidentale fruits J. Nat. Prod. 57 1994 545 551
    • (1994) J. Nat. Prod. , vol.57 , pp. 545-551
    • Kubo, I.1    Kinst-Hori, I.2    Yokokawa, Y.3
  • 5
    • 0037294820 scopus 로고    scopus 로고
    • Design, synthesis and biological evaluation of benzimidazole/ benzothiazole and benzoxazole derivatives as cyclooxygenase inhibitors
    • R. Paramashivappa, P. Phani Kumar, P.V. Subba Rao, and A. Srinivasa Rao Design, synthesis and biological evaluation of benzimidazole/benzothiazole and benzoxazole derivatives as cyclooxygenase inhibitors Bioorg. Med. Chem. Lett. 13 2003 657 660
    • (2003) Bioorg. Med. Chem. Lett. , vol.13 , pp. 657-660
    • Paramashivappa, R.1    Phani Kumar, P.2    Subba Rao, P.V.3    Srinivasa Rao, A.4
  • 6
    • 20744457367 scopus 로고    scopus 로고
    • Lipoxygenase inhibitory activity of anacardic acids
    • T.J. Ha, and I. Kubo Lipoxygenase inhibitory activity of anacardic acids J. Agric. Food Chem. 53 2005 4350 4354
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 4350-4354
    • Ha, T.J.1    Kubo, I.2
  • 8
    • 33746581782 scopus 로고    scopus 로고
    • Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation
    • Y. Sun, X. Jiang, S. Chen, and B.D. Price Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation FEBS Lett. 580 2006 4353 4356
    • (2006) FEBS Lett. , vol.580 , pp. 4353-4356
    • Sun, Y.1    Jiang, X.2    Chen, S.3    Price, B.D.4
  • 9
    • 47049097388 scopus 로고    scopus 로고
    • Histone acetyltransferase inhibitor anacardic acid causes changes in global expression during in vitro plasmodium falciparum development
    • L. Cui, J. Miao, T. Furuya, Q. Fan, X. Li, P.K. Rathod, X. Su, and L. Cui Histone acetyltransferase inhibitor anacardic acid causes changes in global expression during in vitro plasmodium falciparum development Eukaryotic. Cell 7 2008 1200 1210
    • (2008) Eukaryotic. Cell , vol.7 , pp. 1200-1210
    • Cui, L.1    Miao, J.2    Furuya, T.3    Fan, Q.4    Li, X.5    Rathod, P.K.6    Su, X.7    Cui, L.8
  • 10
    • 58949095757 scopus 로고    scopus 로고
    • Bisubstrate inhibitors of the MYST HATs Esa1 and Tip60
    • J. Wu, N. Xie, Z. Wu, Y. Zhang, and Y.G. Zheng Bisubstrate inhibitors of the MYST HATs Esa1 and Tip60 Bioorg. Med. Chem. 17 2009 1381 1386
    • (2009) Bioorg. Med. Chem. , vol.17 , pp. 1381-1386
    • Wu, J.1    Xie, N.2    Wu, Z.3    Zhang, Y.4    Zheng, Y.G.5
  • 11
    • 54849423666 scopus 로고    scopus 로고
    • Synthesis of benzamides related to anacardic acid and their histone acetyltransferase (HAT) inhibitory activities
    • J.A. Souto, M. Conte, R. Alvarez, A. Nebbioso, V. Carafa, L. Altucci, and A.R. de Lera Synthesis of benzamides related to anacardic acid and their histone acetyltransferase (HAT) inhibitory activities ChemMedChem. 3 2008 1435 1442
    • (2008) ChemMedChem. , vol.3 , pp. 1435-1442
    • Souto, J.A.1    Conte, M.2    Alvarez, R.3    Nebbioso, A.4    Carafa, V.5    Altucci, L.6    De Lera, A.R.7
  • 12
    • 77955473296 scopus 로고    scopus 로고
    • Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative
    • M. Ghizzoni, A. Boltjes, C. Graaf, H.J. Haisma, and F.J. Dekker Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative Bioorg. Med. Chem. 18 2010 5826 5834
    • (2010) Bioorg. Med. Chem. , vol.18 , pp. 5826-5834
    • Ghizzoni, M.1    Boltjes, A.2    Graaf, C.3    Haisma, H.J.4    Dekker, F.J.5
  • 13
    • 34748861551 scopus 로고    scopus 로고
    • Characterization of novel inhibitors of histone acetyltransferases
    • E.D. Eliseeva, V. Valkov, M. Jung, and M.O. Jung Characterization of novel inhibitors of histone acetyltransferases Mol. Cancer Ther. 6 2007 2391
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 2391
    • Eliseeva, E.D.1    Valkov, V.2    Jung, M.3    Jung, M.O.4
  • 15
    • 33947532026 scopus 로고    scopus 로고
    • Histone acetyltransferase complexes: One size doesn't fit all
    • K.K. Lee, and J.L. Workman Histone acetyltransferase complexes: one size doesn't fit all Nat. Rev. Mol. Cell Biol. 8 2007 284 295
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 284-295
    • Lee, K.K.1    Workman, J.L.2
  • 16
    • 32444434989 scopus 로고    scopus 로고
    • Histone H4-K16 acetylation controls chromatin structure and protein interactions
    • M. Shogren-Knaak, H. Ishii, J.M. Sun, M.J. Pazin, J.R. Davie, and C.L. Peterson Histone H4-K16 acetylation controls chromatin structure and protein interactions Science 311 2006 844 847
    • (2006) Science , vol.311 , pp. 844-847
    • Shogren-Knaak, M.1    Ishii, H.2    Sun, J.M.3    Pazin, M.J.4    Davie, J.R.5    Peterson, C.L.6
  • 17
    • 27944448727 scopus 로고    scopus 로고
    • Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription
    • F. Faiola, X. Liu, S. Lo, S. Pan, K. Zhang, E. Lymar, A. Farina, and E. Martinez Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription Mol. Cell. Biol. 25 2005 10220 10234
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 10220-10234
    • Faiola, F.1    Liu, X.2    Lo, S.3    Pan, S.4    Zhang, K.5    Lymar, E.6    Farina, A.7    Martinez, E.8
  • 19
    • 7044250740 scopus 로고    scopus 로고
    • Lysine acetylation and the bromodomain: A new partnership for signaling
    • X.J. Yang Lysine acetylation and the bromodomain: a new partnership for signaling Bioessays 26 2004 1076 1087
    • (2004) Bioessays , vol.26 , pp. 1076-1087
    • Yang, X.J.1
  • 22
    • 70349311616 scopus 로고    scopus 로고
    • Histone acetyl transferases as emerging drug targets
    • F.J. Dekker, and H.J. Haisma Histone acetyl transferases as emerging drug targets Drug Discov. Today 14 2009 942 948
    • (2009) Drug Discov. Today , vol.14 , pp. 942-948
    • Dekker, F.J.1    Haisma, H.J.2
  • 23
    • 2342599619 scopus 로고    scopus 로고
    • The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases
    • X.J. Yang The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases Nucleic Acids Res. 32 2004 959 976
    • (2004) Nucleic Acids Res. , vol.32 , pp. 959-976
    • Yang, X.J.1
  • 24
    • 33845746277 scopus 로고    scopus 로고
    • Pharmacological targeting of lysine acetyltransferases in human disease: A progress report
    • D.M. Heery, and P.M. Fischer Pharmacological targeting of lysine acetyltransferases in human disease: a progress report Drug Discov. Today 12 2007 88 99
    • (2007) Drug Discov. Today , vol.12 , pp. 88-99
    • Heery, D.M.1    Fischer, P.M.2
  • 25
    • 79958189845 scopus 로고    scopus 로고
    • Histone acetyltransferases are crucial regulators in NF-kappaB mediated inflammation
    • M. Ghizzoni, H.J. Haisma, H. Maarsingh, and F.J. Dekker Histone acetyltransferases are crucial regulators in NF-kappaB mediated inflammation Drug Discov. Today 16 2011 504 511
    • (2011) Drug Discov. Today , vol.16 , pp. 504-511
    • Ghizzoni, M.1    Haisma, H.J.2    Maarsingh, H.3    Dekker, F.J.4
  • 26
    • 33645987615 scopus 로고    scopus 로고
    • Epigenetic control using natural products and synthetic molecules
    • T. Suzuki, and N. Miyata Epigenetic control using natural products and synthetic molecules Curr. Med. Chem. 13 2006 935 958
    • (2006) Curr. Med. Chem. , vol.13 , pp. 935-958
    • Suzuki, T.1    Miyata, N.2
  • 27
    • 20344392202 scopus 로고    scopus 로고
    • Epigenetics - An epicenter of gene regulation: Histones and histone-modifyng enzymes
    • M. Biel, V. Wascholowski, and A. Giannis Epigenetics - an epicenter of gene regulation: histones and histone-modifyng enzymes Angew. Chem. Int. Ed. 44 2005 3186 3216
    • (2005) Angew. Chem. Int. Ed. , vol.44 , pp. 3186-3216
    • Biel, M.1    Wascholowski, V.2    Giannis, A.3
  • 28
    • 50249091120 scopus 로고    scopus 로고
    • Chemical regulation of epigenetic modifications: Opportunities for new cancer therapy
    • Y.G. Zheng, J. Wu, Z. Chen, and M. Goodman Chemical regulation of epigenetic modifications: opportunities for new cancer therapy Med. Res. Rev. 28 2008 645 687
    • (2008) Med. Res. Rev. , vol.28 , pp. 645-687
    • Zheng, Y.G.1    Wu, J.2    Chen, Z.3    Goodman, M.4
  • 29
    • 46749127067 scopus 로고    scopus 로고
    • Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis
    • B. Sung, M.K. Pandey, K.S. Ahn, T. Yi, M.M. Chaturvedi, M. Liu, and B.B. Aggarwal Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis Blood 111 2008 4880 4891
    • (2008) Blood , vol.111 , pp. 4880-4891
    • Sung, B.1    Pandey, M.K.2    Ahn, K.S.3    Yi, T.4    Chaturvedi, M.M.5    Liu, M.6    Aggarwal, B.B.7
  • 30
    • 47049097388 scopus 로고    scopus 로고
    • Histone acetyltransferase inhibitor anacardic acid causes changes in global gene expression during in vitro Plasmodium falciparum development, Eukaryot
    • L. Cui, J. Miao, T. Furuya, Q. Fan, X. Li, P.K. Rathod, X.Z. Su, and L. Cui Histone acetyltransferase inhibitor anacardic acid causes changes in global gene expression during in vitro Plasmodium falciparum development, Eukaryot Cell 7 2008 1200 1210
    • (2008) Cell , vol.7 , pp. 1200-1210
    • Cui, L.1    Miao, J.2    Furuya, T.3    Fan, Q.4    Li, X.5    Rathod, P.K.6    Su, X.Z.7    Cui, L.8
  • 34
    • 78651490914 scopus 로고    scopus 로고
    • Development of specific "drug-Like Property" Rules for carboxylate-containing Oral drug Candidates
    • A. Böcker, P.R. Bonneau, O. Hucke, A. Jakalian, and P.J. Edwards Development of specific "Drug-Like Property" Rules for carboxylate-containing Oral drug Candidates ChemMedChem 12 2010 2102 2113
    • (2010) ChemMedChem , vol.12 , pp. 2102-2113
    • Böcker, A.1    Bonneau, P.R.2    Hucke, O.3    Jakalian, A.4    Edwards, P.J.5
  • 36
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • J.D. Dignam, R.M. Lebovitz, and R.G. Roeder Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei Nucleic Acids Res. 11 1983 1475 1489
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3


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