Synthesis, anti-inflammatory activity and molecular docking studies of 2,5-diarylfuran amino acid derivatives

European Journal of Medicinal Chemistry

Volumn 47, Issue 1, 2012, Pages 52-58

  Stefani, Hélio A ^a   Botteselle, Giancarlo V ^a   Zukerman Schpector, Julio ^b   Caracelli, Ignez ^b   Da Silva Corrêa, Denis ^b   Farsky, Sandra H P ^a   MacHado, Isabel D ^a   Santin, José R ^a   Hebeda, Cristina B ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

Author keywords

2,5 Diarylfuran; Amino acids; COX 1 and COX 2; Docking; Suzuki Miyaura

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; FURAN DERIVATIVE; LIPOPOLYSACCHARIDE; PROSTAGLANDIN E2;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING SITE; DRUG STRUCTURE; DRUG SYNTHESIS; MOLECULAR DOCKING; NEUTROPHIL; PROSTAGLANDIN RELEASE;

AMINO ACIDS; ANTI-INFLAMMATORY AGENTS; CATALYTIC DOMAIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; MODELS, MOLECULAR;

EID: 84855775159     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.10.018     Document Type: Article

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