Synthesis and evaluation of novel chromogenic peptidase substrates based on 9-(4′-aminophenyl)-10-methylacridinium salts as diagnostic tools in clinical bacteriology

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 2, 2008, Pages 832-835

  Anderson, Rosaleen J ^a   Groundwater, Paul W ^a   Huang, Yongxue ^a   James, Arthur L ^b   Orenga, Sylvain ^c   Rigby, Annette ^b   Roger Dalbert, Céline ^c   Perry, John D ^d  

^a UNIVERSITY OF SUNDERLAND   (United Kingdom)

^b NORTHUMBRIA UNIVERSITY   (United Kingdom)

^c BIOMÉRIEUX   (France)

^d FREEMAN HOSPITAL   (United Kingdom)

Author keywords

Alanine aminopeptidase; 9 (4 Aminophenyl) 10 methylacridinium salt; Alanine aminopeptidase; Chromogenic peptidase substrate; Clinical bacteriology; Cystic fibrosis; Diagnostic reagent; Microorganism detection; Microorganism differentiation

Indexed keywords

9 (4' AMINOPHENYL) 10 METHYLACRIDINIUM SALT; 9 [4' N (ALANYLALANYLALANYL)AMINOPHENYL] 10 METHYLACRIDINIUM BISTRIFLUOROACETATE; 9 [4' N (BETA ALANYL)AMINOPHENYL] 10 METHYLACRIDINIUM BISTRIFLUOROACETATE; 9 [4' N (N ALPHA TERT BUTOXYCARBONYLALANYLALANYLALANYL)AMINOPHENYL] 10 METHYLACRIDINIUM IODIDE; 9 [4' N (PYROGLUTAMINYL)AMINOPHENYL] 10 METHYLACRIDINIUM IODIDE; ACRIDINE DERIVATIVE; CHROMOGENIC SUBSTRATE; PEPTIDASE; REAGENT; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; BACTERIUM COLONY; BACTERIUM CULTURE; BACTERIUM DETECTION; DIAGNOSTIC TEST; ENZYME ACTIVITY; ENZYME SUBSTRATE; NONHUMAN;

ACRIDINES; BACTERIAL INFECTIONS; PEPTIDE HYDROLASES; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS);

EID: 38349070369     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.11.018     Document Type: Article

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