Peptidyl prolyl cis/trans-isomerases: Comparative reactivities of cyclophilins, FK506-binding proteins, and parvulins with fluorinated oligopeptide and protein substrates

Biochemistry

Volumn 44, Issue 49, 2005, Pages 16026-16034

  Golbik, Ralph ^a   Yu, Chao ^b   Weyher Stingl, Elisabeth ^c   Huber, Robert ^c   Moroder, Luis ^c   Budisa, Nediljko ^c   Schiene Fischer, Cordelia ^b  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b MAX PLANCK RESEARCH UNIT FOR ENZYMOLOGY OF PROTEIN FOLDING   (Germany)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; HYDROGEN; ISOMERS; SUBSTRATES;

PEPTIDE BONDS; PROLYL BONDS;

PROTEINS;

4 FLUOROPROLINE DERIVATIVE; 4 NITROANILIDE DERIVATIVE; ALANINE; ANILIDE; CYCLOPHILIN; CYSTEINE; ENZYME VARIANT; FK 506 BINDING PROTEIN; FLUORINE; HYDROGEN; OLIGOPEPTIDE; PARVULIN; PHENYLALANINE; PROLINE; PROLINE DERIVATIVE; PYRROLIDINE DERIVATIVE; SERINE; TETRAPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; CATALYST; CHEMICAL BOND; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; ISOMERIZATION; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; STEREOSPECIFICITY;

BACTERIAL PROTEINS; BINDING SITES; CYCLOPHILINS; ENZYME INHIBITORS; FLUORINE; HUMANS; MODELS, MOLECULAR; PEPTIDES; PEPTIDYLPROLYL ISOMERASE; PROTEIN CONFORMATION; PROTEIN FOLDING; SUBSTRATE SPECIFICITY; TACROLIMUS BINDING PROTEINS;

ESCHERICHIA COLI;

EID: 28944453311     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051442w     Document Type: Article

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