MEK1/2 dual-specificity protein kinases: Structure and regulation

Biochemical and Biophysical Research Communications

Volumn 417, Issue 1, 2012, Pages 5-10

  Roskoski, Robert ^a  

^a Blue Ridge Institute for Medical Research   (United States)

Author keywords

Catalytic spine; ERK; KSR; MAPK; PAK; PKA; RAF; RAS; Regulatory spine; Scaffold

Indexed keywords

KINASE SUPPRESSOR OF RAS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PROTEIN KINASE; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CATALYSIS; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME STRUCTURE; HUMAN; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SHORT SURVEY; SIGNAL TRANSDUCTION;

ANIMALS; CATALYTIC DOMAIN; ENZYME ACTIVATION; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MICE; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY;

EID: 84855795110     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.11.145     Document Type: Short Survey

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