Decreased oxygen tension lowers reactive oxygen species and apoptosis and inhibits osteoblast matrix mineralization through changes in early osteoblast differentiation

Journal of Cellular Physiology

Volumn 227, Issue 4, 2012, Pages 1309-1318

  Nicolaije, Claudia ^a   Koedam, Marijke ^a   van Leeuwen, Johannes P T M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; CASPASE 3; COLLAGEN; CYTOCHROME C; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE 23B; METALLOPROTEINASE; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BONE MATRIX; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN CELL; MITOCHONDRION; OSTEOBLAST; OXIDATIVE STRESS; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

APOPTOSIS; BONE MATRIX; CALCIFICATION, PHYSIOLOGIC; CATALASE; CELL DIFFERENTIATION; CELL HYPOXIA; CELL LINE; CELL PROLIFERATION; COLLAGEN; GENE EXPRESSION; HUMANS; OSTEOBLASTS; OXYGEN; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 84855733202     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22841     Document Type: Article

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