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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 2, 2012, Pages 814-819

Design, synthesis, and structure-activity relationship studies of conformationally restricted mutilin 14-carbamates

(8) Fu, Liqiang a Liu, Xin a Ling, Chenyu a Cheng, Jianjun a Guo, Xingsheng a He, Huili a Ding, Shi a Yang, Yushe a

a SHANGHAI INSTITUTE OF MATERIA MEDICA (China)

Author keywords

Conformationally restriction; Gram positive bacteria; Pleuromutilin

Indexed keywords

ANTIINFECTIVE AGENT; CARBAMIC ACID; LINEZOLID; MUTILIN 14 CARBAMATE; RETAPAMULIN; SB 222734; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG CONFORMATION; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; GRAM POSITIVE BACTERIUM; METHICILLIN RESISTANT STAPHYLOCOCCUS EPIDERMIDIS; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STAPHYLOCOCCUS EPIDERMIDIS; STREPTOCOCCUS PNEUMONIA; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; CARBAMATES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; MICROBIAL SENSITIVITY TESTS; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STEREOISOMERISM; STREPTOCOCCUS PNEUMONIAE; STRUCTURE-ACTIVITY RELATIONSHIP;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; POSIBACTERIA; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STREPTOCOCCUS;

EID: 84855713200 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.12.063 Document Type: Article

Times cited : (25)

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