Diastereo- and enantioselective synthesis of fluorinated proline derivatives via copper(I)-catalyzed asymmetric 1,3-dipolar cycloaddition

Synthesis

Volumn 2012, Issue 2, 2012, Pages 265-271

  Li, Qing ^a   Ding, Chang Hua ^a   Li, Xiao Hui ^b   Weissensteiner, Walter ^c   Hou, Xue Long ^a,b  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c UNIVERSITY OF VIENNA   (Austria)

Author keywords

1,3 dipolar cycloaddition; asymmetric catalysis; azomethine ylides; copper; fluorinated prolines

Indexed keywords

1 ,3-DIPOLARCYCLOADDITION; ASYMMETRIC CATALYSIS; AZOMETHINE YLIDES; CYCLOADDITION REACTION; DIASTEREO- AND ENANTIOSELECTIVITY; ENANTIOSELECTIVE SYNTHESIS; FLUORINATED PROLINES; HIGH YIELD; NITROALKENES; OPTICALLY ACTIVE; PROLINE DERIVATIVES; SIMPLE APPROACH;

AMINO ACIDS; AROMATIC POLYMERS; CATALYSIS; CHELATION; COPPER; ENANTIOSELECTIVITY; INORGANIC COMPOUNDS; SYNTHESIS (CHEMICAL);

CYCLOADDITION;

2 (METHOXYCARBONYL) 4 NITRO 5 PHENYL 3 (TRIFLUOROMETHYL)PYRROLIDINE; 2 (METHOXYCARBONYL) 4 NITRO 5,3 TOLYL 3 (TRIFLUOROMETHYL)PYRROLIDINE; 2 (METHOXYCARBONYL) 4 NITRO 5,4 TOLYL 3 (TRIFLUOROMETHYL)PYRROLIDINE; 2 (METHOXYCARBONYL) 5 (4 METHOXYPHENYL) 4 NITRO 3 (TRIFLUOROMETHYL)PYRROLIDINE; 3 (BROMODIFLUOROMETHYL) 2 (METHOXYCARBONYL) 4 NITRO 5 PHENYLPYRROLIDINE; 3 (CHLORODIFLUOROMETHYL) 2 (METHOXYCARBONYL) 4 NITRO 5 PHENYLPYRROLIDINE; 3 (DIFLUOROMETHYL) 2 (METHOXYCARBONYL) 4 NITRO 5 PHENYLPYRROLIDINE; 4 AMINO 2 (METHOXYCARBONYL) 5,3 TOLYL 3 (TRIFLUOROMETHYL)PYRROLIDINE; 5 (3 BROMOPHENYL) 2 (METHOXYCARBONYL) 4 NITRO 3 (TRIFLUOROMETHYL)PYRROLIDINE; 5 (4 BROMOPHENYL) 2 (METHOXYCARBONYL) 4 NITRO 3 (TRIFLUOROMETHYL)PYRROLIDINE; 5 (4 CHLOROPHENYL) 2 (METHOXYCARBONYL) 4 NITRO 3 (TRIFLUOROMETHYL)PYRROLIDINE; COPPER; COPPER PERCHLORATE; LIGAND; PROLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC CATALYSIS; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; CYCLOADDITION; DIASTEREOSELECTIVITY; ENANTIOSELECTIVITY; FLUORINATION; STEREOCHEMISTRY; SYNTHESIS;

EID: 84855730820     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0031-1289653     Document Type: Article

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